New Innovation at Hupo

As we get ready for this year’s HUPO 2022 in Cancun, Mexico, we can already reveal that we will feature a programme filled with new innovations, scientific presentations, and networking opportunities. 

We look forward to announcing a new high throughput method as well as automated workflows which are critical to large cohort studies and ultimately bringing proteomics to the clinic. 

For a widespread adaptation of proteomics in the clinic, the entire workflow from sample preparation through to data analysis needs to be fast and robust to enable the required throughput. Therefore, we introduce a fully automated end-to-end sample preparation workflow starting from protein to tryptic peptides loaded on Evotips and applied to a clinical cohort of patient plasma samples. 

Get an overview below of all our HUPO 2022 activities.

 

Hupo 2022 Pre-Congress Panel Discussion Workshop

Sunday, december 4, 2022: 13.00-14:00

Standardization in MS-based Proteomics

Join us for a scientific discussion of the importance of standardized workflows for LC-MS proteomics. Learn more at HUPO 2022.

Speakers:

Jennifer Van Eyk
Leader of clinical proteomics, Cedars-Sinar Medical center

Phil Robinson
Professor, Children’s Medical Research Institute

Hanno Steen, Director of Proteomics and Associate Professor, Boston Children’s Hospital

Science, food and fun

Evosep User Appreciation Event

Monday, December 5, 2022: 18:30 – 22:30 – Mextreme, Boulevard Kukulcan, Zona Hotelera, Cancún

Join us Monday, December 5 to our User Appreciation Event and meet company experts as well as fellow Evosep One users for networking and knowledge exchange. 

The event is held at Restaurante Mextreme, right across Cancun Convention Center.

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SCIEX MEETING

Rapid and robust proteomes with standardized methods on the Evosep One powered by zEno-swath

Tuesday, December 6, 2022: 08:00 – 09:00 – Grand cancun 5 ballroom

Talk by Dorte Bekker-Jensen, Scientist at Evosep

Mass spectrometry-based clinical proteomics is becoming increasingly popular and provides a powerful set of technologies, with the potential to revolutionize health care and enable precision medicine. We specifically designed and developed the Evosep One for high-throughput applications, with a focus on clinical analysis of large sample cohorts. The newest and most powerful generation of mass spectrometers combined with novel acquisition strategies and software tools keep pushing boundaries and are now making comprehensive proteomes in short time a reality.

Here we evaluated the new ZenoTOF 7600 mass spectrometer with the novel ZenoSWATH acquisition strategy across the Evosep One standard methods. For high-throughput applications with 200 samples analyzed per day, we were able to reproducible identify and quantify more than 4,000 proteins from 200 ng HeLa digest. Collectively our results show that ZenoSWATH is a significant driver of deep proteomes, making the ZenoTOF 7600 an ideal match with high-throughput and standardized methods on the Evosep One.

See more at HUPO 2022

This event is hosted by

AGILENT Meeting

ULTRA-HIGH SENSITIVITY FOR TARGETED PROTEOMIC USING EVOSEP-MRM AT SINGLE CELL LEVEL

Tuesday, December 6, 2022: 08:00 – 09:00

Talk by Nicolai Bache, Head of Applications at Evosep

Join this event to explore the power of single cell proteomics. The Evosep One is a powerful and standardized platform for high sensitivity work including single cell proteomics. The robustness and throughput of the Whisper methods on the Evosep One combined with the sensitivity of the Agilent 6495C triple quadrupole support targeted analysis of proteomes at the single cell level. We demonstrated this by targeting selected peptides in a complex background of sub nanogram material combined with dilution curves spanning several orders of magnitude. To ensure seamless integration of the EvosepOne with the Agilent 6495C triple quadrupole, we have developed a native driver for MassHunter and a robust solution for the Agilent nanoflow ion source.

See more at HUPO 2022

This event is hosted by

Poster sessions

This year you can explore a lot of new research featuring Evosep One at HUPO. Below you can find a complete list of all the submitted abstracts featuring the Evosep One. Meet the Evosep team at the orange poster sessions!

Monday 05-12-2022

  • PP01.209: Applying 16s Sequencing, in-Silico Spectral Library Generation and SWATH for Deep Clinical Metaproteomic Analysis
    Dr. Tariq Ganief, Lecturer, IDM
  • PP01.064: Mass-Spectrometry Based Proteomic Based Diagnostics of Viral Meningitis and Lyme Neuroborreliosis
    Dr. Lylia Drici, Postdoc, Copenhagen University
  • PP01.082: Application of In-Cell Fast Photochemical Oxidation of Proteins for the Study of Organoids
    Miss Raquel Shortt, PhD. candidate, University of Maryland
  • PP01.126: Companion Diagnostics and Precision Proteomics-based Translational Biomarker Analysis for Improved Disease Diagnostics and Prognostics
    Assoc. Prof. Allan Stensballe, Associate Professor, Aalborg University
  • PP01.130: Ultra-high Sensitivity for Targeted Clinical Proteomics using Evosep-MRM
    Dr. Ole Vorm, Founder & Chairman, Evosep

Tuesday 06-12-2022

  • PP02.022: Ultrafast Bacterial Detection in Urinary Tract Infections using High-throughput Proteomics and Artificial Intelligence
    Mrs. Florence Roux-Dalvai, CHU de Québec, University of Laval
  • PP02.029: Profiling Reactive and Functional Cysteines of Transcription Factors using Cellular Fractionation and an Electrophilic Probe
    Dr. Daniele Canzani, Manager, Proteomics, Talus Bio
  • PP02.085: A Pipeline for the Time Efficient Analysis of Thousands of LC/MS Runs in High Performance Computing Environment
    Mr. Patrik van Zalm, PhD. student, Boston Children’s Hospital
  • PP02.109: High Throughput Analysis of Parkinson’s Disease PBMC with DIA-FAIMS
    Mr. Dani Flinkman, PhD. student, Lund University
  • PP02.136: Proteome Analysis of FFPE and Fresh-frozen Meningeal Tumor Tissue
    Mr. Ole Østergaard, Postdoc, NNF Center for Protein Research, Copenhagen University
  • PP02.138: Mass Spectrometry-based Proteomics on Parkinson’s Disease Post-mortem Human Brain.
    Ms. Débora Pita Illobre, PhD. candidate, Center for Neurogenomics and Cognitive Research
  • PP02.152: Interaction Proteomics of Alzheimer’s Disease-associated Proteins from Post-mortem Human Brains
    Ms. Evangelia Thanou, PhD. candidate, Vrije Universiteit Amsterdam

Wednesday 07-12-2022

  • PP03.039: Versatility of TimsTOF Platforms for 4-D High Throughput and Sensitive Proteomics Studies
    Dr. Diego Assis, Proteomics Applications Specialist, Bruker
  • PP03.041: A Complete and Automated Sample Preparation Strategy for High-throughput and Standardized Proteomics Applied to a Cohort of Patient Plasma Samples
    Mrs. Dorte Bekker-Jensen, Senior Scientist, Evosep
  • PP03.042: Pushing the Boundaries for Robust and High-throughput Single Cell Analysis with Whisper Flow Technology Powered by dia-PASEF
    Mrs. Dorte Bekker-Jensen, Senior Scientist, Evosep
  • PP03.064: Fast Duty Cycle Differential Mobility Separation (DMS-TOF) to Increase Selectivity in SWATH Analysis.
    Dr. Yves Le Blanc, Chief Research Scientist, SCIEX
  • PP03.087: Quantification of Spliceosome Proteins in Neuroblastoma Cells after Drug Treatments using Nuclear Proteome Extraction, SP3 Digestion, and Data-independent Acquisition
    Ms. Andrea Gutierrez, Senior Research Associate, Talus Bioscience
  • PP03.120: Internal TMT-Based Standard Curve for the Absolute Quantitation of Plasma Proteins by Parallel Reaction Monitoring Mass Spectrometry (PRM-MS)
    Dr. Christoph Borchers, Professor and Director, McGill University / Lady Davis Institute

MEET THE TEAM 

This year you can meet both representatives from our Applications-, Management-, Sales- and Product team. Learn a little bit about the team at HUPO here. 

Nicolai Bache

Nicolai Bache

Head of Applications

Dorte Bekker-Jensen

Dorte Bekker-Jensen

Senior Scientist

Michael BarRett Andersen

Michael BarRett Andersen

Head of Product Management

Erik Verschuuren

Erik Verschuuren

Head of Global Sales

Ole Vorm

Ole Vorm

Founder

Thomas Carrell

Thomas Carrell

Sales Specialist

LET’S GET IN TOUCH

We are always open to answering questions and form new collaborations, so don’t hesitate to reach out. Fill out our contact form and we’ll do our very best to assist you.