LITERATURE ROOM
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Title | Material | Year | Authors | Organization | Evosep method | MS instrumentation | Learn More | hf:tax:evosep_method | hf:tax:ms_vendor |
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Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha | Publication | 2025 | Lawson, Andrew Michael Frey, Iglika Ivanova, Eva Adam, Christopher J. Lord, Simon Cockell, Jonathan Coxhead, Nikoletta Negy, David Adams, Marta Szell, Matthias Trost, Muzlifah Haniffa, Simon P. Mackay, Neil Perkins, Neil Rajan | Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. | Whisper 20 SPD | Bruker timsTOF HT | whisper-20spd | bruker-timstof-ht | |
C-terminal amides mark proteins for degradation via SCF–FBXO31 | Publication | 2025 | Hofmann, Lukas T. Henneberg, Moritz M. Pfleiderer, Annina Denoth-Lippuner, Fillip Kalčic, Ajse S. Nievergelt, Marwa Peters Al-Bayati, Nikolaos D. Sidiropoulos, Viola Beier, Matthias Mann, Sebastian Jessberger, Martin Jinek, Brenda A. Schulman, Jeffrey W. | Institute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland, Laboratory for Organic Chemistry, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technolog | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise | Publication | 2025 | Ben Stocks, Julia Prats Quesada, Anthony M. Mozzicato, Carolina Jacob, Simone Jensen, Kirstin A. McGregor, Jens Bangsbo, Juleen R. Zierath, Morten Hostrup, Atul S. Deshmukh | Phosphoproteomic mass spectrometry analyses were performed by the Proteomics Research nfrastructure (PR) at the University of openhagen (UP), supported by the ovo ordisk Foundation (F) (gr | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
A rapid genome-proteome approach to identify rate-limiting steps in the butyrate production pathway in probiotic Clostridium butyricum, CBM588. | Publication | 2025 | Liam Wood, Bunmi B. Omorotionmwan, Adam M. Blanchard, Adam Dowle, David Tooth, Tom S. Bailey, Ruth Griffin | Vaccines and Therapeutics Group, Biodiscovery Institute, School of Life Sciences, University of Nottingham, University Park, Nottingham, UK | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Milk-derived antimicrobial peptide GMp7: Disrupting protein networks for multi-target antibacterial inhibition and enhanced dairy preservation | Publication | 2025 | Jinze He, Hong Li, Yujuan Xu, Yufang Li, Tingting Yang, Xiaoyan Yu, Xue Yang, Aixiang Huang, Yuanshan Yu, Yanan Shi | Sericultural & Agri-Food Research Institute, Guandong Academy of Agricultural Sciences, Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Product Processing, Guangzhou, 510610, China | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease | Publication | 2025 | Marcell Harhai, Mads M. Foged, Emeline Recazens, Miriam Lisci, Sylvain Chollet, Juan C. Landoni, Nora Laban, Saliana Manley, Jose Antonio Lopez-Escamez, Anna Lysakowski, Alexis A. Jourdain | Department of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland | Extended method | Bruker timsTOF Pro | extended-method | bruker-timstof-pro | |
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma | Publication | 2025 | Kirit Singh, Matthew W. Foster, Marlene J. Violette, Annam: Corcoran, Kelly M, Hotchkiss, Chelsea O. Railton, Emily E. Blandford, Kathryn E. Blethen, Elizabeth L. Thomas, David M. Ashley, Annick Desjardins, Henry S. Friedman, Margaret O. Johnson, Allan Fr | The Preston Robert Tisch Brain Tumor Center at Duke University; Durham, NC, US, Department of Neurosurgery, Duke University; NC, US | 100 SPD, 60 SPD | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | 100-spd 60-spd | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
Predicting Protein Pathways Associated to Tumor Heterogeneity by Correlating Spatial Lipidomics and Proteomics: The Dry Proteomic Concept | Publication | 2025 | Laurine Lagache, Yanis Zirem, Émilie Le Rhun, Isabelle Fournier, Michel Salzet | Univ.Lille, Inserm, CHU Lille, U1192 – Proteomics Inflammatory Response Mass Spectrometry- PRISM, Lille, France | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth | Publication | 2025 | Zhongze Li, Minjae Kim, Jose Roberto da Silva Nascimento, Bertrand Legeret, Gabriel Lemes Jorge, Marie Bertrand, Fred Beisson Jay J. Thelen, Yonghua Li-Bisson | Aix-Marseille Université, CEA, CNRS, Institute of Biosciences and Biotechnologies of Aix-Marseille, UMR 7265, CEA Cadarache, Saint-Paul-lez Durance, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Characterisation of a Chondrus crispus Stakehouse Hydrolysate for Functional,Nutritional and Bioactive Benefits and Application as an Emulsifier in Baked Goods | Publication | 2025 | Dolly Bhati, Leticia Mora, Maria Hayes | Food BioSciences, Teagasc Food Research Centre, Dunsinea Lane, Ashtown, D15 DY05 Dublin, Ireland | 30 SPD | Bruker timsTOF fleX | 30-spd | bruker-timstof-flex | |
Harnessing Filamentous Fungi for Enzyme Cocktail Production Through Rice Bran Bioprocessing | Publication | 2025 | Ana M. Yélamos, Jose F. Marcos, Paloma Manzanares, Sandra Garrigues | Food Biotechnology Department, Instituto de Agroquímica y Technología de Alimentos (IATA), Consejo Superior de Investigaciones Científicas (CSIC), Catedrático Augustín Escardino Benlloch 7, 46980, Valencia, Spain | 100 SPD, 30 SPD | Bruker timsTOF fleX, Thermo Orbitrap Exploris 240 | 100-spd 30-spd | bruker-timstof-flex thermo-orbitrap-exploris-240 | |
The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice | Publication | 2025 | Irene Santos-García, Pablo Bascuñana, Mirjam Brackhan, María Villa, Ivan Eiriz, Thomas Brüning, Jens Pahnke | Translational Neurodegeneration Research and Neuropathology Lab, Department of Clinical Medicine (KlinMed), Medical Faculty, University of Oslo (UiO) and Section of Neuropathology Research, Department of Pathology (PAT), Clinics for Laboratory Medicine (K | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Discovery of Chemical Tools for Polysorbate-Degradative Enzyme Control in Biopharmaceutical Upstream Process via Multi-Omic Profiling of Host Cell Clones | Publication | 2025 | Taku Tsukidate, Ansum Sahoo, Geetanjali Pendyala, Rong-Sheng Yang, Jonathan Welch, Sri Madabhushi, Xuanwen Li | Analytical Research & Development Mass Spectrometry, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States. | Extended method | Bruker timsTOF Pro 2 | extended-method | timstof-pro-2 | |
Modulation of biological activities in adipose derived stem cells by histone deacetylation | Publication | 2025 | Sallam Abdallah, Mouna Tabebi, Sawsan Qanadilo, Neserin Ali, Jing Wang, Pádraig D'Arcy, Wen Zhong, Folke Sjoberg, Moustafa Elmasry, Ahmed El-Serafi | The Department of Biomedical and Clinical Sciences (BKV), Lindköping University, Lindköping, Sweden | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies | Publication | 2025 | Georgia Mitsa, Livia Florianova, Josiane Lafleur, Adriana Aguilar-Mahecha, Rene P. Zahedi, Sonia V. del Rincon, Mark Basik, Christoph H. Borchers, Gerald Batist | Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal H3T 1E2, Canada, Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital and McGill University, Montréal H3T 1E2, C | Extended method | Thermo Q Exactive Plus | extended-method | thermo-q-exactive-plus | |
Challenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics | Publication | 2025 | Matt Spick, Cheryl M. Isherwood, Lee A. Gethings, Christopher J. Hughes, Matthew E. Daly, Hana Hassanin, Daan R. van der Veen, Debra J. Skene, Jonathan D. Johnston | School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK | 60 SPD | Waters SYNAPT XS | 60-spd | waters-synapt-xs | |
Histone methyltransferase DOT1L maintains identity and restricts cytotoxic potential of CD8 T cells | Publication | 2025 | Muddassir Malik, Willem-Jan de Leeuw, Muhammad Assad Aslam, Eliza Mari Kwesi-Maliepaard, Teun van den Brand, Bram van den Broek, Maxime Kempers, Liesbeth Hoekman, Nathalie Proost, Tibor van Welsem, Elzo de Wit, Jannie Borst, Heinz Jacobs, Fred van Leeuwen | Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands | Extended method | Thermo Orbitrap Exploris 480 |
| extended-method | thermo-orbitrap-exploris-480 |
Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease | Publication | 2025 | Alejandro Pinto, Hazal Haytural, Cássio Morais Loss, Claudia Alvarez, Asude Ertas, Olivia Curtis, Alyssa R. Williams, Grayson Murphy, Ken Salleng, Sylvia Gografe, Ali Altıntaş, Tal Kafri, Romain Barres, Atul S. Deshmukh, Henriette van Praag | Stiles-Nicholson Brain Institute, Charles E. Schmidt College of Medicine, Florida Atlantic University, Jupiter, FL 33458, USA | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | Publication | 2025 | Jonathan A. Chapman, Andrea C. Masi, Lauren C. Beck, Hannah Watson, Gregory R. Young, Hillary P. Browne, Yan Shao, Raymond Kiu, Andrew Nelson, Jenifer A. Doyle, Pawel Plamowski, Márton Lengyel, James P. R. Connolly, Christopher A. Lamb, Andrew Porter, Tre | Newcastle University, Translational and Clinical Research Institute, Newcastle upon Tyne, NE2 4HH, UK | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Intestinal enteroendocrine cell subtype differentiation and hormone production in zebrafish | Publication | 2025 | Margaret Morash, Richard G. Kay, Erik J. Soderblom, Grace H. MacLean, Jia Wen, Peyton J. Moore, Colin R. Lickwar, Fiona M. Gribble, Frank Reimann, Rodger A. Liddle, John F. Rawls | Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. | 30 SPD | Thermo Orbitrap Astral | 30-spd | thermo-orbitrap-astral | |
Pupylation-based proximity labeling reveals regulatory factors in cellulose biosynthesis in Arabidopsis | Publication | 2025 | Shuai Zheng, Lise C. Noack, Ouda Khammy, Andreas De Meyer, Ghazanfar Abbas Khan, Nancy De Winne, Dominique Eeckhout, Daniël Van Damme, Staffan Persson | Copenhagen Plant Science Center, Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Molecular Mechanisms of Acanthamoeba castellanii Response to Different Sources of Oxidative Stress | Publication | 2025 | Kateřina Ženíšková, Pavel Stopka, Tania Martín-Pérez, Guillaume Chevreux, Maria Grechnikova, Eliška Drncová, Ronald Malych, Jan Mach, Julia Walochnik, Jean-Michel Camadro, Robert Sutak | Department of Parasitology, Faculty of Science, BIOCEV, Charles University, Vestec 25250, Czech Republic | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Proteomics Reveals Distinctive Host Cell Protein Expression Patterns in Fed-Batch and Perfusion Cell Culture Processes | Publication | 2025 | Ansuman Sahoo, Taku Tsukiadate, Bor-Ruei Lin, Erin Kotzbauer, Jason Houser, Misaal Patel, Xuanwen Li, Sri Ranganayaki Madabhushi | Biologics Process Research & Development, Merck & Co., Inc., Rahway, New Jersey, USA 2 Analytical Research & Development Mass Spectrometry, Merck &Co., Inc., Rahway, New Jersey, USA | 100 SPD, 60 SPD | Bruker timsTOF Pro 2 | 100-spd 60-spd | timstof-pro-2 | |
Identification of novel Kv1.3 channel-interacting proteins using proximity labelling in T-cells | Publication | 2025 | Dilpreet Kour, Christine A. Bowen, Upasna Srivastava, Hai M. Nguyen, Rashmi Kumari, Prateek Kumar, Amanda D. Brandelli, Sara Bitarafan, Brendan R Tobin, Levi Wood, Nicholas T. Seyfried, Heike Wulff, Srikant Rangaraju | Department of Neurology, School of Medicine, Yale University, New Haven (CT), USA, Center for Neurodegenerative Diseases, Emory University, Atlanta (GA), USA, Department of Biochemistry, Emory University, Atlanta (GA), USA | 30 SPD | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | 30-spd | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
Comparison of the amyloid plaque proteome in Down syndrome, early-onset Alzheimer’s disease, and late-onset Alzheimer’s disease | Publication | 2025 | Mitchell Martá‑Ariza, Dominique F. Leitner, Evgeny Kanshin, Jianina Suazo, Ana Giusti Pedrosa, Manon Thierry, Edward B. Lee, Orrin Devinsky, Eleanor Drummond, Juan Fortea, Alberto Lleó, Beatrix Ueberheide, Thomas Wisniewski | Department of Neurology, NYU Grossman School of Medicine, New York, NY, USA, | Extended method | Thermo Q Exactive HF-X | extended-method | thermo-q-exactive-hf-x | |
Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics | Publication | 2025 | Xiang Zheng, Andreas Mund, Matthias Mann | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen 2200, Copenhagen, Denmark | Whisper 40 SPD | Bruker timsTOF SCP, Thermo Orbitrap Astral |
| whisper-40spd | bruker-timstof-scp thermo-orbitrap-astral |
Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures | Publication | 2025 | Caroline R. Espada, Christian Anthon, Rubens D.M. Magalhães, José Carlos Quilles Junior, Natalia M.M. Teles, Fabiano Pais, Lissur A. Orsine, Letícia de Almeida, Tânia P. A. Defina, Adam Dowle, Jan Gorodkin, Pegine B. Walrad, Angela K. Cruz | Department of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo FMRP-USP, Ribeirão Preto, São Paulo, Brasil | 100 SPD | Bruker timsTOF HT | 100-spd | bruker-timstof-ht | |
IP-to-MS: An Unbiased Workflow for Antigen Profiling | Publication | 2025 | Stephanie Biedka, Svitlana Yablonska, Xi Peng, Duah Alkam, Mara Hartoyo, Hannah VanEvery, Daniel J. Kass, Stephanie D. Byrum, Kunhong Xiao, Yingze Zhang, Robyn T. Domsic, Robert Lafyatis, Dana P. Ascherman, Jonathan S. Minden | Impact Proteomics, LLC., Pittsburgh, Pennsylvania 15206, United States, | 100 SPD | Bruker timsTOF Pro 2, Thermo Orbitrap Exploris 480 |
| 100-spd | timstof-pro-2 thermo-orbitrap-exploris-480 |
Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics | Publication | 2025 | Zilu Ye, Pierre Sabatier, Leander van der Hoeven, Maico Y. Lechner, Teeradon Phlairaharn, Ulises H. Guzman, Zhen Liu, Haoran Huang, Min Huang, Xiangjun Li, David Hartlmayr, Fabiana Izaguirre, Anjali Seth, Hiren J. Joshi, Sergey Rodin, Karl-Henrik Grinnemo | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark | Whisper Zoom 120 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Thermo Orbitrap Astral |
| whisper-zoom-120-spd whisper-zoom-40-spd whisper-zoom-80-spd | thermo-orbitrap-astral |
Multi-omics analysis of keratinocytes reveals dermokine-dependent regulation of cell-cell adhesion via p120 | Publication | 2025 | Vahap Canbay, Till Wüstemann, Weihua Tian, Tobias A. Beyer, Camilla Reiter Elbæk, Michael Stumpe, Gaetana Restivo, Chatpakorn Christiansen, Anabel Migenda Herranz, Susanne Mailand, Jürg Hafner, Rune Busk Damgaard, Steffen Goletz, Jörn Dengjel, Ulrich auf | Department for Bioengineering and Biomedicine, Technical University of Denmark, 2800, Copenhagen, Denmark. | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation | Publication | 2025 | Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger | Proteomics Science Technology Platform, The Francis Crick Institute, London, UK, Molecular Structure of Cell Signalling Laboratory, The Francis Crick Institute, London, UK, Crick-GSK Biomedical LinkLabs, GSK, Stevenage, Hertfordshire, UK | 100 SPD, 60 SPD | Bruker timsTOF Pro 2 |
| 100-spd 60-spd | timstof-pro-2 |
AUTO-SP: automated sample preparation for analyzing proteins and protein modifications | Publication | 2025 | T. Mamie Lih, Liyuan Jiao, Lijun Chen, Jongmin Woo, Yuefan Wang, Hui Zhang | Department of Pathology, John Hopkins University School of Medicine, Baltimore, Maryland, United States, Department of Oncology, Sidney Kimmel Cancer Center at John Hopkins Medical Institutions, Baltimore, Maryland, United States, Department of Urology, J | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Centromere inactivation during aging can be rescued in human cells | Publication | 2025 | Sweta Sikder, Songjoon Baek, Truman Mcneail, Yamini Dalal | Center for Cancer Research, National Cancer Institute/NIH, Bethesda, MD 20892, USA, Saint Olaf College, 1520 St. Olaf Avenue, Northfield, MN 55057, USA | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
COA5 has an essential role in the early stage of mitochondrial complex IV assembly | Publication | 2025 | Jia Xin Tang, Alfredo Cabrera-Orefice, Jana Meisterknecht, Lucie S Taylor, Geoffray Monteuuis, Maria Ekman Stensland, Adam Szczepanek, Karen Stals, James Davison, Langping He, Sila Hopton, Tuula A Nyman, Christopher B Jackson, Angela Pyle, Monika Winter, | Mitochondrial Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome | Publication | 2025 | Veronica Muratore, Claudia Guinea-Pérez, Álvaro Serrano, Coralia Pérez, Sandra CanoLópez, Ainhoa Urcullu, Mikel Azkargorta, Ibon Iloro, Carles Galdeano, Jordi Juárez-Jiménez, Ugo Mayor, Felix Elortza, Rosa Barrio, James D. Sutherland | Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research 10 and Technology Alliance (BRTA), Derio, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Determination of collagen types and mineral contents in fish skin and collagen-containing skin-derived protein hydrolysates before and after in vitro simulated digestion | Publication | 2025 | Min Wang, Yixuan Liu, Noelia Pallarés, Zouhir el Marsni, Katerina Kousoulaki, and Francisco J. Barba | Research group in Innovative Technologies for Sustainable Food (ALISOST), Department of Preventive Medicine and Public Health, Valencia, Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Functional and Potential BioactiveHealth Benefits of Selected MicroalgalHydrolysates Assessed In Silico and InVitro | Publication | 2025 | Elena Aurino, Leticia Mora, Antonio Marzocchella, Christina M. Kuchendorf, Bärbel Ackermann and Maria Hayes | Dipartimento di Ingegneria Chimica, dei Materiali, e della Produzione Industriale, Università degli Studi di Napoli ‘Federico II’, Naples, Italien | 30 SPD | Bruker timsTOF fleX | 30-spd | bruker-timstof-flex | |
Modeling the acutely injured brain environment in vitro | Publication | 2025 | Rocío Bartolomé,Alessia Ferrarini, Juan Antonio López, Elisa Murenu, BenediktBerninger, Felipe Ortega, Magdalena Götz, Christophe Heinrich,Sergio Gascón | Department of Molecular, Cellular and Developmental Neurobiology, Cajal Institute – CSIC, Spain | 15 SPD | Thermo Orbitrap Eclipse | 15-spd | thermo-orbitrap-eclipse | |
Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes | Publication | 2025 | Diana Samodova, Evelina Stankevic, Mathilde Sonne Søndergaard, Naiyu Hu, Tarunveer S. Ahluwalia, Daniel R. Witte, Daniel Belstrøm, Anniek Frederike Lubberding, Pratik D. Jagtap, Torben Hansen & Atul S. Deshmukh | Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
eIF2α Phosphorylation-ATF4 Axis-Mediated Transcriptional Reprogramming Mitigates Mitochondrial Impairment During ER Stress | Publication | 2025 | Hien Thi Le, Jiyoung Yu, Hee Sung Ahn, Mi-Jeong Kim, In Gyeong Chae, Hyun-Nam Cho, Juhee Kim, Hye-Kyung Park, Hyuk Nam Kwon, Han-Jung Chae, Byoung Heon Kang, Jeong Kon Seo, Kyunggon Kim, Sung Hoon Back | School of Biological Sciences, University of Ulsan, Ulsan, Korea | Whisper 20 SPD | Bruker timsTOF Pro 2 | whisper-20spd | timstof-pro-2 | |
Biofabrication of anisotropic articular cartilage based on decellularized extracellular matrix | Publication | 2025 | Anna Puiggalí-Jou, Isabel Hui, Lucrezia Baldi, Rea Frischknecht, Maryam Asadikorayem, Jakub Janiak, Parth Chansoria, Maxwell C McCabe, Martin J Stoddart, Kirk C Hansen, Karen L Christman and Marcy Zenobi-Wong | Tissue Engineering + Biofabrication Laboratory, Department of Health Sciences & Technology, ETH Zürich, Zürich, Switzerland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains | Publication | 2025 | Nicholas Norris, Cesar L. Moreno, Joshua W. C. Maxwell, G. Gregory Neely, Richard J. Payne, Melkam A. Kebede, Ramona J. Bieber Urbauer, Freda H. Passam, Mark Larance & Robert S. Haltiwanger | Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA | 60 SPD | SCIEX ZenoTOF 7600 | 60-spd | sciex-zenotof-7600 | |
Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation | Publication | 2025 | Yingqian Li, Natalie Proost, Marieke van de Ven, Olaf van Tellingen, Onno B. Bleijerveld, John B.A.G. Haanen, Johanna Olweus, Reuven Agami | Division of Oncogenomics, Oncode institute, the Netherlands Cancer Institute, Amsterdam, the Netherlands | 30 SPD | Thermo Q Exactive 480 | 30-spd | thermo-q-exactive-480 | |
A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities | Publication | 2025 | Andrea Schuhmann, Damarys Loew, Karl Mechtler, Mariette Matondo, Mandy Rettel, Dominic Helm, Francis Impens, Simon Devos, Anna Shevchenko, Paolo Nanni, Eduard Sabidó | Centre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Free amino acids accelerate the time-dependent inactivation of rat liver nucleotide pyrophosphatase/phosphodiesterase Enpp3 elicited by EDTA | Publication | 2024 | Ana Romero, Guadalupe Cumplido-Laso, Ascensión Fernández, Javier Moreno, José Canales, Rui Ferreira, Juan López-Gómez, João Meireles Ribeiro, María Jesús Costas & José Carlos Cameselle | Departamento de Bioquímica y Biología Molecular y Genética, Facultad de Medicina y Ciencias de la Salud, Universidad de Extremadura, Badajoz, Spain | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Amyloid beta precursor protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) | Publication | 2024 | Sara Bagnoli, Frauke van Bebber, Lisa Adam, Farzana Shamim-Schulze, Oliver Ohlenschläger, Martin Bens, Emilio Cirri, Adam Antebi, Ivan Matić, Anja Schneider, Bettina Schmid, Alessandro Cellerino, Janine Kirstein, Dario Riccardo Valenzano | Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), Jena, Germany | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP | Publication | 2024 | Andrew Leduc, Luke Khoury, Joshua Cantlon, Saad Khan, Nikolai Slavov | Departments of Bioengineering, Biology, Chemistry and Chemical Biology, Single Cell Proteomics Center, and Barnett Institute, Northeastern University, Boston, MA, USA. | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Protein aggregation capture assisted profiling of the thiol redox proteome | Publication | 2024 | Ana Martinez-Val, Samuel Lozano-Juárez, Jorge Lumbreras, Irene Rodríguez, Marinela Couselo-Seijas, Ana Simón-Chica, Carlos Galán-Arriola, Rodrigo Fernández, Estefanía Núñez, Inmaculada Jorge, David Filgueiras-Rama, Borja Ibáñez, Jesús Vázquez | Cardiovascular Proteomics Laboratory, Centro Nacional de Investigaciones, Cardiovasculares Carlos III (CNIC), Madrid, Spain | 15 SPD | Thermo Orbitrap Eclipse Tribid | 15-spd | thermo-orbitrap-eclipse-tribid | |
Multi-tiered proteome analysis displays the hyper-permeability of the rheumatoid synovial compartment for plasma proteins | Publication | 2024 | Eva Maria Stork, Sofia Kalaidopoulou Nteak, Danique M.H. van Rijswijck, J. Mirjam A. Damen, Hans Ulrich Scherer, Rene E.M. Toes, Albert Bondt, Tom W.J. Huizinga, Albert J.R. Heck | Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Exploring proteins within the coccolith matrix | Publication | 2024 | Craig J. Dedman, Nishant Chauhan, Alba González-Lanchas, Chloë Baldreki, Adam A. Dowle, Tony R. Larson, Renee B. Y. Lee & Rosalind E. M. Rickaby | Department of Earth Sciences, University of Oxford, South Parks Rd, Oxford, UK | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota | Publication | 2024 | Ana Martínez Gascueña, Isabel García-Álvarez, Jon Ander Nieto-Garai, June Olazar-Intxausti, Bárbara Rodríguez-Colinas, Enrique Mann, José Luis Chiara, Francesc-Xabier Contreras, Marcelo E. Guerin, Beatriz Trastoy & Laura Alonso-Sáez | AZTI, Marine Research, Basque Research and Technology Alliance (BRTA), Sukarrieta, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine | Publication | 2024 | Julienne L. Carstens, Mehmet Akce, Cameron Herting, Olatunji B. Alese, Karina J. Yoon, Upender Manne, Manoj K. Bhasin, Gregory B. Lesinski, Vikas P. Sukhatme, Bassel F. El-Rayes | Department of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA | 60 SPD | Thermo Q Exactive Plus | 60-spd | thermo-q-exactive-plus | |
The characterization of outer membrane vesicles (OMVs) and their role in mediating antibiotic-resistance gene transfer through natural transformation in Riemerella anatipestifer | Publication | 2024 | Mengying Wang, Yizhou Yao, Yuhao Yang, Dekang Zhu, Mingshu Wang, Renyong Jia, Shun Chen, Xinxin Zhao, Qiao Yang , Ying Wu , Shaqiu Zhang, Juan Huang, Xumin Ou, Bin Tian, Di Sun, Ling Zhang, Yanling Yu, Yu He, Zhen Wu, Anchun Cheng, Mafeng Liu | Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China | 100 SPD | Bruker timsTOF Pro 2 | 100-spd | timstof-pro-2 | |
Impaired Cerebrospinal Fluid Lipoprotein-Mediated Cholesterol Delivery to Neurons in Alzheimer’s Disease | Publication | 2024 | Carla Borràs, Marina Canyelles, David Santos, Noemí Rotllan, Estefanía Núñez, Jesús Vázquez, Daniel Maspoch, Mary Cano-Sarabia, Maria Carmona-Iragui, Sònia Sirisi, Alberto Lleó, Juan Fortea, Daniel Alcolea, Francisco Blanco-Vaca, Joan Carles Escolà-Gil, | Hospital de la Santa Creu i Sant Pau, Barcelona, Spain | 15 SPD | Thermo Orbitrap Eclipse Tribid | 15-spd | thermo-orbitrap-eclipse-tribid | |
Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster | Publication | 2024 | Najla El Fissi, Florian A. Rosenberger, Kai Chang, Alissa Wilhalm, Tom Barton-Owen, Fynn M. Hansen, Zoe Golder, David Alsina, Anna Wedell, Matthias Mann, Patrick F. Chinnery, Christoph Freyer & Anna Wredenberg | Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Enhancing Digestibility and Intestinal Peptide Release of Pleurotus eryngii Protein: An Enzymatic Approach | Publication | 2024 | Dandan Wang, Meng Zhang, Jianing Wan, Haiquan Liu, Ying Wang, Ruiheng Yang, Yingying Wu, Dapeng Bao, Hongyu Chen, Gen Zou and Yong Zhao | College of Food Sciences and Technology, Shanghai Ocean University, Shanghai, China | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
5′ terminal nucleotide determines the immunogenicity of IVT RNAs | Publication | 2024 | Magdalena Wolczyk, Jacek Szymanski, Ivan Trus, Zara Naz, Tola Tame, Agnieszka Bolembach, Nila Roy Choudhury, Karolina Kasztelan, Juri Rappsilber, Andrzej Dziembowski, Gracjan Michlewski | International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland | 60 SPD | Bruker timsTOF Ultra | 60-spd | bruker-timstof-ultra | |
Extracellular vesicles from mesenchymal stem cells improve neuroinflammation and neurotransmission in hippocampus and cognitive impairment in rats with mild liver damage and minimal hepatic encephalopathy | Publication | 2024 | Gergana Mincheva, Victoria Moreno-Manzano, Vicente Felipo & Marta Llansola | Laboratory of Neurobiology, Centro de Investigación Príncipe Felipe, Valencia, Spain | 30 SPD | Bruker timsTOF fleX | 30-spd | bruker-timstof-flex | |
Extracellular Vesicle-Driven Crosstalk between Legume Plants and Rhizobia: The Peribacteroid Space of Symbiosomes as a Protein Trafficking Interface | Publication | 2024 | Paula Ayala-García, Irene Herrero-Gómez, Irene Jiménez-Guerrero, Viktoria Otto, Natalia Moreno-de Castro, Mathias MüskenLothar Jänsch, Marco van Ham, José-María Vinardell, Francisco Javier López-Baena, Francisco Javier Ollero, Francisco Pérez-Montaño, Jos | Department of Microbiology, Faculty of Biology, Universidad de Sevilla, Sevilla, Spain | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
CCDC134 controls TLR biogenesis through the ER chaperone Gp96 | Publication | 2024 | Léa Bernaleau, Michaela Drobek, Fenja Blank, Philipp Walch, Maeva Delacrétaz, Ales Drobek, Marta Monguió-Tortajada, Petr Broz, Olivia Majer, Manuele Rebsamen | Department of Immunobiology, University of Lausanne, Epalinges, Switzerland | 15 SPD | Bruker timsTOF Pro | 15-spd | bruker-timstof-pro | |
The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base | Publication | 2024 | Sini Huuskonen, Xiaonan Liu, Ina Pöhner, Taras Redchuk, Kari Salokas, Rickard Lundberg, Sari Maljanen, Milja Belik, Arttu Reinholm, Pekka Kolehmainen, Antti Tuhkala, Garima Tripathi, Pia Laine, Sergei Belanov, Petri Auvinen, Maria Vartiainen, Salla Keskit | Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities | Publication | 2024 | Lydia Ziane-Chaouche, Antonella Raffo-Romero, Nawale Hajjaji, Firas Kobeissy, Donna Pinheiro, Soulaimane Aboulouard, Adeline Cozzani, Suman Mitra, Isabelle Fournier, Dasa Cizkova, Michel Salzet & Marie Duhamel | Université Lille, Inserm, CHU Lille, U1192, Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), Villeneuve d’Ascq, France | 60 SPD | Bruker timsTOF HT, Thermo Q Exactive | 60-spd | bruker-timstof-ht thermo-q-exactive | |
Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD | Publication | 2024 | Marcos Fernández-Alfara, Judit Martín, Cesare De Pace, Lorena Ruiz-Pérez, Jesús García, Giuseppe Battaglia, José J. Lucas, Rubén Hervás, Kresten Lindorff-Larsen, Raúl Méndez & Xavier Salvatella | Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain | Extended method | Thermo Orbitrap Eclipse Tribid | extended-method | thermo-orbitrap-eclipse-tribid | |
CRISPR/Cas9-induced double-strand breaks in the huntingtin locus lead to CAG repeat contraction through DNA end resection and homology-mediated repair | Publication | 2024 | Pawel Sledzinski, Mateusz Nowaczyk, Marianna Iga Smielowska & Marta Olejniczak | Department of Genome Engineering, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
Isobaric labeling update in MaxQuant | Publication | 2024 | Daniela Ferretti, Pelagia Kyriakido, Jinqiu Xiao, Shamil Urazbakhtin, Carlo DeNart and Jürgen Cox | Computational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Martinsried, Germany. | 30 SPD | Thermo Orbitrap Exploris 480, Thermo Orbitrap Fusion Tribid | 30-spd | thermo-orbitrap-exploris-480 thermo-orbitrap-fusion-tribid | |
Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport | Publication | 2024 | D. Bizzarri, E.B. van den Akker, M.J.T. Reinders, R. Pool, M. Beekman, N. Lakenberg, N. Drouin, K.E. Stecker, A.J.R. Heck, E.F. Knol, J.M. Vergeer, M.A. Ikram, M. Ghanbari, A.J. van Gool11, BBMRI-NL, D.I. Boomsma, and P.E. Slagboom | Department of Biomedical Data Sciences, Molecular Epidemiology, LUMC, Leiden, The Netherlands | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction | Publication | 2024 | Dragana Vukić, Anna Cherian, Salla Keskitalo, Yih Tyng Bong, Martin Marônek, Leena Yadav, Liam P Keegan, Markku Varjosalo, Mary A O’Connell | Central European Institute of Technology (CEITEC), Masaryk University, Kamenice 5, Brno, Czechia | Bruker timsTOF Pro, Thermo Orbitrap Fusion Lumos | bruker-timstof-pro thermo-orbitrap-fusion-lumos | |||
Nuclear Factor I family members are key transcription factors regulating gene expression | Publication | 2024 | Dicle Malaymar Pinar, Helka Göös, Zenglai Tan, Esa-Pekka Kumpula, Iftekhar Chowdhury, Zixian Wang, Qin Zhang, Kari Salokas, Salla Keskitalo, Gong-Hong Wei, Asli Kumbasar, Markku Varjosalo | Institute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Chemogenomic Screeningina Patient-Derived 3DFatty Liver Disease Model Reveals the CHRM1-TRPM8 Axisasa Novel Module for Targeted Intervention | Publication | 2024 | Brinton Seashore-Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, and Volker M. Lauschke | HepaPredict AB, Stockholm, Sweden | Whisper 20 SPD | Bruker timsTOF Pro 2 | whisper-20spd | timstof-pro-2 | |
Raphe and ventrolateral medulla proteomics in sudden unexplained death in childhood with febrile seizure history | Publication | 2024 | Dominique F. Leitner, Christopher William, Arline Faustin, Evgeny Kanshin, Matija Snuderl, Declan McGuone, Thomas Wisniewski, Beatrix Ueberheide, Laura Gould & Orrin Devinsky | Comprehensive Epilepsy Center, NYU Grossman School of Medicine, New York, NY, USA | Extended method | Thermo Q Exactive HF-X | extended-method | thermo-q-exactive-hf-x | |
Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation | Publication | 2024 | Legros Véronique, Albanese Véronique, Chevreux Guillaume, Camadro Jean-Michel & Auchère Françoise | Université Paris Cité, CNRS, Institut Jacques Monod, Paris, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
A novel process for transcellular hemoglobin transport from macrophages to cancer cells | Publication | 2024 | Jaroslaw Walczak, Lukasz Cheda, Michal Komorowski, Tobias Weiss, Małgorzata Czystowska-Kuzmicz, Karina Kwapiszewska, Alberto Boffi, Magdalena Krol & Tomasz P. Rygiel | Department of Immunology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB | Publication | 2024 | Benjamin E. Clarke, Oliver J. Ziff, Giulia Tyzack, Marija Petrić Howe, Yiran Wang, Pierre Klein, Claudia A. Smith, Cameron A. Hall, Adel Helmy, Michael Howell, Gavin Kelly & Rickie Patani | Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, UK | 30 SPD | Thermo Orbitrap Fusion | 30-spd | thermo-orbitrap-fusion | |
Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer | Publication | 2024 | Adva Kochavi, Remco Nagel, Pierre-Rene Körner, Onno B Bleijerveld, Chun-Pu Lin, Zowi Huinen, Yuval Malka, Natalie Proost, Marieke van de Ven, Xiaodong Feng, Jasmine Montenegro Navarro, Abhijeet Pataskar, Daniel S Peeper, Julien Champagne, Reuven Agami | Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
A Recombinant Shigella flexneri Strain Expressing ETEC Heat-Labile Enterotoxin B Subunit Shows Promise for Vaccine Development via OMVs | Publication | 2024 | Josune Salvador-Erro, Yadira Pastor, and Carlos Gamazo | Department of Microbiology and Parasitology, Navarra Medical Research Institute (IdiSNA), University of Navarra, Pamplona, Spain | Whisper100 20 SPD | Thermo Orbitrap Exploris 480 | whisper100-20-spd | thermo-orbitrap-exploris-480 | |
Porin expression in clinical isolates of Klebsiella pneumoniae: a comparison of SDS-PAGE and MALDI-TOF/MS and limitations of whole genome sequencing analysis | Publication | 2024 | Cristina Elías-López, Montserrat Muñoz-Rosa, Julia Guzmán-Puche, Elena Pérez-Nadales, Eduardo Chicano-Galvez & Luis Martínez-Martínez | Reina Sofía University Hospital, Maimonides Biomedical Research Institute of Cordoba, University of Cordoba (IMIBIC/HURS/UCO), Cordoba, Spain | Bruker timsTOF fleX | bruker-timstof-flex | |||
The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium | Publication | 2024 | Olivia Charmant, Julita Gruchota, Olivier Arnaiz, Katarzyna P Nowak, Nicolas Moisan, Coralie Zangarelli, Mireille Bétermier, Anna Anielska-Mazur, Véronique Legros, Guillaume Chevreux, Jacek K Nowak, Sandra Duharcourt | Université Paris Cité, CNRS, Institut Jacques Monod, Paris, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
A compendium of bona fide reference markers of plant-derived extracellular vesicles and their degree of phylogenetic conservation | Publication | 2024 | Rodríguez de Lope, Miriam M. Sánchez-Pajares, Ibone R. Herranz, Estela López Vázquez, Cristina M. González-Moro, Ainara Rivera-Tenorio, Alan González-Sanz Carlos, Soledad Sacristán, Chicano-Gálvez, Eduardo de la Cuesta, Fernando | Department of Pharmacology, School of Medicine, Universidad Autónoma de Madrid, Spain | Extended method | Bruker timsTOF fleX | extended-method | bruker-timstof-flex | |
Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway which is dependent on low IGF1R level | Publication | 2024 | Sarah Hyllekvist Jørgensen, Kristina Bennet Emdal, Anna-Kathrine Pedersen, Lene Nygaard Axelsen, Helene Faustrup Kildegaard, Damien Demozay, Thomas Åskov Pedersen, Mads Grønborg, Rita Slaaby, Peter Kresten Nielsen & Jesper Velgaard Olsen | Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Optimization of a Digestion Protocol for Proteomic Profiling of Low Cell Number FACS-Sorted Cells | Publication | 2024 | Kovi Rishya Shrung Govindarajan | KTH Royal Institute of Technology, Stockholm, Sweden | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training | Publication | 2024 | Juha J. Hulmi, Eeli J. Halonen, Adam P. Sharples, Thomas M. O'Connell, Lauri Kuikka L, VeliMatti Lappi, Kari Salokas, Salla Keskitalo, Markku Varjosalo, Juha P. Ahtiainen | Faculty of Sport and Health Sciences, Neuromuscular Research Center, University of Jyväskylä,Finland | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Data-independent acquisition-based blood proteomics unveils predictive biomarkers for neonatal necrotizing enterocolitis | Publication | 2024 | Feng Chen, Kezhe Tan, Zhibao Lv, Faling Chen, Weijue Xu, Xiaohui Gong, Li Lu, Hailiang Sun, Qinqin Fu & Wenjun Zhuang | Department of General Surgery, Affiliated Changzhou Children’s Hospital of Nantong University, Jiangsu, China | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease | Publication | 2024 | Sumi Bez, Elena Ficulle, Eliona Tsefou, Roman Fischer, Beth Geary, Pallavi Gaur, Chelsea Miller, Pasquale D’Acunzo, Efrat Levy, Karen E. Duff & Benjamin Ryskeldi-Falcon | Medical Research Council Laboratory of Molecular Biology, Cambridge, UK | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model | Publication | 2024 | Neža Cankar, Natalie Beschorner, Anastasia Tsopanidou, Filippa L. Qvist, Ana R. Colaço, Mie Andersen, Celia Kjaerby∙ Christine Delle, Marius Lambert, Filip Mundt, Pia Weikop, Mathias Jucker, Matthias Mann, Niels Henning Skotte, Maiken Nedergaard | Center for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen N, Denmark | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Identification and Characterization of Spontaneous AA Amyloidosis in CD-1 Mice Used in Toxicity | Publication | 2024 | Mao Mizukawa, Kohei Tanaka, Akane Kashimura, Yu Uchida, Takanori Shiga, Naoyuki Aihara, and Junichi Kamie | Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa, Japan | 30 SPD | Thermo Q Exactive | 30-spd | thermo-q-exactive | |
Anubis: a multi-level authentication scale for ancient proteins using random forest classification | Publication | 2024 | Yun Chiang, Bharath Anila Bhuvanendran Nair, Max Emil Ermter Ramsøe, Tina Ravnsborg, Ole Nørregaard Jensen & Matthew James Collins | Globe Institute, University of Copenhagen, Copenhagen, Denmark | 60 SPD | Thermo Q Exactive HF | 60-spd | thermo-q-exactive-hf | |
Towards routine proteome profiling of FFPE tissue: insights from a 1,220-case pan-cancer study | Publication | 2024 | Johanna Tüshaus, Marius Schliemann, Yuxiang Zhou, Pauline Pfeiffer, Christiane Halves, Federico Fusco, Johannes Weigel, Lisa Hönikl, Vicki Butenschön, Rumyana Todorova, Hilka Rauert-Wunderlich, Matthew The, Andreas Rosenwald, Volker Heinemann, Julian Holc | Proteomics and Bioanalytics, School of Life SciencesTechnical University of Munich Freising Germany | 100 SPD | Thermo Orbitrap Exploris 480 | 100-spd | thermo-orbitrap-exploris-480 | |
Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases | Publication | 2024 | Maria Chernigovskaya, Khang Lê Quý, Maria Stensland, Sachin Singh, Rowan Nelson, Melih Yilmaz, Konstantinos Kalogeropoulos, Pavel Sinitcyn, Anand Pate, Natalie Castellana, Stefano Bonissone, Stian Foss, Jan Terje Andersen, Geir Kjetil Sandve, Timothy Patr | Department of Immunology, University of Oslo and Oslo University Hospital, Norway | 20 SPD | Thermo Q Exactive HF | 20-spd | thermo-q-exactive-hf | |
High-Throughput Tear Proteomics via In-Capillary Digestion for Biomarker Discovery | Publication | 2024 | James Xiao, Kyla Frenia, Kathleen C. Garwood,Jeremy Kimmel and Leanne T. Labriola | Retina Department, Sewickley Eye Group, Sewickley, PA, USA | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Mass spectrometry–based proteomic exploration of diverse murine macrophage cellular models | Publication | 2024 | Jack Gudgeon, Abeer Dannoura, Ritika Chatterjee, Frances Sidgwick, Benjamin BA Raymond, Andrew M Frey, Jose Luis Marin-Rubio, Matthias Trost | Newcastle University: Newcastle upon Tyne, Newcastle upon Tyne, GB | Whisper 20 SPD | Thermo Q Exactive HF | whisper-20spd | thermo-q-exactive-hf | |
Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification | Publication | 2024 | Mujia Jenny Li, Larissa Chiara Meyer, Nadine Meier, Jannik Witte, Maximilian Maldacker, Adrianna Seredynska, Julia Schueler, Oliver Schilling, Melanie Christine Föll | Institute for Surgical Pathology, Faculty of Medicine, University Medical Centre Freiburg, University of Freiburg, Freiburg, Germany | 30 SPD | Bruker timsTOF fleX | 30-spd | bruker-timstof-flex | |
Characterization of psychrotrophic and thermoduric bacteria in raw milk using a multi-omics approach | Publication | 2024 | Xue Qin, Jingqi Cheng, Yue Qiu, Ning Guan, Tanushree B. Gupta, Shuyan Wu, Yujun Jiang, Xinyan Yang and Chaoxin Man | Key Laboratory of Dairy Science, Ministry of Education, College of Food Science and Engineering, Northeast Agricultural University, Harbin, PR China | Bruker timsTOF | bruker-timstof | |||
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5 | Publication | 2024 | Joan Josep Bech, Thomas Braun, Alessandro Ianni, Jay A. Tischfield, Lourdes Serrano, Manel Esteller, Jose L. Sardina, Carolina De La Torre, Mikael Sigvardsson, Berta N. Vazquez & Alejandro Vaquero | Chromatin Biology Laboratory, Josep Carreras Leukemia Research Institute, Badalona, Spain | 15 SPD | 15-spd | |||
The MON1–CCZ1 complex plays dual roles in autophagic degradation and vacuolar protein transport in rice | Publication | 2024 | Yongfei Wang, Pengcheng Zhang, Yu Chen, Erchao Duan, Xiaohang Han, Gexing Wan, Mengyuan Yan, Xiejun Sun, Cailin Lei, Zhijun Cheng, Zhichao Zhao, Ling Jiang, Yiqun Bao, Yulong Ren and Jianmin Wan | State Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China | Bruker timsTOF Pro | bruker-timstof-pro | |||
B-246 Pab to mab conversion via mass spectrometry: direct antibody discovery from serum | Publication | 2024 | J Crha, X Han, T Le Bihan, T Nunez De Villavicencio Diaz, B Ma | Rapid Novor, Inc., Kitchener, ON, Canada | Thermo Orbitrap Eclipse | thermo-orbitrap-eclipse | |||
HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status | Publication | 2024 | Marc E. Healy, Amiskwia Pöschel, Enni Markkanen, Nasser Semmo, Martin Ferrié, Laurence Cocquerel, Harald Seeger, Helmut Hopfer, Beat Müllhaupt, Jérôme Gouttenoire, Darius Moradpour, Ariana Gaspert & Achim Weber | Department of Pathology and Molecular Pathology, University of Zurich (UZH) and University Hospital Zurich (USZ), Zurich, Switzerland | Bruker timsTOF Pro, Thermo Orbitrap Astral | bruker-timstof-pro thermo-orbitrap-astral | |||
Proteomic and metabolomic profiles of plasma-derived Extracellular Vesicles differentiate melanoma patients from healthy controls | Publication | 2024 | SM Bollard, J Howard, C Casalou, BS Kelly, K O’Donnell, G Fenn, J O’Reilly, R Milling, M Shields, M Wilson, A Ajaykumar, K Triana, K Wynne, DJ Tobin, PA Kelly,A McCann, SM Potter | Department of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin, Ireland | Bruker timsTOF Pro | bruker-timstof-pro | |||
Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis | Publication | 2024 | Daniel Stephenson, Marta Suarez Cubero, Sandra Rizzi, Liviu Pirvan, Luca Peruzzotti-Jametti, Valentina Fossati, Frank Edenhofer, Tommaso Leonardi, Christian Frezza, Irina Mohorianu, Angelo D’Alessandro, Stefano Pluchino | Department of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge CB2 0AH, UK | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Robust high throughput peptide quantitation using scout triggered MRM on the Triple Quad 7500 system | Publication | 2024 | J.C. Yves Le Blanc, Jenny Albanese, Holly Lee, David M. Cox, and Patrick Pribil | SCIEX Canada | 100 SPD, 200 SPD, 300 SPD, 500 SPD, 60 SPD | SCIEX QTRAP 7500 | 100-spd 200-spd 300-spd 500-spd 60-spd | sciex-triple-quad-7500 | |
Small molecule modulation of protein corona for deep plasma proteome profiling | Publication | 2024 | Ghafar Yerima, Ali Tamadon, Maryam Sayadi, Maryam Jafari, Zijin Lin, Danilo Ritz, David Kakhniashvili, Avirup Guha, Mohammad R. K. Mofrad, Liangliang Sun, Markita P. Landry, Amir Ata Saei & Morteza Mahmoudi | Precision Health Program, Michigan State University, East Lansing, MI, USA | 30 SPD | Thermo Orbitrap Astral | 30-spd | thermo-orbitrap-astral | |
Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint | Publication | 2024 | Daniel Blears, Jiangman Lou, Nova Fong, Richard Mitter, Ryan M. Sheridan, Dandan He, A. Barbara Dirac-Svejstrup, David Bentley, Jesper Q. Svejstrup | Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, Copenhagen, Denmark | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
High throughput single-cell proteomics of in-vivo cells | Publication | 2024 | Shiri Karagach, Joachim Smollich, Ofir Atrakchi, Vishnu Mohan, and Tamar Geiger | Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel | Whisper Zoom 40 SPD | Bruker timsTOF SCP | whisper-zoom-40-spd | bruker-timstof-scp | |
Single-Cell Proteomic and Transcriptomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes | Publication | 2024 | Jongmin Woo, Michael Loycano, Md Amanullah, Jiang Qian, Sarah Amend, Kenneth Pienta, Hui Zhang | Cancer Ecology Center, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231 | 100 SPD | Bruker timsTOF HT | 100-spd | bruker-timstof-ht | |
From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism | Publication | 2024 | Ivan Bradić, Katharina B. Kuentzel, Anita Pirchheim, Silvia Rainer, Birgit Schwarz, Michael Trauner, Martin R. Larsen, Nemanja Vujić, Dagmar Kratky | Gottfried Schatz Research Center, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
The proteomic landscape of proteotoxic stress in a fibrogenic liver disease | Publication | 2024 | Maximilian Zwiebel, Niklas A. Schmacke, Sonke Detlefsen, Peter Boor, Joseph Kaserman, Andrew Wilson, Ondrej Fabian, Sona Frankova, Aleksander A. Krag, Pavel Strnad, and Matthias Mann | Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | Whisper Zoom 40 SPD | Thermo Orbitrap Astral | whisper-zoom-40-spd | thermo-orbitrap-astral | |
High-Throughput Chromatography for Clinical Proteomics Applications | Publication | 2024 | Goran Mitulović and Jadranka Miletić Vukajlović | Bruker Austria, Vienna, Austria | 100 SPD | Bruker timsTOF Pro | 100-spd | bruker-timstof-pro | |
Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise | Publication | 2024 | Birgitte Hoier, Camilla C. Hansen, Thomas E. Jensen, Ylva Hellsten, Henriette Pilegaard, Niels Grarup, Jesper Olesen, Sean J. Humphrey, David E. James, Michael L. Pedersen, Erik A. Richter, Torben Hansen, Marit E. Jørgensen & Jørgen F. P. Wojtaszewski | August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Characterization of the Peroxisomal Proteome and Redox Balance in Human Prostate Cancer Cell Lines | Publication | 2024 | Mohamed A. F. Hussein, Celien Lismont, Cláudio F. Costa, Hongli Li,Frank Claessens and Marc Fransen | Laboratory of Peroxisome Biology and Intracellular Communication, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium | 30 SPD | SCIEX ZenoTOF 7600 | 30-spd | sciex-zenotof-7600 | |
Developing a Soft Micropatterned Substrate to Enhance Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes | Publication | 2024 | Yasaman Maaref, Shayan Jannati, Farah Jayousi, Philipp Lange, Mohsen Akbari, Mu Chiao, Glen F Tibbits | Cellular and Regenerative Medicine Centre, BC Children's Hospital Research Institute, Vancouver, BC, Canada | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Combining ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma | Publication | 2024 | Marco Scarsella, Gabriele Volpe, Marco Pezzullo, Cristiano De Stefanis, Valentina D’Oria, Lorenzo De Angelis, Roberto Giovannoni, Maria Antonietta De Ioris, Ombretta Melaiu, Anthony W. Purcell, Franco Locatelli & Doriana Fruci | Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy | Whisper Zoom 20 SPD | Bruker timsTOF Pro 2 | whisper-zoom-20-spd | timstof-pro-2 | |
Using in vivo intact structure for system-wide quantitative analysis of changes in proteins | Publication | 2024 | Ahrum Son, Hyunsoo Kim, Jolene K. Diedrich, Casimir Bamberger, Daniel B. McClatchy, Stuart A. Lipton & John R. Yates III | Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Effect of ultrasound and enzymatic pre-treatments on the profile of bioactive peptides of beef liver hydrolysates | Publication | 2024 | Marta Gallego, Leticia Mora, Fidel Toldrá | Instituto de Agroquímica y Tecnología de Alimentos (CSIC), Paterna, Valencia, Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Cytoprotective Effects of Antioxidant Peptides from Red Californian Worm (Eisenia foetida) Hydrolysate on Differentiated Caco-2 Cells | Publication | 2024 | Yhoan S. Gaviria, José E. Zapata, Diego Miedes, Amparo Alegría and Antonio Cilla | Nutrition and Food Science Area, Faculty of Pharmacy and Food Sciences, University of Valencia, Avda. Vicente Andrés Estellés s/n, Burjassot, Valencia, Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Integrative phosphoproteomic analysis reveal hemostatic-endothelial signaling interplay Integrative phosphoproteomic analysis reveal hemostatic-endothelial signaling interplay | Publication | 2024 | Stijn A. Groten, Bart L. van den Eshof, Floris P.J. van Alphen, Alexander B. Meijer, Maartje van den Biggelaar , Arie J. Hoogendijk | Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands | Whisper 20 SPD | Bruker timsTOF HT | whisper-20spd | bruker-timstof-ht | |
High-throughput and high-sensitivity biomarker monitoring in body fluid by fast LC SureQuant™ IS targeted quantitation | Publication | 2024 | Konstantinos Kalogeropoulos, Simonas Savickas, Aleksander M. Haack, Cathrine A. Larsen, Jacek Mikosiński, Erwin M. Schoof, Hans Smola, Louise Bundgaard, Ulrich auf dem Keller | Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Kgs. Lyngby, Denmark | 100 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 100-spd 60-spd | thermo-orbitrap-exploris-480 | |
P-stalk ribosomes act as master regulators of cytokine-mediated processes | Publication | 2024 | Mandy Kerkhoff, Anastasia Gangaev, Joana Silva, Sofia Ramalho, Liesbeth Hoekman, Maarten Altelaar, Roderick Beijersbergen, Leila Akkari, Jonathan Wilson Yewdel, Pia Kvistborg, William James Faller | Division of Oncogenomics, Netherlands Cancer Institute, Amsterdam, the Netherlands | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
Proteomics dataset of lysolecithin-induced demyelinated lesions in corpus callosum of Lewis rats, treated with Vagus Nerve Stimulation or sham treatment | Publication | 2024 | Helen Bachmann, Boris Vandemoortele, Vanessa Vermeirssen, Evelien Carrette, Kristl Vonck, Paul Boon, Robrecht Raedt, Guy Laureys | 4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, Ghent, Belgium | Whisper 20 SPD | Bruker timsTOF SCP | whisper-20spd | bruker-timstof-scp | |
Unveiling the critical role of androgen receptor signaling in avian sexual development | Publication | 2024 | Kamila Lengyel, Mekhla Rudra, Tom V. L. Berghof, Albertine Leitão, Carolina Frankl-Vilches, Falk Dittrich, Denise Duda, Romina Klinger, Sabrina Schleibinger, Hicham Sid, Lisa Trost, Hanna Vikkula, Benjamin Schusser & Manfred Gahr | Department of Behavioural Neurobiology, Max Planck Institute for Biological Intelligence, Seewiesen, Germany | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Streamlined analysis of drug targets by proteome integral solubility alteration indicates organ-specific engagement | Publication | 2024 | Tanveer Singh Batth, Marie Locard-Paulet, Nadezhda T. Doncheva, Blanca Lopez Mendez, Lars Juhl Jensen & Jesper Velgaard Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Thermo Orbitrap Exploris 480, Thermo Q Exactive HF-X | 30-spd | thermo-orbitrap-exploris-480 thermo-q-exactive-hf-x | |
Spatial proteomics identifies JAKi as treatment for a lethal skin disease | Publication | 2024 | Florian Anzengruber, Maximilian T. Strauss, Maria C. Tanzer, Yuki Saito, Ting Gong, Marvin Thielert, Haruna Kimura, Natasha Silke, Edwin H. Rodriguez, Gaetana Restivo, Hong Ha Nguyen, Annette Gross, Laurence Feldmeyer, Matthias Mann | Department of Proteomics and Signal Transduction; Max Planck Institute of Biochemistry, Martinsried, Germany | Whisper 40 SPD | Thermo Orbitrap Astral | whisper-40spd | thermo-orbitrap-astral | |
Rivaroxaban in combination with low-dose aspirin is associated with a reduction in pro-inflammatory and pro-thrombotic circulating vesicle signatures in patients with cardiovascular disease | Publication | 2024 | Luisa Weiss, Aideen O’Doherty, Wido Uhrig, Paulina B. Szklanna, Molly Hong-Minh, Kieran Wynne, Alfonso Blanco, Jan Zivny, Valeria Lima Passos, Barry Kevane, Seán Murphy, Fionnuala Ní Áinle, Martin O’Donnell, Patricia B. Maguire | UCD Conway SPHERE Research Group, Conway Institute, University College Dublin, Dublin, Ireland | Extended method | Bruker timsTOF Pro | extended-method | bruker-timstof-pro | |
Longitudinal Assessment of Nasopharyngeal Biomarkers Post-COVID-19: Unveiling Persistent Markers and Severity Correlations | Publication | 2024 | Mario Durán-Prado, Soledad Illescas, Eduardo Chicano-Galvez, Francisco Javier Gómez-Romero, José Martinez-Alarcón, Javier Arias-Pardilla, Pilar Lopez-Juarez, Juan Fernando Padin, Juan Ramón Peinado, Leticia Serrano-Oviedo | Traslational Investigation Unit, University General Hospital, SESCAM. Research Institute of Castilla-La Mancha (IDISCAM), Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Probing SARS-CoV-2 Spike Protein Receptor Binding Domain Dynamics via Hydroxyl Radical Protein Footprinting | Publication | 2024 | Kezia M. Jemison | University of California San Diego | 30 SPD | Thermo Orbitrap Astral | 30-spd | thermo-orbitrap-astral | |
A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastoma | Publication | 2024 | Stephanie Maher, Kieran Wynne, Vadim Zhernovkov & Melinda Halasz | Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Annulate Lamellae biogenesis is essential for nuclear pore function | Publication | 2024 | Junyan Lin, Arantxa Agote-Arán, Yongrong Liao, Rafael Schoch, Paolo Ronchi, Victor Cochard, Rui Zhu, Charlotte Kleiss, Marc Ruff, GuillaumeChevreux, Yannick Schwab, Bruno P. Klaholz and Izabela Sumara | Institute of Genetics and Molecular and Cellular Biology (IGBMC), Illkirch, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage | Publication | 2024 | James Barrett, Mihris I. S. Naduthodi, Yuwei Mao, Clément Dégut, Sabina Musiał, Aidan Salter, Mark C. Leake, Michael J. Plevin, Alistair J. McCormick, James N. Blaza & Luke C. M. Mackinder | Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Rapid Tear Proteomics via In-Capillary Digestion for Biomarker Discovery | Publication | 2024 | James Xiao , Kyla T Frenia , Kathleen C Garwood , Jeremy Kimmel , Leanne T Labriola | Retina Department, Sewickley Eye Group, Sewickley, PA, USA | 60 SPD, Extended method | Bruker timsTOF Pro 2 | 60-spd extended-method | timstof-pro-2 | |
Optimizing proximity proteomics on the EvoSep-timsTOF LC-MS system | Publication | 2024 | Julia Kitaygorodsky, Brendon Seale, Reuben Samson, Martina Tersigni, Zhen-Yuan Lin, Cassandra Wong, Vesal Kasmaeifar, Anne-Claude Gingras | Lunenfeld-Tanenbaum Research Institute | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Daphnia stress response to environmental concentrations of chloramphenicol—multi-omics approach | Publication | 2024 | Malgorzata Grzesiuk, Marta Grabska, Agata Malinowska, Bianka Świderska, Elzbieta Grzesiuk, Damian Garbicz & Adrian Gorecki | Department of Biochemistry and Microbiology, Institute of Biology; Warsaw, University of Life Sciences (SGGW), Warsaw, Poland | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N labeled proteins | Publication | 2024 | Maria Wahle, Philip M. Remes, Vincent Albrecht, Johannes Mueller-Reif, Sophia Steigerwald,Tim Heymann, Lili Niu, Philip Lössl, Stevan Horning, Cristina C. Jacob, Matthias Mann | Department for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
1 Annulate Lamellae biogenesis is essential for nuclear pore function | Publication | 2024 | Junyan Lin, Arantxa Agote-Arán, Yongrong Liao, Rafael Schoch, Paolo Ronchi, Victor Cochard, Rui Zhu, Charlotte Kleiss1,2,3,4, Marc Ruff1,2,3,4,6 3 , Guillaume Chevreux, Yannick Schwab, Bruno P. Klaholz and Izabela Sumara | Institute of Genetics and Molecular and Cellular Biology (IGBMC), Illkirch, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Deep Proteome Analysis of Cerebrospinal Fluid from Pediatric Patients with Central Nervous System Cancer | Publication | 2024 | Christian Mirian, Ole Østergaard, Maria Thastrup, Signe Modvig, Jon Foss-Skiftesvik ,Jane Skjøth-Rasmussen, Marianne Berntsen, Josefine Britze, Alex Christian Yde Nielsen, René Mathiasen, Kjeld Schmiegelow, Jesper Velgaard Olsen | Novo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | 100 SPD, 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 100-spd 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
De novo protein sequencing of antibodies for identification of neutralizing antibodies in human plasma post SARS-CoV-2 vaccination | Publication | 2024 | Thierry Le Bihan, Teresa Nunez de Villavicencio Diaz, Chelsea Reitzel, Victoria Lange, Minyoung Park, Emma Beadle, Lin Wu, Marko Jovic, Rosalin M. Dubois, Amber L. Couzens, Jin Duan, Xiaobing Han, Qixin Liu & Bin Ma | Rapid Novor, Inc., Kitchener, ON, Canada | 30 SPD | Thermo Orbitrap Eclipse Tribid, Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-eclipse-tribid thermo-orbitrap-exploris-480 | |
A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastoma | Publication | 2024 | Stephanie Maher, Kieran Wynne, Vadim Zhernovkov & Melinda Halasz | Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors | Publication | 2024 | Haiyan Wang,Paul Westwood, Andreas Topp, Patricia M. Gomez Barila, Jan Paul Medema, Connie R. Jimenez, Bigna Woersdoerfer,3 Stephan Kirchner,3 8 Jitao, David Zhang, Uwe Grether, Arne C. Rufer, Mario van der Stelt | Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, Leiden, Netherlands | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Exercise-Induced Proteomic Profile Changes in Patients with Advanced Heart Failure | Publication | 2024 | Anna Drohomirecka,Joanna Waś, Ewa Sitkiewicz, Bianka Świderska, Anna Lutyńska, Tomasz Rywik and Tomasz Zieliński | Department of Heart Failure and Transplantation, National Institute of Cardiology, Warsaw, Poland | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Automated High-Throughput Biological Sex Identification from Archeological Human Dental Enamel Using Targeted Proteomics | Publication | 2024 | Gaudry B. Troché, Nuno Vibe Hermann, Marina Martínez de Pinillos, María Martinón-Torres, Sandra Mularczyk, Marie Louise Schjellerup Jørkov, Christopher Gerner, Fabian Kanz, Ana Martinez-Val, Enrico Cappellini , Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences , 4321 University of Copenhagen, Denmark | 200 SPD | Thermo Orbitrap Exploris 480 | 200-spd | thermo-orbitrap-exploris-480 | |
Chlorin e6-Loaded Nanostructured Lipid Carriers Targeted by Angiopep-2: Advancing Photodynamic Therapy in Glioblastoma | Publication | 2024 | Carlotta Pucci, Daniele De Pasquale, Andrea Degl'Innocenti, Margherita Montorsi, Andrea Desii, Marta Pero, Chiara Martinelli, Martina Bartolucci, Andrea Petretto, Gianni Ciofani | Istituto Italiano di Tecnologia, Smart Bio-Interfaces, Viale Rinaldo Piaggio 34, Pontedera, Italy | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis | Publication | 2024 | Viktória Szentgyörgyi, Leon Maximilian Lueck, Daan Overwijn , Danilo Ritz, Nadja Zoeller , Alexander Schmidt, Maria Hondele , Anne Spang , Shahrzad Bakhtiar | Biozentrum, University of Basel, Basel, Switzerland | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Multi-Omics Revealed Regulatory Mechanisms Underlying the Flowering of Ferula sinkiangensis across Three Dimensions | Publication | 2024 | Congzhao Fan, Yanfei Li, Jizhao Zhang, Yaqin Zhao, Yigong Zhang, Jun Zhu, Xingwang Gao, Yan Liang, Yuanjin Qiu, Jingyuan Song, and Guoping Wang | Key Laboratory of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People’s Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube | Publication | 2024 | Joanna Bons, Isha Bhorkar, Triya Roy, David Schell, Vasco Queiroga, Kehan Ren, Donald Kramer, Wilson Huang, Gabriella C. Russo, Meng-Horng Lee, Pei-Hsun Wu, Ie-Ming Shih, Tian-Li Wang, Mark A. Atkinson, Birgit Schilling, Ashley L. Kiemen, and Denis Wirtz | Johns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD, USA | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy | Publication | 2024 | Sharon Grisaru-Tal, Valentina Zemser-Werner, Ronen Brenner, Hananya Vaknine, Eran Nizri, Lilach Moyal, Iris Amitay-Laish, Luiza Rosemberg, Ariel Munitz, Noga Kronfeld-Schor, Eric Shifrut, Oren Kobiler, Asaf Madi, Tamar Geiger, Yaron Carmi & Carmit Levy | Department of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel | Whisper 40 SPD | Bruker timsTOF HT | whisper-40spd | bruker-timstof-ht | |
A Multiomics Evaluation of the Countermeasure Influence of 4-Week Cranberry Beverage Supplementation on Exercise-Induced Changes in Innate Immunity | Publication | 2024 | David C. Nieman, Camila A. Sakaguchi, James C. Williams, Jongmin Woo, Ashraf M. Omar, Fayaj A. Mulani, Qibin Zhang, Wimal Pathmasiri, Blake R. Rushing, Susan McRitchie, Susan J. Sumner, Jackie Lawson and Kevin C. Lambirth | Human Performance Laboratory, Appalachian State University, North Carolina Research Campus (NCRC), Kannapolis, NC, USA | 60 SPD | Thermo Orbitrap Exploris 240 | 60-spd | thermo-orbitrap-exploris-240 | |
mTOR activity paces human blastocyst stage developmental progression | Publication | 2024 | Maria Novatchkova, Afshan McCarthy, Teresa Rayon, Claire S. Simon, Ilona Dunkel, Sissy E. Wamaitha, Kay Elder, Phil Snell, Leila Christie, Edda G. Schulz, Kathy K. Niakan, Nicolas Rivron, Aydan Bulut-Karslioğlu | Stem Cell Chromatin Group, Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany | 30 SPD | Bruker timsTOF SCP | 30-spd | bruker-timstof-scp | |
Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity | Publication | 2024 | Yun Xiong, Lin Tan, Wai-kin Chan, Eric S. Yin, Sri Ramya Donepudi, Jibin Ding, Bo Wei, Bao Tran, Sara Martinez, Iqbal Mahmud, Hamish I. Stewart, Daniel J.Hermanson, John N. Weinstein, Philip L. Lorenzi | Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX, USA | 500 SPD | Bruker timsTOF Pro 2, Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | 500-spd | timstof-pro-2 thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
High resolution analysis of proteolytic substrate processing | Publication | 2024 | Jasmin Schillinger, Michelle Koci, Kenny Bravo-Rodriguez, Geronimo Heilmann, Farnusch Kaschani, Markus Kaiser, Christine Beuck, Hartmut Luecke, Robert Huber, Doris Hellerschmied, Steven G. Burston, Michael Ehrmann | Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany | 60 SPD | Thermo Orbitrap Fusion Lumos | 60-spd | thermo-orbitrap-fusion-lumos | |
Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training | Publication | 2024 | Lukas Moesgaard, Roger Moreno-Justicia, Johann Schmalbruch, Søren Jessen, Ben Stocks, Jens Bangsbo, Atul S. Deshmukh, Morten Hostrup | The August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria | Publication | 2024 | Pablo Hernansanz-Agustín, Carmen Morales-Vidal, Enrique Calvo, Paolo Natale, Yolanda Martí-Mateos, Sara Natalia Jaroszewicz, José Luis Cabrera-Alarcón, Rebeca Acín-Pérez, Iván López-Montero, Jesús Vázquez, José Antonio Enríquez | Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain | 30 SPD | Thermo Orbitrap Ascend Tribid | 30-spd | thermo-orbitrap-ascend-tribid | |
Tandem mass tag-based proteomic analysis of granulosa and theca interna cells of the porcine ovarian follicle following in vitro treatment with vitamin D3 and insulin alone or in combination | Publication | 2024 | Kinga Kamińska, Bianka Świderska, Agata Malinowska, Małgorzata Grzesiak | Department of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
LETMD1 regulates mitochondrial protein synthesis and import to guard brown fat mitochondrial integrity and function | Publication | 2024 | Madigan Snyder, Yi-Kai Liu, Renjie Shang, Haowei Xu, Charlie Thrift, Xiyue Chen, Jingjuan Chen, Kun Ho Kim, Jiamin Qiu, Pengpeng Bi, W. Andy Tao, Shihuan Kuang | Department of Animal Sciences, Purdue University, West Lafayette, IN, USA | Whisper 40 SPD | Bruker timsTOF HT | whisper-40spd | bruker-timstof-ht | |
Optimization of Mass Spectrometry-Based Methods for Low-Input and Spatial Proteomics | Publication | 2024 | Andikan Jones Nwosu | Department of Chemistry and Biochemistry, Brigham Young University | 200 SPD | Thermo Orbitrap Astral | 200-spd | thermo-orbitrap-astral | |
Plasma proteomes of acute myeloid leukemia patients treated with transfusions reveal signatures of inflammation and hemostatic dysregulation | Publication | 2024 | Eva R. Smit, Diana Muñoz Sandoval, Iris C. Kreft, Pieter F. van der Meer, Carmen van der Zwaan, Jan Voorberg, Paula F. Ypma, Arie J. Hoogendijk, Jean-Louis Kerkhoffs & Maartje van den Biggelaar | Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands | 30 SPD | Thermo Orbitrap Lumos | 30-spd | thermo-orbitrap-lumos | |
Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage | Publication | 2024 | Tiangen Chang, Carmela Rubolino, Kathrin Laue, Yael Cohen-Sharir, Simone Scorzoni, Silvia Taglietti, Alice Ratti, Chani Stossel, Talia Golan, Francesco Nicassio, Eytan Ruppin, Markus Ralser, Francisca Vazquez, Uri Ben-David & Stefano Santaguida | Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Milan, Italy | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Rapid amelogenin sex estimation of human and cattle remains using untargeted Evosep-timsTOF mass spectrometry | Publication | 2024 | Charllotte Blacka, Adam Dowle, Mik Lisowski, Michelle Alexander, Jessica Hendy, Kirsty Penkman, Jackie Mosely | University of York Department of Chemistry | Whisper 20 SPD | Bruker timsTOF HT | whisper-20spd | bruker-timstof-ht | |
Exceeding 1000 cells per day – scalable single cell analysis using the Evosep Whisper Zoom method on the timsTOF Ultra 2 | e-Book | 2024 | Christoph Krisp, Dorte Bekker-Jensen, Ole Bjeld Hørning, Nicolai Bache, Torsten Müller, Markus Lubeck, Daniel Hornburg | Bruker Daltonics GmbH & Co. KG, Bremen, Germany | Whisper Zoom 120 SPD | Bruker timsTOF Ultra | whisper-zoom-120-spd | bruker-timstof-ultra | |
Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate | Publication | 2024 | Irina Nelepcu, Mona Marzban, Htoo Zarni Oo, Maj Sofie Ørum-Madsen, Yuzhuo Wang, Morten A. Nielsen, Henrik Clausen, Michael Wierer, Dominik Wolf, Ismail Gögenur, Thor G. Theander, Nader Al-Nakouzi, Tobias Gustavsson, Mads Daugaard & Ali Salanti | Centre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
A Multiomics Evaluation of theCountermeasure Influence of 4-Weeks Cranberry Beverage Supplementationon Exercise-Induced Changes in InnateImmunity | Publication | 2024 | David Christopher Nieman, Camila A Sakaguchi, James C Williams, Jongmin Woo, Ashraf M Omar,Fayaj A Mulani, Qibin Zhang, Wimal Pathmasiri, Blake R Rushing, Susan McRitchie, Susan J Sumner, Jackie Lawson, Kevin C Lambirth | Human Performance Laboratory, Appalachian State University, North Carolina Research Campus(NCRC), Kannapolis, NC, USA | 60 SPD | Thermo Orbitrap Exploris 240 | 60-spd | thermo-orbitrap-exploris-240 | |
Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells | Publication | 2024 | Thomas Sevrin, Hiroaki Imoto, Sarah Robertson, Nora Rauch, Uscinnia Dyn’ko, Katerina Koubova, Kieran Wynne, Walter Kolch, Oleksii S. Rukhlenko, Boris N. Kholodenko | Systems Biology Ireland, University College Dublin, Dublin, Ireland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Quantitation of Host Cell Proteins by Capillary LC/IMS/MS/MS in Combination with Rapid Digestion on Immobilized Trypsin Column Under Native Conditions | Publication | 2024 | Ryota Tomioka, Kosuke Ogata, and Yasushi Ishihama | Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Pseudouridine guides germline small RNA transport and epigenetic inheritance | Publication | 2024 | Rowan P. Herridge, Jakub Dolata, Valentina Migliori, Cristiane de Santis Alves, Filipe Borges, Andrea J. Schorn, Frédéric van Ex, Ann Lin, Mateusz Bajczyk, Jean-Sebastien Parent, Tommaso Leonardi, Alan Hendrick, Tony Kouzarides & Robert A. Martienssen | Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA | 30 SPD | Thermo Orbitrap Exploris 480, Thermo Q Exactive HF | 30-spd | thermo-orbitrap-exploris-480 thermo-q-exactive-hf | |
The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence | Publication | 2024 | Shir Mass, Hadar Cohen, Ram Podicheti, Douglas B. Rusch, Motti Gerlic, Blake Ushijima, Julia C. van Kessel, Eran Bosis, Dor Salomon | Department of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel | Extended method | Thermo Q Exactive HF-X | extended-method | thermo-q-exactive-hf-x | |
Tea Polyphenols Inhibit Methanogenesis and Improve Rumen Epithelial Transport in Dairy Cows | Publication | 2024 | Zhanwei Teng, Shuai Liu, Lijie Zhang, Liyang Zhang, Shenhe Liu, Tong Fu, Ningning Zhang, and Tengyun Gao | College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China | 30 SPD | Thermo Orbitrap Exploris 480, Thermo Q Exactive HF-X | 30-spd | thermo-orbitrap-exploris-480 thermo-q-exactive-hf-x | |
Targeting Specific Kinase Substrates Rescues Increased Colitis Severity Induced by the Crohn’s Disease-Linked LRRK2-N2081D Variant | Publication | 2024 | George R. Heaton, Xianting Li, Xiaoting Zhou, Yuanxi Zhang, Duc Tung Vu, Marc Oeller, Ozge Karayel, Quyen Q. Hoang, Meltem Ece Kars, Minghui Wang, Leonid Tarassishin, Matthias Mann, Inga Peter, Zhenyu Yue | Department of Neurology, The Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, USA | 60 SPD | Thermo Orbitrap Astral | 60-spd | thermo-orbitrap-astral | |
Glutathione peroxidase 3 is a potential biomarker for konzo | Publication | 2024 | Vincent Kambale-Mastaki, Rafael Vincent M. Manalo, Aliyah Mohammed, David R. McIlwain, Gary Cunningham, Marshall Summar, Michael J. Boivin, Ljubica Caldovic, Eric Vilain, Dieudonne Mumba-Ngoyi, Desire Tshala-Katumbay & Arnaud Droit | Computational Biology Laboratory and The Proteomics Platform, CHU de Québec - Université Laval Research Center, Québec City, QC, Canada | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties | Publication | 2024 | Unai Mendibil, Yaiza Lópiz-Morales, Blanca Arnaiz, Raquel Ruiz-Hernández, Pablo Martín, Desiré Di-Silvio, Nerea Garcia-Urquia, Felix Elortza, Mikel Azkargorta, Beatriz Olalde, Ander Abarrategi | Center for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), Donostia-San Sebastian, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth | Publication | 2024 | Yuliya Kurlishchuk, Anita Cindric Vranesic, Marco Jessen, Alexandra Kipping, Christin Ritter, KyungMok Kim, Paul Cramer & Björn von Eyss | Leibniz-Institut für Altersforschung Fritz-Lipmann-Institut eV: Jena, Thüringen, Germany | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis | Publication | 2024 | Abdolhossein Zare, Saeede Salehi, Jakob Bader, Cornelius Schneider, Utz Fischer, Alexander Veh, Panagiota Arampatzi, Matthias Mann, Michael Briese & Michael Sendtner | Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg, Germany | Whisper 40 SPD | Bruker timsTOF Pro, Bruker timsTOF SCP | whisper-40spd | bruker-timstof-pro bruker-timstof-scp | |
Automated multiplexed affinity-based enrichment of peptides for LC-MS/MS plasma proteomics | Publication | 2024 | Sergio Mosquim Junior, Fredrik Levander | Department of Immunotechnology, Lund University, Lund, Sweden | 30 SPD | Thermo Q Exactive HF-X | 30-spd | thermo-q-exactive-hf-x | |
Loss of Lipooligosaccharide Synthesis in Acinetobacter baumannii Produces Changes in Outer Membrane Vesicle Protein Content | Publication | 2024 | Beatriz Cano-Castaño, Andrés Corral-Lugo, Eva Gato, María C. Terrón, Antonio J. Martín-Galiano, Javier Sotillo, Astrid Pérez, and Michael J. McConnell | Intrahospital Infections Laboratory, Instituto de Salud Carlos III (ISCIII), National Centre for Microbiology, Madrid, Spain | 100 SPD | Bruker timsTOF fleX | 100-spd | bruker-timstof-flex | |
Pollen-Food Allergy Syndrome: From Food Avoidance to Deciphering the Potential Cross-Reactivity between Pru p 3 and Ole e 7 | Publication | 2024 | Paula Álvarez, Rocío Aguado, Juan Molina, Antonio Trujillo-Aguilera, Mayte Villalba, Araceli Díaz-Perales, Carmen Oeo-Santos, Eduardo Chicano, Nadine Blanco, Ana Navas, Berta Ruiz-León, and Aurora Jurado | Department of Immunology and Allergy, Reina Sofía University Hospital, Córdoba, Spain | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Plasma proteomics and lipidomics facilitate elucidation of the link between Alzheimer’s disease development and vessel wall fragility | Publication | 2024 | Suzumi M. Tokuoka, Fumie Hamano, Ayako Kobayashi, Shungo Adachi, Tomohiro Andou, Tohru Natsume & Yoshiya Oda | Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan | Thermo Q Exactive HF | thermo-q-exactive-hf | |||
An NADH-controlled gatekeeper of ATP synthase | Publication | 2024 | Vasileios R Ouzounidis, Kate Jeffrey, Daniel-Cosmin Marcu, Francis J O’Reilly, Andrea Graziadei, Marchel Stuiver, Kita Schmidt, Helge Ewers, Christian MT Spahn, Ezgi Karaca, Karl Emanuel Busch, Dhanya Cheerambathur, David Schwefel, Juri Rappsilber | Technische Universität Berlin, Chair of Bioanalytics, Berlin, Germany | 60 SPD | Bruker timsTOF Ultra, Thermo Orbitrap Fusion Lumos | 60-spd | bruker-timstof-ultra thermo-orbitrap-fusion-lumos | |
An unconventional TOG domain is required for CLASP localization | Publication | 2024 | Nelly Gareil, Alison Gervais, Nicolas Macaisne, Guillaume Chevreux, Julie C. Canman, Jessica Andreani, Julien Dumont | Université Paris Cité, CNRS, Institut Jacques Monod, Paris, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
WHIX is a T6SS secretion domain found in polymorphic double-edged sword effectors | Publication | 2024 | Chaya Mushka Fridman, Kinga Keppel, Vladislav Rudenko, Jon Altuna-Alvarez, David Albesa-Jové, Eran Bosis, & Dor Salomon | Department of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical 8 and Health Sciences, Tel Aviv University, Tel Aviv, Israel | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
HSP110 is a modulator of amyloid beta (Aβ) aggregation and proteotoxicity | Publication | 2024 | Sabrina Montresor, Maria Lucia Pigazzini, Sudarson Baskaran, Mira Sleiman, Govinda Adhikari, Lukas Basilicata, Luca Secker, Natascha Jacob, Yara Ehlert, Anushree Kelkar, Gurleen Kaur Kalsi, Niraj Kulkarni, Paul Spellerberg, Janine Kirstein | Leibniz Institute on Aging—Fritz-Lipmann-Institute, Jena, Germany | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster | Publication | 2024 | Amrit S. Boese, Bryce M. Warner, Peter McQueen, Robert Vendramelli, Nikesh Tailor, Bryan D. Griffin, Mable Chan, Jonathan Audet, Anders Leung, Stuart McCorrister, Chris Grant, Garrett Westmacott & Darwyn Kobasa | Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada | Whisper 20 SPD | Thermo Orbitrap Exploris 480 | whisper-20spd | thermo-orbitrap-exploris-480 | |
vPro-MS enables identification of human-pathogenic viruses from patient samples by untargeted proteomics | Publication | 2024 | Marica Grossegesse, Fabian Horn, Andreas Kurth, Peter Lasch, Andreas Nitsche, Joerg Doellinger | Robert Koch Institute, Centre for Biological Threats and Special Pathogens: Highly Pathogenic Viruses (ZBS 1), WHO Collaboration Center for Emerging Treats and Special Pathogens | 60 SPD | Bruker timsTOF HT, Thermo Orbitrap Astral | 60-spd | bruker-timstof-ht thermo-orbitrap-astral | |
Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer | Publication | 2024 | Haleema Azam, Colin Veale, Kim Zitzmann, Simone Marcone, William M. Gallagher, Maria Prencipe | Cancer Biology and Therapeutics Laboratory, Conway Institute of Biomolecular and Biomedical Research, University College Dublin | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy | Publication | 2024 | Fiona Dick, Gard Aasmund Skulstad Johanson, Ole-Bjørn Tysnes, Guido Alves, Christian Dölle & Charalampos Tzoulis | Neuro-SysMed Center of Excellence for Clinical Research in Neurological Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway | 30 SPD | Thermo Orbitrap Eclipse Tribid | 30-spd | thermo-orbitrap-eclipse-tribid | |
An Inflection Point in High-Throughput Proteomics with Orbitrap Astral: Analysis of Biofluids, Cells, and Tissues | Publication | 2024 | Nathan G. Hendricks, Santosh D. Bhosale, Angel J. Keoseyan, Josselin Ortiz, Aleksandr Stotland, Saeed Seyedmohammad, Chi D. L. Nguyen, Jonathan T. Bui, Annie Morandian, Susan M. Mockus, Jennifer E. van Eyk | Precision Biomarker Laboratories, Cedars-Sinai Medical Center, Beverly Hills, California, United States | Thermo Orbitrap Astral | thermo-orbitrap-astral | |||
Peptide clustering enhances large-scale analyses and reveals proteolytic signatures in mass spectrometry data | Publication | 2024 | Erik Hartman, Fredrik Forsberg, Sven Kjellström, Jitka Petrlova, Congyu Luo, Aaron Scott, Manoj Puthia, Johan Malmström & Artur Schmidtchen | Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden | 30 SPD | Bruker timsTOF HT, Bruker timsTOF Pro | 30-spd | bruker-timstof-ht timstof-pro | |
Machine learning-based analysis identifies and validates serum exosomal proteomic signatures for the diagnosis of colorectal cancer Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue | Publication | 2024 | Haofan Yin, Jinye Xie, Shan Xing, Xiaofang Lu, Yu Yu, Yong Ren, Jian Tao, Guirong He, Lijun Zhang, Xiaopeng Yuan, Zheng Yang, Zhijian Huang | Department of Pathology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Distinct protein patterns related to postnatal development in small for gestational age preterm infants | Publication | 2024 | Eva R. Smit, Michelle Romijn, Pieter Langerhorst, Carmen van der Zwaan, Hilde van der Staaij, Joost Rotteveel, Anton H. van Kaam, Suzanne F. Fustolo-Gunnink, Arie J. Hoogendijk, Wes Onland, Martijn J. J. Finken & Maartje van den Biggelaar | Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Synaptic synergy of T cell receptor and interleukin 2 receptor in 2 CD8+ T cells | Publication | 2024 | Jesusa Capera, Ashwin K Jainarayanan, Salvatore Valvo, Lina Chen, Steven N Quayle, Raymond J Moniz , Anish Suri, Michael L Dustin | The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom | Bruker timsTOF Pro | timstof-pro | |||
The Comparative Analysis of Peptides in Enteral Nutrition Products and Foods for Special Medical Purposes | Publication | 2024 | Hao Li, Chenlu Fang, Yushan Hu, Jing Xu, Wei Zhao and Li Li | State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China | Thermo Orbitrap Exploris 120 | thermo-orbitrap-exploris-120 | |||
Multi-omics analysis reveals the impact of influenza a virus host adaptation on immune signatures in pig tracheal tissue | Publication | 2024 | Chrysillis Hellemann Polhaus, Charlotte Kristensen, Betina Lyngfeldt Henriksen, Yaolei Zhang, Louise Brogaard, Cathrine Agnete Larsen, Ramona Trebbien, Lars Erik Larsen, Kalogeropoulos Kalogeropoulos, Ulrich auf dem Keller, Kerstin Skovgaard | Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration | Publication | 2024 | Hyunggu Hahn, Carole Daly, John Little IV, Nicole A Perry-Hauser, Emmanuel Flores-Espinoza, Asuka Inoue, Bianca Plouffe, Alex Rojas Bie Thomsen | Department of Molecular Pathobiology, New York University College of Dentistry, New York, United States | Extended method | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | extended-method | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
Identification of a biomarker to predict doxorubicin/cisplatin chemotherapy efficacy in osteosarcoma patients using primary, recurrent and metastatic specimens | Publication | 2024 | Qiong Ma, Jin Sun, Qiao Liu, Jin Fu, Yanhua Wen, Fuqin Zhang, Yonghong Wu, Xiaoyu Zhang, Li Gong, Wei Zhang | Department of Pathology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome | Publication | 2024 | Alžběta Roeselová, Sarah L. Maslen, Jessica Zhiyun He, Gabija Jurkeviciute, J. Mark Skehel, Radoslav Enchev, David Balchin | Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Distinct protein patterns related to postnatal development in small for gestational age preterm infants | Publication | 2024 | Eva R. Smit, Michelle Romijn, Pieter Langerhorst, Carmen van der Zwaan, Hilde van der Staaij, Joost Rotteveel, Anton H. van Kaam, Suzanne F. Fustolo-Gunnink, Arie J. Hoogendijk, Wes Onland, Martijn J. J. Finken & Maartje van den Biggelaar | Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
The proteomic landscape of in vitro cultured endothelial cells across vascular beds | Publication | 2024 | Stijn A. Groten, Eva R. Smit, Maartje van den Biggelaar & Arie J. Hoogendijk | Department of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands | Extended method | Thermo Orbitrap Fusion Lumos | extended-method | thermo-orbitrap-fusion-lumos | |
The nonphototrophic hypocotyl 3 (NPH3) domain protein NRL5 is a trafficking-associated GTPase essential for drought resistance | Publication | 2024 | Neha Upadhyay-Tiwari, Xin-Jie Huang, Yi-Chen Lee, Shashi Kant Singh, Chuan-Chi Hsu, Shih-Shan Huang, and Paul E. Verslues | Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan | Extended method | Bruker timsTOF HT | extended-method | bruker-timstof-ht | |
An Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition | Publication | 2024 | Hui Jing, Paul L. Richardson, Gregory K. Potts, Sameera Senaweera, Violeta L Marin, Ryan McClure, Adam Banlasan, Hua Tang, James E. Kath, Renze Ma, Jon D. Williams | Discovery Research, AbbVie, Inc., 1 North Waukegan Rd., North Chicago, Illinois, United States | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Deep Visual Proteomics reveals DNA replication stress as a hallmark of Signet Ring Cell Carcinoma | Publication | 2024 | Sonja Kabatnik, Xiang Zheng, Georgios Pappas, Sophia Steigerwald, Matthew P Padula, Matthias Mann | NNF Center for Protein Research, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark | Whisper 40 SPD | Thermo Orbitrap Astral | whisper-40spd | thermo-orbitrap-astral | |
Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells | Publication | 2024 | Kaisa-Mari Launonen, Vera Varis, Niina Aaltonen, Einari A Niskanen, Markku Varjosalo, Ville Paakinaho, Jorma J Palvimo | Institute of Biomedicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer | Publication | 2024 | Yuqiu Shen, Oleta T. Johnson, Gabriela Grigorean, Brett Phinney, Liangren Liu, Qiang Wei, Eva Corey, Clifford G. Tepper, Hong-Wu Chen, Christopher P. Evans, Marc A. Dall’Era, Allen C. Gao, Jason E. Gestwicki & Chengfei Liu | Department of Urologic Surgery, University of California, Davis, CA, USA | Bruker timsTOF HT | bruker-timstof-ht | |||
Stage-dependent phosphoproteome remodeling of Parkinson’s disease blood cells | Publication | 2024 | Giorgia Massacci, Veronica Venafra, Maximilian Zwiebel, Maria Wahle, Rocco Cerroni, Jacopo Bissacco, Livia Perfetto, Vito Michienzi, Alessandro Stefani, Nicola Biagio Mercuri, Tommaso Schirinzi, Francesca Sacco | Department of Biology, University of Rome Tor Vergata, Rome, Italy | Bruker timsTOF Ultra | bruker-timstof-ultra | |||
Whole genome sequencing, proteomics, and function characterization of the Sinclair Nanopig™ for (bio) pharmaceuticals safety assessment | Publication | 2024 | Yafei Chen, Wendell P. Davis | Altasciences | Bruker timsTOF Pro 2 | timstof-pro-2 | |||
A non-autonomous protein quality control mechanism targeting tau aggregate propagation | Publication | 2024 | Nina Schulzea, Michal Strzalaa, Michelle Kocia, Farnusch Kaschania, Markus Kaisera, Michael Erkelenzc, Sebastian Schlueckerc, Melisa Merdanovica, Simon Poepseld, Doris Hellerschmieda, Steve Burstonf and Michael Ehrmann | Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Germany | 60 SPD | Thermo Orbitrap Fusion Lumos | 60-spd | thermo-orbitrap-fusion-lumos | |
Cryoprotectant-specific alterations in the proteome of Siberian sturgeon spermatozoa induced by cryopreservation | Publication | 2024 | Natalia Kodzik, Andrzej Ciereszko, Sylwia Judycka, Mariola Słowińska, Bożena Szczepkowska, Bianka Świderska & Mariola A. Dietrich | Department of Gamete and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
Comparison of the Proteome of Huh7 Cells Transfected with Hepatitis B Virus Subgenotype A1, with or without G1862T | Publication | 2024 | Kiyasha Padarath, Aurélie Deroubaix, Previn Naicker, Stoyan Stoychev and Anna Kramvis | Hepatitis Virus Diversity Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Science, University of Witwatersrand, Johannesburg, South Africa | |||||
De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments | Publication | 2024 | Sam P. B. van Beljouw, Marcin Skwark, Andreas Hougaard Laustsen, Stan J. J. Brouns, Anne Ljungers, Erwin M. Schoof, Jeroen Van Goey, Ulrich auf dem Keller, Karim Beguir, Nicolas Lopez Carranza and Timothy P. Jenkins | InstaDeep Ltd, 5 Merchant Square, London, UK | Whisper 40 SPD | Thermo Orbitrap Exploris 480 | whisper-40spd | thermo-orbitrap-exploris-480 | |
Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers | Publication | 2024 | Yaohui Sun, Zhiming Gan, Xiaojin Wang, Jian Liu, Wei Zhong, Zhiyan Zhang, Jiebin Zuo, Hang Zhong, Xiuting Huang, Zhixiang Yan & Qingdong Cao | Department of Thoracic Surgery and Lung Transplantation, The Fifth Affiliated Hospital of Sun Yat-Sen University, Guangdong, China | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments | Publication | 2024 | Francisco Romero-Gavilán, Carlos Arias-Mainer, Andreia Cerqueira, David Peñarrocha-Oltra, Juan Carlos Bernabeu-Mira, Iñaki García-Arnáez, Félix Elortza, María Muriach, Mariló Gurruchaga, Isabel Goñi & Julio Suay | Department of Industrial Systems Engineering and Design, Universitat Jaume I, Castellón de la Plana, Spain | Bruker timsTOF Pro | timstof-pro | |||
Comparison of the Amyloid Plaque Proteome in Down Syndrome, Early-Onset Alzheimer’s Disease and Late-Onset Alzheimer’s Disease | Publication | 2024 | Mitchell Martá-Ariza, Dominique F Leitner, Evgeny Kanshin, Jianina Suazo, Ana Giusti Pedrosa, Manon Thierry, Edward B. Lee, Orrin Devinsky, Eleanor Drummond, Juan Fortea, Alberto Lleó, Beatrix Ueberheide, Thomas Wisniewski | New York University Grossman School of Medicine | 15 SPD | Thermo Q Exactive HF-X | 15-spd | thermo-q-exactive-hf-x | |
Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice | Publication | 2024 | Jason R. Pitarresi, Dikla Atias, Eliana Steinberg, Tirza Bidany-Mizrahi, Esther Forkosh, Lior H. Katz, Ofra Benny, Talia Golan, Matan Hofree, Sheila A. Stewart, Karine A. Atlan, Gideon Zamir, Ben Z. Stanger, Michael Berger & Ittai Ben-Porath | Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Privacy-Preserving Multi-center Differential Protein Abundance Analysis with FedProt | Publication | 2024 | Julian Späth, Richard Röttger, Veit Schwämmle, Stefanie M. Hauck, Stefan Lichtenthaler, Axel Imhof, Matthias Mann, Christina Ludwig, Bernhard Kuster, Jan Baumbach, Olga Zolotareva | Chair of Proteomics and Bioanalytics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany | 30 SPD | Bruker timsTOF Pro, Thermo Orbitrap Exploris 480, Thermo Orbitrap Fusion Lumos, Thermo Q Exactive HF | 30-spd | timstof-pro thermo-orbitrap-exploris-480 thermo-orbitrap-fusion-lumos thermo-q-exactive-hf | |
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage | Publication | 2024 | Sara Diana Lolansen, Nina Rostgaard, Markus Harboe Olsen, Maud Eline Ottenheijm, Lylia Drici, Tenna Capion, Nicolas Hernandez Nørager, Nanna MacAulay & Marianne Juhler | Department of Neurosurgery, the Neuroscience Centre, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Substrate O-glycosylation actively regulates extracellular proteolysis | Publication | 2024 | Elizabeta Madzharova, Fabio Sabino, Konstantinos Kalogeropoulos, Chiara Francavilla, Ulrich auf dem Keller | Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark | Whisper 80 SPD | Thermo Orbitrap Exploris 480 | whisper-80-spd | thermo-orbitrap-exploris-480 | |
Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes | Publication | 2024 | Lisa M. Sevilla, Omar Pons-Alonso, Andrea Gallego, Mikel Azkargorta, Félix Elortza & Paloma Pérez | Instituto de Biomedicina de Valencia (IBV-CSIC), Department of Pathology and Molecular and Cell Therapy, Valencia, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway | Publication | 2024 | J. Huang, A. Jaekel, J. van den Boom, D. Podlesainski, M. Elnaggar, A. Heuer-Jungemann, M. Kaiser, H. Meyer & B. Saccà | Bionanotechnology, CENIDE and ZMB, University of Duisburg-Essen, Essen, Germany | 100 SPD, 60 SPD | 100-spd 60-spd | |||
Plasma proteome profiling for AKI biomarker candidates associated with first-line ART in people living with HIV in South Africa | Publication | 2024 | Rethabile J. Mokoenaa, Sylvia Fanucchib, Firdaus Nabeemeeahd, Ebrahim Variavad, Neil Martinsond, Ireshyn S. Govendera and Previn Naickera | NextGen Health, Council of Scientific and Industrial Research, Pretoria, Gauteng, South Africa | 60 SPD | 60-spd | |||
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics | Publication | 2024 | Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. Bush | Crick-GSK Biomedical LinkLabs, GSK, Gunnels Wood Road, Stevenage, Hertfordshire, UK | 30 SPD, 60 SPD | Bruker timsTOF Pro 2 | 30-spd 60-spd | timstof-pro-2 | |
Unraveling the differential mechanisms of revascularization promoted by MSCs & ECFCs from adipose tissue or umbilical cord in a murine model of critical limb-threatening ischemia | Publication | 2024 | Marta Rojas-Torres, Lucía Beltrán-Camacho, Ana Martínez-Val, Ismael Sánchez-Gomar, Sara Eslava-Alcón, Antonio Rosal-Vela, Margarita Jiménez-Palomares, Esther Doiz-Artázcoz, Mario Martínez-Torija, Rafael Moreno-Luna, Jesper V. Olsen & Ma. Carmen Duran-Ruiz | Biomedicine, Biotechnology and Public Health Department, University of Cadiz, Cadiz, Spain | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
The PP2A regulator IER5L supports prostate cancer progression | Publication | 2024 | Ianire Astobiza, Amaia Zabala-Letona, Marc Guiu, Mikel Azkargorta, Monika Gonzalez-Lopez, Nuria Macías-Cámara, Phuong Doan, Félix Elortza, Isabel Mendizabal, Jukka Westermack, Roger R. Gomis, Amaia Ercilla & Arkaitz Carracedo | Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Comparative Proteomics and Metabonomics Analysis of Different Diapause Stages Revealed a New Regulation Mechanism of Diapause in Loxostege sticticalis (Lepidoptera: Pyralidae) | Publication | 2024 | Lijun Shao, Fangzheng Yue, Jinfu Fan, Qin Su, Hairui Liu, Quanyi Zhang and Linbo Xu | Institute of Grassland Research, Chinese Academy of Agricultural Sciences, Hohhot, China | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Differences in the cerebral amyloid angiopathy proteome in Alzheimer’s disease and mild cognitive impairment | Publication | 2024 | Dominique Leitner, Tomas Kavanagh, Evgeny Kanshin, Kaleah Balcomb, Geoffrey Pires, Manon Thierry, Jianina I. Suazo, Julie Schneider, Beatrix Ueberheide, Eleanor Drummond & Thomas Wisniewski | Center for Cognitive Neurology, New York University Grossman School of Medicine, New York, NY, USA | 15 SPD | Thermo Q Exactive HF | 15-spd | thermo-q-exactive-hf | |
Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway | Publication | 2024 | Rubén Rodríguez-Agudo, Sofía Lachiondo-Ortega, Maria Mercado-Gómez, Teresa C. Delgado, Marina Porcelli, Igor Aurrekoetxea, James D. Sutherland, Rosa Barrio, Dimitris Xirodimas, Patricia Aspichueta, Felix Elortza, María L. Martínez-Chantar | Liver Disease Lab, CIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia, Spain | Bruker timsTOF Pro | timstof-pro | |||
Facing death: a multidisciplinary analysis of a Romano-Egyptian mummy mask at the Ny Carlsberg Glyptotek, Copenhagen | Publication | 2024 | Tuuli Kasso, Jens Stenger, Caterina Zaggia, Gianluca Pastorelli, Max Ramsøe, Tina Ravnsborg, Ole N. Jensen, Elsa Yvanez, Chiara Spinazzi-Lucchesi, Matthew J. Collins & Cecilie Brøns | Ny Carlsberg Glyptotek, Copenhagen, Denmark | 60 SPD | Thermo Q Exactive HF | 60-spd | thermo-q-exactive-hf | |
Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study | Publication | 2024 | Siyabonga Khoza, Jaya A. George, Previn Naicker, Stoyan H. Stoychev, June Fabian, Ireshyn S. Govender | Department of Chemical Pathology, National Health Laboratory Service and School of Pathology, University of the Witwatersrand, Faculty of Health Sciences, Johannesburg, South Africa | 60 SPD | 60-spd | |||
Repurposed 3D Printer Allows Economical and Programmable Fraction Collection for Proteomics of Nanogram Scale Samples | Publication | 2024 | Eduardo S. Kitano, Gareth NisbetYana Demyanenko, Katarzyna M Kowalczyk, Louisa Iselin, Stephen Cross, Alfredo Castello, Shabaz Mohammed | Rosalind Franklin Institute, Harwell Campus, Didcot, United Kingdom | 30 SPD | Thermo Orbitrap Ascend Tribid | 30-spd | thermo-orbitrap-ascend-tribid | |
Population scale proteomics enables adaptive digital twin modelling in sepsis | Publication | 2024 | Aaron M. Scott, Lisa Mellhammar, Erik Malmström, Axel Goch Gustafsson, Anahita Bakochi, Marc Isaksson, Tirthankar Mohanty, Louise Thelaus, Fredrik Kahn, Lars Malmström, Johan Malmström, Adam Linder | Division of Infection Medicine, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
VfENko-Kae01 is a flagellum-specific jumbo phage infecting Klebsiella aerogenes | Publication | 2024 | Kira Ranta, Mikael Skurnik & Saija Kiljunen | Human Microbiome Research Program, Research Program Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Towards routine proteome profiling of FFPE tissue: Insights from a 1,200 case pan-cancer study | Publication | 2024 | Lisa Hönikl, Vicki Butenschön, Rumyana Todorova, Hilka Rauert-Wunderlich, Matthew The, Andreas Rosenwald, Volker Heinemann, Julian Holch, Bernhard Meyer, Wilko Weichert, Carolin Mogler, Peer Hendrik-Kuhn, Bernhard Kuster | Proteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, Freising, Germany | 100 SPD, 15 SPD, 30 SPD | Thermo Orbitrap Exploris 480 | 100-spd 15-spd 30-spd | thermo-orbitrap-exploris-480 | |
Biophysical characteristics of NFkappaB-IkappaBalpha’s Intrinsically Disordered Regions | Publication | 2024 | Luis Oliva | University of California San Diego, CA, United States | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Early Holocene preservation differences between cortical and trabecular bone proteomes | Publication | 2024 | Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Maria Saña Seguí, Frido Welker | Globe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark | 60 SPD | Bruker timsTOF fleX, Thermo Orbitrap Exploris 480 | 60-spd | bruker-timstof-flex thermo-orbitrap-exploris-480 | |
Culturing Conditions Dictate the Composition and Pathways Enrichment of Human and Rat Perirenal Adipose-Derived Stromal Cells’ Secretomes | Publication | 2024 | Erika Pinheiro-Machado, Marijke M. Faas, Bart J. de Haan, Cyril Moers & Alexandra M. Smink | Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Quantitative measurement of lacritin in the tear fluid of patients with Dry Eye Disease | Publication | 2024 | Kyla Frenia, Ketan Dinghe, Yunxiang Fu, Jaclyn Sikora, Kathleen Garwood, Rick Mental, Dipanjan Pan, Kevin Xiao, Leanne Labriola | InnSight Technology Inc, Pittsburgh, Pennsylvania, United States | Bruker timsTOF Pro 2 | timstof-pro-2 | |||
Data for proteomic analysis of in situ digestion of alcohol-fixed cells for quantitative proteomics | Publication | 2024 | Atsushi Hatano, Masaki Matsumoto | Department of Omics and Systems Biology, Graduate School of Medical and Dental Sciences, Niigata University, Ichibancho, Asahimachi-dori, Chuo-ku, Niigata City, Niigata, Japan | Thermo Orbitrap Exploris 480, Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | thermo-orbitrap-exploris-480 thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |||
Rhythmic variation in proteomics: challenges and opportuninites for statistical power and biomarker identification | Publication | 2024 | Matt Spick, Cheryl M. Isherwood, Lee Gethings, Hana Hassanin, Daan R. van der Veen, Debra J. Skene, Jonathan D. Johnston | School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK | 60 SPD | 60-spd | |||
Dysregulation of Lipid Metabolism Serves as A Link Between Alzheimer’s and Cardiovascular Disease, As Witnessed in A Cross-Sectional Study | Publication | 2024 | Cristina Juarez-Alia1, Tamara Sastre-Oliva, Inés Perales-Sánchez, German Hernandez-Fernandez, Eduardo Chicano-Galvez, Ángela Peralbo-Molina, Felipe Madruga, Emilio Blanco-Lopez, Teresa Tejerina, María G. Barderas | Department of Vascular Physiopathology, Hospital Nacional de Paraplejicos, SESCAM, Toledo, Spain | Bruker timsTOF fleX | bruker-timstof-flex | |||
Localized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stress | Publication | 2024 | Austin O. Maduka, Sandhya Manohar, Matthew W. Foster, and Gustavo M. Silva | Department of Biology, Duke University, Durham, NC, USA | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |||
Visfatin impact on the proteome of porcine luteal cells during implantation | Publication | 2024 | Grzegorz Kopij, Marta Kiezun, Marlena Gudelska, Kamil Dobrzyn, Barbara Zarzecka, Edyta Rytelewska, Ewa Zaobidna, Bianka Swiderska, Agata Malinowska, Agnieszka Rak, Tadeusz Kaminski & Nina Smolinska | Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Spatial Proteomics of Single Hepatocytes with Multiplexed Data-Independent Acquisition (mDIA) | Publication | 2024 | Marvin Thielert, Caroline A. M. Weiss, Matthias Mann & Florian A. Rosenberger | Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
Nivolumab reaches brain lesions in patients with recurrent glioblastoma and induces T-cell activity and upregulation of checkpoint pathways | Publication | 2024 | Filip Mundt, Vilde Pedersen, Matthias Mann, Ib Jarle Christensen, Jane Skjøth-Ramussen, Christina Westmose Yde, Bjarne Winther Kristensen, Hans Skovgaard Poulsen, Benedikte Hasselbalch, Inge Marie Svane, Ulrik Lassen, Sine Reker Hadrup | Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Discovery of a novel antifungal compound, ilicicolin K, through genetic activation of the ilicicolin biosynthetic pathway in Trichoderma reesei | Publication | 2024 | Isabella Burger, Matthias Schmal, Kathrin Peikert, Lukas Fourtis, Christoph Suster, Christian Stanetty, Dominik Schnalzer, Ruth Birner-Gruenberger, Robert L Mach, Astrid R. Mach-Aigner, Matthias Schittmayer, Christian Zimmermann | Institute of Chemical Technologies and Analytics, TU Wien, Vienna, Austria | Whisper 40 SPD | Bruker timsTOF Pro | whisper-40spd | timstof-pro | |
Spatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaptation at the muscle-tendon transition zone | Publication | 2024 | Luisa Schmidt, Michael Saynisch, Christian Hoegsbjerg, Andreas Schmidt, Abigail Mackey, Jan-Wilm Lackmann, Stefan Müller, Manuel Koch, Bent Brachvogel, Michael Kjaer, Philipp Antczak, Marcus Krüger | Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany | Bruker timsTOF Pro 2, Thermo Orbitrap Eclipse Tribid | timstof-pro-2 thermo-orbitrap-eclipse-tribid | |||
Evolocumab as an immunomodulator in glioma: A window of opportunity trial evaluating PCSK9 inhibition to enhance surface MHC-I on tumor | Publication | 2024 | Allan Friedman, Stephen Keir, Evan D. Buckley, James E. Herndon, Roger E. McLendon, John H. Sampson, Evan Calabrese, Giselle Y. Lopez, Gerald A. Grant, Anoop P. Patel, Chuan-Yuan Li, Peter E. Fecci, Mustafa Khasraw | The Preston Robert Tisch Brain Tumor Center at Duke University, Durham, NC, US | 100 SPD, 60 SPD | Thermo Orbitrap Astral | 100-spd 60-spd | thermo-orbitrap-astral | |
Single cell proteomics by mass spectrometry reveals deep epigenetic insight into the actions of an orphan histone deacetylase inhibitor | Publication | 2024 | Benjamin C. Orsburn | The Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA, | 100 SPD, 200 SPD, 30 SPD, 500 SPD, 60 SPD | Bruker timsTOF SCP | 100-spd 200-spd 30-spd 500-spd 60-spd | bruker-timstof-scp | |
Highly Repeatable Tissue Proteomics for Kidney Transplant Pathology: Technical and Biological Validation of Protein Analysis using LC-MS/MS | Publication | 2024 | Rianne Hofstraat, Kristina Marx, Renata Blatnik, Nike Claessen, Aleksandra Chojnacka, Hessel PetersSengers, Sandrine Florquin, Jesper Kers, Garry Corthals | Department of Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Enabling scalable single-cell proteomics by utilizing the unique analytical properties of the Evotip Pure with new Whisper Zoom methods | Poster | 2024 | Frederik Haugaard Vrdlovec Holck, David Hartlmayr, Anjali Seth, Danté Johnson, Ole B. Hørning, Dorte B. Bekker-Jensen, Nicolai Bache | Evosep Biosystems | Whisper Zoom 120 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd whisper-zoom-40-spd whisper-zoom-80-spd | timstof-pro-2 | |
A complete and automated end-to-end sample preparation strategy for high-throughput and standardized proteomics with high sensitivity | Poster | 2024 | Magnus Huusfeldt, Hope Cabalo Zisco, Gabriel Bracamontes, Dorte B. Bekker-Jensen, Nicolai Bache | Evosep Biosystems | 100 SPD, 500 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF HT | 100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spd | bruker-timstof-ht | |
Standardized, fully automated neat plasma and Mag-Net enrichment workflows enabled by the Evotip Pure | Poster | 2024 | Joel Vej-Nielsen, Magnus Huusfeldt, Ian D. Shoemaker, Stoyan Stoychev, Laurent Rieux, Dorte B. Bekker-Jensen, Nicolai Bache | Evosep Biosystems | 200 SPD, 500 SPD | Bruker timsTOF HT | 200-spd 500-spd | bruker-timstof-ht | |
Scalability for high-throughput proteomics – Evotip Pure integration with the Biomek i5 liquid handler | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 200 SPD, 500 SPD | Bruker timsTOF HT | 200-spd 500-spd | bruker-timstof-ht | |
Cost-efficient and scalable end-to-end workflow on the Opentrons OT-2 for neat plasma utilizing Evotip Pure | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD, 200 SPD | Bruker timsTOF HT | 100-spd 200-spd | bruker-timstof-ht | |
Efficient proteomics with an automated sample preparation strategy leveraged by Evotip Pure and the AssayMAP Bravo | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD, 500 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF HT | 100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spd | bruker-timstof-ht | |
A specialized method for high sensitivity with the Whisper Zoom 20 samples per day method | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 20 SPD | Bruker timsTOF Pro 2 | whisper-zoom-20-spd | timstof-pro-2 | |
A specialized method for high sensitivity with the Whisper Zoom 40 samples per day method | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 40 SPD | Bruker timsTOF Pro 2 | whisper-zoom-40-spd | timstof-pro-2 | |
A specialized method for high sensitivity with the Whisper Zoom 80 samples per day method | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-80-spd | timstof-pro-2 | |
A specialized method for high sensitivity with the Whisper Zoom 120 samples per day method | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 120 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd | timstof-pro-2 | |
Whisper Zoom | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 120 SPD, Whisper Zoom 20 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd whisper-zoom-20-spd whisper-zoom-40-spd whisper-zoom-80-spd | timstof-pro-2 | |
Unlocking the plasma proteome | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD | Thermo Orbitrap Astral | 100-spd | thermo-orbitrap-astral | |
Whisper Zoom drives scalable workflows | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 120 SPD, Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd whisper-zoom-80-spd | timstof-pro-2 | |
Evotip Pure brings innovative sample storage | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 120 SPD, Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd whisper-zoom-80-spd | timstof-pro-2 | |
UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168 | Publication | 2024 | Daniel Salas-Lloret, Inge de Krijger, Nathalie Moatti, Ruben van der Lugt, Mattia Falcone, Aurora Cerutti, Onno B. Bleijerveld, Liesbeth Hoekman, Román González-Prieto & Jacqueline J. L. Jacobs | Division of Oncogenomics, The Netherlands Cancer Institute, Amsterdam, the Netherlands | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
An automated workflow based on data independent acquisition for practical and high-throughput personalized assay development and minimal residual disease monitoring in multiple myeloma patients | Publication | 2024 | Jolein Gloerich, Vincent Bonifay, Hélène Caillon, Theo M. Luider, Sven Brehmer, Lennard Pfennig, Tharan Srikumar, Dennis Trede, Gary Kruppa, Thomas Dejoie, Martijn M. van Duijn, Alain J. van Gool, Joannes F.M. Jacobs, Hans J.C.T. Wessels | Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Proteomic Characterisation of Placenta Tissue for Biomarker Discovery – Workflow Development and Application | Publication | 2024 | Tanja Peric, Selma Hevelius Bounja | Department of biomedical engineering, Lund university, Lund, Sweden | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
A co-culture system of macrophages with breast cancer tumoroids to study cell interactions and therapeutic responses | Publication | 2024 | Antonella Raffo-Romero, Lydia Ziane-Chaouche, Sophie Salomé-Desnoulez, Nawale Hajjaji, Isabelle Fournier, Michel Salzet, Marie Duhamel | Université Lille, Inserm, CHU Lille, Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), Equipe Labellisée Ligue Contre le Cancer, Lille, France | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Development of an efficient, effective, and economical technology for proteome analysis | Publication | 2024 | Katherine R. Martin, Ha T. Le, Ahmed Abdelgawad, Canyuan Yang, Guotao Lu, Jessica L. Keffer, Xiaohui Zhang, Zhihao Zhuang, Papa Nii Asare-Okai, Clara S. Chan, Mona Batish, Yanbao Yu | Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, USA | Thermo Orbitrap Eclipse Tribid | thermo-orbitrap-eclipse-tribid | |||
Multi Omics Applications in Biological Systems | Publication | 2024 | Cristian D. Gutierrez Reyes, Gerardo Alejo-Jacuinde, Benjamin Perez Sanchez, Jesus Chavez Reyes, Sherifdeen Onigbinde, Damir Mogut, Irma Hernández-Jasso, Denisse Calderón-Vallejo, J. Luis Quintanar, Yehia Mechref | Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA | Thermo Orbitrap Astral | thermo-orbitrap-astral | |||
Rapid Novor: Evosep One delivers high throughput and performance consistency in a clinical proteomics lab | Case study | 2024 | Evosep Biosystems | Evosep Biosystems | 60 SPD | 60-spd | |||
Engineering of TurboID-Wingless for the identification of Wingless interactors through in vivo proximity labelling | Publication | 2024 | Ana-Miruna Androniciuc, Edward W. Tate, Jean-Paul Vincent | The Francis Crick Institute, London, England, United Kingdom | 30 SPD | Bruker timsTOF Pro 2, Thermo Orbitrap Fusion Lumos | 30-spd | timstof-pro-2 thermo-orbitrap-fusion-lumos | |
Circulating pre- and postprandial extracellular vesicle proteomic profiles | Publication | 2024 | Alejandra P. Garza, Elisa Wider-Eberspächer, Lorena Morton, Marco van Ham, Éva Pállinger, Edit I. Buzás, Lothar Jänsch, Ildiko Rita Dunay | Otto-von-Guericke University Magdeburg, Magdeburg, Germany | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children | Publication | 2024 | Ulrikka Nygaard, Annelaura Bach Nielsen, Kia Hee Schultz Dungu, Lylia Drici, Mette Holm, Maud Eline Ottenheijm, Allan Bybeck Nielsen, Jonathan Peter Glenthøj, Lisbeth Samsø Schmidt, Dina Cortes, Inger Merete Jørgensen, Kjeld Schmiegelow, Matthias Mann | Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark | 300 SPD | Thermo Orbitrap Exploris 480 | 300-spd | thermo-orbitrap-exploris-480 | |
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response | Publication | 2024 | Yuxin Mi, Katie L. Burnham, Philip D. Charles, Raphael Heilig, Iolanda Vendrell, Justin Whalley, Hew D. Torrance, David B. Antcliffe, Shaun M. May, Matt J. Neville, Georgina Berridge, Paula Hutton, Cyndi G. Geoghegan, Jayachandran Radhakrishnan | Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK | 100 SPD | Bruker timsTOF Pro | 100-spd | timstof-pro | |
Global analysis of protein turnover dynamics in single cells | Publication | 2024 | Pierre Sabatier, Zilu Ye, Maico Lechner, Ulises H. Guzmán, Christian M. Beusch, Fabiana Izaguirre, Anjali Seth, Olga Gritsenko, Sergey Rodin, Karl-Henrik Grinnemo, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark | Whisper 40 SPD | Thermo Orbitrap Astral | whisper-40spd | thermo-orbitrap-astral | |
AlphaDIA enables End-to-End Transfer Learning for Feature-Free Proteomics | Publication | 2024 | Patricia Skowronek, Vincenth Brennsteiner, Mikhail Lebedev, Marvin Thielert, Sophia Steigerwald, Mohamed Kotb, Tim Heymann, Xie-Xuan Zhou, Magnus Schwoerer, Maximilian T. Strauss, Constantin Ammar, Sander Willems, Wen-Feng Zeng, Matthias Mann | Max-Planck Institute for Biochemistry; Novo Nordisk Foundation Center for Protein Research, Germany | 60 SPD, Whisper 40 SPD | Bruker timsTOF Pro 2 | 60-spd whisper-40spd | timstof-pro-2 | |
A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N labeled proteins | Publication | 2024 | Maria Wahle, Philip Remes, Vincent Albrecht, Johannes Bruno Mueller-Reif, Sophia Steigerwald, Lili Niu, Philip Loessl, Stevan Horning, Cristina Jacob, Matthias Mann | Max-Planck Institute for Biochemistry; Novo Nordisk Foundation Center for Protein Research, Germany | 30 SPD, 60 SPD | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
Elasticity Modification of Biomaterials Used in 3D Printing with an Elastin–Silk-like Recombinant Protein | Publication | 2024 | Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chru´scielewska, Katarzyna Kosowska, Iwona Sokołowska, Natalia Łukasiewicz, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła, Marta Klak | Foundation of Research and Science Development, Warsaw, Poland | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Hepatocellular RECK as a Critical Regulator of Metabolic Dysfunction-Associated Steatohepatitis Development | Publication | 2024 | Ryan J. Dashek, Rory P. Cunningham, Christopher L. Taylor, Isabella Alessi, Connor Diaz, Grace M. Meers, Andrew A. Wheeler, Jamal A. Ibdah, Elizabeth J. Parks, Tadashi Yoshida, Bysani Chandrasekar, R. Scott Rector | Research Service, Harry S Truman Memorial Veterans Medical Center, Columbia | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Deregulation of cellulose synthesis by site-directed mutagenesis of cellulose synthase leads to heightened bacterial cellulose production | Publication | 2024 | Daniel J. Upton, Heather Eastmond, Angharad Gatenby, Alexandra Lanot, Neil C. Bruce | CNAP, University of York, York, United Kingdom | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Dataset for evaluation of the lauryl maltose neopentyl glycol assisted sample preparation method | Publication | 2024 | Ryo Konno, Masaki Ishikawa, Daisuke Nakajima, Yusuke Endo, Osamu Ohara, Yusuke Kawashima | Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan | Whisper 80 SPD | Thermo Orbitrap Exploris 480 | whisper-80-spd | thermo-orbitrap-exploris-480 | |
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis | Publication | 2024 | Casey J. Lumpkin, Hiral Patel, Gregory K. Potts, Shilpi Chaurasia, Lauren Gibilisco, Gyan P. Srivastava, Janice Y. Lee, Nathan J. Brown, Patricia Amarante, Jon D. Williams, Eric Karran, Matthew Townsend, Dori Woods, Brinda Ravikumar | AbbVie, Cambridge Research Center, Cambridge, MA 02139, USA | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Beet supplementation mitigates post-exercise inflammation | Publication | 2024 | David C. Nieman, Camila A. Sakaguchi, James C. Williams, Fayaj A. Mulani, Patil Shivprasad Suresh, Ashraf M. Omar, Qibin Zhang | Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC, United States | Thermo Orbitrap Exploris 240 | thermo-orbitrap-exploris-240 | |||
Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats | Publication | 2024 | Peipei Dou, Xiaoyi Li, Xiaoxiao Zou, Kai Wang, Lei Yao, Zhuo Sun, Hui Hong, Yongkang Luo, Yuqing Tan | Key Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
A proteogenomic atlas of the human neural retina | Publication | 2024 | Michael Kwint, Jolein Gloerich, Hans J.C.T. Wessels, Elfride De Baere, Filip van Nieuwerburgh, Sarah De Keulenaer, Barbara Ferrari, Stefano Ferrari, Frauke Coppieters, Frans P.M. Cremers, Erwin van Wyk, Susanne Roosing, Erik de Vrieze, Peter A.C. ‘t Hoen | Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles | Publication | 2024 | Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy & Zoltán Giricz | Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary | 30 SPD | 30-spd | |||
Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes | Publication | 2024 | Arthur Viode, Kinga K. Smolen, Patrick van Zalm, David Stevenson, Meenakshi Jha, Kenneth Parker, Ofer Levy, Judith A. Steen, Hanno Steen | Department of Pathology, Boston Children’s Hospital, Boston, MA, USA | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
A Novel Approach to Orthotopic Hepatocyte Transplantation Engineered With Liver Hydrogel for Fibrotic Livers, Enhancing Cell–Cell Interaction and Angiogenesis | Publication | 2024 | Daisuke Udagawa, Shogo Nagata, Hiroshi Yagi, Kotaro Nishi, Toshinori Morisaku, Shungo Adachi, Yutaka Nakano, Masayuki Tanaka, Shutaro Hori, Yasushi Hasegawa, Yuta Abe, Minoru Kitago, Yuko Kitagawa | Department of Surgery, Keio University School of Medicine, Tokyo, Japan | Thermo Q Exactive HF-X | thermo-q-exactive-hf-x | |||
Fully automated workflow for integrated sample digestion and Evotip loading enabling high-throughput clinical proteomics | Publication | 2024 | Anders H. Kverneland, Florian Harking, Joel Mario Vej-Nielsen, Magnus Huusfeldt, Dorte B. Bekker-Jensen, Inge Marie Svane, Nicolai Bache, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark | 100 SPD, 60 SPD | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | 100-spd 60-spd | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
GLP-1-directed NMDA receptor antagonism for obesity treatment | Publication | 2024 | Luisa Sachs, Roger Moreno-Justicia, Rebecca Rohlfs, James C. Ford, Jonathan D. Douros, Brian Finan, Bryan Portillo, Kyle Grose, Jacob E. Petersen, Mette Trauelsen, Annette Feuchtinger, Richard D. DiMarchi, Thue W. Schwartz, Christoffer Clemmensen | Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
The balance between antiviral and antibacterial responses during M. Tuberculosis infection is regulated by the ubiquitin ligase CBL | Publication | 2024 | Tina Truong, Kelsey Martin, Michelle Salemi, Abigail Ray, Brett S. Phinney, Bennett H. Penn | Department of Internal Medicine, University of California, Davis, Davis, California, United States of America | 30 SPD, 60 SPD | Bruker timsTOF HT, Bruker timsTOF Pro 2 | 30-spd 60-spd | bruker-timstof-ht timstof-pro-2 | |
NPEPPS Is a Druggable Driver of Platinum Resistance | Publication | 2024 | Shahla Romal, Cailin Deiter, Tsung Wai Kan, Nathaniel Xander, Stephanie P. Araki, Molishree Joshi, Mahmood Javaid, Eric T. Clambey, Ryan Layer, Teemu D. Laajala, Sarah J. Parker, Tokameh Mahmoudi, Tahlita C.M. Zuiverloon, Dan Theodorescu, James C Costello | Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants | Publication | 2024 | Chao Yang, Abhijeet Pataskar, Xiaodong Feng, Celia R. Berkers, Onno B. Bleijerveld, Reuven Agami | Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
A multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities | Publication | 2024 | Christian Panse, Karel Stejskal, Thibaut Douché, Bérangère Lombard, Andrea Schuhmann, Damarys Loew, Karl Mechtler, Mariette Matondo, Mandy Rettel, Dominic Helm, Francis Impens, Simon Devos, Anna Shevchenko, Paolo Nanni, Eduard Sabidó | Centre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain | 15 SPD, Whisper 20 SPD | Thermo Q Exactive HF | 15-spd whisper-20spd | thermo-q-exactive-hf | |
Scalability for high-throughput proteomics – Evotip Pure integration with the Biomek i5 liquid handler | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 200 SPD, 500 SPD | Bruker timsTOF HT | 200-spd 500-spd | bruker-timstof-ht | |
Cost-efficient and scalable end-to-end workflow on the Opentrons OT-2 for neat plasma utilizing Evotip Pure | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD, 200 SPD | Bruker timsTOF HT, SCIEX ZenoTOF 7600 | 100-spd 200-spd | bruker-timstof-ht sciex-zenotof-7600 | |
Efficient proteomics with an automated sample preparation strategy leveraged by Evotip Pure and the AssayMAP Bravo | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD, 500 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF HT | 100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spd | bruker-timstof-ht | |
Unlocking the plasma proteome with Evotip Pure based, standardized and scalable workflows | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | 100 SPD | Thermo Orbitrap Astral | 100-spd | thermo-orbitrap-astral | |
Whisper Zoom drives scalable workflows for high-sensitivity applications through standardization and ease-of-use | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | Whisper Zoom 120 SPD, Whisper Zoom 20 SPD, Whisper Zoom 40 SPD, Whisper Zoom 80 SPD | Bruker timsTOF Pro 2 | whisper-zoom-120-spd whisper-zoom-20-spd whisper-zoom-40-spd whisper-zoom-80-spd | timstof-pro-2 | |
Evotip Pure brings innovative sample storage and introduction to high-sensitivity and scalable LC-MS workflows | Application note | 2024 | Evosep Biosystems | Evosep Biosystems | |||||
Integrated proteogenomic analysis for inherited bone marrow failure syndrome | Publication | 2024 | Manabu Wakamatsu, Hideki Muramatsu, Hironori Sato, Masaki Ishikawa, Ryo Konno, Daisuke Nakajima, Motoharu Hamada, Yusuke Okuno, Yusuke Kawashima, Asahito Hama, Masafumi Ito, Hideto Iwafuchi, Yoshiyuki Takahashi & Osamu Ohara | Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis | Publication | 2024 | Mengjie Yang, Hong Jiang, Xinyu Ding, Lu Zhang, Huaying Zhang, Jiahao Chen, Lijun Li, Xinqin He, Zhixiong Huang & Qionghua Chen | Clinical Medical Research Center for Gynecological Reproductive Health of Fujian Province, Laboratory of Research and Diagnosis of Gynecological Diseases of Xiamen City, China | 15 SPD | Bruker timsTOF Pro | 15-spd | timstof-pro | |
The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base— reveals signicant changes in host cell protein expression and activation by multiple SARS-CoV-2 variants | Publication | 2024 | Sini Huuskonen, Xiaonan Liu, Taras Redchuk, Kari Salokas, Rickard Lundberg, Sari Maljanen, Milja Belik, Arttu Reinholm, Pekka Kolehmainen, Garima Tripathi, Pia Laine, Sergei Belanov, Petri Auvinen, Maria Vartiainen, Larissa Laine | The university of Helsinki, Helsinki, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells | Publication | 2024 | Luisa Weisbrod, Luigi Capriotti, Marco Hofmann, Valerie Spieler, Herbert Dersch, Bernd Voedisch, Peter Schmidt, Susanne Knake | Recombinant Protein Discovery, CSL Innovation GmbH, Marburg, Germany | Extended method | Thermo Orbitrap Exploris 240 | extended-method | thermo-orbitrap-exploris-240 | |
Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation | Publication | 2024 | Frederik Post, Annika Hausmann, Sonja Kabatnik, Sophia Steigerwald, Alexandra Brand, Ditte Lange Clement, Jonathan Skov, Theresa Louise Boye, Toshiro Sato, Casper Steenholdt, Andreas Mund, Ole Haagen Nielsen, Kim Bak Jensen, Matthias Mann | Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark | Whisper 40 SPD | Thermo Orbitrap Astral | whisper-40spd | thermo-orbitrap-astral | |
Comparative proteomic analysis of the ovarian fluid and eggs of Siberian sturgeon | Publication | 2024 | Natalia Kodzik, Andrzej Ciereszko, Bożena Szczepkowska, Agata Malinowska & Mariola Aleksandra Dietrich | Department of Gamete and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Poland | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Unraveling the proteome landscape of mouse hematopoietic stem and progenitor compartment with high sensitivity low-input proteomics | Publication | 2024 | Nil Üresin, Valdemaras Petrosius, Pedro Aragon-Fernandez, Benjamin Furtwängler, Erwin M. Schoof, & Bo T. Porse | The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen,Copenhagen, Denmark. | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Machine learning strategies to tackle data challenges in mass spectrometry-based proteomics | Publication | 2024 | Ceder Dens, Charlotte Adams, Kris Laukens, Wout Bittremieux | Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerpen, Belgium | Bruker timsTOF Pro | timstof-pro | |||
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics | Publication | 2024 | Stephan Eckert, Nicola Berner, Karl Kramer, Annika Schneider, Julian Müller, Severin Lechner, Sarah Brajkovic, Amirhossein Sakhteman, Christian Graetz, Jonas Fackler, Michael Dudek, Michael W. Pfaffl, Percy Knolle, Stephanie Wilhelm & Bernhard Kuster | Proteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, Freising, Germany | Thermo Orbitrap Eclipse Tribid | thermo-orbitrap-eclipse-tribid | |||
Mass Spectrometry-Based Proteomics to Evaluate the Circulating Proteome in Idiopathic Pulmonary Fibrosis (IPF) | Publication | 2024 | A. A. Menon, H. Mulder, M. L. Neely, F. Meissner, B. Gansen, P. Papavasileiou, C. Hesslinger, M. L. Salisbury, B. D. Southern, T. B. Leonard, J. L. Todd | Medical University of South Carolina, Charleston, SC, United States | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant | Publication | 2024 | Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V. Lukassen, Henk van den Toorn, Maurits A. den Boer, Albert Bondt, Sjors P. A. van der Lans, Pieter-Jan Haas, Arjan D. van Zuilen, Suzan H. M. Rooijakkers, and Albert J. R. Heck | Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
The proteomic profile is altered but not repaired after bariatric surgery in type 2 diabetes pigs | Publication | 2024 | Karolina Ferenc, Michał Marcinkowski, Jarosław Olszewski, Paweł Kowalczyk, Tomaš Pilžys, Damian Garbicz, Naser Dib, Bianka Świderska, Piotr Matyba, Zdzisław Gajewski, Elżbieta Grzesiuk & Romuald Zabielski | Center for Translational Medicine, Warsaw University of Life Sciences, Warsaw, Poland | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Plasma/Serum Proteomics based on Mass Spectrometry | Publication | 2024 | Yiying Zhu | Department of Chemistry, Tsinghua University, Beijing, China | Thermo Orbitrap Astral | thermo-orbitrap-astral | |||
Reduced ATP turnover during hibernation in relaxed skeletal muscle | Publication | 2024 | Cosimo de Napoli, Luisa Schmidt, Mauro Montesel, Laura Cussonneau, Samuele Sanniti, Lorenzo Marcucci, Elena Germinario, Jonas Kindberg, Alina Evans, Guillemette Gauquelin-Koch, Fabrice Bertile, Etienne Lefai, Marcus krüger, Leonardo Nogara | Department of Biomedical Science University of Padova, Italy | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Optimization of protocols for blood-derived extracellular vesicles for studies in liver diseases | Publication | 2024 | Magnolia Martínez-Aguilar, María Camila Trillos-Almanza, Justina C. Wolters, Manon Buist-Homan, TransplantLines Investigators, Frederike van Vilsteren, Hans Blokzijl, Han Moshage | Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Ribosomal composition affects the noncanonical translation and toxicity of polyglycine-containing proteins in fragile X-associated conditions | Publication | 2024 | Katarzyna Tutak, Izabela Broniarek, Andrzej Zielezinski, Daria Niewiadomska, Anna Baud, Krzysztof Sobczak | Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Poznan, Poland | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Urinary Proteomics and Outcomes in Heart Failure With Preserved Ejection Fraction | Publication | 2024 | Yixin Wang, Peter H. Schafer, Sarah Hersey, Leonidas N. Carayannopoulos, Dietmar Seiffert, Ching‐Pin Chang, David A. Gordon, Francisco Ramirez‐Valle, Douglas L. Mann, Thomas P. Cappola and Julio A. Chirinos | University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Characterization of a Chimeric Resilin-Elastin Structural Protein Dedicated to 3D Bioprinting as a Bioink Component | Publication | 2024 | Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chruścielewska, Katarzyna Kosowska, Natalia Łukasiewicz, Iwona Sokołowska, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła and Marta Klak | Foundation of Research and Science Development, Warsaw, Poland | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Spatial Proteomics Reveals Alcohol-Induced Damages to the Crypts and Villi of the Mouse Small Intestine | Publication | 2024 | Patil Shivprasad Suresh, Xinguo Sun, Zhanxiang Zhou, and Qibin Zhang | Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States | 30 SPD | Thermo Orbitrap Exploris 240 | 30-spd | thermo-orbitrap-exploris-240 | |
O-linked glycosylations in human milk casein and major whey proteins during lactation | Publication | 2024 | Martin Nørmark Thesbjerg, Katrine Overgaard Poulsen, Julie Astono, Nina Aagaard Poulsen, Lotte Bach Larsen, Søren Drud-Heydary Nielsen, Allan Stensballe, Ulrik Kræmer Sundekilde | Department of Food Science, Aarhus University, Agro Food Park 48, Aarhus N, Denmark | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids | Publication | 2024 | Chaitanya Dingare, Dominica Cao, Jenny Jingni Yang, Berna Sozen, Benjamin Steventon | Deptartment of Genetics, University of Cambridge, Downing Site, Cambridge, UK | 500 SPD | Bruker timsTOF HT, Thermo Orbitrap Exploris 240 | 500-spd | bruker-timstof-ht thermo-orbitrap-exploris-240 | |
Theabrownin ameliorated lipid accumulation via modulating circadian rhythms in oleic acid-induced HepG2 cells | Publication | 2024 | Chunyan Zhao, Lei Zhao, Zelin Li, Yue Miao, Shuwen Lei, Bo Shan, Qiuping Wang, Chao Tan, Chunxiu Peng, Jiashun Gong | College of Food Science and Technology, Yunnan Agricultural University, Kunming, China | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Increasing sustainability in palaeoproteomics by optimizing digestion times for large-scale archaeological bone analyses | Publication | 2024 | Louise Le Meillour, Virginie Sinet-Mathiot, Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Dorothea Mylopotamitaki, Gaudry Troché, Huan Xia, Jorsua Herrera Bethencourt, Karen Ruebens, Geoff M. Smith, Zandra Fagernäs, Frido Welker | University of Copenhagen, Copenhagen, Denmark | 100 SPD | Thermo Orbitrap Exploris 480 | 100-spd | thermo-orbitrap-exploris-480 | |
The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing | Publication | 2024 | Matheus H Dias, Vladyslava Liudkovska, Jasmine Montenegro Navarro, Lisanne Giebel, Julien Champagne, Chrysa Papagianni, Onno B Bleijerveld, Arno Velds, Reuven Agami, René Bernards & Maciej Cieśla | Division of Molecular Carcinogenesis and Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage | Publication | 2024 | James Barrett, Mihris I.S. Naduthodi, Yuwei Mao, Clément Dégut, Sabina Musiał, Aidan Salter, Mark C. Leake, Michael J. Plevin, Alistair J. McCormick, James N. Blaza, Luke C.M. Mackinder | Department of Biology, University of York, York, UK | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Craspase Orthologs Cleave a Nonconserved Site in Target Protein Csx30 | Publication | 2024 | Sam P. B. van Beljouw, Anna C. Haagsma, Konstantinos Kalogeropoulos, Martin Pabst, Stan J. J. Brouns | Department of Bionanoscience, Delft University of Technology, Delft, Netherlands | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Relaxation of mucosal fibronectin fibers in late gut inflammation following neutrophil infiltration in mice | Publication | 2024 | Ronja Rappold, Konstantinos Kalogeropoulus, Ulrich auf dem Keller, Emma Slack, Viola Vogel | ETH Zürich, Switzerland | Whisper 20 SPD | Thermo Orbitrap Exploris 480 | whisper-20spd | thermo-orbitrap-exploris-480 | |
Craspase Orthologs Cleave a Nonconserved Site in Target Protein Csx30 | Publication | 2024 | Sam P. B. van Beljouw, Anna C. Haagsma, Konstantinos Kalogeropoulos, Martin Pabst, and Stan J. J. Brouns | Department of Bionanoscience, Delft University of Technology, Delft, Netherlands | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Global organization of phenylpropanoid and anthocyanin pathways revealed by proximity labeling of trans-cinnamic acid 4-hydroxylase (CYP73A412) in Petunia inflata petal protoplasts | Publication | 2024 | Javiera Aravena-Calvo, Silas Busck-Mellor, Tomas Laursen | Department of Plant and Environmental Sciences (PLEN), Section for Plant Biochemistry, University of Copenhagen, Denmark | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine Model | Publication | 2024 | Anna Faragó, Ágnes Zvara, László Tiszlavicz, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Zoltán Hegedűs, Enikő Szabó, Sára Eszter Surguta, József Tóvári, László G. Puskás, and Gábor J. Szebeni | Astridbio Technologies Ltd., Wimmer Fülöp utca 1, Hungary | 15 SPD | Thermo Orbitrap Fusion Lumos | 15-spd | thermo-orbitrap-fusion-lumos | |
Enrichment, Characterization, and Proteomic Profiling of Small Extracellular Vesicles Derived from Human Limbal Mesenchymal Stromal Cells and Melanocytes | Publication | 2024 | Sebastian Kistenmacher, Melanie Schwämmle, Gottfried Martin, Eva Ulrich, Stefan Tholen, Oliver Schilling, Andreas Gießl, Ursula Schlötzer-Schrehardt, Felicitas Bucher, Günther Schlunck, Irina Nazarenko, Thomas Reinhard and Naresh Polisetti | Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany | 30 SPD | Bruker timsTOF fleX | 30-spd | bruker-timstof-flex | |
Exploring the role of production and release of proteins for microbial interactions in kombucha | Publication | 2024 | Jacqueline Rodriguez Rey, Thierry Tran, Amaury Aumeunier, Aurélie Rieu, François Verdier, Antoine Martin, Hervé Alexandre, Raphaëlle Tourdot-Maréchal, Cosette Grandvalet | UMR PAM 1517, Université Bourgogne, Institut Agro, Dijon, France | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies | Publication | 2024 | Jonah F. Byrne, Colm Healy, Melanie Föcking, Meike Heurich, Subash Raj Susai, David Mongan, Kieran Wynne, Eleftheria Kodosaki, Scott W. Woods, Barbara A. Cornblatt, William S. Stone, Daniel H. Mathalon, Carrie E. Bearden, Kristin S. Cadenhead, Jean Adding | Department of Psychiatry, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin, Ireland | Bruker timsTOF Pro | timstof-pro | |||
Extracellular vesicles derived CXCL4 is a candidate serum tumor biomarker for colorectal cancer | Publication | 2024 | Jinye Xie, Shan Xing, Hongbo Jiang, Jiaju Zhang, Daxiao Li, Shiqiong Niu, Zhijian Huang, and Haofan Yin | Department of Laboratory Medicine, Zhongshan City People’s Hospital, Zhongshan, Guangdong, China | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication | Publication | 2024 | Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton | Organelle Dynamics Laboratory, The Francis Crick Institute, London, UK | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
Cheap, Robust and Versatile Two-Dimensional Chromatography system for Proteomics of Nanogram Scale Samples | Publication | 2024 | Eduardo S. Kitano, Gareth Nisbet, Yana Demyanenko, Katarzyna M Kowalczyk, Louisa Iselin, Stephen Cross, Alfredo Castello, Shabaz Mohammed | Rosalind Franklin Institute, Harwell Campus, United Kingdom | 30 SPD | Thermo Orbitrap Ascend Tribid | 30-spd | thermo-orbitrap-ascend-tribid | |
Matrimeres are systemic nanoscale mediators of tissue integrity and function | Publication | 2024 | Koushik Debnath, Irfan Qayoom, Steven O’Donnell, Julia Ekiert, Can Wang, Mark A. Sanborn, Chang Liu, Ambar Rivera, Ik Sung Cho, Saiumamaheswari Saichellappa, Peter T. Toth, Dolly Mehta, Jalees Rehman, Xiaoping Du, Yu Gao, and Jae-Won Shin | Department of Pharmacology and Regenerative Medicine, College of Medicine, Chicargo, IL, USA | 60 SPD | Thermo Q Exactive HF | 60-spd | thermo-q-exactive-hf | |
Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies | Publication | 2024 | Dmytro Morderer, Melissa C. Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil, Nora Pobitzer, Michelle Salemi, Brett S. Phinney, Dennis W. Dickson, Melissa E. Murray and Wilfried Rossoll | Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA | 100 SPD | Bruker timsTOF Pro 2 | 100-spd | timstof-pro-2 | |
Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles | Publication | 2024 | George Haddad, Judith Blaine | Division of Renal Disease and Hypertension, Department of Medicine, School of Medicine, University of Colorado, Aurora, USA | Bruker timsTOF SCP | bruker-timstof-scp | |||
DIP-MS: ultra-deep interaction proteomics for the deconvolution of protein complexes | Publication | 2024 | Fabian Frommelt, Andrea Fossati, Federico Uliana, Fabian Wendt, Peng Xue, Moritz Heusel, Bernd Wollscheid, Ruedi Aebersold, Rodolfo Ciuffa & Matthias Gstaiger | Department of Biology, Institute of Molecular Systems Biology, Zurich, Switzerland | 60 SPD | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | 60-spd | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
RNA damage compartmentalization by DHX9 stress granules | Publication | 2024 | Yilong Zhou, Amol Panhale, Maria Shvedunova, Mirela Balan, Alejandro Gomez-Auli, Herbert Holz, Janine Seyfferth, Martin Helmstädter, Séverine Kayser, Yuling Zhao, Niyazi Umut Erdogdu, Iga Grzadzielewska, Gerhard Mittler, Thomas Manke, and Asifa Akhtar | Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
NFATC2IP is a mediator of SUMO- dependent genome integrity | Publication | 2024 | Tiffany Cho, Lisa Hoeg, Dheva Setiaputra, and Daniel Durocher | Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series | Publication | 2024 | Travis Nemkov, Francesca Cendali, Monika Dzieciatkowska, Daniel Stephenson, Kirk C. Hansen, Catherine M. Jankowski, Angelo D’Alessandro and Ryan J. Marker | Department of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, USA | Bruker timsTOF Pro | bruker-timstof-pro | |||
Integrating multiplex-staining and multiplex-DIA: Profiling the tumor microenvironment spatial proteome for precision cancer research | Publication | 2024 | Xiang Zheng, Andreas Mund, Matthias Mann | University of Copenhagen, Copenhagen, Denmark | Bruker timsTOF SCP | bruker-timstof-scp | |||
Molecular interactions of human receptor tyrosine kinase oncogenic fusions | Publication | 2024 | Giovanna Dashi, Markku Varjosalo | University of Helsinki, Helsinki, Finland | Bruker timsTOF Pro | bruker-timstof-pro | |||
A T6SS in the coral pathogen Vibrio coralliilyticus secretes an arsenal of anti-eukaryotic effectors and contributes to virulence | Publication | 2024 | Shir Mass, Hadar Cohen, Motti Gerlic, Blake Ushijima, Julia C. van Kessel, Eran Bosis, and Dor Salomon | Department of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Israel | 15 SPD | Thermo Q Exactive HF | 15-spd | thermo-q-exactive-hf | |
Proteomic study of left ventricle and cortex in rats after myocardial infarction | Publication | 2024 | Mengli Chang, Huanhuan Wang, Yuxin Lei, Hongjun Yang, Jing Xu & Shihuan Tang | Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China | Thermo Q Exactive HF-X | thermo-q-exactive-hf-x | |||
Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations | Publication | 2024 | Eirini Tsirvouli, Ana Martinez del Val, Liv Thommesen, Astrid Lægreid, Martin Kuiper, Jesper Olsen, Åsmund Flobak | Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Proteomic Analysis Reveals Trilaciclib-Induced Senescence | Publication | 2024 | Marina Hermosilla-Trespaderne, Mark Xinchen Hu-Yang, Abeer Dannoura, Andrew M. Frey, Amy L. George, Matthias Trost, José Luis Marín-Rubio | Biosciences Institute, Newcastle University, Newcastle-upon-Tyne, UK | 100 SPD | Bruker timsTOF HT | 100-spd | bruker-timstof-ht | |
Widespread S-persulfidation in activated macrophages as a protective mechanism against oxidative-inflammatory stress | Publication | 2024 | Talal Salti, Ilana Braunstein, Yael Haimovich, Tamar Ziv, Moran Benhar | Department of Biochemistry, Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel | 15 SPD | Thermo Q Exactive HF | 15-spd | thermo-q-exactive-hf | |
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy | Publication | 2024 | Aristeidis Panagiotou, Aurélie Richard, Angélique Amo, Yulianna Koziy, Souhila Medjkane, Sergio Valente, Rossella Fioravanti, Catherine Pioche-Durieu, Laurent Lignière, Guillaume Chevreux, Antonello Mai & Jonathan B. Weitzman | Université Paris Cité, CNRS, UMR7126 Epigenetics and Cell Fate, Paris, France | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Human Dermal Decellularized ECM Hydrogels as Scaffolds for 3D In Vitro Skin aging Models | Publication | 2024 | Estibaliz Fernandez‐Carro, Ana Rosa Remacha, Irene Orera, Giuseppe Lattanzio, Alberto Garcia‐Barrios, Jesús del Barrio, Clara Alcaine and Jesús Ciriza | Tissue Microenvironment (TME) Lab. Aragón Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production | Publication | 2024 | Moeka Nobe, Yuhei Maruzuru, Kosuke Takeshima, Fumio Maeda, Hideo Kusano, Raiki Yoshimura, Takara Nishiyama, Hyeongki Park, Yoshitaka Kozaki, Shingo Iwami, Naoto Koyanagi, Akihisa Kato1, Tohru Natsume, Shungo Adachi, and Yasushi Kawaguchi | Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Japan | 100 SPD | Thermo Q Exactive HF-X | 100-spd | thermo-q-exactive-hf-x | |
Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation | Publication | 2024 | Javier G. Casado, Eva Pericuesta, Alfonso Gutiérrez-Adán, Esperanza González, Mikel Azkargorta, Ricardo Conde, Maider Bizkarguenaga, Nieves Embade, Félix Elortza, Juan M. Falcón-Pérez, Óscar Millet, Lauro González-Fernández, Beatriz Macías-García | Departamento de Medicina Animal, Facultad de Veterinaria, Grupo de Investigación Medicina Interna Veterinaria (MINVET), Instituto de Investigación INBIO G+C, Universidad de Extremadura, Cáceres, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Personalized phosphoproteomics of skeletal muscle insulin resistance and exercise links MINDY1 to insulin action | Publication | 2024 | Johan D. Onslev, Alexis Diaz-Vegas, Magnus R. Leandersson, Jonas Møller Kristensen, Kohei Kido, Erik A. Richter, Kurt Højlund, Benjamin L. Parker, Kristen Cooke, Guang Yang, Christian Pehmøller, Sean J. Humphrey, David E. James, Jørgen F.P. Wojtaszewski | Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, New South Wales, Australia | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease | Publication | 2024 | Sephira Ryman, Maya Yutsis, Gayle K. Deutsch, Elizabeth Mormino, Alexandra Trelle, Anthony D. Wagner, Geoffrey A. Kerchner, Lu Tian, Carlos Cruchaga, Victor W. Henderson, Thomas J. Montine, Per Borghammer, Tony Wyss-Coray & Kathleen L. Poston | Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA, USA | Bruker timsTOF Pro | timstof-pro | |||
AlphaPept: a modern and open framework for MS-based proteomic | Publication | 2024 | Maximilian T. Strauss, Isabell Bludau, Wen-Feng Zeng, Eugenia Voytik, Constantin Ammar, Julia P. Schessner, Rajesh Ilango, Michelle Gill, Florian Meier, Sander Willems & Matthias Mann | Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | 200 SPD | Bruker timsTOF Pro | 200-spd | timstof-pro | |
Neat plasma proteomics: getting the best out of the worst | Publication | 2024 | Ines Metatla, Kevin Roger, Cerina Chhuon, Sara Ceccacci, Manuel Chapelle, Pierre-Olivier Schmit, Vadim Demichev & Ida Chiara Guerrera | Proteomics Platform Necker, Université Paris Cité-Structure Fédérative de Recherche Necker, Paris, France | 100 SPD, 60 SPD, Whisper 40 SPD | Bruker timsTOF Pro | 100-spd 60-spd whisper-40spd | timstof-pro | |
Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates | Publication | 2024 | Tilman Werner, Agnes Schäfer, Michael Hennes, Miguel Cosenza Contreras, Guadalupe Espadas, Eduard Sabido, Lena Cook, Axel Pagenstecher, Niko Pinter, Tobias Feilen, Alexander Grote, Christopher Nimsky, Jörg Walter Bartsch, Oliver Schilling | Institute for Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Structure and interactions of the endogenous human Commander complex | Publication | 2024 | Saara Laulumaa, Esa-Pekka Kumpula, Juha T. Huiskonen & Markku Varjosalo | Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Universal pretreatment development for low-input proteomics using lauryl maltose neopentyl glycol | Journal article | 2024 | Ryo Konno, Masaki Ishikawa, Daisuke Nakajima, Yusuke Endo, Osamu Ohara, Yusuke Kawashima | Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan | Whisper 80 SPD | Thermo Orbitrap Exploris 480 | whisper-80-spd | thermo-orbitrap-exploris-480 | |
Phosphoproteomic Analysis and Organotypic Cultures for the Study of Signaling Pathways | Publication | 2024 | Zilu Ye, Hans H. Wandall, and Sally Dabelsteen | Copenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
TIMAHAC: Streamlined Tandem IMAC-HILIC Workflow for Simultaneous and High-Throughput Plant Phosphoproteomics and N-glycoproteomics | Publication | 2024 | Chin-Wen Chen, Pei-Yi Lin, Ying-Mi Lai, Miao-Hsia Lin, Shu-Yu Lin, ChuanChih Hsu | Institution of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Polydopamine nanoparticles as a non-pharmaceutical tool in the treatment of fatty liver disease | Publication | 2024 | Alessio Carmignani, Matteo Battaglini, Martina Bartolucci, Andrea Petretto, Mirko Prato, Gianni Ciofani | Istituto Italiano di Tecnologia, Smart Bio-Interfaces, Pontedera, Italy | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
diaPASEF Enables High-throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development | Publication | 2024 | Taku Tsukidate, Alyssa Q. Stiving, Shannon Rivera, Ansuman Sahoo, Sri Madabhushi, Xuanwen Li | Analytical Research & Development Mass Spectrometry, New Jersey, United States | 100 SPD, 15 SPD, 30 SPD | Bruker timsTOF Pro 2 | 100-spd 15-spd 30-spd | timstof-pro-2 | |
SARS-CoV-2 Infection and Anemia—A Focus on RBC Deformability and Membrane Proteomics—Integrated Observational Prospective Study | Publication | 2024 | Angelo D’Alessandro, Elena Krisnevskaya, Valentina Leguizamon,Ines Hernández, Carolina de la Torre, Joan-Josep Bech, Josep-Tomàs Navarro and Joan-Lluis Vives-Corrons | Medical Campus, University of Colorado Anschutz, Aurora, USA | Thermo Orbitrap Eclipse Tribid | thermo-orbitrap-eclipse-tribid | |||
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons | Publication | 2024 | Linda Makhlouf, Joshua J. Peter, Helge M. Magnussen, Rohan Thakur, David Millrine, Thomas C. Minshull, Grace Harrison, Joby Varghese, Frederic Lamoliatte, Martina Foglizzo, Thomas Macartney, Antonio N. Calabrese, Elton Zeqiraj & Yogesh Kulathu | MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, UK | 30 SPD | Thermo Orbitrap Eclipse Tribid | 30-spd | thermo-orbitrap-eclipse-tribid | |
Automated high-throughput biological sex identification from archaeological human dental enamel using targeted proteomics | Publication | 2024 | Palesa P. Madupe, Gaudry B. Troché, Nuno Vibe Hermann, Marina Martínez de Pinillos, María MartinónTorres, Sandra Mularczyk, Marie Louise Schjellerup Jørkov, Christopher Gerner,Fabian Kanz, Ana Martinez-Val1, Enrico Cappellini, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty ofHealth and Medical Sciences, University of Copenhagen, Denmark. | 200 SPD, 30 SPD | Thermo Orbitrap Exploris 480 | 200-spd 30-spd | thermo-orbitrap-exploris-480 | |
The Proteome of Extracellular Vesicles Released from Pulmonary Microvascular Endothelium Reveals Impact of Oxygen Conditions on Biotrauma | Publication | 2024 | Wolfgang Schaubmayr, Beatrix Hochreiter, Eva Hunyadi-Gulyas, Louise Riegler, Katy Schmidt, Akos Tiboldi, Bernhard Moses, Klaus U. Klein, Katharina Krenn, Gisela Scharbert, Thomas Mohr, Johannes A. Schmid, Andreas Spittler,and Verena Tretter | Department of Anesthesia, General Intensive Care and Pain Medicine, Medical University of Vienna, Austria | 15 SPD | Thermo Orbitrap Fusion Lumos | 15-spd | thermo-orbitrap-fusion-lumos | |
PU.1 Eviction at Lymphocyte-Specific Chromatin Domains Mediates Glucocorticoid Response in Acute Lymphoblastic Leukemia | Publication | 2024 | Yizhou Huang, Han Zhao, Xiaolu Tai, Wenqian Xu, Hansen Kosasih, David Kealy, Katherine Bridge, Weiye Zhao, Andrew Holding, Adam Dowle, Samuel Taylor, Gaoxian Song, Diego Fajardo, Yashna Walia, Meng Wang, Chao Zhang, Jin Wang, Jian-Qing Mi | State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai | 100 SPD | Bruker timsTOF HT | 100-spd | bruker-timstof-ht | |
Targeting cancer-derived extracellular vesicles by combining CD147 inhibition with tissue factor pathway inhibitor for the management of urothelial cancer cells | Publication | 2024 | Vijay Kumar Boddu, Piet Zamzow, Mario Wolfgang Kramer, Axel S. Merseburger, Sivahari Prasad Gorantla, Matthias Klinger, Lena Cramer, Thorben Sauer, Timo Gemoll, Nikolas von Bubnoff, Frank Gieseler & Masoud Darabi | Department of Hematology and Oncology, Section for Experimental Oncology, University Hospital Schleswig-Holstein, Lübeck, Germany | 15 SPD, Extended method | 15-spd extended-method | |||
Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems | Publication | 2024 | Ana Blanco-Doval, Mikel Azkargorta, Ibon Iloro, Jabier Beaskoetxea, Felix Elortza, Luis Javier R. Barron, Noelia Aldai | Lactiker Research Group, Department of Pharmacy and Food Sciences, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
DYRKP kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression | Publication | 2024 | Minjae Kim, Gabriel Lemes Jorge, Moritz Aschern, Stéphan Cuiné, Marie Bertrand,Malika Mekhalfi, Jae-Seong Yang, Jay J. Thelen, Fred Beisson, Gilles Peltier, and Yonghua Li-Beisson | CEA, CNRS, Aix-Marseille University, Institute of Biosciences and Biotechnologies of Aix9 Marseille (BIAM),Saint-Paul-lez-Durance, France | Bruker timsTOF Pro 2 | timstof-pro-2 | |||
Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes | Publication | 2024 | Jeppe Kjærgaard Larsen, Ben Stocks, John Henderson, Daniel Andersson, Jesper Bäckdah, Daniel Eriksson-Hogling, Jacob V. Stidsen, Kei Sakamoto, Kurt Højlund, Mikael Rydén, Juleen R. Zierath, Anna Krook, Atul S. Deshmukh | Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
STREAMLINED PROTEOME-WIDE IDENTIFICATION OF DRUG TARGETS INDICATES ORGAN-SPECIFIC ENGAGEMENT | Publication | 2024 | Tanveer Singh Batth, Marie Locard-Paulet, Nadezhda T. Doncheva, Blanca Lopez Mendez, Lars Juhl Jensen, and Jesper Velgaard Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Phosphoproteomic investigation of targets of protein phosphatases in EGFR signaling | Publication | 2024 | Akihiro Eguchi, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF | Publication | 2024 | Charlotte Adams, Wassim Gabriel, Kris Laukens, Mario Picciani, Mathias Wilhelm, Wout Bittremieux, Kurt Boonen | Department of Computer Science, University of Antwerp, Antwerp, Belgium | 100 SPD | Bruker timsTOF Pro | 100-spd | timstof-pro | |
Proximity labeling proteomics reveals Kv1.3 potassium channel immune interactors in microglia | Publication | 2024 | Christine A. Bowen, Hai M. Nguyen, Young Lin, Pritha Bagchi, Aditya Natu, Claudia Espinosa-Garcia, Erica Werner, Prateek Kumar, Brendan R. Tobin, Levi Wood, Victor Faundez, Heike Wulff, Nicholas T. Seyfried, Srikant Rangaraju | Center for Neurodegenerative Diseases, Emory University, Atlanta, GA, USA | 15 SPD, 30 SPD | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | 15-spd 30-spd | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition | Publication | 2024 | Amelia C. Peterson, Florian Harking, Ole Østergaard, Rasmus Rydbirk, Susana Aznar, Hamish Stewart, Yue Xuan, Daniel Hermanson, Stevan Horning, Christian Hock, Alexander Makarov, Vlad Zabrouskov & Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue | Publication | 2024 | Rune Daucke, Charlotte V. Rift, Nicolai S. Bager, Kartikey Saxena, Peter R. Koffeldt, Jakob Woessmann, Valdemaras Petrosius, Eric Santoni-Rugiu, Bjarne W. kristensen, Pia Klausen & Erwin M. Schoof | Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Homo sapiens reached the higher latitudes of Europe by 45,000 years ago | Publication | 2024 | Michael Hein, Sahra Talamo, Lukas Wacker, Harald Meller, Holger Dietl, Jörg Orschiedt, Jesper V. Olsen, Hugo Zeberg, Kay Prüfer, Johannes Krause, Matthias Meyer, Frido Welker, Shannon P. McPherron, Tim Schüler & Jean-Jacques Hublin | Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany | 200 SPD | Thermo Orbitrap Exploris 480 | 200-spd | thermo-orbitrap-exploris-480 | |
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells | Publication | 2024 | Min Qiao, Carmen Van der Zwaan, Maria Giustina Rotordam,Thomas John, Laura Hertz, Arjan J. Hoogendijk, Nadine Becker, Christian Wagner, Marieke Von Lindern, Stephane Egee, Emile Van den Akker and Lars Kaestner | Theoretical Medicine and Biosciences, Campus University Hospital, Saarland University, Homburg, Germany | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Activity-Guided Proteomic Profiling of Proteasomes Uncovers a Variety of Active (And Inactive) Proteasome Species | Publication | 2024 | Manisha Priyadarsini Sahoo, Tali Lavy, Noam Cohen, Indrajit Sahu & Oded Kleifeld | Faculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel | Thermo Orbitrap Exploris 480, Thermo Q Exactive HF | thermo-orbitrap-exploris-480 thermo-q-exactive-hf | |||
The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 sub-strates in Mycobacterium marinum | Publication | 2024 | Bradley S. Jones, Daniel D. Hu, Kathleen R. Nicholson, Rachel M. Cronin, Matthew M. Champion and Patricia A. Champion | Department of Biological Sciences, Eck Institute for Global Health, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, United States | 15 SPD | Bruker timsTOF Pro | 15-spd | timstof-pro | |
Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis | Publication | 2024 | Shuai Zheng, Ouda Khammy, Lise Charlotte Marie Noack, Andreas De Meyer, Ghazanfar Abbas Khan, Nancy De Winne, Dominique Eeckhout, Daniel van Damme, Staffan Persson | Copenhagen Plant Science Center, Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
A macroevolution-inspired approach to reveal novel antibiotic resistance mechanisms | Publication | 2024 | Luiz Pedro de Carvalho, Fernanda Subtil, Teresa Machado, Holly Douglas, Joanna Kirkpatrick, Mark Skehel & Acely Garza-Garcia | The Herbert Wertheim UF Scripps Institute, FL, United States | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms | Publication | 2024 | Kieran Wynne, Carrie E. Bearden, Scott W. Woods, Barbara Cornblatt, Daniel Mathalon, William Stone, Tyrone D. Cannon, Jean Addington, Kristin S. Cadenhead, Diana Perkins, Clark Jeffries, David Cotter | Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland | Bruker timsTOF Pro | timstof-pro | |||
Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis | Publication | 2024 | Cory M. Willis, Luca Peruzzotti-Jametti, Valentina Fossati, Frank Edenhofer, Tommaso Leonardi, Christian Frezza, Irina Mohorianu, Angelo D’Alessandro, and Stefano Pluchino | Department of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK | Bruker timsTOF Pro | timstof-pro | |||
Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study | Publication | 2024 | Carrie E Bearden, Kristin S Cadenhead, Jean Addington, Elaine F Walker, Tyrone D Cannon, Mary Cannon, Pat McGorry, Paul Amminger, Gerard Cagney, Barnaby Nelson, Clark Jeffries, Diana Perkins, David R Cotter | Department of Psychiatry, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin, Ireland | Bruker timsTOF Pro | timstof-pro | |||
Plasma Proteomic Analysis Based on 4D-DIA Evaluates the Clinical Response to Imrecoxib in the Early Treatment of Osteoarthritis | Publication | 2024 | López-Gómez J, Villareal L, Andrés M, Ponte I, Xicoy B, Zamora L, Vilaseca M, Roque A | Biochemistry and Molecular Biology Department, Biosciences Faculty. Universitat Autònoma de Barcelona, Spain | 15 SPD | Thermo Orbitrap Eclipse Tribid, Thermo Orbitrap Lumos | 15-spd | thermo-orbitrap-eclipse-tribid thermo-orbitrap-lumos | |
Mechanism of chaperone coordination during cotranslational protein folding in bacteria | Publication | 2024 | Alžběta Roeselová, Sarah L. Maslen, Santosh Shivakumaraswamy, Grant A. Pellowe, Steven Howell, Dhira Joshi, Joanna Redmond, Svend Kjaer, J. Mark Skehel and David Balchin | Protein Biogenesis Laboratory, The Francis Crick Institute, London, UK | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients | Publication | 2024 | Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R. Ferrone, Lei Zheng, Jason H. Moore, Warren Tourtellotte, Jennifer E. Van Eyk & Dan Theodorescu | Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications | Publication | 2024 | Claudia Ctortecka, Natalie M. Clark, Brian Boyle, Anjali Seth, D. R. Mani, Namrata D. Udeshi & Steven A. Carr | Broad Institute of MIT and Harvard, Cambridge, MA, USA | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
The CDK Pho85 inhibits Whi7 Start repressor to promote cell cycle entry in budding yeast | Publication | 2024 | Cristina Ros-Carrero, Mihai Spiridon-Bodi, J Carlos Igual and Mercè Gomar-Alba | Institut de Biotecnologia i Biomedicina (BIOTECMED) and Departament de Bioquímica i Biologia Molecula rUniversitat de València, Burjassot Spain | Bruker timsTOF fleX | bruker-timstof-flex | |||
Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis | Publication | 2024 | Fredrik Leo, Rolf Lood, Kristina A. Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes Wickström | Department of Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden | Whisper 20 SPD | Thermo Q Exactive HF-X | whisper-20spd | thermo-q-exactive-hf-x | |
The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum | Publication | 2024 | Bradley S. Jones, Daniel D. Hu, Kathleen R. Nicholson, Rachel M. Cronin, Matthew M. Champion, and Patricia A. Champion | Department of Biological Sciences, Eck Institute for Global Health, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana | 15 SPD | Bruker timsTOF Pro | 15-spd | timstof-pro | |
Proteomics of colorectal tumors identifies the role of CAVIN1 in tumor formation and progression | Publication | 2024 | Jesper Olsen, Ana Martinez-Val, Leander van der Hoeven, Dorte Bekker-Jensen, Margarita Jørgensen, Jesper Nors, Giulia Franciosa, Claus Andersen, Jesper Bramsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
timsTOF HT Improves Protein Identification and Quantitative Reproducibility for Deep Unbiased Plasma Protein Biomarker Discovery | Publication | 2024 | Chinmay Belthangady, John Blume, Jessica K. Chan, Guillermo Flores-Campuzano, Yuntao Hu, Manway Liu, Mark A. Marispini, Megan G. Mora, Saividya Ramaswamy, Purva Ranjan, Preston B. Williams, Robert J. X. Zawada, Philip Ma, and Bruce E. Wilcox | PrognomiQ Inc., San Mateo, California, United States | 100 SPD, 30 SPD, 60 SPD | Bruker timsTOF HT, Bruker timsTOF Pro 2 | 100-spd 30-spd 60-spd | bruker-timstof-ht timstof-pro-2 | |
Kinase inhibitor pulldown assay (KiP) for clinical proteomics | Publication | 2024 | Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA | Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients | Publication | 2024 | Marc Vervuurt, Joseph M. Schrader, Anna M. de Kort, Iris Kersten, Hans J. C. T. Wessels, Catharina J. M. Klijn, Floris H. B. M. Schreuder, H. Bea Kuiperij, Jolein Gloerich, William E. Van Nostrand & Marcel M. Verbeek | Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, 830 TML, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis | Publication | 2024 | Sophia Steigerwald, Ankit Sinha, Kyle L. Fort, Wen-Feng Zeng, Lili Niu, Christoph Wichmann, Arne Kreutzmann, Daniel Mourad, Konstantin Aizikov, Dmitry Grinfeld, Alexander Makarov, Matthias Mann, Florian Meier | Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | 100 SPD, 200 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 100-spd 200-spd 60-spd | thermo-orbitrap-exploris-480 | |
Multi-omics profiling with untargeted proteomics for blood-based early detection of lung cancer | Publication | 2024 | Madhuvanthi Ramaiah, Saividya Ramaswamy, Purva Ranjan, Guanhua Shu, Peter Spiro, Benjamin Ta, Dijana Vitko, Jacob Waiss, Zachary Yanagihara, Robert Zawada, Jimmy Yi Zeng, Susan Zhang, James Yee, John E. Blume, Chinmay Belthangady, Bruce Wilcox, Philip Ma | PrognomiQ, Inc., San Mateo, CA, USA | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome | Publication | 2024 | Cristina Lorca, María Fernández-Rhodes, Jose Antonio Sánchez Milán, María Mulet, Félix Elortza, Alfredo Ramos-Miguel, Luis F. Callado, J. Javier Meana, Maria Mur, Iolanda Batalla, Elisabet Vilella, Aida Serra and Xavier Gallart-Palau | Biomedical Research Institute of Lleida Dr. Pifarré Foundation (IRBLLEIDA), Neuroscience Area, +Pec Proteomics Research Group (+PPRG), University Hospital Arnau de Vilanova,Lleida, Spain | 15 SPD | Bruker timsTOF Pro | 15-spd | timstof-pro | |
Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions | Publication | 2024 | Andrés Trávez, Carmen Tercero-Alcázar, Alejandro Correa-Sáez, María Jesús González-Rellán, Oriol A. Rangel-Zúñiga, Amaia Rodríguez, Antonio Membrives, Gema Frühbeck, Rubén Nogueiras, Marco A. Calzado, Rocío Guzmán-Ruiz & María M. Malagón | Department of Cell Biology, Physiology, and Immunology, Maimonides Institute for Biomedical Research of Córdoba (IMIBIC), University of Córdoba (UCO), Reina Sofía University Hospital (HURS), Córdoba, Spain | Bruker timsTOF fleX | bruker-timstof-flex | |||
FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy | Publication | 2024 | Vera A. van der Weijden, Maximilian Stötzel, Dhanur P. Iyer, Beatrix Fauler, Elzbieta Gralinska, Mohammed Shahraz, David Meierhofer, Martin Vingron, Steffen Rulands, Theodore Alexandrov, Thorsten Mielke & Aydan Bulut-Karslioglu | Stem Cell Chromatin Group, Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany | Whisper 40 SPD | Thermo Q Exactive HF | whisper-40spd | thermo-q-exactive-hf | |
Direct translation of incoming retroviral genomes | Publication | 2024 | Julia Köppke, Luise-Elektra Keller, Michelle Stuck, Nicolas D. Arnow, Norbert Bannert, Joerg Doellinger & Oya Cingöz | Robert Koch Institute, Department of Infectious Diseases, Unit of Sexually Transmitted Bacterial Pathogens and HIV, Berlin, Germany | 30 SPD | Bruker timsTOF HT | 30-spd | bruker-timstof-ht | |
Single cell proteomics by mass spectrometry reveals deep epigenetic insight and new targets of a class specific histone deacetylase inhibitor | Publication | 2024 | Benjamin C. Orsburn | The Department of Pharmacology and Molecular Sciences, the Johns Hopkins University School of Medicine, Baltimore, MD, USA | 100 SPD, 200 SPD, 30 SPD, 300 SPD, 500 SPD, 60 SPD | Bruker timsTOF SCP | 100-spd 200-spd 30-spd 300-spd 500-spd 60-spd | bruker-timstof-scp | |
Calcium carbonate polymorph selection in fish otoliths: A key role of phosphorylation of Starmaker-like protein | Publication | 2024 | Marta Kalka, Klaudia Bielak, Maciej Ptak, Jarosław Stolarski, Piotr Dobryszycki, Magdalena Wojtas | Wroclaw University of Science and Technology, Faculty of Chemistry, Department of Biochemistry, Molecular Biology and Biotechnology, Wrocław, Poland | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Trauma Induces Intravascular Hemolysis, Exacerbated by RBC Transfusion and Associated with Disrupted Arginine-Nitric Oxide Metabolism | Publication | 2024 | Ernest E. Moore, Angela Sauaia, Monika Dzieciatkowska, William Hallas, Otto Thielen, Margot DeBot, Alexis Cralley, Ian LaCroix, Christopher Erickson, Sanchayita Mitra, Anirban Banerjee, Kenneth Jones, and Kirk C. Hansen | University of Colorado Denver, School of Medicine, Department of Biochemistry and Molecular Genetics, Aurora, CO | Bruker timsTOF Pro | timstof-pro | |||
Paracrine cross-talk between human adipose tissue-derived endothelial cells and perivascular cells accelerates the endothelialization of an electrospun ionomeric polyurethane scaffold | Publication | 2023 | Jeremy A. Antonyshyn, Kate D. MacQuarrie, Meghan J. McFadden, Anthony O. Gramolini, Stefan O.P. Hofer, J. Paul Santerre | Institute of Biomedical Engineering, University of Toronto, Toronto, Canada | 15 SPD | Thermo Q Exactive Plus | 15-spd | thermo-q-exactive-plus | |
Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters | Publication | 2023 | Nicoll Zeballos, Natalia Comino, Daniel Andrés-Sanz, Javier Santiago-Arcos, Mikel Azkargorta, Felix Elortza, Eleftheria Diamanti, and Fernando López-Gallego | Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), San Sebastián, Spain | Bruker timsTOF Pro | timstof-pro | |||
Modeling the simultaneous dynamics of proteins in blood plasma and the cerebrospinal fluid in human in vivo | Publication | 2023 | Pierre Giroux, Jérôme Vialaret, Jana Kindermans, Audrey Gabelle, Luc Bauchet, Christophe Hirtz, Sylvain Lehmann, Jacques Colinge | Université de Montpellier, Montpellier, France | 60 SPD | Bruker timsTOF HT | 60-spd | bruker-timstof-ht | |
Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimen | Publication | 2023 | Alexander M. Bernhardt, Lisa Schweizer, Vincent Albrecht, Daniel Teupser, Axel Imhof, Bernhard Kuster, Stefan F. Lichtenthaler, Matthias Mann, Jürgen Cox, and Stefanie M. Hauck | Metabolomics and Proteomics Core (MPC), Helmholtz Zentrum München,German Research Center for Environmental Health (GmbH), Munich, Germany | 60 SPD | Bruker timsTOF Pro, Thermo Orbitrap Exploris 480, Thermo Orbitrap Fusion Lumos, Thermo Q Exactive HF, Thermo Q Exactive HF-X | 60-spd | timstof-pro thermo-orbitrap-exploris-480 thermo-orbitrap-fusion-lumos thermo-q-exactive-hf thermo-q-exactive-hf-x | |
Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function | Publication | 2023 | Lina Wang, Dube Dheeraj Prakashchand, Nicholas P. Boyer, Veronica M. Saia-Cereda, Kristen Branes-Guerrero, Donald P. Pizzo, Pritha Bagchi, V.S. Sundar, Yong Tang, Utpal Das, David A. Scott, Padmini Rangaman, Yuki Ogawa, Subhojit Roy | Department of Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, USA | 15 SPD | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | 15-spd | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response | Publication | 2023 | Erica Stevenson, Yiwen R. Chen, Nabora S. Reyes, Tien Peng, Michael A. Matthay, Michela Traglia, Alexander R. Pico, Daniel F. Jarosz, Abigail Buchwalter, Sina Ghaemmaghami, Danielle L. Swaney, Isha H. Jain | Institute of Cardiovascular Disease, Gladstone Institutes, San Francisco, CA, USA | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
A biotin targeting chimera (BioTAC) system to map small molecule interactomes in situ | Publication | 2023 | Andrew J. Tao, Jiewei Jiang, Gillian E. Gadbois, Pavitra Goyal, Bridget T. Boyle, Elizabeth J. Mumby, Samuel A. Myers, Justin G. English & Fleur M. Ferguson | Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Comparative proteomic analysis of human milk fat globules and paired membranes and mouse milk fat globules identifies core cellular systems contributing to mammary lipid trafficking and secretion | Publication | 2023 | Jayne F. Martin Carli, Monika Dzieciatkowska, Teri L. Hernandez, Jenifer Monks, James L. McManaman | Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States | Bruker timsTOF Pro | bruker-timstof-pro | |||
Cryopreservation of highly extended pig spermatozoa remodels its proteome and counteracts polyspermic fertilization in vitro | Publication | 2023 | Inmaculada Parrilla, Josep M. Cambra, Cristina Cuello, Heriberto Rodriguez-Martinez, Maria A. Gil, Emilio A. Martinez | Department of Medicine and Animal Surgery, International Excellence Campus for Higher Education and Research “Campus Mare Nostrum,”, University of Murcia, Murcia, Spain | 60 SPD | Bruker timsTOF fleX | 60-spd | bruker-timstof-flex | |
Proteomic comparison between non‐purified cerebrospinal fluid and cerebrospinal fluid‐derived extracellular vesicles from patients with Alzheimer’s, Parkinson’s and Lewy body dementia | Publication | 2023 | Yael Hirschberg, Natalia Valle‐Tamayo, Oriol Dols‐Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, and Inge Mertens | Health Unit, Flemish Institute for Technological Research (VITO), Mol Belgium | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Fully automated workflow for integrated sample digestion and Evotip loading enabling high-throughput clinical proteomics | Publication | 2023 | Anders H. Kverneland, Florian Harking, Joel Mario Vej-Nielsen, Magnus Huusfeldt, Dorte B. Bekker-Jensen, Inge Marie Svane, Nicolai Bache, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark | 100 SPD, 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 100-spd 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Immunopeptidomics in the Era of Single-Cell Proteomics | Publication | 2023 | Rupert L. Mayer and Karl Mechtler | Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria | Whisper 40 SPD | Bruker timsTOF SCP, Bruker timsTOF Ultra, Thermo Orbitrap Astral, Thermo Q Exactive HF | whisper-40spd | bruker-timstof-scp bruker-timstof-ultra thermo-orbitrap-astral thermo-q-exactive-hf | |
IMBAS-MS discovers organ-specific HLA peptide patterns in plasma | Publication | 2023 | Maria Wahle, Marvin Thielert, Maximilian Zwiebel, Patricia Skowronek, Wen-Feng Zeng, Matthias Mann | Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | 15 SPD, 30 SPD, 60 SPD, Whisper 40 SPD | Bruker timsTOF Ultra | 15-spd 30-spd 60-spd whisper-40spd | bruker-timstof-ultra | |
An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics | Publication | 2023 | Anuar Makhmut, Di Qin, David Hartlmayr, Anjali Seth, Fabian Coscia | Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Spatial Proteomics Group, Berlin, Germany | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
INPP5D regulates inflammasome activation in human microglia | Publication | 2023 | Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B. Fancher, Alina Sigalov, Courtney R. Benoit, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Vilas Menon & Tracy L. Young-Pearse | Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA | 60 SPD | Thermo Orbitrap Eclipse Tribid | 60-spd | thermo-orbitrap-eclipse-tribid | |
Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens | Publication | 2023 | Stephan Eckert, Stephan A. Müller, Stephan Breimann, Pieter Giesbertz, Alexander M. Bernhardt, Lisa Schweizer, Vincent Albrecht, Daniel Teupser, Axel Imhof, Bernhard Kuster, Stefan F. Lichtenthaler, Matthias Mann, Jürgen Cox, and Stefanie M. Hauck | Metabolomics and Proteomics Core (MPC), Helmholtz Zentrum München,German Research Center for Environmental Health (GmbH), Munich, Germany | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Novel Assay for Quantification of Free Light Chain (FLC) Dimers in Serum of Patients with Plasma Cell Dyscrasias | Publication | 2023 | Mariya Liyasova PhD, Michael Slade MDMSCI, Julie Fortier PhD, Ravi Vij MD MBA, Mark Fiala PhD, Liqiang Yang PhD, Bin Ma PhD | Rapid Novor Inc., Kitchener, Canada | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Diagnostic Utility of Proteogenomic Analysis for Inherited Bone Marrow Failure Syndrome | Publication | 2023 | Manabu Wakamatsu MDPhD, Hideki Muramatsu MD PhD, Hironori Sato MDPhD, Masaki Ishikawa, Daisuke Nakajima, Ryo Konno, Yusuke Kawashima, Motoharu Hamada MDPhD, Yusuke Okuno MD PhD, Osamu Ohara, Yoshiyuki Takahashi MD PhD | Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
High-throughput proteomics uncovers exercise training and type 2 diabetes–induced changes in human white adipose tissue | Publication | 2023 | Jeppe Kjærgaard Larsen, Rikke Kruse, Navid Sahebkhtiari, Roger Moreno-Justicia, Gerard Gomez Jorba, Maria H. Petersen, Martin E. De Almeida, Niels Ørtenblkad, Atul S. Deshmukh, Kurt Højlund | Steno Diabetes Center Odense, Odense University Hospital, Odense C, Denmark | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
High-throughput and scalable single cell proteomics identifies over 5000 proteins per cell | Publication | 2023 | Zilu Ye, Pierre Sabatier, Leander van der Hoeven, Teeradon Phlairaharn, David Hartlmayr, Fabiana Izaguirre, Anjali Seth, Hiren J. Joshi, Dorte B. Bekker-Jensen, Nicolai Bache, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark | Whisper 40 SPD, Whisper 80 SPD | Thermo Orbitrap Astral | whisper-40spd whisper-80-spd | thermo-orbitrap-astral | |
BioE3 identifies specific substrates of ubiquitin E3 ligases | Publication | 2023 | Orhi Barroso-Gomila, Laura Merino-Cacho, Veronica Muratore, Coralia Perez, Vincenzo Taibi, Elena Maspero, Mikel Azkargorta, Ibon Iloro, Fredrik Trulsson, Alfred C. O. Vertegaal, Ugo Mayor, Felix Elortza, Simona Polo, Rosa Barrio & James D. Sutherland | Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography–Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study | Publication | 2023 | Lin Li, Christopher J Lyon, Sylvia M LaCourse, Wenshu Zheng, Joshua Stern, Jaclyn N Escudero, Wilfred Bundi Murithi, Lilian Njagi, Grace John-Stewart, Thomas R Hawn, Videlis Nduba, Wael Abdelgaliel, Thomas Tombler, David Horne, Li Jiang, Tony Y Hu | Center for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, LA, United States | Thermo Altis triple quadrupole | thermo-altis-triple-quadrupole | |||
Mapping cardiac remodeling in chronic kidney disease | Publication | 2023 | Giulia Franciosa, Aurelien Dugourd, Julio Saez-Rodriguez, Sabine Neuss, Michael Lehrke, Peter Boor, Claudia Goettesch, Jesper V. Olsen, Thimoteus Speer, Tzong-Shi Lu, Kennth Lim, Jürgen Floege, Laura Denby, Ivan Costa, Rafael Kramann | Clinic for Renal and Hypertensive Disorders, Rheumatological and Immunological Disease, University Hospital of the RWTH Aachen, Aachen, Germany | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Systematic optimization of automated phosphopeptide enrichment for high-sensitivity phosphoproteomics | Publication | 2024 | Patricia Bortel, Ilaria Piga, Claire Koenig, Christopher Gerner, Ana Martinez del Val, Jesper V. Olsen | Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Austria | Whisper 40 SPD | Thermo Orbitrap Exploris 480 | whisper-40spd | thermo-orbitrap-exploris-480 | |
Deep topographic proteomics of a human brain tumour | Publication | 2023 | Simon Davis, Connor Scott, Janina Oetjen, Philip D. Charles, Benedikt M. Kessler, Olaf Ansorge & Roman Fischer | Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford | Whisper 40 SPD | Bruker timsTOF Pro | whisper-40spd | bruker-timstof-pro | |
Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model | Publication | 2023 | Marwa Almosailleakh, Sofia Bentivegna, Samuele Narcisi, Sébasitien J. Benquet, Linn Gillberg, Carmen P. Montaño-Almendras, Simonas Savickas, Erwin M. Schoof, Amelie Wegener, Hérve Luche, Henrik E. Jensen, Christophe Côme & Kirsten Grønbæk | Department of Hematology, Rigshospitalet, 2100 Copenhagen, Denmark | |||||
Instrumentation at the leading edge of proteomics | Publication | 2023 | Trenton M. Peters-Clarke, Joshua J. Coon, Nicholas M. Riley | Department of Chemistry, University of Washington, Seattle, WA, USA | |||||
The social and structural architecture of the yeast protein interactome | Publication | 2023 | André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau & Matthias Mann | Max-Planck Institute of Biochemistry, Martinsried, Germany | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer | Publication | 2023 | Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, and Emily E. Bosco | Early Oncology Research, Biologics Engineering and Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Sensitive and Specific Global Cell Surface N-Glycoproteomics Shows Profound Differences Between Glycosylation Sites and Subcellular Components | Publication | 2023 | Noortje de Haan, Ming Song, Oliver C. Grant, Zilu Ye, Fawzi Khoder Agha, Mikkel Koed Møller Aasted, Robert J. Woods, Sergey Y. Vakhrushev, and Hans H. Wandall | Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen, Denmark | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Dynamic extracellular proximal interaction profiling reveals Low-Density Lipoprotein Receptor as a new Epidermal Growth Factor signaling pathway component | Publication | 2023 | Rasha Al Mismar, Payman Samavarchi-Tehrani, Brendon Seale, Vesal Kasmaeifar, Claire E. Martin, Anne-Claude Gingras | Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health, Toronto, Canada | 30 SPD, 60 SPD | Bruker timsTOF Pro 2 | 30-spd 60-spd | timstof-pro-2 | |
Synaptic involvement of the human amygdala in Parkinson’s disease | Publication | 2023 | Sandra Villar-Conde, Veronica Astillero-Lopez, Melania Gonzalez-Rodriguez, Daniel Saiz-Sanchez, Alino Martinez-Marcos, Isabel Ubeda-Banon, Alicia Flores-Cuadrado | Neuroplasticity and Neurodegeneration Group, CRIB, Faculty of Medicine of Ciudad Real, University of Castilla-La Mancha (UCLM), Spain | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue | Publication | 2023 | Andrew G. Chambers, David C. Chain, Steve M. Sweet, Zifeng Song, Philip L. Martin, Matthew J. Ellis, Claire Rooney and Yeoun Jin Kim | Early Oncology, AstraZeneca, One MedImmune Way, Gaithersburg, MD 20878, USA | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification | Publication | 2023 | Florian S. Harking, Alberto J. Taurozzi, Zandra Fagernäs, Ricardo M. Godinho, Geoff M. Smith, Marcel Weiss, Tim Schüler, Shannon P. McPherron, Harald Meller, João Cascalheira, Nuno Bicho, Jesper V. Olsen, Jean-Jacques Hublin & Frido Welker | Globe Institute, University of Copenhagen, Copenhagen, Denmark | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism | Publication | 2023 | Ngoc Nguyen Lunde, Nimo Mukhtar Mohamud Osoble, Andrea Dalmao Fernandez, Alfreda S. Antobreh, Abbas Jafari, Sachin Singh, Tuula A. Nyman, Arild C. Rustan, Rigmor Solberg and G. Hege Thoresen | Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Norway | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus | Publication | 2023 | Nina Rostgaard, Markus Harboe Olsen, Sara Diana Lolansen, Nicolas Hernandez Nørager, Peter Plomgaard, Nanna MacAulay & Marianne Juhler | Department of Neurosurgery, The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
A chemoproteomic platform for selective deubiquitinase inhibitor discovery | Publication | 2023 | Rosa Cookson, Aini Vuorinen, Jonathan Pettinger, Cassandra R. Kennedy, Joanna M. Kirkpatrick, Rachel E. Peltier-Heap, Andrew Powell, Ambrosius P. Snijders, Mark Skehel, David House, Katrin Rittinger, and Jacob T. Bush | Crick-GSK Biomedical LinkLabs, GSK, Gunnels Wood Road, Stevenage, Hertfordshire, UK | 30 SPD, 60 SPD | Thermo Orbitrap Fusion Lumos | 30-spd 60-spd | thermo-orbitrap-fusion-lumos | |
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction | Publication | 2023 | Alejandro Marmolejo-Garza, Marina Trombetta-Lima, Asmaa Oun, Jasmijn Hunneman, Tingting Chen, Jari Koistinaho, Sarka Lehtonen, Arjan Kortholt, Justina C. Wolters, Barbara M. Bakker, Bart J. L. Eggen, Erik Boddeke & Amalia Dolga | Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Identification of Plasma Biomarkers from Rheumatoid Arthritis Patients Using an Optimized Sequential Window Acquisition of All THeoretical Mass Spectra (SWATH) Proteomics Workflow | Publication | 2023 | Liang Jin, Fei Wang, Xue Wang, Bohdan P. Harvey, Yingtao Bi, Chenqi Hu, Baoliang Cui, Anhdao T. Darcy, John W. Maull, Ben R. Phillips, Youngjae Kim, Gary J. Jenkins, Thierry R. Sornasse and Yu Tian | Research & Development, AbbVie, North Chicago, IL, USA | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3 | Publication | 2023 | Julie Elisabeth Heggelund, Saykat Das, Jorunn Stamnaes, Rasmus Iversen & Ludvig M. Sollid | KG Jebsen Coeliac Disease Research Centre, Institute of Clinical Medicine, University of Oslo, Norway | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Müller glial cells located in the peripheral retina are more susceptible to high pressure: implications for glaucoma | Publication | 2023 | Xandra Pereiro, Noelia Ruzafa, Mikel Azkargorta, Felix Elorza, Arantxa Acera, António Francisco Ambrósio, Ana Raquel Santiago, Elena Vecino | University of the Basque Country: Universidad del Pais Vasco | 60 SPD | Bruker timsTOF Pro | 60-spd | timstof-pro | |
Production in Nicotiana benthamiana of a thermotolerant glucose oxidase that shows enzybiotic activity against Escherichia coli and Staphylococcus aureus | Publication | 2023 | David Talens-Perales, María Nicolau-Sanus, Julia Marín-Navarro, Julio Polaina, José-Antonio Daròs | Institute of Molecular and Cellular Biology of Plants (Higher Council of Scientific Research-Universitat Politècnica de València), Valencia, Spain | 100 SPD | Bruker timsTOF fleX | 100-spd | bruker-timstof-flex | |
Postpartum defects in inflammatory response after gestational diabetes precede progression to type 2 diabetes: a nested case-control study within the SWIFT study | Publication | 2023 | Julie A.D. Van, Yihan Luo, Jayne S. Danska, Feihan Dai, Stacey E. Alexeeff, Erica P. Gunderson, Hannes Rost, Michael B. Wheeler | Department of Physiology, Faculty of Medicine, University of Toronto, Ontario, Canada | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization | Publication | 2023 | Juliana K. Ilmain, Sofya S. Perelman, Maria C. Panepinto, Irnov Irnov, Nicolas Coudray, Nora Samhadaneh, Alejandro Pironti, Beatrix Ueberheide, Damian C. Ekiert, Gira Bhabha, Victor J. Torres | Department of Microbiology, New York University Grossman School of Medicine, New York, USA | 15 SPD | Thermo Q Exactive HF | 15-spd | thermo-q-exactive-hf | |
Direct isolation of small extracellular vesicles from human blood using viscoelastic microfluidics | Publication | 2023 | Yingchao Meng, Yanan Zhang, Marcel Bühler, Shuchen Wang, Mohammad Asghari, Alessandra Stürchler, Bogdan Mateescu, Tobias Weiss, Stavros Stavrakis, Andrew J. Demello | Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Zürich, Switzerland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome | Publication | 2023 | Constantin Ammar, Sophia C. Mädler, Andreas Metousis, Patricia Skowronek, Maria Wahle, Katherine Madden, Janine Gote-Schniering, Anna Semenova, Herbert B. Schiller, Edwin Rodriguez, Thierry M. Nordmann, Andreas Mund & Matthias Mann | Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | 30 SPD, Whisper 40 SPD | Bruker timsTOF SCP | 30-spd whisper-40spd | bruker-timstof-scp | |
MassSpecPreppy—An end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications | Publication | 2023 | Alexander Reder, Christian Hentschker, Leif Steil, Manuela Gesell Salazar, Elke Hammer, Vishnu M. Dhople, Thomas Sura, Ulrike Lissner, Hannes Wolfgramm, Denise Dittmar, Marco Harms, Kristin Surmann, Uwe Völker, Stephan Michalik | Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Germany | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition | Publication | 2023 | Pedro Aragon-Fernandez, Nil Üresin, Gergo Kovacs, Teeradon Phlairaharn, Benjamin Furtwängler, Jeff Op De Beeck, Sarah L. Skovbakke, Steffen Goletz, Simon Francis Thomsen, Ulrich auf dem Keller, Kedar N. Natarajan, Bo T. Porse & Erwin M. Schoof | Department of Biotechnology and Biomedicine, Technical University of Denmark | Whisper 20 SPD, Whisper 40 SPD | whisper-20spd whisper-40spd | |||
Expanding the MAPPs Assay to Accommodate MHC-II Pan Receptors for Improved Predictability of Potential T Cell Epitopes | Publication | 2023 | Katharina Hartman, Guido Steiner, Michel Siegel, Cary M. Looney, Timothy P. Hickling, Katharine Bray-French, Sebastian Springer, Céline Marban-Doran, and Axel Ducret | Roche Pharma Research and Early Development, Roche Innovation Center Basel, Switzerland | Whisper 40 SPD | Bruker timsTOF Pro 2 | whisper-40spd | timstof-pro-2 | |
Exploring the benefits of differential mobility separation and SWATH data independent acquisition for complex proteomic sample analysis | Poster | 2023 | J.C.Yves Le Blanc, Eva Duchoslav, Lyle Burton, Steve Tate and Brad Schneider | SCIEX | 100 SPD, 200 SPD | SCIEX TripleTOF 6600 MS system | 100-spd 200-spd | sciex-tripletof-6600-ms-system | |
Heterogeneity of radial spokes structural components and associated enzymes in Tetrahymena cilia | Journal article | 2023 | Marta Bicka, Corbin Black, Avrin Ghanaeian, Ewa Joachimiak, Anna Osinka, Sumita Majhi, Anna Konopka, Ewa Bulska, Khanh Huy Bui, Dorota Wloga | Laboratory of Cytoskeleton and Cilia Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
A dynamic bias in chromatin protein deposition at G-quadruplex sites | Publication | 2023 | Thamar Jessurun Lobo, Deng Chen, Martijn R. H. Zwinderman, Peter M Lansdorp, Frank J. Dekker, Victor Guryev | European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Sex differences in brain protein expression and disease | Journal article | 2023 | Yue Liu, Ekaterina S. Gerasimov, Selina M. Vattathil, Jiaqi Liu, David J. Cutler, Michael P. Epstein, Gabriëlla A. M. Blokland, Madhav Thambisetty, Juan C. Troncoso, Duc M. Duong, David A. Bennett, Allan I. Levey, Nicholas T. Seyfried, Thomas S. Wingo | Department of Human Genetics,Goizueta Alzheimer’s Disease Center, Emory University School of Medicine, Atlanta, GA, USA | 60 SPD | Thermo Orbitrap Eclipse Tribid | 60-spd | thermo-orbitrap-eclipse-tribid | |
The potential of plasma HLA peptides beyond neoepitopes | Publication | 2023 | Maria Wahle, Marvin Thielert, Maximilian Zwiebel, Patricia Skowronek, Wen-Feng Zeng, Matthias Mann | Department Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | Whisper 40 SPD | Bruker timsTOF Ultra | whisper-40spd | bruker-timstof-ultra | |
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity | Journal article | 2023 | Samira Tabaei, Mohammad Reza Haghshenas, Ali Ariafar, Kambiz Gilany, Allan Stensballe, Shirin Farjadian, Abbas Ghaderi | Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran | 100 SPD | Bruker timsTOF Pro 2 | 100-spd | timstof-pro-2 | |
A micro-flow, high-pH, reversed-phase peptide fractionation and collection system for targeted and in-depth proteomics of low-abundance proteins in limiting samples | Journal article | 2023 | Marta Zurawska, Mark Basik, Adriana Aguilar-Mahecha, Michal Dadlez, Dominik Domanski | Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Proteogenomic analysis of chemo-refractory high- grade serous ovarian cancer | Journal article | 2023 | Jiayi Ji, Seungyeul Yoo, Chenwei Lin, Uliana J. Voytovich, Yajue Huang, Sun-Hee Lee, Lindsay Bergan, Travis D. Lorentzen, Mehdi Mesri, Henry Rodriguez, Andrew N. Hoofnagle, Zachary T. Herbert, Alexey I. Nesvizhskii, Bing Zhang | Lester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA | SCIEX QTRAP 6500 | sciex-qtrap-6500 | |||
MassSpecPreppy – an end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications | Publication | 2023 | Alexander Reder, Christian Hentschker, Leif Steil, Manuela Gesell Salazar, Elke Hammer, Vishnu M. Dhople, Thomas Sura, Ulrike Lissner, Hannes Wolfgramm, Denise Dittmar, Marco Harms, Kristin Surmann, Uwe Volker, Stephan Michalik | University Medicine Greifswald: Greifswald, DE | Bruker timsTOF Pro 2, Thermo Fisher Ultimate 3000, Thermo Orbitrap Exploris 480 | timstof-pro-2 thermo-fisher-ultimate-3000 thermo-orbitrap-exploris-480 | |||
Selective targeting of IL2Rbg combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC | Journal article | 2023 | Jacob Gadwa, Maria Amann, Thomas E. Bickett, Christian Klein, Angelo D’Alessandro, Sana D. Karam | Department of Radiation Oncology, University of Colorado, Anschutz Medical Campus, Aurora, USA | 15 SPD, 30 SPD | Bruker timsTOF Pro | 15-spd 30-spd | timstof-pro | |
Very early life microbiome and metabolome correlates with primary vaccination variability in children | Journal article | 2023 | Thomas P. Wyche, John Kang, Hendrik Wesseling, Begüm D. Topçuoğlu, Thomas Cairns, Theodore R. Sana, Robin M. Kaufhold, Julia M. Maritz, Christopher H. Woelk, Gokul Swaminathan, James E. Norton Jr., Michael E. Pichichero | Exploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts, USA | Whisper 40 SPD | Thermo Q Exactive HF-X | whisper-40spd | thermo-q-exactive-hf-x | |
Emergence of the Dickeya genus involved duplication of the OmpF porin and the adaptation of the EnvZ-OmpR signaling network | Journal article | 2023 | Clémence Cochard, Marine Caby, Peggy Gruau, Edwige Madec, Michael Marceau, Iulia Macavei, Jérôme Lemoine, Chrystelle Le Danvic, Franck Bouchart, Brigitte Delrue, Sébastien Bontemps-Gallo, Jean-Marie Lacroix | Univ. Lille, CNRS, UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, France | 60 SPD | SCIEX ZenoTOF 7600 | 60-spd | sciex-zenotof-7600 | |
Red Blood Cells from Individuals with Lesch–Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency | Journal article | 2023 | Julie A. Reisz, Monika Dzieciatkowska, Daniel Stephenson, Fabia Gamboni, D. Holmes Morton, Angelo D’Alessandro | Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, USA | Bruker timsTOF Pro | timstof-pro | |||
Deep and fast label-free Dynamic Organellar Mapping | Journal article | 2023 | Julia P. Schessner, Vincent Albrecht, Alexandra K. Davies, Pavel Sinitcyn, Georg H. H. Borner | Department of Proteomics and Signal Transduction, Systems Biology of Membrane Trafficking Research Group, Max-Planck Institute of Biochemistry, Martinsried, Germany | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver Diseases | Journal article | 2023 | Mar Gil, Mikel Azkargorta, Carla Fuster, María Martínez-Gómez, Imma Raurell, Aurora Barberá, Juan Manuel Pericàs, Diana Hide, Felix Elortza, Joan Genescà, María Martell | Liver Diseases, Vall d’Hebron Institut de Recerca (VHIR), Liver Unit, Hospital Universitari Vall d’Hebron (HUVH), Vall d’Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB) | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
An unconventional TOG domain is required for CLASP localization | Journal article | 2023 | Nelly Gareil, Alison Gervais, Nicolas Macaisne, Guillaume Chevreux, Julie C. Canman, Jessica Andreani, Julien Dumont | Université Paris Cité, CNRS, Institut Jacques Monod | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients | Publication | 2023 | Christopher B. Erickson, Ian S. Lacroix, Margot Debot, Monika Dzieciatkowska, Terry R. Schaid, Morgan W. Hallas, Otto N. Thielen, Alexis L. Cralley, Anirban Banerjee, Ernest E Moore, Christopher C. Silliman, Angelo D’Alessandro, Kirk C. Hansen | Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus; Aurora, CO | Bruker timsTOF Pro | timstof-pro | |||
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1 | Journal article | 2023 | Hyo Lee, Aimee J. Aylward, Richard V. Pearse II, Vilas Menon, Jessica E. Young, Tracy L. Young-Pearse | Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA | 60 SPD | Thermo Orbitrap Eclipse Tribid | 60-spd | thermo-orbitrap-eclipse-tribid | |
Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel | Journal article | 2023 | Lisa Schweizer, Thierry M Nordmann, Patricia Skowronek, Maria Wahle, Wen-Feng Zeng, Xie-Xuan Zhou, Andreas-David Brunner, Sabrina Richter, Mitchell P Levesque, Fabian J Theis, Martin Steger, Matthias Mann | Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | Whisper 40 SPD | Bruker timsTOF Pro | whisper-40spd | timstof-pro | |
Quantitative multiorgan proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation | Journal article | 2023 | Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes Bruno Müller-Reif,Wen-Feng Zeng, Sebastian Dintner, Thierry M Nordmann, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias Mann | Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae | Journal article | 2023 | Ulises H. Guzman, Henriette Aksnes, Rasmus Ree, Nicolai Krogh, Magnus E. Jakobsson, Lars J. Jensen, Thomas Arnesen, Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Enhanced CellWall and Cell Membrane Activity Promotes Heat | Journal article | 2023 | Li Wang, Aike Li, Jun Fang, Yongwei Wang, Lixian Chen, Lin Qiao, Weiwei Wang | Academy of National Food and Strategic Reserves Administration, College of Bioscience and Biotechnology, Hunan Agricultural University, China | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Mechanisms of nuclear pore complex disassembly by the mitotic Polo-like kinase 1 (PLK-1) in C. elegans embryos | Journal article | 2023 | Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer, Lionel Pintard | Université Paris Cité, CNRS, Institut Jacques Monod | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Effects of multiple stressors on pancreatic human islets proteome reveal new insights into the pathways involved | Journal article | 2023 | Mehari Muuz Weldemariam, Putty-Reddy Sudhir, Jongmin Woo, Qibin Zhang | Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, USA | 15 SPD | Thermo Orbitrap Exploris 240 | 15-spd | thermo-orbitrap-exploris-240 | |
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope | Journal article | 2023 | Paulina Gregorczyk, Natalia Porebska, Dominika Żukowska, Aleksandra Chorążewska, Aleksandra Gędaj, Agata Malinowska, Jacek Otlewski, Małgorzata Zakrzewska, Łukasz Opaliński | Faculty of Biotechnology, Department of Protein Engineering, University of Wroclaw | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol | Journal article | 2023 | Yuchuan Li, Manoj Amrutkar, Anette Vefferstad Finstadsveen, Knut Tomas Dalen, Caroline S Verbeke, Ivan P. Gladhaug | University of Oslo, Oslo University Hospital Rikshospitalet | 30 SPD | Bruker timsTOF | 30-spd | bruker-timstof | |
Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix | Publication | 2023 | Shweta Mahajan, Deepti Dabral, Britt Coenen, Frans Bianchi, Niek van Hilten, Herre Jelger Risselada, Wouter H. Roos, Jesper Olsen, Laia Querol Cano, Geert van den Bogaart | Department of Molecular Immunology, Groningen Biomolecular Sciences and Biotechnology | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Clinical proteomics reveals vulnerabilities in non-invasive breast ductal carcinoma and drives personalized treatment strategies | Publication | 2023 | Georgia Mitsa, Livia Florianova, Josiane Lafleur, Adriana Aguilar-Mahecha, Rene P. Zahedi, Sonia V del Rincon, Mark Basik, Christoph H Borchers, Gerald Batist | Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC | Extended method | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | extended-method | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
A seven-transmembrane methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases | Journal article | 2023 | Tanveer S. Batth, Jonas L. Simonsen, Cristina Hernández-Rollán, Søren Brander, Jens Preben Morth, Katja S. Johansen, Morten H. H. Nørholm, Jakob B. Hoof & Jesper V. Olsen | The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Protocol for high-throughput semi-automated label-free- or TMT-based phosphoproteome profiling | Publication | 2023 | Claire Koenig, Ana Martinez-Val, Previn Naicker, Stoyan Stoychev, Justin Jordaan, Jesper V. Olsen | Evosep Biosystems, Odense, Denmark, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ReSyn Biosciences, Pretoria, South Africa | 30 SPD, 60 SPD, Whisper 20 SPD, Whisper 40 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd whisper-20spd whisper-40spd | thermo-orbitrap-exploris-480 | |
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes | Publication | 2023 | Zilu Ye, Pierre Sabtier, Javier Martin-Gonzalez, Akihiro Eguchi, Dorte Bekker-Jensen, Nicolai Bache, Jesper V. Olsen | Denmark, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, Core Facility for Transgenic Mice, Department of Experimental Medicine, University of Copenhagen, Denmark | Whisper 40 SPD | Thermo Orbitrap Astral, Thermo Orbitrap Exploris 480 | whisper-40spd | thermo-orbitrap-astral thermo-orbitrap-exploris-480 | |
A complete and automated end-to-end sample preparation strategy for high-throughput and standardized proteomics with high sensitivity | Poster | 2023 | Magnus Huusfeldt, Joel Vej-Nielsen, Dorte B. Bekker-Jensen, Lasse Falkenby, Jesper V. Olsen, Nicolai Bache | Evosep Biosystems, Denmark, University of Copenhagen | 100 SPD, 30 SPD, Whisper 40 SPD | 100-spd 30-spd whisper-40spd | |||
Pushing the boundaries for robust and high-throughput single cell analysis with Whisper Flow technology powered by dia-PASEF | Poster | 2023 | Dorte B. Bekker-Jensen, Christoph Krisp, David Hartlmayr, Anjali Seth, Ole B. Hørning, Magnus Huusfeldt, Andreia Almeida, Markus Lubeck, Gary Kruppa, Jarrod Sandow & Nicolai Bache | Evosep Biosystems, Bruker Daltonics GmBH & Co. KG, Cellenion, IonOpticks, Bruker s.r.o | Whisper 40 SPD, Whisper 80 SPD | Bruker timsTOF SCP | whisper-40spd whisper-80-spd | bruker-timstof-scp | |
Rapid and robust PTM peptide mapping for biologics with the Evosep One and the ZenoTOF 7600 | Poster | 2023 | Moritz Heusel, Stephen Lock, Nick Morrice, Sibylle Heidelberger, Jakob Bunkenborg, Michael Barrett Andersen, Nicolai Bache | Evosep Biosystems, SCIEX Macclesfield | 100 SPD, 200 SPD, 300 SPD, 60 SPD | SCIEX ZenoTOF 7600 | 100-spd 200-spd 300-spd 60-spd | sciex-zenotof-7600 | |
A genetic code change in progress: tRNA-Leu(CAG) is conserved in most Saccharomycopsis yeast 3 species but is non-essential and does not compete with tRNA-Ser(CAG) in translation | Publication | 2023 | Eoin Ó Cinnéide, Caitriona Scaife, Eugene Dillon, Kenneth H. Wolfe | University College Dublin | 15 SPD | Bruker timsTOF Pro | 15-spd | bruker-timstof-pro | |
Distribution and Chemistry of Phoenixin-14, a Newly Discovered Sensory Transmission Molecule in Porcine Afferent Neurons | Journal article | 2023 | Urszula Mazur, Ewa Lepiarczyk, Paweł Janikiewicz, Elżbieta Łopieńska-Biernat, Mariusz Krzysztof Majewski and Agnieszka Bossowska | University of Warmia and Mazury in Olsztyn | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Altered intratumoral immune composition after Nivolumab treatment in patients with recurrent glioblastoma | Journal article | 2023 | Sine Hadrup, Signe Skadborg, Simone Maarup, Arianna Draghi, Annie Borch, Sille Hendriksen, Filip Mundt, Matthias Mann, Jane Skjoeth-Rasmussen, Christina Westmose Yde, Hans Poulsen, Benedikte Hasselbach, Inge Marie Svane | Technical University of Denmark, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Rigshospitalet | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for their function | Journal article | 2023 | Kai Liu, Ralf Nilsson, Elisa Lázaro-Ibáñez, Hanna Duàn, Tasso Miliotis, Marie Strimfors, Michael Lerche, Ana Rita Salgado Ribeiro, Johan Ulander, Daniel Lindén, Anna Salvati & Alan Sabirsh | AstraZeneca, University of Gothenburg | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins | Publication | 2023 | John Yates III, Ahrum Son, Hyunsoo Kim, Jolene Diedrich, Tom Bamberger, Daniel McClatchy | Scripps Research Institute, Chungnam National University | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF | Publication | 2023 | Zhi‑Qing Zhu, Tian Zhang, Shuo Chang, Zhen‑Hua Ren and Qin Zhang | First Affiliated Hospital of Anhui Medical University, Anhui Medical University | Bruker timsTOF | bruker-timstof | |||
Cross-Linking Mass Spectrometry on P-Glycoprotein | Journal article | 2023 | Gabriella Gellen, Eva Klement, Kipchumba Biwott, Gitta Schlosser,Gergő Kalló, Éva Csősz, Katalin F. Medzihradszky and Zsolt Bacso | ELTE Eötvös Loránd University, University of Debrecen, HCEMM, BRC | Extended method | Thermo Orbitrap Fusion Lumos | extended-method | thermo-orbitrap-fusion-lumos | |
Profiling of the Klebsiella pneumoniae Phosphoproteome under Iron-Limited and Iron-Replete Conditions | Journal article | 2023 | Chelsea Reitzel, Arjun Sukumaran, Benjamin Muselius, Siobhan O’Connor, Jennifer Geddes-McAlister | University of Guelph | Thermo Orbitrap Exploris 240 | thermo-orbitrap-exploris-240 | |||
Topological defects at smectic interfaces as a potential tool for the biosensing of living microorganisms | Publication | 2023 | Vajra S. Badha, Tagbo H.R. Niepa, and Mohamed Amine Gharbia | University of Massachusetts Boston, Carnegie Mellon University, | Bruker timsTOF HT | bruker-timstof-ht | |||
TIMSTOF Compass 4.0 Methods – LCMS and MALDI – OrsburnLab 2023 v1 | Publication | 2023 | Benjamin Orsburn | The Johns Hopkins University School of Medicine | Whisper 40 SPD | Bruker timsTOF | whisper-40spd | bruker-timstof | |
ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast | Publication | 2023 | Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska & Roza Kucharczyk | Polish Academy of Sciences | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
DIS3 ribonuclease prevents the cytoplasmic accumulation of lncRNAs carrying non-canonical ORFs, which represent a source of cancer immunopeptides | Journal article | 2023 | Dominika Foretek, Marc Gabriel, Isabelle Hatin, Julien Jarroux, Marina Pinskaya, Elise Pepermans, Kurt Boonen, Rachel Topno, Vera Slaninova, Marina Serna, Oscar Llorca, Geert Baggerman, Edouard Bertrand, Steven West, Olivier Namy | Institut Curie, Institute for Integrative Biology of the Cell, Weill Cornell Medicine, Institut Curie-CNRS, University of Antwerp, Institut Genetique Humaine, Spanish National Cancer Research Center (CNIO), Institut de Génétique Humaine, University of | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
The protein and miRNA profile of plasma extracellular vesicles (EVs) can distinguish feline mammary adenocarcinoma patients from healthy feline controls | Journal article | 2023 | Jane Howard, John Browne, Stephanie Bollard, Susan Peters, Ciara Sweeney, Kieran Wynne, Shirley Potter, Amanda McCann & Pamela Kelly | University College Dublin, Mater Misericordiae University Hospital | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Co-administration of angiotensin II and simvastatin triggers kidney injury upon heme oxygenase-1 deficiency | Publication | 2023 | Aleksandra Kopacz, Damian Kloska, Dominik Cysewski, Izabela Kraszewska, Karolina Przepiorska, Małgorzata Lenartowicz, Agnieszka Łoboda, Anna Grochot-Przęczek, Witold Nowak, Alicja Jozkowicz, and Aleksandra Piechota-Polanczyk | Jagiellonian University, Polish Academy of Sciences, and Białystok, | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Vacuum Insulated Probe Heated Electrospray Ionization Source Enhances Microflow Rate Chromatography Signals in the Bruker timsTOF Mass Spectrometer | Publication | 2023 | Mukul K. Midha, Charu Kapil, Michal Maes, David H. Baxter, Seamus R. Morrone, Timothy J. Prokop, and Robert L. Moritz | Institute for Systems Biology | 100 SPD, 15 SPD, 200 SPD, 30 SPD, 60 SPD | Bruker timsTOF | 100-spd 15-spd 200-spd 30-spd 60-spd | bruker-timstof | |
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b | Journal article | 2023 | Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, Klaudi | Center for Cooperative Research in Biosciences, NOVA School of Science and Technology, University of La Rioja, | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Evaluation of a ‘plug and play’ nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens | Journal article | 2023 | Georgia Mitsa, Vincent R Richard, Yasamin Majedi, Josiane Lafleur, Adriana Aguilar-Mahecha, Mark Basik, Christoph H Borchers | McGill University, Jewish General Hospital | 15 SPD | Thermo Q Exactive | 15-spd | thermo-q-exactive | |
More proteome coverage in a single experiment with the Extended method | Application note | 2023 | Evosep Biosystems | Extended method | extended-method | ||||
A specialized separation method for hydrophobic targets with the High Organic method | Application note | 2023 | Evosep Biosystems | High Organic Method | high-organic-method | ||||
A specialized method using Whisper Flow technology with a throughput of 20 samples per day | Application note | 2023 | Evosep Biosystems | Whisper 20 SPD | whisper-20spd | ||||
A specialized method using Whisper Flow technology with a throughput of 80 samples per day | Application note | 2023 | Evosep Biosystems | Whisper 80 SPD | whisper-80-spd | ||||
A standardized separation method with a throughput of 500 samples per day | Application note | 2023 | Evosep Biosystems | 500 SPD | 500-spd | ||||
A specialized method using Whisper Flow technology with a throughput of 40 samples per day | Application note | 2023 | Evosep Biosystems | Whisper 40 SPD | whisper-40spd | ||||
Evotip Pure simplifies workflows with excellent reproducibility, storage and recovery | Application note | 2023 | Evosep Biosystems | 100 SPD, 60 SPD, Whisper 40 SPD | 100-spd 60-spd whisper-40spd | ||||
Towards a Standardized Omics Platform with the 60 samples per day method | Application note | 2023 | Evosep | Evosep | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Towards a Standardized Omics Platform with the 100 samples per day method | Application note | 2023 | Evosep | Evosep | 100 SPD | Thermo Orbitrap Exploris 480 | 100-spd | thermo-orbitrap-exploris-480 | |
Towards a Standardized Omics Platform with the 200 samples per day method | Application note | 2023 | Evosep | Evosep | 200 SPD | Thermo Orbitrap Exploris 480 | 200-spd | thermo-orbitrap-exploris-480 | |
A standardized separation method with a throughput of 300 samples per day | Application note | 2023 | Evosep | Evosep | 300 SPD | Thermo Orbitrap Exploris 480 | 300-spd | thermo-orbitrap-exploris-480 | |
Evosep One solves the proteomics dilemma – covering high throughput analysis and proteome depth | Application note | 2023 | Evosep Biosystems | 100 SPD, 200 SPD, 30 SPD, 300 SPD, 60 SPD | 100-spd 200-spd 30-spd 300-spd 60-spd | ||||
End-to-end, fully automated digestion protocol and Evotip Pure workflow on the Opentrons OT-2 | Application note | 2023 | Evosep Biosystems | Evosep Biosystems | 100 SPD, Whisper 40 SPD | Bruker timsTOF Pro 2 | 100-spd whisper-40spd | timstof-pro-2 | |
Fully automated, rapid, robust sample loading on Evotip Pure with the Agilent AssayMAP Bravo | Application note | 2023 | Evosep Biosystems | Evosep Biosystems | 100 SPD, Whisper 40 SPD | Bruker timsTOF Pro 2, SCIEX ZenoTOF 7600 | 100-spd whisper-40spd | timstof-pro-2 sciex-zenotof-7600 | |
Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer | Publication | 2023 | Vanessa Ortiz-Barahona, Marta Soler, Veronica Davalos, Carlos A. García-Prieto, Maxime Janin, Fernando Setien, Irene Fernández-Rebollo, Joan J. Bech-Serra, Carolina De La Torre, Sonia Guil, Alberto Villanueva, Pei-Hong Zhang, Li Yang, Marco Guarnacci, Ulr | Josep Carreras Leukaemia Research Institute. Barcelona Supercomputing Center (BSC), Germans Trias i Pujol Health Science Research Institute, Bellvitge Biomedical Research Institute, University of Chinese Academy of Sciences, l, Fudan University and Shangh | 15 SPD | Thermo Orbitrap Eclipse Tribid | 15-spd | thermo-orbitrap-eclipse-tribid | |
Comprehensive proteomic characterization and functional annotation of Siberian sturgeon seminal plasma proteins | Journal article | 2023 | Natalia Kodzik, Andrzej Ciereszko, Mirosław Szczepkowski, Halina Karol, Sylwia Judycka, Agata Malinowska, Bianka Swiderska and Mariola A. Dietrich | Polish Academy of Sciences and Inland Fisheries Institute in Olsztyn | 15 SPD | Thermo Orbitrap Exploris 480 | 15-spd | thermo-orbitrap-exploris-480 | |
Brain molecular mechanisms in Rasmussen encephalitis | Publication | 2023 | Dominique F. Leitner, Ziyan Lin, Zacharia Sawaged, Evgeny Kanshin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Julia W. Chang, Gary W. Mathern, Jasper J. Anink, Eleonora Aronica, Thomas Wisniewski and Orrin Devinsky | NYU Grossman School of Medicine, University of California, University of Amsterdam and Epilepsy Institutes of the Netherlands Foundation | 15 SPD | Thermo Q Exactive HF-X | 15-spd | thermo-q-exactive-hf-x | |
Resolving the Temporal Splenic Proteome during Fungal Infection for Discovery of Putative Dual Perspective Biomarker Signatures | Journal article | 2023 | Benjamin Muselius, Florence Roux-Dalvai, Arnaud Droit and Jennifer Geddes-McAlister | University of Guelph, CHU de Québec - Université Laval Research Center and University of Guelph | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
In situ digestion of alcohol-fixed cells for quantitative proteomics | Publication | 2022 | Atsushi Hatano, Tomoyo Takami and Masaki Matsumoto | Graduate School of Medical and Dental Sciences and Niigata University | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins | Journal article | 2023 | David C. Nieman, Jongmin Woo, Camila A. Sakaguchi, Ashraf M. Omar, Yang Tang, Kierstin Davis, Alessandra Pecorelli, Giuseppe Valacchi and Qibin Zhang | Appalachian State University, University of North Carolina at Greensboro, North Carolina State University and University of Ferrara | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating | Journal article | 2023 | Andreia Cerqueira, Francisco Romero-Gavilán, Heike Helmholz, Mikel Azkargorta, Félix Elortza, Mariló Gurruchaga, Isabel Goñi, Regine Willumeit-Römer and Julio Suay | Universitat Jaume, Helmholtz-Zentrum Hereon Institute of Metallic Biomaterials, CIC bioGUNE and University of the Basque Country | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology | Journal article | 2023 | Filip Mundt, Annelaura Bach Nielsen, Josephine Kerzel Duel, Christina Westmose Yde, Martina Amnitzbøll Eriksen, Ulrik Lassen, Finn Cilius Nielsen, Kristoffer Rohrberg and Matthias Mann | University of Copenhagen, Novo Nordisk, Copenhagen University Hospital, Rigshospitalet and Max Planck Institute of Biochemistry | 30 SPD | Bruker timsTOF SCP | 30-spd | bruker-timstof-scp | |
Simultaneous targeting of PD-1 and IL-2Rbg with radiation therapy inhibits pancreatic cancer growth and metastasis | Publication | 2023 | Miles Piper, Maureen Hoen, Laurel B. Darragh, Michael W. Knitz, Diemmy Nguyen, Jacob Gadwa, Greta Durini, Idil Karakoc, Abby Grier, Brooke Neupert, Benjamin Van Court, Khalid N.M. Abdelazeem, Justin Yu, Nicholas A. Olimpo, Sophia Corbo, Richard Blake Ross | University of Colorado and Roche Innovation Center Zurich | Whisper 20 SPD | Bruker timsTOF SCP | whisper-20spd | bruker-timstof-scp | |
Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation | Publication | 2023 | Larisa Chernyaeva, Giorgio Ratti, Laura Teirilä, Satoshi Fudo, Uni Rankka, Anssi Pelkonen, Paula Korhonen, Katarzyna Leskinen, Salla Keskitalo, Kari Salokas, Christina Gkolfinopoulou, Katrina E Crompton, Matti Javanainen, Lotta Happonen, Markku Varjosalo, | University of Helsinki, University of Eastern Finland, National Center for Scientific Research "Demokritos", Newcastle University, Lund University and Kuopio University Hospital | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise | Publication | 2023 | Daniel T. Cervone, Roger Moreno-Justicia, Júlia Prats Quesada and Atul S. Deshmukh | University of Copenhagen | Bruker, SCIEX, Thermo | bruker sciex thermo | |||
Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer | Journal article | 2023 | V. Nieddu, V. Melocchi, C. Battistini, G. Franciosa, M. Lupia, C. Stellato, G. Bertalot, J. V. Olsen, N. Colombo, F. Bianchi and U. Cavallaro | European Institute of Oncology IRCSS, Fondazione IRCCS Casa Sollievo della Sofferenza, University of Copenhagen, APSS, University of Trento and University of Milan-Bicocca Centre for Medical Sciences – CISMed, taly University of Milan-Bicocca, ondazione I | 30 SPD | Thermo Q Exactive 480 | 30-spd | thermo-q-exactive-480 | |
A desert Chlorella sp. that thrives at extreme high-light intensities using a unique photoinhibition protection mechanism | Journal article | 2023 | Guy Levin, Michael Yasmin, Varda Liveanu, Carmit Burstein, Rawad Hanna, Oded Kleifeld, Marc C. Simanowitz, Ayala Meir, Yaakov Tadmor, Joseph Hirschberg, Noam Adir and Gadi Schuster | Technion, Hebrew University of Jerusalem & Newe Ya'ar Research Center | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
Characteristics of size-exclusion chromatography enriched porcine follicular fluid extracellular vesicles | Journal article | 2023 | Kinga Kaminska, Kasun Godakumara, Bianka Swiderska, Agata Malinowska, Getnet Midekessa, Kamila Sofinska, Jakub Barbasz, Alireza Fazeli and Malgorzata Grzesiak | Jagiellonian University, Estonian University of Life Sciences, University of Tartu, Polish Academy of Sciences, University of Sheffield | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project | Publication | 2023 | Maria Grazia Andreassi, Nadia Haddy, Mats Harms-Ringdahl, Jonica Campolo, Andrea Borghini, François Chevalier, Jochen M. Schwenk, Brice Fresneau, Stephanie Bolle, Manuel Fuentes and Siamak Haghdoost | CNR National Research Council Institute of Clinical Physiology, Université Paris-Saclay, Stockholm University, CEA-CNRS-ENSICAEN-University of Caen Normandy, Advanced Resource Center for HADrontherapy in Europe, SciLifeLab and University of Salamanca-CSIC | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
Flexibility, speed, and throughput for high proteome coverage using Zeno SWATH data-independent acquisition (DIA) coupled with the Evosep One system | Application note | 2023 | Patrick Pribil and Ihor Batruch | Sciex | 100 SPD, 200 SPD, 30 SPD, 300 SPD, 500 SPD, 60 SPD | Bruker timsTOF Pro 2, SCIEX ZenoTOF 7600 | 100-spd 200-spd 30-spd 300-spd 500-spd 60-spd | timstof-pro-2 sciex-zenotof-7600 | |
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells | Journal article | 2023 | Deepti Talwar, Colin G. Miller, Justus Grossmann, Lukasz Szyrwiel, Torsten Schwecke, Vadim Demichev, Ana-Matea Mikecin Drazic, Anand Mayakonda, Pavlo Lutsik, Carmen Veith, Michael D. Milsom, Karin Müller-Decker, Michael Mülleder, Markus Ralser & Tobias P | Nature Metabolism | 15 SPD | Bruker timsTOF Pro 2 | 15-spd | timstof-pro-2 | |
Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer’s Disease Mouse Model | Publication | 2023 | Evangelia Thanou, Frank Koopmans, Débora Pita-Illobre, Remco V. Klaassen,Berna Özer, Ioannis Charalampopoulos, August B. Smit, and Ka Wan Li | Amsterdam Neuroscience, University of Crete, Foundation for Research and Technology Hellas | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis | Publication | 2023 | Miles Piper, Maureen Hoen, Laurel B. Darragh, Michael W. Knitz, Diemmy Nguyen, Jacob Gadwa, Greta Durini, Idil Karakoc, Abby Grier, Brooke Neupert, Benjamin Van Court, Khalid N.M. Abdelazeem, Justin Yu, Nicholas A. Olimpo, Sophia Corbo, Richard Blake Ross | University of Colorado, University of Colorado | Whisper 20 SPD | Bruker timsTOF SCP | whisper-20spd | bruker-timstof-scp | |
Myosin inhibitor reverses hypertrophic cardiomyopathy in pediatric iPSC-cardiomyocytes to mirror variant correction | Publication | 2023 | Caroline Kinnear, Abdelrahman Said, Guoliang Meng, Yimu Zhao, Erika Y Wang, Neha Parmar, Wei Wei, Filio Billia, MD, Craig A Simmons, Milica Radisic, James Ellis, Seema Mital | The Hospital for Sick Children, University of Toronto, University Health Network, Massachusetts Institute of Technology, Ted Rogers Centre for Heart Research | 60 SPD | Thermo Orbitrap Fusion Lumos | 60-spd | thermo-orbitrap-fusion-lumos | |
Dynamic antagonism between key repressive pathways maintains the placental epigenome | Journal article | 2023 | Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Sim | Technische Universität Berlin, , Max Planck Institute for Molecular Genetics, Freie Universität Berlin, Karolinska Institutet, Max-Delbrück Center for Molecular Medicine, Universitätsklinikum Schleswig-Holstein Campus Kiel, Yale School of Medicine, Broad | 30 SPD | Bruker timsTOF SCP | 30-spd | bruker-timstof-scp | |
Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype | Journal article | 2023 | Miao Chen,Frank Koopmans, Iryna Paliukhovich,Sophie J. F. van der Spek, Jian Dong, August B. Smit, Ka Wan Li | Vrije Universiteit Amsterdam, Boston University | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Foresight in clinical proteomics: current status, ethical considerations, and future perspectives | Publication | 2023 | Filip Mundt, Nicolai J. Wewer Albrechtsen, Sebastian Porsdam Mann, Peter Treit, Medini Ghodgaonkar-Steger, Martina O’Flaherty, Reinout Raijmakers, Juan Antonio Vizcaíno, Albert J.R. Heck, Matthias Mann | University of Copenhagen, University of Oxford, Max Planck Institute of Biochemistry, Utrecht University, European Bioinformatics Institute (EMBL-EBI) | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Experimental strategies to improve drug-target identification in mass spectrometry-based thermal stability assays | Journal article | 2023 | Clifford G. Phaneuf, Konstantin Aizikov, Dmitry Grinfeld, Arne Kreutzmann, Daniel Mourad, Oliver Lange, Daniel Dai, Bailin Zhang, Alexei Belenky, Alexander A. Makarov & Alexander R. Ivanov | Northeastern University, Thermo Fisher Scientific, Disease Profiling and Functional Genomics, Tarmeta Biosciences | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Rapid Profiling of Protein Complex Reorganization in Perturbed Systems | Journal article | 2023 | Isabell Bludau, Charlotte Nicod, Claudia Martelli, Peng Xue, Moritz Heusel, Andrea Fossati, Federico Uliana, Fabian Frommelt, Ruedi Aebersold, and Ben C. Collins | ETH Zürich, Max Planck Institute of Biochemistry, Lund University, University of California San Francisco, Queen’s University of Belfast | 60 SPD | SCIEX TripleTOF 6600 MS system | 60-spd | sciex-tripletof-6600-ms-system | |
Towards a Standardized Omics Platform with the 30 samples per day method | Application note | 2023 | Evosep | Evosep | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics | Publication | 2023 | Arthur Viode, Patrick van Zalm, Kinga K. Smolen, Benoit Fatou, David Stevenson, Meenakshi Jha, Ofer Levy, Judith Steen and Hanno Steen | Boston Children's Hospital, Harvard Medical School, Maastricht University and Broad Institute of MIT and Harvard | 60 SPD | Bruker timsTOF Pro 2 | 60-spd | timstof-pro-2 | |
A Streamlined High-Throughput Plasma Proteomics Platform for Clinical Proteomics with Improved Proteome Coverage, Reproducibility, and Robustness | Publication | 2023 | Jongmin Woo and Qibin Zhang | University of North Carolina | 60 SPD | Thermo Orbitrap Exploris 240 | 60-spd | thermo-orbitrap-exploris-240 | |
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer’s disease risk gene SORL1 | Publication | 2023 | Hyo Lee, Aimee J. Aylward, Richard V. Pearse II, Yi-Chen Hsieh, Zachary M. Augur, Courtney R. Benoit, Vicky Chou, Allison Knupp, Cheryl Pan, Srilakshmi Goberdhan, Duc M. Duong, Nicholas T. Seyfried, David A. Bennett, Hans-Ulrich Klein, Philip L. De Jager, | Brigham and Women’s Hospital and Harvard Medical School, University of Washington, Emory School of Medicine, Rush University Medical Center & Columbia University Irving Medical Center | 60 SPD | Thermo Orbitrap Eclipse Tribid | 60-spd | thermo-orbitrap-eclipse-tribid | |
INPP5D/SHIP1 regulates inflammasome activation in human microglia | Publication | 2023 | Vicky Chou, Seeley B. Fancher, Richard V. Pearse II, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Phillip L. De Jager, Vilas Menon & Tracy L. Young-Pearse | Brigham and Women’s Hospital and Harvard Medical School, Columbia University Medical Center, Emory School of Medicine & Rush University Medical Center | 60 SPD | Thermo Orbitrap Eclipse Tribid | 60-spd | thermo-orbitrap-eclipse-tribid | |
DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes | Publication | 2023 | Fabian Frommelt, Andrea Fossati, Federico Uliana, Fabian Wendt, Xue Peng, Moritz Heusel, Bernd Wollscheid, Ruedi Aebersold, Rodolfo Ciuffa and Matthias Gstaiger | ETH Zurich, University of California San Francisco, J. David Gladstone Institutes, ETHZ Zurich & Evosep Biosystems | 60 SPD | Thermo Q Exactive 970 TM Plus Hybrid Quadrupole-Orbitrap | 60-spd | thermo-q-exactive-970-tm-plus-hybrid-quadrupole-orbitrap | |
Optimizing linear ion trap data independent acquisition towards single cell proteomics | Publication | 2023 | Teeradon Phlairaharn, Zilu Ye, Elena Krismer, Anna-Kathrine Pedersen, Maik Pietzner, Jesper V. Olsen, Erwin M. Schoof and Brian C. Searle | University of Copenhagen, Technical University of Munich, Germany, Berlin Institute of Health at Charité–Universitätsmedizin & The Ohio State University | Whisper 20 SPD, Whisper 40 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd whisper-40spd | thermo-orbitrap-eclipse-tribid | |
Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition | Publication | 2023 | Maarten P. Bebelman, Caitrin Crudden, Bart Snieder, Evangelia Thanou, Catharina J.M. Langedijk, Margarida Viola, Steven Eleonora, Urszula Baginska, Olaf Cotugno, Jan Paul M. Bebelman, Monique A.J. van Eijndhoven, Leontien Bosch, Ka Wan Li, Martine J. Smit | Vrije Universiteit Amsterdam, University Medical Center Utrecht, Université de Paris & Utrecht Universit | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Label-free single cell proteomics utilizing ultrafast LC and M Sinstrumentation: A valuable complementary technique to multiplexing | Publication | 2023 | Manuel Matzinger, Rupert L. Mayer & Kar l. Mechtler | Vienna BioCenter | Whisper 20 SPD, Whisper 40 SPD | whisper-20spd whisper-40spd | |||
Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo Like Kinase 1 (PLK-1) in C. elegans embryos | Publication | 2023 | Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Véronique Legros, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer and Lionel Pintard | Université Paris Cité, Programme équipe Labellisée Ligue contre le Cancer, Johns Hopkins University School of Medicine & CSIC/JA/Universidad Pablo de Olavide | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC | Publication | 2023 | Stephan Kamrad, Clara Correia-Melo, Lukasz Szyrwiel, Simran Kaur Aulakh, Jürg Bähler, Vadim Demichev, Michael Mülleder & Markus Ralser | Charité Universitätsmedizin Berlin, The Francis Crick Institute, University College London, University of Oxford & Max Planck Institute for Molecular Genetics | Extended method | Bruker timsTOF Pro 2 | extended-method | timstof-pro-2 | |
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1 | Publication | 2023 | Stephen Abini-Agbomson, Kristjan Gretarsson, Rochelle M. Shih, Laura Hsieh, Tracy Lou, Pablo De Ioannes, Nikita Vasilyev, Rachel Lee, Miao Wang, Matthew Simon, Jean-Paul Armache, Evgeny Nudler, Geeta Narlikar, Shixin Liu, Chao Lu & Karim-Jean Armache | New York University Grossman School of Medicine, Columbia University Irving Medical Center, The Rockefeller University, University of California, Howard Hughes Medical Institute, Yale University & Pennsylvania State University | Extended method | Thermo Orbitrap Fusion | extended-method | thermo-orbitrap-fusion | |
A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics | Publication | 2023 | Thierry M. Nordmann, Lisa Schweizer, Andreas Metousis, Marvin Thielert, Edwin Rodriguez, Lise Mette Rahbek-Gjerdrum, Pia-Charlotte Stadler, Michael Bzorek, Andreas Mund, Florian A. Rosenberger & Matthias Mann | Max Planck Institute of Biochemistry, Zealand University Hospital, LMU Munich & University of Copenhagen | Whisper 20 SPD | Bruker timsTOF SCP | whisper-20spd | bruker-timstof-scp | |
First trimester serum apolipoproteins in the prediction of late-onset preeclampsia | Publication | 2023 | Emma J. Bendix, Julie D. Ravn, Lene Sperling & Martin Overgaard | Odense University Hospital & University of Southern Denmark | 60 SPD | Thermo Altis triple quadrupole | 60-spd | thermo-altis-triple-quadrupole | |
An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices | Publication | 2023 | Martina Puzio, Niamh Moreton, Mairéad Sullivan, Caitriona Scaife, Jeffrey C. Glennon & John J. O’Connor | University College Dublin | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
No-stain protein labeling as a potential normalization marker for small extracellular vesicle proteins | Journal article | 2023 | Anjugam Paramanantham, Rahmat Asfiya, Siddharth Das, Grace McCully & Akhil Srivastava | University of Missouri School of Medicine | 30 SPD | Bruker timsTOF Pro 2 | 30-spd | timstof-pro-2 | |
Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome | Journal article | 2023 | Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock, Amiq Gazdhar, Gisela Kuhn, Peter Angel, Saverio Bellusci, Jürgen Brinckmann, Ulrich auf dem Keller, Sabine Werner and Mattia R. Bordoli | ETH Zurich, Technical University of Denmark, University of Lübeck, University Hospital Bern, German Cancer Research Center, German Lung Research Center & Universities of Giessen and Marburg Lung Center | 30 SPD | Thermo Q Exactive HF-X | 30-spd | thermo-q-exactive-hf-x | |
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19 | Journal article | 2023 | Gabriel Hirdman, Embla Bodén, Sven Kjellström, Carl‑Johan Fraenkel, Franziska Olm, Oskar Hallgren and Sandra Lindstedt | Lund University, Department of Infection Control Region Skåne and Skåne University Hospital | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast | Journal article | 2023 | Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska, Roza Kucharczyk | Polish Academy of Sciences | Thermo Orbitrap Exploris 480 | thermo-orbitrap-exploris-480 | |||
Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum | Journal article | 2023 | Fredrik Leo, Gunnel Svensäter, Rolf Lood, Claes Wickström | Malmö University, Genovis AB, Lund University | Thermo Q Exactive HF-X | thermo-q-exactive-hf-x | |||
Vacuum Insulated Probe Heated ElectroSpray Ionization source (VIP-HESI) enhances micro flow rate chromatography signals in the Bruker timsTOF mass spectrometer | Publication | 2023 | Mukul K. Midha, Charu Kapil, Michal Maes, David H. Baxter, Seamus R. Morrone, Timothy J. Prokop & Robert L. Moritz | Institute for Systems Biology | 100 SPD, 200 SPD, 30 SPD, 60 SPD, Extended method | Bruker timsTOF Pro | 100-spd 200-spd 30-spd 60-spd extended-method | bruker-timstof-pro | |
A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics | Publication | 2023 | Thierry M. Nordmann, Lisa Schweizer, Andreas Metousis, Marvin Thielert, EdwinRodriguez, Lise Mette Rahbek-Gjerdrum, Pia-Charlotte Stadler, Michael Bzorek, Andreas Mund, Florian A. Rosenberger & Matthias Mann | Max Planck Institute of Biochemistry, Zealand University Hospital, University Hospital Munich & University of Copenhagen | Whisper 20 SPD | Bruker timsTOF SCP | whisper-20spd | bruker-timstof-scp | |
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry | Journal article | 2023 | Pavan Baichan, Previn Naicker, Tanya Nadine Augustine, Martin Smith, Geofrey Candy, John Devar and Ekene Emmanuel Nweke | University of the Witwatersrand, Council for Scientifc and Industrial Research & Chris Hani-Baragwanath Academic Hospital | 60 SPD | SCIEX TripleTOF 6600 MS system | 60-spd | sciex-tripletof-6600-ms-system | |
Label-free single cell proteomics utilizing ultrafast LC and MS instrumentation: A valuable complementary technique to multiplexing | Journal article | 2023 | Manuel Matzinger, Rupert L. Mayer & Karl Mechtler | Vienna BioCenter | Whisper 20 SPD, Whisper 40 SPD | whisper-20spd whisper-40spd | |||
Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59 | Journal article | 2022 | Kieran Brennan, Katrine F. Iversen, Alfonso Blanco-Fernández, Thomas Lund, Torben Plesner and Margaret M. Mc Gee | University College Dublin, University of Southern Denmark & Odense University Hospital | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus | Publication | 2023 | Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker and John R Hepler | Emory University School of Medicine | Extended method | Thermo Q-Exactive Plus Hybrid Quadrupole-Orbitrap | extended-method | thermo-q-exactive-plus-hybrid-quadrupole-orbitrap | |
SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation | Journal article | 2023 | Solveig A. Krapf, Jenny Lund, Hege G. Bakke, Tuula A. Nyman, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen and Eili T. Kase | University of Oslo, Oslo University Hospital & AstraZeneca | Extended method | SCIEX TripleTOF 6600 MS system | extended-method | sciex-tripletof-6600-ms-system | |
Systematic Adaptation of Bacillus licheniformis to 2-Phenylethanol Stress | Journal article | 2023 | Yangyang Zhan,Haixia Xu, Hween Tong Tan, Ying Swan Ho, Dongxiao Yang, Shuwen Chen, Dave Siak-Wei Ow, Xin Lv, Fang Wei, Xuezhi Bi and Shouwen Chen | Hubei University, Bioprocessing Technology Institute (BTI) & Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences | 30 SPD | SCIEX TripleTOF 6600 MS system | 30-spd | sciex-tripletof-6600-ms-system | |
A chemoproteomic platform for reactive fragment profiling against the deubiquitinases | Publication | 2023 | Rosa Cookson, Aini Vuorinen, Jonathan Pettinger, Cassandra R. Kennedy, Joanna M. Kirkpatrick, Rachel E. Peltier-Heap, Andrew Powell, Ambrosius P. Snijders, Mark Skehel, David House, Katrin Rittinger and Jacob T. Bush | GSK & The Francis Crick Institute | 30 SPD, 60 SPD | Thermo Orbitrap Fusion Lumos | 30-spd 60-spd | thermo-orbitrap-fusion-lumos | |
BRM Complex in Arabidopsis Adopts ncBAF-like Composition and Requires BRD Subunits for Assembly and Stability | Journal article | 2023 | Paulina Stachula, Katarzyna Kapela, Ewelina Malecka, Kamila Jaronczyk, Jacek Patryn, Nina Siwirykow, Maria Bucholc, Malgorzata Marczak, Maciej Kotlinski and Rafal Archacki | University of Warsaw & Institute of Biochemistry and Biophysics PAS | Extended method | Thermo Orbitrap Exploris 480 | extended-method | thermo-orbitrap-exploris-480 | |
Exploiting Multi-Omics Profiling and Systems Biology to Investigate Functions of TOMM34 | Journal article | 2023 | Ekaterina V. Poverennaya, Mikhail A. Pyatnitskiy, Georgii V. Dolgalev, Viktoria A. Arzumanian, Olga I. Kiseleva, Ilya Yu. Kurbatov, Leonid K. Kurbatov, Igor V. Vakhrushev, Daniil D. Romashin, Yan S. Kim and Elena A. Ponomarenko | Institute of Biomedical Chemistry Moscow & Faculty Of Computer Science & National Research University Higher School of Economics Moscow | 30 SPD | Thermo Q Exactive | 30-spd | thermo-q-exactive | |
β-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited | Journal article | 2023 | Si Liu, Tanja Narancic, Jia‑Lynn Tham & Kevin E. O’Connor | University College Dublin | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Unique DUOX2+ACE2+ small cholangiocytes are pathogenic targets for primary biliary cholangitis | Publication | 2023 | Xi Li, Yan Li, Jintao Xiao, Huiwen Wang, Yan Guo, Xiuru Mao, Pan Shi, Yanliang Hou, Xiaoxun Zhang, Nan Zhao, Minghua Zheng, Yonghong He, Jingjing Ding, Ya Tan, Min Liao, Ling Li, Ying Peng, Xuan Li, Qiong Pan, Qiaoling Xie, Qiao Li, Jianwei Li, Ying Li, Z | Daping Hospital, Xiangya Hospital, Central South University, the First Affiliated Hospital of Wenzhou Medical University, ale University School of Medicine, | Bruker timsTOF | bruker-timstof | |||
Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling | Publication | 2023 | Laurent Lignieres, Nicolas Sénécaut, Tien Dang, Laura Bellutti, Marion Hamon, Samuel Terrier, Véronique Legros, Guillaume Chevreux, Gaëlle Lelandais, René-Marc Mege, Julien Dumont, and Jean-Michel Camadro | Université Paris Cité, Institut de Biologie Physico-Chimique, Institut de Biologie Physico-Chimique Véronique Legros, Guillaume Chevreux, Gaëlle Lelandais, René-Marc Mege, ̀ Julien Dumont,Institut de Biologie Physico-Chimique, Institut de Biologie Intégra | 30 SPD | Thermo Orbitrap Fusion | 30-spd | thermo-orbitrap-fusion | |
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer | Publication | 2023 | Antonela Merlotti, Benjamin Sadacca, Yago A. Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, | Université Paris Sciences et Lettres, Laboratory of Clinical immunology, Institute Mutualiste Montsouris, Dana-Farber Cancer Institute, Institut d’Investigacions Biomèdiques de Barcelona-CSIC, Dana-Farber Cancer Institute | Thermo Q Exactive | thermo-q-exactive | |||
Quantitative multi-organ proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation | Publication | 2023 | Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes B. Müller-Reif, Wen-Feng Zeng, Sebastian Dintner, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias Mann | Max-Planck Institute of Biochemistry, University Medical Center Augsburg, | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
PRMT5-mediated regulatory arginine methylation of RIPK3 | Publication | 2023 | Chanchal Chauhan, Ana Martinez-Val, Rainer Niedenthal, Jesper Velgaard Olsen, Alexey Kotlyarov, Simon Bekker-Jensen, Matthias Gaestel & Manoj B. Menon | Hannover Medical School, University of Copenhagen, Indian Institute of Technology Delhi | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Identification of Highly Sensitive Pleural Effusion Protein Biomarkers for Malignant Pleural Mesothelioma by Affinity-Based Quantitative Proteomics | Publication | 2023 | Nicolai B. Palstrøm, Martin Overgaard, Peter Licht , Hans C. Beck | Odense University Hospital, University of Southern Denmark, | 60 SPD | Thermo Altis triple quadrupole | 60-spd | thermo-altis-triple-quadrupole | |
Differential proteomic profile of lumbar and ventricular cerebrospinal fluid | Publication | 2023 | Nina Rostgaard, Markus Harboe Olsen, Maud Ottenheijm, Lylia Drici, Anja Hviid Simonsen, Peter Plomgaard, Hanne Gredal, Helle Harding Poulsen, Henrik Zetterberg, Kaj Blennow, Steen Gregers Hasselbalch, Nanna MacAulay, Marianne Juhler | Copenhagen University Hospital, University of Copenhagen, University of Gothenburg, | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Recent advances in the field of single-cell proteomics | Journal article | 2023 | Valdemaras Petrosius and Erwin M. Schoof | Technical University of Denmark | Whisper 20 SPD, Whisper 40 SPD | whisper-20spd whisper-40spd | |||
Comparative proteome and transcriptome analyses of the response of postharvest pears to Penicillium expansum infection | Journal article | 2023 | Meiqiu Xu, Esa Abiso Godana, Solairaj Dhanasekaran, Xiaoyun Zhang, Qiya Yang, Lina Zhao and Hongyin Zhang | Jiangsu University, Luoyang Normal University | Bruker timsTOF Pro 2 | timstof-pro-2 | |||
Chromatographic separation of peptides and proteins for characterization of proteomes | Journal article | 2022 | Yu Liang, Lihua Zhang and Yukui Zhang | Chinese Academy of Science | 100 SPD, 200 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 100-spd 200-spd 60-spd | thermo-orbitrap-exploris-480 | |
Insight into the antibacterial mechanism of Cuenriched sol–gel coatings employing proteomics | Journal article | 2022 | Francisco Romero-Gavilán, Iñaki García-Arnáez, Andreia Cerqueira, Loredana Scalschi, Begonya Vicedo, Alejandro Villagrasa, Raúl Izquierdo, Mikel Azkargorta, Félix Elortza, Mariló Gurruchaga, Isabel Goñi and Julio Suay | Universitat Jaume I, Universidad del País Vasco, CIC bioGUNE | Bruker timsTOF Pro | timstof-pro | |||
Proteomic evaluation of human osteoblast responses to titanium implants over time | Journal article | 2022 | Francisco Romero-Gavilán, Andreia Cerqueira, Iñaki García-Arnáez, Mikel Azkargorta, Félix Elortza, Marilo Gurruchaga, Isabel Goñi and Julio Suay | Universitat Jaume I, Universidad del País Vasco, CIC bioGUNE | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
A targeted multiplex mass spectrometry method for quantitation of abundant matrix and cellular proteins in formalin-fixed paraffin embedded arterial tissue | Journal article | 2022 | Anne-Sofie Faarvang Thorsen, Lars Peter Schødt Riber, Lars Melholt Rasmussen and Martin Overgaard | Odense University Hospital. University of Southern Denmark. Steno Diabetes Center Odense. | 60 SPD | Thermo Altis triple quadrupole | 60-spd | thermo-altis-triple-quadrupole | |
Hybrid-DIA: Intelligent Data Acquisition for Simultaneous Targeted and Discovery Phosphoproteomics in Single Spheroids | Journal article | 2022 | Ana Martínez-Val, Kyle Fort, Claire Koenig, Leander Van der Hoeven, Giulia Franciosa, Thomas Moehring , Yasushi Ishihama, Yu-ju Chen, Alexander Makarov, Yue Xuan and Jesper V. Olsen | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen. Thermo Fisher Scientific. Kyoto University. Academia Sinica | Whisper 40 SPD | Thermo Orbitrap Exploris 480 | whisper-40spd | thermo-orbitrap-exploris-480 | |
MS-DAP Platform for Downstream Data Analysis of Label-Free Proteomics Uncovers Optimal Workflows in Benchmark Data Sets and Increased Sensitivity in Analysis of Alzheimer’s Biomarker Data | Publication | 2022 | Frank Koopmans, Ka Wan Li, Remco V. Klaassen, and August B. Smit | VU University | 30 SPD | Bruker timsTOF Pro | 30-spd | timstof-pro | |
Ultra-high sensitivity for targeted clinical proteomics using Evosep-MRM | Poster | 2022 | Angela McArdle, Dorte B. Bekker-Jensen, Bharath Kumar Raghuraman, Nicolai Bache | Evosep Biosystems | Whisper | Agilent 6495 Triple Quadrupole | whisper | agilent-6495-triple-quadrupole | |
A complete and automated sample preparation strategy for high-throughput and standardized proteomics, applied to a clinical cohort of patient plasma samples | Poster | 2022 | Dorte B. Bekker-Jensen, Florian Harking, Magnus Huusfeldt, Ole Østergaard, Lasse Falkenby, Line Vinderslev Iversen, Jakob Bunkenborg, Angie McArdle, Ole B. Hørning, Nicolai Bache, Jesper V. Olsen | Evosep Biosystems, University of Copenhagen, Statens Serum Institut, Bispebjerg University Hospital, | 500 SPD, Whisper 40 SPD | Bruker timsTOF Pro | 500-spd whisper-40spd | bruker-timstof-pro | |
Pushing the boundaries for robust and high-throughput single cell analysis with Whisper Flow technology powered by dia-PASEF | Poster | 2022 | Dorte B. Bekker-Jensen, Christoph Krisp, David Hartlmayr, Anjali Seth, Ole B. Hørning, Moritz Heusel, Magnus Huusfeldt, Andreia Almeida, Markus Lubeck, Gary Kruppa, Jarrod Sandow, Nicolai Bache | Evosep Biosystems, Bruker Daltonics GmBH & Co. KG, Cellenion, IonOpticks, Bruker s.r.o, Brno | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease | Publication | 2022 | Yi‑Long Wang, Meng‑Ying Zhu, Zhe‑Feng Yuan, Xiao‑Yan Ren, Xiao‑Tong Guo, Yi Hua, Lu Xu, Cong‑Ying Zhao, Li‑Hua Jiang, Xin Zhang, Guo‑Xia Sheng, Pei‑Fang Jiang, Zheng‑Yan Zhao, Feng Gao | Zhejiang University School of Medicine | Thermo Q Exactive | thermo-q-exactive | |||
A complete, automated Opentrons OT-2 loading protocol for simplified sample loading of Evotip Pure | Application note | 2022 | Evosep | 100 SPD, 500 SPD, Whisper 40 SPD | Bruker timsTOF Pro | 100-spd 500-spd whisper-40spd | bruker-timstof-pro | ||
Rapid and robust PTM peptide mapping for biologics with the Evosep One and the SCIEX ZenoTOF 7600 | Application note | 2022 | Evosep | 100 SPD, 300 SPD, 60 SPD | SCIEX ZenoTOF 7600 | 100-spd 300-spd 60-spd | sciex-zenotof-7600 | ||
Pushing the boundaries for robust and high-throughput single cell analysis | Application note | 2022 | Evosep | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | ||
Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway | Publication | 2022 | Valdemaras Petrosius, Jan Benada, Olaf Nielsen, Erwin Marten Schoof, Claus Storgaard Sørensen | University of Copenhagen, Technical University of Denmark | 30 SPD | Thermo Fisher Ultimate 3000 | 30-spd | thermo-fisher-ultimate-3000 | |
Robust dimethyl-based multiplex-DIA workflow doubles single-cell proteome depth via a reference channel | Publication | 2023 | Marvin Thielert, Corazon Ericka Mae Itang, Constantin Ammar, Florian A Schober, Isabell Bludau, Patricia Skowronek, Maria Wahle, Wen-Feng Zeng, Xie-Xuan Zhou, Andreas-David Brunner, Sabrina Richter, Fabian J Theis, Martin Steger, Matthias Mann | Max Planck Institute of Biochemistry, Boehringer Ingelheim Pharma GmbH & Co, German Research Center for Environmental Health, Technical University of Munich, NEOsphere Biotechnologies GmbH, University of Copenhagen | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage | Publication | 2022 | Irene González-Recio, Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria Mercado-Gómez, Rubén Rodríguez-Agudo, Sofía Lachiondo Ortega, Clàudia Gil-Pitarch, Carmen Fernández-Rodríguez, Donatello Castellana, Maria U. Latasa, Leticia Abeci | CIC bioGUNE, Universidad de Navarra, Marqués de Valdecilla University Hospital, McGill University, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of the Basque Country (UPV/EHU), Silence Therapeutic | Bruker timsTOF Pro | bruker-timstof-pro | |||
Enhancing single-cell proteomics through tailored Data-Independent Acquisition and micropillar array-based chromatography | Publication | 2022 | Valdemaras Petrosius, Pedro Aragon-Fernandez, Nil Üresin, Teeradon Phlairaharn, Benjamin Furtwängler, Jeff op de Beeck, Simon Francis Thomsen, Ulrich auf dem Keller, Bo T. Porse, Erwin M. Schoof | Technical University of Denmark, University of Copenhagen | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth | Publication | 2022 | Zilu Ye, Gülcan Kilic, Sally Dabelsteen, Irina N. Marinova, Jens F. B. Thøfner, Ming Song, Asha M. Rudjord-Levann, Ieva Bagdonaite, Sergey Y. Vakhrushev, Cord H. Brakebusch, Jesper V. Olsen, Hans H. Wandall | University of Copenhagen | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Two Subgroups within the GH43_36 α-l-Arabinofuranosidase Subfamily Hydrolyze Arabinosyl from Either Mono-or Disubstituted Xylosyl Units in Wheat Arabinoxylan | Publication | 2022 | Kai P. Leschonski, Svend G. Kaasgaard,Nikolaj Spodsberg, Kristian B. R. M. Krogh, Mirjam A. Kabel | Novozymes A/S, Wageningen University | Bruker timsTOF Pro | bruker-timstof-pro | |||
Plasma proteomic profling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways | Publication | 2022 | Madeleine Johansson, HongYan, Charlotte Welinder, ÁkosVégvári, Viktor Hamrefors, Magnus Bäck, Richard Sutton, Artur Fedorowski | Skåne University Hospital, Swedish National Infrastructure for Biological Mass Spectrometry, Karolinska Institutet, Lund University, | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Programmed death ligand 1 intracellular interactions with STAT3 and focal adhesion protein Paxillin facilitate lymphatic endothelial cell remodeling | Publication | 2022 | Johnathon B. Schafer, Erin D. Lucas, PhD, Monika Dzieciettkowska, Tadg Forward, Beth A. Jirón Tamburini | University of Colorado School of Medicine, | Bruker timsTOF Pro | bruker-timstof-pro | |||
Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis | Publication | 2022 | I. García-Arnáeza, F. Romero-Gavilán, A. Cerqueira, F. Elortza, M. Azkargorta, F. Muñoz, M. Mata, J.J. Martín de Llano, J. Suay, M. Gurruchaga, I.Goñia | University of the Basque Country, Universitat Jaume, Basque Research and Technology Alliance, Campus Universitario, iBoneLab SL, University of Valencia, Research Institute of the University Clinical Hospital of Valencia | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Slice-PASEF: fragmenting all ions for maximum sensitivity in proteomics | Publication | 2022 | Lukasz Szyrwiel, Ludwig Sinn, Markus Ralser, Vadim Demichev | Universitätsmedizin Berlin, University of Oxford | 200 SPD | Bruker timsTOF Pro | 200-spd | bruker-timstof-pro | |
Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition | Publication | 2022 | Patricia Skowronek, Florian Krohs, Markus Lubeck, Georg Wallmann, Ericka Itang, Polina Koval, Maria Wahle, Marvin Thielert, Florian Meier, Sander Willems, Oliver Raether, Matthias Mann | Max Planck Institute of Biochemistry, Bruker Daltonics GmbH & Co. KG Bremen, Kyiv Academic University, Jena University Hospital, Bruker Belgium, NNF Center for Protein Research, | 100 SPD, 60 SPD | Bruker timsTOF Pro | 100-spd 60-spd | bruker-timstof-pro | |
Enhanced drug delivery by a prodrug approach effectively relieves neuroinflammation in mice | Publication | 2022 | Ahmed Montaser, Janita Kuiri, Teemu Natunen, Pavel Hruska, David Potesil, Seppo Auriola, Mikko Hiltunen, Tetsuya Terasaki, Marko Lehtonen, Aaro Jalkanen, Kristiina M Huttunen | University of Eastern Finland, Masaryk University, Tohoku University, | |||||
Kinase Inhibitor Pulldown Assay (KiP) for Clinical Proteomics | Publication | 2022 | Alexander B Saltzman, Doug W Chan, Matthew V Holt, Junkai Wang, Eric J Jaehnig, Meenakshi Anurag, Purba Singh, Anna Malovannaya, Beom-Jun Kim, Matthew J Ellis | Baylor College of Medicine, MD Anderson Cancer Center, AstraZeneca, | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
On the potential of micro-flow LC-MS/MS in proteomics | Publication | 2022 | Yangyang Bian, Chunli Gao, Bernhard Kuster, | Northwest University, Technical University of Munich | 300 SPD | AB Sciex TripleTOF 6600 | 300-spd | ab-sciex-tripletof-6600 | |
Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse | Publication | 2022 | Melina Overhoff, Frederik Tellkamp, Simon Hess, Marianna Tolve, Janine Tutas, Marcel Faerfers, Lotte Ickert, Milad Mohammadi, Elodie De Bruyckere, Emmanouela Kallergi, Andrea Delle Vedove, Vassiliki Nikoletopoulou, Brunhilde Wirth, Joerg Isensee, Tim Huch | University of Cologne, University of Lausanne, Leibniz Institute for Molecular Pharmacology, German Center for Neurodegenerative Diseases | Whisper 20 SPD | Thermo Q Exactive 480 | whisper-20spd | thermo-q-exactive-480 | |
A Parallelization Strategy for the Time Efficient Analysis of Thousands of LC/MS Runs in High-Performance Computing Environment | Publication | 2022 | Patrick van Zalm, Arthur Viodé, Kinga Smolen, Benoit Fatou, Arash Nemati Hayati, Christoph N. Schlaffner, Ofer Levy, Judith Steen, Hanno Steen | Boston Children's Hospital | Bruker timsTOF Pro | bruker-timstof-pro | |||
2-O-Methylation of the second transcribed nucleotide within the mRNA 5 cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion | Journal article | 2022 | Karolina Drazkowska, Rafal Tomecki, Marcin Warminski, Natalia Baran, Dominik Cysewski, Anaıs Depaix, Renata Kasprzyk, Joanna Kowalska, Jacek Jemielity, Pawel J. Sikorski | University of Warsaw, Polish Academy of Sciences, Medical University of Bialystok | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Common variable immunodeficiency in two kindreds with heterogeneous phenotypes caused by novel heterozygous NFKB1 mutations | Publication | 2022 | Frederik Staels, Kerstin De Keukeleere, Matias Kinnunen, Salla Keskitalo, Flaminia Lorenzetti, Michiel Vanmeert, Teresa Prezzemolo, Emanuela Pasciuto, Eveline Lescrinier, Xavier Bossuyt, Margaux Gerbaux, Mathijs Willemsen, Julika Neumann, Sien Van Loo, An | KU Leuven, University of Helsinki, University Hospitals Leuven, Babraham Institute | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies Inactivation for Proteomics and Structural Studies | Publication | 2022 | Zlatka Plavec, Aušra Domanska, Xiaonan Liu, Pia Laine, Lars Paulin, Markku Varjosalo, Petri Auvinen, Sharon G. Wolf, Maria Anastasina, Sarah J. Butcher | Molecular and Integrative Biosciences Research Programme, University of Helsinki, Weizmann Institute pf Science, | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Optimizing data points per protein increases protein identifications while maintaining quantitative precision in short gradient data-independent acquisition proteomics | Publication | 2022 | Joerg Doellinger, Christian Blumenscheit, Andy Schneider, Peter Lasch | Robert Koch-Institute | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074, and THR1075) within the COR GTPase domain | Publication | 2022 | Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Sebastian Mathea, Prosenjit Pal, Pawel Lis, Matthew Taylor, Elena Purlyte, Robert Gourlay, Mark Dorward, Simone Weidlich, Rachel Toth, Nicole K. Polinski, Stefan Knapp, Francesca Tonelli & Dario R Al | University of Dundee, Collaborative Research Network, Johann Wolfgang Goethe University, AB Sciex | 30 SPD | Thermo Orbitrap Exploris 240 | 30-spd | thermo-orbitrap-exploris-240 | |
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration | Publication | 2022 | Hyunggu Hahn, Carole Daly, John Little IV, Nicole A. Perry Hauser, Asuka Inoue, Bianca Plouffe, Alex R. B. Thomsen | New York University College of Dentistry, Queen’s University Belfast, Columbia University Vagelos College of Physicians and Surgeons, Tohoku University | Thermo Q Exactive HF-X | thermo-q-exactive-hf-x | |||
Rapid profiling of protein complex re-organization in perturbed systems | Publication | 2022 | Isabell Blau, Charlotte Nicod, Claudia Martelli, Peng Xue, Moritz Heusel Andreas Fossati, Federico Uliana, Fabian Frommelt, Ruedi Aabersold, Ben C. Collins | ETH Zürich, Max Planck Institute of Biochemistry, Lund University, University of California San Francisco, J. David Gladstone Institutes, Queen's University of Belfast | 60 SPD | AB Sciex TripleTOF 6600 | 60-spd | ab-sciex-tripletof-6600 | |
Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines | Publication | 2022 | Sydney Sunna, Christine Bowen, Hollis Zeng, Struti Rayaprolu, Prateek Kumar, Pritha Bagchi, Duc M. Duong, Sara Bitarafan, Aditya Natu, Levi Wood, Nicholas T. Seyfried, Srikant Rangaraju | Emory University, Georgia Institute of Technology | 30 SPD | Thermo Q Exactive | 30-spd | thermo-q-exactive | |
Structural studies reveal that endosomal cations promote formation of 2 infectious CVA9 A particles, facilitating RNA and VP4 release. | Publication | 2022 | Aušra Domanska, Zlatka Plavec, Visa Ruokolainen, Benita Löflund, Varpu Marjomäki, Sarah J Butcher | Faculty of Biological and Environmental Sciences, Molecular and Integrative Bioscience Research Programme, and Helsinki Institute of Life Sciences-Institute of Biotechnology, University of Helsinki, Helsinki, Finland | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Extended detection of anabolics misuse in high-throughput doping controls with the Evosep One | Application note | 2022 | Evosep | 100 SPD | 100-spd | ||||
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes | Publication | 2022 | Maria Mercado-Gómez, Endika Prieto-Fernández, Naroa Goikoetxea-Usandizaga, Laura Vila-Vecilla, Mikel Azkargorta. Miren Bravo, Marina Serrano-Maciá, Leire Egia-Mendikute, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, So Young Lee, Alvaro Eguileor Giné | CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, IIS Hospital La Fe, University of Valencia, Basque Foundation for Science, University of the Basque Country, Centro de Investigación Biomédica En Red de Enferme | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Biomarkers in Neurodegenerative Diseases: Proteomics Spotlight on ALS and Parkinson’s Disease | Publication | 2022 | Rekha Raghunathan, Kathleen Turajane and Li Chin Wong | International Journal of Molecular Sciences | |||||
Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC. | Publication | 2022 | Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte and Philip Cohen | University of Dundee | Thermo Orbitrap Exploris 240 | thermo-orbitrap-exploris-240 | |||
Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells | Publication | 2022 | Camille Ternet, Philipp Junk, Thomas Sevrin, Simona Catozzi, Giorgio Oliviero, Kieran Wynne and Christina Kiel | University College Dublin, University of Pavia | Bruker timsTOF Pro | bruker-timstof-pro | |||
The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies | Publication | 2022 | Steve Sweet, David Chain, WenYu, Philip Martin, Marlon Rebelatto, Andrew Chambers, Fabiola Cecchi and Yeoun Jin Kim | AstraZeneca | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response | Publication | 2022 | Yuxin Mi, Katie L Burnham, Philip D Charles, Raphael Heilig, Iolanda Vendrell, Justin Whalley, Hew D Torrance, David B Antcliffe, Shaun M May, Matt J Neville, Georgina Berridge. Paula Hutton, Cyndi Goh, Jayachandran Radhakrishnan, Alexey Nesvizhskii, | University of Oxford, Wellcome Genome Campus, Imperial College London, Queen Mary University of London, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, University of Michigan, Imperial College Healthcare NHS Trust | 100 SPD | Bruker timsTOF Pro | 100-spd | bruker-timstof-pro | |
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6 | Publication | 2022 | Matthew E. Cockman, Yoichiro Sugimoto, Hamish B. Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R. Flynn, Joanna M. Kirkpatrick, Christopher J. Schofield and Peter J. Ratcliffe | Francis Crick Institute | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
High throughput and high confidence sequence variant analysis in therapeutic antibodies using Evosep One liquid chromatography tandem mass spectrometry with synthetic heavy peptides | Publication | 2022 | Tyler Greer, Reid O'Brien Johnson, Song Nie, Milos Cejkov, Xiaojing Zheng & Ning Li | Regeneron Pharmaceuticals Inc | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms | Publication | 2022 | Marina Garcia-Moreno, Paul M. Jordan, Kerstin Günther, Therese Dau, Christian Fritzsch, Monika Vermes, Astrid Schoppa, Anita Ignatius, Britt Wildemann, Oliver Werz, Bettina Löffler & Lorena Tuchscherr | Jena University Hospital, Friedrich Schiller University Jena, Leibniz Institute on Aging & University Medical Center Ulm | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients | Publication | 2022 | Marina Serrano-Maciá, Sofia Lachiondo-Ortega, Paula Iruzubieta, Naroa Goikoetxea-Usandizaga, Alexandre Bosch, Leire Egia-Mendikute, Borja Jiménez-Lasheras, Mikel Azkargorta, Félix Elortza, Diana Martinez-Redondo, Begoña Castro, Juan J. Lozano, Ruben Nogue | CIC bioGUNE-BRTA, IDIVAL, CIC bioGUNE, CIBEREHD, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Centro de Investigación Biomédica en Red, GAIN, Universidad de Cantabria, Ikerbasque & Basque Foundation for Science | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles | Publication | 2022 | Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Elke Kurz, Audun Kvalvaag, Lina Chen, Charity Ganskow, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Errin Johnson, Jesús A. Siller-Farfán, Omer D | The University of Oxford, Autónoma de Madrid, Centro Nacional de Investigaciones Cardiovasculares (CNIC), University of Oxford, Karolinska Institutet | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
High-throughput quantitative proteomics using Zeno SWATH data-independent analysis (DIA) and the Evosep One system | Application note | 2022 | Ihor Batruch, Yves Le Blanc and Christie Hunter | SCIEX | 100 SPD, 200 SPD, 30 SPD, 60 SPD | SCIEX ZenoTOF 7600 | 100-spd 200-spd 30-spd 60-spd | sciex-zenotof-7600 | |
Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF | Publication | 2022 | Patricia Skowronek, Marvin Thielert, Eugenia Voytik, Maria C. Tanzer, Fynn M. Hansen, Sander Willems, Özge Karayel, Andreas-David Brunner, Florian Meier, Matthias Mann | Max Planck Institute of Biochemistry, Jena University Hospital, University of Copenhagen | 100 SPD, 30 SPD, 60 SPD | Bruker timsTOF Pro | 100-spd 30-spd 60-spd | bruker-timstof-pro | |
Application of In-Cell Fast Photochemical Oxidation of Proteins for the Study of Organoids | Application note | 2022 | Raquel Shortt, Lisa M. Jones | University of Maryland, University of California | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
Brain proteome profling implicates the complement and coagulation cascade in multiple system atrophy brain pathology | Publication | 2022 | Rasmus Rydbirk, Ole Østergaard, Jonas Folke, Casper Hempel, Brian DellaValle, Thomas L. Andresen, Annemette Løkkegaard, Anne‑Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik H. Danielsen, Lisette Salvesen, Charlotte C. Starhof, Sara Bech | Copenhagen University Hospital, University of Copenhagen, Technical University of Denmark, GLX Analytix ApS, Odense University Hospital, Aarhus University Hospital | 30 SPD | Thermo Q Exactive HF-X | 30-spd | thermo-q-exactive-hf-x | |
Noninvasive proteomic biomarkers for alcohol-related liver disease | Publication | 2022 | Lili Niu , Maja Thiele , Philipp E. Geyer, Ditlev Nytoft Rasmussen, Henry Emanuel Webel, Alberto Santos, Rajat Gupta, Florian Meier , Maximilian Strauss , Maria Kjaergaard , Katrine Lindvig, Suganya Jacobsen, Simon Rasmussen , Torben Hansen , Aleksander K | University of Copenhagen, Max Planck Institute of Biochemistry, Odense University Hospital, University of Southern Denmark, Jena University Hospital, University of Oxford, Pfizer Worldwide Research and Development | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Advances in data‐independent acquisition massspectrometry towards comprehensive digital proteomelandscape | Publication | 2022 | Reta Birhanu Kitata, Jhih‐Ci Yang, Yu‐Ju Chen | Academia Sinica, National Yang Ming Chiao Tung University, National Taiwan University | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Engineered SH2 Domains for Targeted Phosphoproteomics | Publication | 2022 | Gregory D. Martyn, Gianluca Veggiani, Ulrike Kusebauch, Seamus R. Morrone, Bradley P. Yates, Alex U. Singer, Jiefei Tong, Noah Manczyk, Gerald Gish, Zhi Sun, Igor Kurinov, Frank Sicheri, Michael F. Moran, Robert L. Moritz and Sachdev S. Sidhu | University of Toronto, Institute for Systems Biology Washington, Hospital for Sick Children Toronto, Mount Sinai Hospital, Cornell University | |||||
Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes | Publication | 2022 | Mirolyuba Ilieva, Blanca Irene Aldana, Kasper Tore Vinten, Sonja Hohmann, Thomas William Woofenden, Renate Lukjanska, Helle S Waagepetersen, Tanja Maria Michel | University of Southern Denmark, Odense University Hospital, Aalborg University, University of Copenhagen | 30 SPD | Thermo Orbitrap Fusion | 30-spd | thermo-orbitrap-fusion | |
Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction | Publication | 2022 | Mehari Muuz Weldemariam, Jongmin Woo & Qibin Zhang | University of North Carolina at Greensboro | |||||
Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications | Publication | 2022 | Loïc Dayon, Ornella Cominetti & Michael Affolter | Proteomics, Bioanalytics Department, Nestlé Institute of Food Safety & Analytical Sciences, Institut des Sciences et Ingénierie Chimiques | |||||
Evaluation of the Suitability of Dried Saliva Spots for In-Depth Proteome Analyses for Clinical Applications | Publication | 2022 | Hironori Sato, Daisuke Nakajima, Masaki Ishikawa, Ryo Konno, Ren Nakamura, Osamu Ohara, & Yusuke Kawashima | Department of Applied Genomics, Kazusa DNA Research Institute, Department of Pediatrics, Graduate School of Medicine, Chiba University | |||||
Inflammation-induced downregulation of succinate dehydrogenase regulates adrenocortical function | Publication | 2022 | Ivona Mateska, Anke Witt, Eman Hagag, Anupam Sinha, Canelif Yilmaz, Evangelia Thanou, Na Sun, Ourania Kolliniati, Maria Patschin, Heba Abdelmegeed, Holger Henneicke, Waldemar Kanczkowski, Ben Wielockx, Christos Tsatsanis, Andreas Dahl, Axel Walch, Ka Wan | Technische Universität Dresden, Germany, Vrije Universiteit, Netherlands, Helmholtz Centrum München, Germany, University of Crete, Greece | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Zwitter-ionic monolith-based spintip column coupled with Evosep One liquid chromatography for high-throughput proteomic analysis | Publication | 2022 | Yiran Su, Xi Wang, Yun Yang, Lijun Yang, Ruilian Xu, Ruijun Tian | Southern Univrsity of Science and Technology, China, Jinan University, China, | Whisper 20 SPD | Bruker timsTOF Pro | whisper-20spd | bruker-timstof-pro | |
Ultra sensitive and high throughput proteomics on the standardized Evosep One platform | Webinar | 2021 | Jesper Olsen, Erwin M. Schoof | University of Copenhagen, Technical University of Denmark | Whisper 20 SPD, Whisper 40 SPD | Thermo Orbitrap Exploris 480 | whisper-20spd whisper-40spd | thermo-orbitrap-exploris-480 | |
A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens | Publication | 2022 | Georgia Mitsa, Qianyu Guo, Christophe Goncalves, Samuel E J Preston, Vincent Lacasse, Adriana Aguilar-Mahecha, Naciba Benlimame, Mark Basik, Alan Spatz, Gerald Batist, Wilson H Miller Jr, Sonia V Del Rincon, René P Zahedi, Christoph H Borchers | International Journal of Molecular Sciences | |||||
Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes | Publication | 2022 | Shideh Mirhadi, Shirley Tam, Quan Li, Nadeem Moghal, Nhu-An Pham, Jiefei Tong, Brian J. Golbourn, Jonathan R. Krieger, Paul Taylor, Ming Li, Jessica Weiss, Sebastiao N. Martins-Filho ,Vibha Raghavan, Yasin Mamatjan, Aafaque A. Khan, Michael Cabanero, Shin | Nature Communications | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
DebaryOmics: an integrative –omics study to understand the halophilic behaviour of Debaryomyces hansenii | Publication | 2022 | Clara Navarrete, Benjamín J. Sánchez, Simonas Savickas, José Luis Martínez Ruiz | Department of Biotechnology and Biomedicine,Technical University of Denmark | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes | Publication | 2022 | Anna Maria Sole Giordano, Marco Luciani, Francesca Gatto, Monah Abou Alezz, Chiara Beghè, Lucrezia Della Volpe, Alessandro Migliara, Sara Valsoni, Marco Genua, Monika Dzieciatkowska, Giacomo Frati, Julie Tahraoui-Bories, Silvia Clara Giliani, Simona Orces | Journal of Experimental Medicine | Bruker timsTOF Pro | bruker-timstof-pro | |||
Chemical probing provides insight into the native assembly state of a bacterial microcompartment | Publication | 2022 | Daniel S. Trettel, William Resager, Beatrix M. Ueberheide, Conor C. Jenkins, Wade C.Winkler | University of Maryland, New York University Grossman School of Health, New York University Grossman School of Medicine | |||||
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons | Publication | 2022 | Chun-I Wu, Elizabeth A. Vinton, Richard V. Pearse II, Keunjung Heo, Aimee J. Aylward, Yi-Chen Hsieh, Yan Bi, Sopefoluwa Adeleye, Seeley Fancher, Duc M. Duong, Nicholas T. Seyfried, Thomas L. Schwarz & Tracy L. Young-Pearse | Molecular Psychiatry | |||||
Nano-LC: An updated review | Publication | 2022 | Lian Shan, Barry R Jones | LC-MS Biologics, QSquared Solutions | |||||
Development of Fast Photochemical Oxidation of Proteins for in Vivo Modification in Caenorhabditis elegans | Case study | 2022 | Jessica Arlett Espino | University of Maryland | Thermo Orbitrap Fusion Lumos, Thermo Q Exactive HF | thermo-orbitrap-fusion-lumos thermo-q-exactive-hf | |||
Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics | Publication | 2021 | Roger Moreno-Justicia, Alba Gonzalez-Franquesa, Ben Stocks, Atul S. Deshmukh | Novo Nordisk Foundation (NNF), Copenhagen Denmark | Thermo Q Exactive HF-X | thermo-q-exactive-hf-x | |||
Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity | Publication | 2022 | Jaione Auzmendi-Iriarte, Maddalen Otaegi-Ugartemendia, Estefania Carrasco-Garcia, Mikel Azkargorta, Antonio Diaz, Ander Saenz-Antonanzas, Joaquin Andrés Andermatten, Mikel Garcia-Puga, Idoia Garcia | University of the Basque Country | Bruker timsTOF Pro | bruker-timstof-pro | |||
Robust and high-throughput single cell proteomics with the Evosep One | Application note | 2022 | Evosep | Whisper 40 SPD | whisper-40spd | ||||
Comprehensive proteomics with 8.000 proteins identified with DIA-PASEF using the 30 samples per day method | Application note | 2022 | Evosep | 30 SPD | 30-spd | ||||
A semi automated AssayMAP bravo protocol for robust Evotip loading and high-throughput analysis on the Evosep One | Application note | 2022 | Evosep | ||||||
Improve and enhance your proteome coverage with the performance column for our long methods | Application note | 2022 | Evosep | 30 SPD, Extended method | Bruker timsTOF Pro | 30-spd extended-method | bruker-timstof-pro | ||
ASMS 2022 highlights: Robust and high-throughput analysis with ultra-high sensitivity | Webinar | 2022 | Dorte Bekker-Jensen, Angela Mc Ardle, Nicolai Bache | Evosep | |||||
High sensitivity limited material proteomics empowered by data- independent acquisition on linear ion traps | Publication | 2022 | Teeradon Phlairaharn, Lukas R. Woltereck, Samuel Grégoire, Benjamin Furtwängler, Erwin M. Schoof | Technical University of Denmark | Whisper 20 SPD, Whisper 40 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd whisper-40spd | thermo-orbitrap-eclipse-tribid | |
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation | Publication | 2022 | Kim Theilgaard-Mönch, Sachin Pundhir, Kristian Reckzeh, Jinyu Su, Marta Tapia, Benjamin Furtwängler, Johan Jendholm, Janus Schou Jakobsen, Marie Sigurd Hasemann, Kasper Jermiin Knudsen, Jack Bernard Cowland, Anna Fossum, Erwin Schoof | University of Copenhagen, Technical University of Denmark | Whisper 20 SPD | Thermo Orbitrap Eclipse Tribid | whisper-20spd | thermo-orbitrap-eclipse-tribid | |
Using Targeted Liquid Chromatography-Tandem Mass Spectrometry to Rapidly Detect β-Lactam, Aminoglycoside, and Fluoroquinolone Resistance Mechanisms in Blood Cultures Growing E. coli or K. pneumoniae | Publication | 2022 | Dimard E. Foudraine, Lennard J. M. Dekker, Nikolaos Strepis, Stan J. Nispeling, Merel N. Raaphorst, Wendy Kloezen, Piet Colle, Annelies Verbon, Corné H. W. Klaassen, Theo M. Luider, Wil H. F. Goessens | Erasmus MC | 100 SPD | Thermo Orbitrap Fusion, Thermo Q Exactive | 100-spd | thermo-orbitrap-fusion thermo-q-exactive | |
Profiling the Plasma Apolipoproteome of Normo- and Hyperlipidemic Mice by Targeted Mass Spectrometry | Publication | 2022 | Lasse Bach Steffensen, Jannik Larsen, Didde Riisager Hansen, Thi My Linh Tha, Niels Strømvig Larsen, Hans Christian Beck, Lars Melholt Rasmussen, Martin Overgaard | University of Southern Denmark (SDU), Odense | |||||
Antimicrobial resistance with the Evosep One | Webinar | 2022 | Dimard Foudraine, Florence Roux Dalvai | Erasmus MC, Laval University | |||||
Toxoplasma gondii ROP1 subverts murine and human innate immune restriction | Publication | 2022 | Simon Butterworth, Francesca Torelli, Eloise J. Lockyer, Jeanette Wagener, Ok-Ryul Song, Malgorzata Broncel, Matt R. G. Russell, Joanna C. Young, Moritz Treeck | The Francis Crick Institute, London. | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
A fast and sensitive absolute quantification assay for the detection of sars-cov-2 peptides using parallel reaction monitoring mass spectrometry | Publication | 2022 | Akshada Gajbhiye, Atakan Nalbant, Tiaan Heunis, Frances Sidgwick, Andrew Porter, Yusri Taha, Matthias Trost | Newcastle University | 200 SPD | Thermo Q Exactive HF | 200-spd | thermo-q-exactive-hf | |
ABPP-HT* – Deep meets fast for activity-based profiling of deubiquitylating enzymes using advanced DIA and DDA mass spectrometry methods | Publication | 2022 | Hannah B. L. Jones, Raphael Heilig, Simon Davis, Roman Fischer, Benedikt M. Kessler, Adán Pinto-Fernandez | University of Oxford | 100 SPD | Bruker timsTOF Pro | 100-spd | bruker-timstof-pro | |
Numb exon 9 inclusion regulates Integrinβ5 surface expression and promotes breast cancer metastasis | Publication | 2022 | Yangjing Zhang, Sascha E. Dho, Kamal Othman, Craig D. Simpson, Jessica Lapierre, Andrew Bondoc & C. Jane McGlade | Department of Medical Biophysics, University of Toronto., The Arthur and Sonia Labatt Brain Tumour Research Centre., SPARC BioCentre, The Hospital for Sick Children. | |||||
Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion | Publication | 2022 | Vassilis L. Tzounakas, Alkmini T. Anastasiadi, Davide Stefanoni, Francesca Cendali, Lorenzo Bertolone, Fabia Gamboni, Monika Dzieciatkowska, Pantelis Rousakis, Athina Vergaki, Vassilis Soulakis, Ourania E. Tsitsilonis, Konstantinos Stamoulis, Issidora S. | Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens., Department of Biochemistry and Molecular Genetics, University of Colorado, School of Medicine-Anschutz Medical Campus. | Bruker timsTOF Pro | bruker-timstof-pro | |||
High-Field Asymmetric Waveform Ion Mobility Spectrometry and Parallel Reaction Monitoring Increases Sensitivity for Clinical Biomarker Quantitation from FormalinFixed, Paraffin-Embedded Tumor Biopsies | Publication | 2022 | Steve Sweet, David Chain, Wen Yu, Philip Martin, Marlon Rebelatto, Andrew Chambers,1 Fabiola Cecchi, Yeoun Jin Kim | Translational Medicine, Oncology R&D, Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
The setup and optimization of a complete global proteomics two-dimensional liquid chromatography system, using Spider Fractionation | Publication | 2021 | Eris Aas Bakketeig | University of Oslo, Oslo, Norway | Extended method | Thermo Q Exactive HF | extended-method | thermo-q-exactive-hf | |
Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion | Publication | 2022 | Leonie van Leeuwen, Leonie H. Venema, Raphael Heilig, Henri G. D. Leuvenink, Benedikt M. Kessler | University of Groningen, Groningen, The Netherlands, Target Discovery Institute, University of Oxford, Oxford, UK, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK | Bruker timsTOF Pro | bruker-timstof-pro | |||
P018 Proteomic profile of serum and urine in newly diagnosed patients with Inflammatory Bowel Disease: new approach for biomarker discovery | Publication | 2022 | Montse Baldan Martin, Mikel Azkargorta Mujika, Lorena Ortega-Moreno | Hospital Universitario de La Princesa, CIC bioGune, Bilbao, Spain | Bruker timsTOF Pro | bruker-timstof-pro | |||
Recent Developments in Clinical Plasma Proteomics—Applied to Cardiovascular Research | Publication | 2022 | Nicolai Bjødstrup Palstrøm, Rune Matthiesen, Lars Melholt Rasmussen, Hans Christian Beck | Odense University Hospital, Odense, Denmark, Universidade NOVA de Lisboa, Lisbon, Portugal | |||||
Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis | Publication | 2022 | Hanne Van Der Heijden, Benoit Fatou, Kacie Hoyt, Benjamin Goodlett, Camilo Jaimes, Hanno Steen, Jaymin Upadhyay | Boston Children’s Hospital MA, USA, Maastricht University, Maastricht, The Netherlands, University of Amsterdam, Amsterdam, The Netherlands, BioSAS Consulting, Inc, Wellesley, MA, USA, McLean Hospital, Harvard Medical School, MA, Belmont, USA | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase | Publication | 2021 | Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro Costa | The Francis Crick Institute, London, UK | 30 SPD | Thermo Orbitrap Lumos | 30-spd | thermo-orbitrap-lumos | |
FASN-dependent de novo lipogenesis is required for brain development | Publication | 2022 | Daniel Gonzalez-Bohorquez, Isabel M. Gallego López, Baptiste N. Jaeger, Sibylle Pfammatter, Megan Bowers, Clay F. Semenkovich & Sebastian Jessberger | University of Zurich, Switzerland. University School of Medicine, St. Louis, US | Extended method | Bruker timsTOF Pro | extended-method | bruker-timstof-pro | |
Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19 | Publication | 2022 | Srikanth Mairpady Shambat, Alejandro Gómez-Mejia, Tiziano A. Schweizer, Markus Huemer, Chun-Chi Chang, Claudio Acevedo, Judith Bergada-Pijuan, Clément Vulin, Daniel A. Hofmaenner, Thomas C. Scheier, Sanne Hertegonne, Elena Parietti, Nataliya Miroshnikova, | University Hospital of Zurich, University of Zurich, Switzerland | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
Introducing Evotip Pure: A new generation of Evotip – It’s all in the tip | Webinar | 2022 | Nicolai Bache, Dorte Bekker-Jensen | Evosep | |||||
Ultra-high sensitivity proteomics on the timsTOF SCP | Application note | 2021 | Nagarjuna Nagaraj, Thomas Kosinski, Amalia Apalategui Pierre-Olivier Schmit, Markus Lubeck, Oliver Raether & Gary Kruppa | Bruker, Germany. | Whisper 40 SPD | Bruker timsTOF SCP | whisper-40spd | bruker-timstof-scp | |
The social architecture of an in-depth cellular protein interactome | Publication | 2021 | André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau & Matthias Mann | Max-Planck Institute of Biochemistry, Martinsried, Germany | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
Data independent acquisition enables deep and fast label-free dynamic organellar mapping | Publication | 2021 | Julia P. Schessner, Vincent Albrecht, Alexandra K. Davies, Pavel Sinitcyn & Georg H.H. Borner | Max-Planck Institute of Biochemistry, Martinsried, Germany | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Fully Automated High-Throughput Host Cell Protein Analysis of Highly Diverse Samples | Application note | 2021 | Anders Giessing | 200 SPD | Bruker timsTOF | 200-spd | bruker-timstof | ||
Evotip Pure: A new generation of Evotip | Brochure | 2022 | Evosep | ||||||
Unleash the power of DIA | Webinar | 2022 | Patricia Skowronek, Yves Le Blanc, Ihor Batruch | Max Planck Institute of Biochemistry, Sciex | |||||
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation | Publication | 2020 | Andreas-David Brunner, Marvin Thielert, Catherine Vasilopoulou, Constantin Ammar, Fabian Coscia, Andreas Mund, Ole B. Horning, Nicolai Bache, Amalia Apalategui, Markus Lubeck, Oliver Raether, Melvin A. Park, Sabrina Richter, David S. Fischer, Fabian J. Th | Max Planck Institute of Biochemistry, Martinsried, Germany. Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark. Evosep Biosystems, Denmark. Bruker Daltonik, Germany and United States. Helmholtz Zentrum München, Germany. | Whisper 40 SPD | Bruker timsTOF Pro, Bruker timsTOF SCP | Download publication or learn more on our website | whisper-40spd | bruker-timstof-pro bruker-timstof-scp |
Proteomics at the single cell level with Evosep Whisper and the timsTOF SCP | Application note | 2022 | Bruker Daltonics | Whisper 40 SPD | Bruker timsTOF Pro | whisper-40spd | bruker-timstof-pro | ||
Evosep One in the clinical biochemistry lab | Webinar | 2022 | Nicolai Jacob Wewer Albrechtsen, Martin Overgaard | Odense University Hospital, University of Southern Denmark, NNF center for protein research, University of Copenhagen | |||||
A beginner’s guide to Evosep | Webinar | 2022 | Nicolai Bache & Ireshyn Govender | Evosep, Resyn Biosciences | |||||
Whisper is here | Webinar | 2021 | Christoph Krisp & Angela Kruse | Bruker, Vanderbilt University | |||||
FFPE Tissue Analysis on the Evosep One | Webinar | 2021 | Bernhard Kuster & Lisa Schweizer | Technical University of Munich, Max Planck Institute of Biochemistry | |||||
Automated sample prep workflows | Webinar | 2021 | Philipp E. Geyer & Dorte Bekker-Jensen | Omicera Diagnostics, Evosep | |||||
Development of a Standardized Microflow LC Gradient to Enable Sensitive and Long-Term Detection of Synthetic Anabolic-Androgenic Steroids for High-Throughput Doping Controls | Publication | 2021 | Vivian Delcourt, Patrice Garcia, Isabelle Pottier, Nasrine Mansoibou, Nicolai Bache, Yohan Glavieux, Benjamin Chabot, Isabelle Perot, Isabelle Perot, François André, Benoit Loup, Agnès Barnabé, Marie-Agnès Popot & Ludovic Bailly-Chouriberry | GIE-LCH, Laboratoire Des Courses Hippiques, France. Evosep. | High Organic Method | Thermo Q Exactive HF | high-organic-method | thermo-q-exactive-hf | |
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk | Publication | 2021 | Beate Vestad, Tuula A. Nyman, Malene Hove‑Skovsgaard, Maria Stensland, Hedda Hoel, Anne‑Marie Siebke Trøseid, Trude Aspelin, Hans Christian D. Aass, Maija Puhka, Johannes R. Hov, Susanne Dam Nielsen, Reidun Øvstebø & Marius Trøseid | Oslo University Hospital Rikshospitalet, Oslo, Norway. University of Oslo, Oslo, Norway. Norwegian Society for Extracellular Vesicles, Oslo, Norway. University Hospital of Copenhagen Rigshospitalet, Copenhagen, Denmark. Lovisenberg Diaconal Hospital, Oslo | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
DebaryOmics: an integrative –omics study to understand the halophilic behaviour of Debaryomyces hansenii | Publication | 2021 | Clara Navarrete, Benjamín J. Sánchez, Simonas Savickas, José L. Martínez | Technical University of Denmark. Denmark. | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Evaluation of Disposable Trap Column nanoLC–FAIMS–MS/MS for the Proteomic Analysis of FFPE Tissue | Publication | 2021 | Stephan Eckert, Yun-Chien Chang, Florian P. Bayer, Matthew The, Peer-Hendrik Kuhn, Wilko Weichert & Bernhard Kuster | Technical University of Munich, Munich, Germany. | 30 SPD, 60 SPD, Extended method | Thermo Orbitrap Exploris 480 | 30-spd 60-spd extended-method | thermo-orbitrap-exploris-480 | |
High-Throughput Drug Discovery with the Evosep One | Webinar | 2021 | Casimir Bamberger & Tanveer S. Batth | Scripps Research Institute & Novo Nordisk Foundation Center for Protein Research | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Targeted Workflows with Evosep One | Webinar | 2021 | Michael Maccoss & Vivian Delcourt | University of Washington & Laboratoire Des Courses Hippiques | High Organic Method | high-organic-method | |||
Plasma Proteomics with the Evosep One | Webinar | 2021 | Roman Fischer & Lili Niu | University of Oxford & Novo Nordisk Foundation Center for Protein Research | 30 SPD | Bruker timsTOF Pro, Thermo Orbitrap Exploris 480 | 30-spd | bruker-timstof-pro thermo-orbitrap-exploris-480 | |
Discovery Proteomics for COVID-19: Where We Are Now | Publication | 2021 | Angela McArdle, Kirstin E. Washington, Blandine Chazarin Orgel, Aleksandra Binek, Danica-Mae Manalo, Alejandro Rivas, Matthew Ayres, Rakhi Pandey, Connor Phebus, Koen Raedschelders, Justyna Fert-Bober & Jennifer E Van Eyk | Cedars-Sinai Medical Center, Los Angeles, California, United States | |||||
AlphaTims: Indexing Trapped Ion Mobility Spectrometry–TOF Data for Fast and Easy Accession and Visualization | Publication | 2021 | Sander Willems, Eugenia Voytik, Patricia Skowronek, Maximilian T. Strauss & Matthias Mann | Max Planck Institute of Biochemistry, Martinsried, Germany. OmicEra Diagnostics GmbH, Planegg, Germany. University of Copenhagen, Copenhagen, Denmark | 200 SPD, 60 SPD | Bruker timsTOF Pro | 200-spd 60-spd | bruker-timstof-pro | |
Deep neural network for detecting arbitrary precision peptide features through attention based segmentation | Publication | 2021 | Fatema Tuz Zohora, M. Ziaur Rahman, Ngoc Hieu Tran, Lei Xin, Baozhen Shan & Ming Li | University of Waterloo, Waterloo, Canada. Bioinformatics Solutions Inc., Waterloo, Canada. | |||||
A deeper look at carrier proteome effects for single-cell proteomics | Publication | 2021 | Zilu Ye, Tanveer Batth, Patrick L. Rüther, Jesper V. Olsen | University of Copenhagen | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
Time evolution of PEG-shedding and serum protein coronation determines the cell uptake kinetics and delivery of lipid nanoparticle formulated mRNA | Publication | 2021 | A. Gallud, M. J. Munson, K. Liu, A. Idström, H. M. G. Barriga, S. R. Tabaei, N. Aliakbarinodehi, M. Ojansivu, Q. Lubart, J. J. Doutch, M. N. Holme, L. Evenäs, L. Lindfors, M. M. Stevens, A. Collén, A. Sabirsh, F. Höök, E. K. Esbjörner. | Chalmers University of Technology, Gothenburg, Sweden. AstraZeneca, Gothenburg, Sweden. Karolinska Institute, Stockholm, Sweden. Rutherford Appleton Laboratory, Didcot, UK. Imperial College London, UK. | 30 SPD | Thermo Q Exactive HF | 30-spd | thermo-q-exactive-hf | |
PD-L1 Overexpression, SWI/SNF Complex Deregulation, and Profound Transcriptomic Changes Characterize Cancer-Dependent Exhaustion of Persistently Activated CD4+ T Cells | Publication | 2021 | Iga Jancewicz, Joanna Szarkowska, Ryszard Konopinski, Malgorzata Stachowiak, Monika Swiatek, Katarzyna Blachnio, Szymon Kubala, Paulina Oksinska, Pawel Cwiek, Natalia Rusetska, Agnieszka Tupalska, Natalia Zeber-Lubecka, Ewa Grabowska, Bianka Swiderska, | Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. Polish Academy of Sciences, 02-106 Warsaw, Poland. University Hospital Basel and University of Basel, 4001 Basel, Switzerland. Centre of Postgraduate Medical Education, 01-8 | 30 SPD | Thermo Orbitrap Exploris 480 | 30-spd | thermo-orbitrap-exploris-480 | |
A universal peptide matrix interactomics approach to disclose motif dependent protein binding | Publication | 2021 | Evelyn Ramberger, Lorena Suarez-Artiles, Daniel Perez-Hernandez, Mohamad Haji, Oliver Popp, Ulf Reimer, Achim Leutz, Gunnar Dittmar & Philipp Mertins | Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. Luxembourg Institute of Health, Luxembourg. JPT Peptide Technologies GmbH, Berlin, Germany. Humboldt University of Berlin, Berlin, Germany. University of Luxembourg | 60 SPD | Thermo Q Exactive HF-X | 60-spd | thermo-q-exactive-hf-x | |
Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study | Publication | 2021 | IMPACC Manuscript Writing Team | IMPACC | Bruker timsTOF Pro | bruker-timstof-pro | |||
AlphaPept, a modern and open framework for MS-based proteomics | Publication | 2021 | Maximilian T. Strauss, Isabell Bludau, Wen-Feng Zeng, Eugenia Voytik, Constantin Ammar, Julia Schessner, Rajesh Ilango, Michelle Gill, Florian Meier, Sander Willems & Matthias Mann | Max Planck Institute of Biochemistry, Martinsried, Germany. University of Copenhagen, Denmark. Nvidia Corporation, Santa Clara, CA, USA. OmicEra Diagnostics GmbH, Planegg, Germany. Jena University Hospital, Jena, Germany. | 200 SPD | Bruker timsTOF Pro | 200-spd | bruker-timstof-pro | |
A personalized mass spectrometry-based assay to monitor M-protein in multiple myeloma patients (EasyM) | Publication | 2021 | Mariya Liyasova, Zac McDonald, Paul Taylor, Kathleen Gorospe, Xin Xu, Chenyu Yao, Qixin Liu, Liqiang Yang, Eshetu G. Atenafu, Giovanni Piza, Bin Ma, Donna Reece, Suzanne Trudel | Rapid Novor, Canada. University of Waterloo, Canada. Princess Margaret Cancer Centre, Canada. | 30 SPD, 60 SPD | Thermo Orbitrap Fusion, Thermo Q Exactive | 30-spd 60-spd | thermo-orbitrap-fusion thermo-q-exactive | |
Exploitation of the Secretory Pathway by SARS-CoV-2 Envelope | Publication | 2021 | Guy J Pearson, Malgorzata Broncel, Ambrosius P Snijders & Jeremy G Carlton | King’s College London, UK. The Francis Crick Institute, UK. | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
Mass Spectrometry Provides a Highly Sensitive Noninvasive Means of Sequencing and Tracking M-Protein in the Blood of Multiple Myeloma Patients | Publication | 2021 | Zac McDonald, Paul Taylor, Mariya Liyasova, Qixin Liu & Bin Ma | Rapid Novor, Canada | 30 SPD | Thermo Q Exactive | 30-spd | thermo-q-exactive | |
Rapid and Accurate Detection of Aminoglycoside-Modifying Enzymes and 16S rRNA Methyltransferases by Targeted Liquid Chromatography-Tandem Mass | Publication | 2021 | Dimard E. Foudrainehttps, Nikolaos Strepisa, Corné H. W. Klaassenhttps, Merel N. Raaphorsta, Annelies Verbona, Theo M. Luiderb, Wil H. F. Goessensa & Lennard J. M. | Erasmus MC University Medical Center, Rotterdam, The Netherlands | 100 SPD | Thermo Q Exactive HF | 100-spd | thermo-q-exactive-hf | |
Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses | Publication | 2021 | Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Audun Kvalvaag, Elke Kurz, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Jesús A. Siller-Farfán, Omer Dushek, Michal Maj, Erdinc Sezgin, Ben Peaco | The University of Oxford, Oxford, UK. Universidad Autónoma de Madrid, Madrid, Spain. Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. Karolinska Institutet, Stockholm, Sweden. MediCity, Nottingham, UK. | 60 SPD | Bruker timsTOF Pro | 60-spd | bruker-timstof-pro | |
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity | Publication | 2021 | COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium, Julian C Knight. | University of Oxford | 100 SPD | Bruker timsTOF Pro | 100-spd | bruker-timstof-pro | |
An ultrasensitive method for analysis of viral spike N-glycoforms | Publication | 2021 | Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson & John R Yates III | Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA. The Scripps Research Institute, La Jolla, CA, USA. | 30 SPD, Extended method | Bruker timsTOF Pro | 30-spd extended-method | bruker-timstof-pro | |
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures | Publication | 2021 | Giulia Franciosa, Jos G. A. Smits, Sonia Minuzzo, Ana Martinez-Val, Stefano Indraccolo & Jesper V. Olsen | University of Padova, Padova, Italy. University of Copenhagen, Denmark. | 30 SPD, 60 SPD | Thermo Orbitrap Exploris 480 | 30-spd 60-spd | thermo-orbitrap-exploris-480 | |
Inhibition of eEF2K synergizes with glutaminase inhibitors or 4EBP1 depletion to suppress growth of triple-negative breast cancer cells | Publication | 2021 | YoungJun Ju, Yaacov Ben-David, Daniela Rotin & Eldad Zacksenhaus | University Health Network, Toronto, Canada. Chinese Academic of Sciences, Guiyang, China. Guizhou Medical University, Guiyang, China. The Hospital for Sick Children, Toronto, Canada. | Thermo Orbitrap Fusion Lumos | thermo-orbitrap-fusion-lumos | |||
A fleet of Evosep One instruments supports a proteomics factory at Rapid Novor | Case study | 2021 | Evosep. Rapid Novor | Evosep. Rapid Novor | |||||
High Sensitivity Evotips | Brochure | 2021 | Evosep | Evosep | |||||
Unleashing the power of DIA combined with short gradients using Evosep One | Webinar | 2021 | Florian Meier & Vadim Demchev | Friedrich Shiller University, Jena, Germany. Francis Crick Institute, UK. | 100 SPD, 200 SPD, 60 SPD | Bruker timsTOF Pro | 100-spd 200-spd 60-spd | bruker-timstof-pro | |
Unleashing the true power of DIA/SWATH data acquisition with short gradients – Rapid profiling of pre-clinical models and proteome dynamics | Application note | 2019 | Evosep | ||||||
Improve and enhance your proteome coverage with the Performance column | Application note | 2019 | Evosep | 100 SPD, 60 SPD | 100-spd 60-spd | ||||
Evosep One: A Separation Tool Designed for Clinical Omics | Brochure | 2019 | Evosep | ||||||
Co-translational assembly and localized translation of nucleoporins in nuclear pore complex biogenesis | Publication | 2021 | Ophélie Lautier, Arianna Penzo, Jérôme Rouvière, Guillaume Chevreux, Louis Collet, Isabelle Loïodice, Angela Taddei, Frédéric Devaux, Martine A. Collart & Benoit Palancade | Université de Paris, Paris, France. Sorbonne Université, Paris, France. University of Geneva, Geneva, Switzerland. | 30 SPD | 30-spd | |||
Hemorrhage and saline resuscitation are associated with epigenetic and proteomic reprogramming in the rat lung | Publication | 2021 | Alexander Bonde, Trine G. Eskesen, Jacob Steinmetz, Erwin M. Schoof, Lene H.D. Blicher, Lars S. Rasmussen & Martin Sillesen | Rigshospitalet, University of Copenhagen, Denmark. Technical University of Denmark, Lyngby, Denmark. | 30 SPD | Thermo Orbitrap Fusion | 30-spd | thermo-orbitrap-fusion | |
Standardized workflow for precise mid- and high-throughput proteomics of blood biofluids | Webinar | 2021 | Angela Mc Ardle, Aleksandra Binek, Annie Moradian, Blandine Chazarin Orgel, Alejandro Rivas, Kirstin E. Washington, Conor Phebus, Danica-Mae Manalo, James Go, Vidya Venkatraman, Casey Johnson, Qin Fu, Susan Cheng, Koen Raedschelders, Justyna-Fert Bober, S | Cedars-Sinai Medical Center, Los Angeles, CA, United States. University College Dublin, Dublin, Ireland. | 60 SPD | Thermo Orbitrap Exploris 480 | 60-spd | thermo-orbitrap-exploris-480 | |
Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony | Publication | 2021 | Abigail J. Perrin, Claudine Bisson, Peter A. Faull, Matthew J. Renshaw, Rebecca A. Lees, Roland A. Fleck, Helen R. Saibil, Ambrosius P. Snijders, David A. Baker & Michael J. Blackman | The Francis Crick Institute, London, UK. University of London, London, UK. King’s College London, London, UK. London School of Hygiene & Tropical Medicine, London, UK | 30 SPD | Thermo Orbitrap Fusion Lumos | 30-spd | thermo-orbitrap-fusion-lumos | |
The COVIDome Explorer Researcher Portal | Publication | 2021 | Kelly D. Sullivan, Matthew D. Galbraith, Kohl T. Kinning, Kyle Bartsch, Nik Levinsky, Paula Araya, Keith P. Smith, Ross E. Granrath, Jessica R. Shaw, Ryan Baxter, Kimberly R. Jordan, Seth Russell, Monika Dzieciatkowska, Julie A. Reisz, Fabia Gamboni, Fran | University of Colorado, CO, USA. University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Colorado School of Public Health, Aurora, CO, USA. | 30 SPD | Bruker timsTOF Pro | 30-spd | bruker-timstof-pro | |
High sensitivity dia-PASEF proteomics with DIA-NN and FragPipe | Publication | 2021 | Vadim Demichev, Fengchao Yu, Guo Ci Teo, Lukasz Szyrwiel, George A. Rosenberger, Jens Decker, Stephanie Kaspar-Schoenefeld, Kathryn S. Lilley, Michael Mülleder, Alexey I. Nesvizhskii & Markus Ralser | The Francis Crick Institute, London, UK. Charité – Universitätsmedizin Berlin, Germany. University of Cambridge, UK. University of Michigan, Ann Arbor, USA. Columbia University, New York, USA. Bruker Daltonics, Bremen, Germany | 100 SPD, 200 SPD, 60 SPD | Bruker timsTOF Pro | Download publication or learn more |