EVOSEP Eno: EV1500

Evosep Eno is an easy-to-use, robust and reliable chromatographic solution for high performance and standardized proteomics, preparing for next generation workflow integration.

Next generation insights with Evosep Eno

LC-MS based proteomics is not just about individual technologies. It covers the entire workflow from sample preparation to data acquisition – ensuring sensitivity, reliability, and speed.

The Evosep Eno is a standardized platform designed for robustness and high throughput, integrating sample preparation with LC-MS analysis to streamline and optimize your entire workflow – not just individual performance metrics.

Maximum reliability: Designed to keep your research on track with out-of-the-box productivity, providing close to 100% uptime.

Cost-efficient: An affordable solution lowering the cost-per-sample by 64% while increasing MS utilization 29%

Patented approach: Innovative sample introduction and separation technology for seamless, efficient operation (EP3519808B1, EP3519807B1, US12298284B)

    Next generation insights with Evosep Eno

    LC-MS based proteomics is not just about individual technologies. It covers the entire workflow from sample preparation to data acquisition – ensuring sensitivity, reliability, and speed.

    The Evosep Eno is a standardized platform designed for robustness and high throughput, integrating sample preparation with LC-MS analysis to streamline and optimize your entire workflow – not just individual performance metrics.

    Maximum reliability: Designed to keep your research on track with out-of-the-box productivity, providing close to 100% uptime.

    Cost-efficient: An affordable solution lowering the cost-per-sample by 64% while increasing MS utilization 29%

    Patented approach: Innovative sample introduction and separation technology for seamless, efficient operation (EP3519808B1, EP3519807B1, US12298284B)

      Available on demand

      Beginner’s guide to Evosep

      Discover how to boost efficiency and simplify your LC-MS workflows with Evosep.

      Whether you’re just getting started or exploring new ways to streamline your proteomics setup, this session provides practical insights for users at any experience level.

      Learn how Evosep’s intuitive, automation-driven technology makes LC-MS–based proteomics accessible, reliable, and easy to integrate into your everyday lab routines.

        CHROMATOGRAPHY MATTERS – BOOST YOUR LC-MS PERFORMANCE

        Chromatography lays the foundation for good MS performance, and improvement in the chromatography is directly translated into improved MS performance.

        The Evosep Eno deliver up to 40% gain in precursor coverage compared to Evosep One, independent of downstream MS platform. The gain is mostly pronounced at that faster methods, where MS performance is pushed to the limits and thus becomes more sensitive to chromatographic performance. Altogether, standardized chromatographic improvements on the Evosep Eno gives you:

        •  Peak symmetry improved with up to 35%

        • 20% sharper peaks at base, leading to higher peak capacity

        • Up to 80% better retention time reproducibility

        • Significantly improved intensity and quantification

          Short learning curve and ease-of-use

          The versatility and ease-of-use of the Evosep Eno benefits any type of experiment, from multiple, smaller projects to the continuous analysis of large sample cohorts.

          You will instantly become an expert on the instrument and achieve cutting-edge performance – simply follow the listed column and emitter specifications to setup the method to confirm performance and reproducibility using the individual method application notes.

          Short learning curve and ease-of-use

          The versatility and ease-of-use of the Evosep Eno benefits any type of experiment, from multiple, smaller projects to the continuous analysis of large sample cohorts.

          You will instantly become an expert on the instrument and achieve cutting-edge performance – simply follow the listed column and emitter specifications to setup the method to confirm performance and reproducibility using the individual method application notes.

          A green transition for LC-MS based proteomics

          The Evotip simplifies sample handling from digestion to separation, reducing the number of single-use plastic tips needed to load a single sample.

          The Evotip allows the Evosep Eno to handle up to 500 samples per day, using 79% less solvent and 35% less plastic per sample compared to a traditional nLC. During sample preparation, the sample is loaded onto the Evotip, eliminating the need for extra consumables like vials, pipette tips, and solvents for elution and re-suspension.

          Additionally, the minimal carryover of Evotips reduces or eliminates the necessity for blank runs during experiment setup, leading to significant savings in liquid organic waste and electricity usage. 

          Whisper Zoom methods sets a new standard

          Whisper Zoom delivers unparalleled sensitivity for highly versatile applications. These robust methods enable high-throughput analysis for inter-laboratory studies, with a short learning curve that facilitates rapid method adaptation.

          This cutting-edge performance addresses the increasing need for scalability, ease-of-use, and robustness, allowing researchers to quickly adopt high-sensitivity workflows with minimal training.

          By maximizing recovery and achieving superior chromatographic performance, Whisper Zoom sets a new standard in proteomics research.

          Versatility through standardized methods

          The Evosep Eno, with its six standard methods, supports a range of use cases from comprehensive proteome analysis to ultra high-throughput single-shot analysis.

          It redefines consistency and efficiency in proteomics workflows with optimized methods and dedicated columns, ensuring reproducible performance and simplifying application support.

          By minimizing overhead time, it maximizes mass spectrometer utilization, generating more data in less time. Focused on accelerating MS development, it empowers labs to push the boundaries of sensitivity, scalability, and throughput without compromise.

          Whisper Zoom methods sets a new standard

          Whisper Zoom delivers unparalleled sensitivity for highly versatile applications. These robust methods enable high-throughput analysis for inter-laboratory studies, with a short learning curve that facilitates rapid method adaptation.

          This cutting-edge performance addresses the increasing need for scalability, ease-of-use, and robustness, allowing researchers to quickly adopt high-sensitivity workflows with minimal training.

          By maximizing recovery and achieving superior chromatographic performance, Whisper Zoom sets a new standard in proteomics research.

          On demand webinars

          Discover Proteomics at your own pace

          Explore our large collection of on-demand webinars, covering everything from beginner guides to advanced workflows with Evosep. In each webinar you can hear directly from our users as they share their research and experiences with their Evosep instrument.

          Additional resources

          Get to know Evosep and our technology through the experiences of those using it daily. Discover all publications our users and collaboration partners or dive into our many applications and tech notes.

          DOWNLOAD OUR MATERIAL

          case study
          Next generation LC-MS based proteomcis – a new era of speed, scale and robustness
          application note
          Evosep Eno – new standards for routine, scalable and high-performance LC-MS based proteomics

          tech note

          Introducing Evosep Eno

          application note
          Reproducible, inter-laboratory, scalable and routine LC-MS based Proteomics – With Evosep Eno
          application note
          EVOTIP PURE FOR END-TO-END WORKFLOWS: A COST-EFFICIENT, SUSTAINABLE AND SCALABLE PROTEOMICS SOLUTION
          application note
          EVOTIP PURE BRINGS INNOVATIVE SAMPLE STORAGE AND INTRODUCTION TO HIGH-SENSITIVITY AND SCALABLE LC-MS WORKFLOWS

          application note
          EVOTIP PURE SIMPLIFIES WORKFLOWS WITH EXCELLENT REPRODUCIBILITY, STORAGE AND RECOVERY

          brochure
          EVOSEP Eno:
          A Standardized Separation
          Tool for proteomics

          Want to know more?

          Our team is ready to help you find the method fitting your research need. Fill out our contact form and we will get back to you as soon as possible

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