Standardized Tools from Sample to Separation

Actionable insights at scale

LC-MS based proteomics offer powerful biological insights, but workflows are too often expert-dependent and variable. Manual steps and inconsistent execution create complexity – limiting scalability and undermining data confidence.

Evosep Proteomics addresses this challenge by standardizing pre-analytical workflows for mass spectrometry. This enables scalable, reproducible workflows, establishing a solid foundation for precision medicine, and accelerating therapeutic development.

Productivity from sample
to separation

Evosep Proteomics is a fully integrated, high-performance sample to separation solution for mass spectrometry, enabling standardized and scalable delivery of unbiased, actionable biological insights.

An Evosep White Paper

Standardizing Proteomics: From Sample to Separation

Inconsistencies in sample preparation and separation remain the biggest bottlenecks in modern proteomics. Read this white paper to explore how the Evosep Proteomics ecosystem standardizes the entire workflow—from input to LC-MS analysis—to deliver robust, reproducible data at scale.

Ease of use with standardized kits

Evokits, fully integrated with Evosep Lupo™, simplify sample preparation by combining all required reagents, consumables and Evotips with predefined, standardized workflows.

 

Evokit Digest (EV3802) is a standardized digestion kit that ensures consistent, high-quality sample preparation.

  • Magnetic bead-based protocol enables efficient clean-up and peptide recovery
  • Broad sample compatibility supports diverse biological sample types
  • Integrated process control monitors efficiency between sample prep batches
  • Preparation of up to 384 samples per run

Evokit SSC LC-MS (EV3801) monitors system suitability of LC-MS to ensure consistent performance.

  • Enables longitudinal studies with reliable monitoring across batches
  • Preparation of up to 96 samples per run

Evosep Webinar

Preparing for Next Generation Evosep Proteomics

available on demand

Watch our on-demand webinar explaining Evosep Proteomics.

Results you can trust

Traceability turns every run into a result you can trust – capturing samples, reagents, and workflows in a complete, auditable chain. Standardized, high‑quality data provides a strong foundation for AI‑driven insights.

Each action is linked directly to the user and sample, ensuring full accountability throughout the workflow. Real-time traceability captures data as you work, while a single sample list is used to generate the LC-MS sequence and can be exported to help avoid human errors.

Built-in checks and QC features support reliable performance, and all workflow steps, reagents, and consumables are fully tracked. Standardized workflows combined with saved and exportable records ensure consistency, accessibility, and confidence in every run.

User-linked records

— each action is linked to the user and sample

Real-time traceability

— data is captured as you work

Single source

— one sample list used to create the LC‑MS sequence. Export LC-MS sequence list to avoid human errors

Reliable

— built-in checks and QC

Fully covered

— all steps, reagents, and consumables tracked

Consistent and accessible

— standardized workflows with saved, exportable records

Walk-away workflow automation

Evosep Lupo enables consistent, high-quality results with minimal hands-on time.

Standardized, automated workflows reduce variability, while ready‑to‑analyse Evotips support seamless LC-MS integration. Built-in traceability and quality control ensure reproducible outcomes, supported by an intuitive interface that simplifies the setup.

Standardized kits require no preparation, with modules stored under the required conditions and ready for use. Built-in verification checks confirm correct positioning, orientation, and expiry to support error-free setup.

Full traceability includes batch tracking and easy access to Certificates of Analysis, while tailored .csv exports support seamless integration with your LC-MS setup. Controlled run order through Evotip positioning further helps ensure consistency and reproducibility across workflows.

 

 

 

Standardized kits

No preparation needed.
Modules stored under required conditions.

Error-free setup

Built-in verification of correct position, orientation and expiry.

Built-in QC

Automated monitoring kit and LC-MS performance.
Supports additional study QCs.

Full traceability

Batch tracking. Easy access to Certificate of Analysis.

MS ready export

Tailored .csv file for your setup. Controlled run order via Evotip positions.

Run standardized Evokit™ workflows with minimal hands-on time – reducing variability, simplifying operation, and freeing up time to focus on results.

Want to know more?

Our team is ready to help you find the method fitting your research need.

Robust workflow integration

Evotip Pure™ combines desalting and LC-MS sample introduction in one high efficiency step – delivering clean, ready-to-run samples with robust storage stability. The standardized output of Evokits and Evosep Lupo workflows ensures consistent, scalable sample preparation with reduced hands-on time and cost-per-sample. By stabilizing samples on the Evotip, bottlenecks are removed and you can scale workflows with confidence from small studies to high-throughput operation.

Increased productivity with standardized workflows

Standardizing the workflow reduces complexity and variability, replacing fragmented, multi-step processes with a consistent, integrated approach – whether running a few samples or operating at large scale.

This enables more reproducible results, fewer manual touchpoints, and more efficient use
of time and resources across the entire sample-to-data workflow.

Seamless connections

Evosep Lupo standardizes sample preparation and exports ready-to-run sequence lists with embedded QCs for vendor software.

Evosep Eno™ then connects seamlessly to leading mass spectrometers – enabling a consistent, low-setup workflow with built-in system suitability verification.

DOWNLOAD OUR MATERIAL

EVOSEP PROTEOMICS – Standardized Tools from Sample to Separation
Standardized sample preparation at scale with Evokits and Evosep Lupo
Evosep Proteomics: A standardized ecosystem from sample to separation
The Era of
Industrial Proteomics

The Open Innovation Initiative

In 2025, we launched the Open Innovation Initiative – a transparent, community-driven development effort with a mission to solve one of the most persistent challenges in LC-MS-based proteomics: sample preparation.

Learn about the initiative and follow our development journey here:

Get access to announcements, scientific insights, a look inside our company culture, upcoming events and much more!

Want to know more?

Our team is ready to help you find the method fitting your research need. Fill out our contact form and we will get back to you as soon as possible

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