TMT Archives

A deeper look at carrier proteome effects for single-cell proteomics

This publication by the Olsen group at University of Copenhagen describes the carrier proteome effects in single cell proteomics with mixed species TMTpro-labeled samples. Using the 30 SPD method, they show that quantitative precision and signal intensity are limited...

Evosep One enables robust deep proteome coverage using tandem mass tags while significantly reducing instrument time

by Eva Bryderup

Jonathan Krieger, PhD, Senior Applications Scientist at Bioinformatics Solutions presented “Evosep One Enables Robust Deep Proteome Coverage Using Tandem Mass Tags while Significantly Reducing Instrument Time” showcasing recent data from the SPARC Biocentre at the Hospital for Sick Children.

Basement membrane stiffness determines metastases formation

by Eva Bryderup

In this study, the Erler group from the BRIC Institute at University of Copenhagen, Denmark identifies Net4 as a key regulator of basement membrane stiffness, a special type of extracellular matrix, which presents the major barrier cancer cells have to overcome...