A recent study from the Olsen group at University of Copenhagen, has capitalized on the recent developments in both high sensitivity instrumentation and sample preparation methods to perform single-cell pSILAC experiments providing functional information on protein turnover at the single-cell level.
Plasma proteomics, key in biomarker discovery, faces challenges. Evosep One simplifies workflow, enhances reproducibility, reduces costs, and speeds up analysis with automated Evotip loading, revolutionizing research potential and clinical outcomes.
This manuscript, authored by the Olsen group at the Novo Nordisk Foundation Center for Protein Research, describes technological advancements that set a new standard for scalable single-cell proteomics. By comprehensively addressing the entire workflow, the first commercially available solution for single-cell proteomics has become a reality, enabling the identification of more than 5,000 proteins from a single cell.
