Evotips

Simplifying workflows by
speeding up sample loading
and reducing carry-over

High efficiency disposable trap colulmn

The high-efficiency disposable trap column in the Evosep system significantly reduces overhead time and increases sample throughput.

This makes workflows more efficient and allows for the analysis of larger sample sets in less time. The Evotip technology simplifies and enhances the proteomic analysis of minimal cell quantities and liquid biopsies, setting a new standard in sensitivity, throughput, and robustness.

20% increased recovery through fewer transfer steps
Up to 80% utilization of the processed sample

Explore the benefits and see how efficient sample capture and recovery
streamlines high-sensitivity workflows.

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No carryover with the Evotip, even for challenging sample types

Scaling plasma proteomics to thousands of patient samples demands workflows that are not only robust and reproducible but also cost-efficient and contamination-free.

In our latest application note, we demonstrate how Evosep-based workflows powered by Evotip Pure enable the analysis of over 1,100 plasma samples in under 7 days with ultra-low carryover (<0.2%), even in complex matrices. The disposable Evotip design safeguards the LC system and ensures consistent performance across large cohorts, eliminating cross-contamination and preserving sample integrity.

This study highlights how automation, miniaturization, and smart integration with Evosep make large-scale plasma proteomics not just accessible, but reliable and scalable.

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Improved column longevity powered by the Evotip Pure

The Evosep Eno is built for standardization – this means fixed methods with specified columns – setting you up for immediate success.

The key to this lies in the nature of the Evotip Pure, which functions as a disposable trap column that safeguards the LC system and chromatographic column. This becomes crucial when analyzing more challenging sample types like body fluids, FFPE or tissue samples by combining the clean-up step with partial elution of the peptides of interest.

This is demonstrated through exceptional stability and reliability for large-scale plasma proteomics, processing ~400 sample injections with a consistent pressure profile (<1% CV) and no systematic pressure build-up, confirming its suitability for continuous high-throughput operation.

Additional resources

Get to know Evosep and our technology through the experiences of those using it daily. Discover all publications our users and collaboration partners or dive into our many applications and tech notes.