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Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation

by Eva Bryderup

In this publication, the Mann group in Münich describes their innovative workflow for true single-cell proteomics. They apply a nearly loss-less miniaturized sample preparation workflow to our robust Whisper100 40SPD method and combine it with diaPASEF on a modified...

ABPP-HT – high-throughput activity-based profiling of deubiquitylating enzyme inhibitors in a cellular context

by Eva Bryderup

This publication from University of Oxford led by Adan Pinto-Fernandez, describes a new methodology named ABPP-HT (high-throughput-compatible activity-based protein profiling), implementing a semi-automated proteomic sample preparation workflow that increases the...

diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition

by Eva Bryderup

A collaboration led by the Mann group at the Max Planck Institute for Biochemistry, Münich describes the development of the latest addition to the PASEF technology. The diaPASEF workflow combines the advantages of DIA such as high degree of reproducibility and data...

High throughput proteome and phosphorpoteome sample processing coupled to fast gradient DIA

by Eva Bryderup

High throughput workflows for proteomics

Tech note: Evosep One: A gradient off-set focusing HPLC instrument for robust and high throughput proteomics

by Eva Bryderup

Evosep One descriptive technical note
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    Webinar: Whisper is coming

    Whisper is Here

    15/12/2020j/n/Y4:00pm CET2020-12-15T15:00:00Zg:ia T1 hour
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    In this webinar, we will introduce our next addition to our dynamic environment of specialized applications, EVOSEP+. We are developing a set of nanoflow methods for standard Evosep One hardware, which builds on a robust platform allowing for several thousand uninterrupted injections at very low flow rates. We will demonstrate the expected increase in sensitivity and benchmark the performance directly against our established standard methods.

     

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    • Events
      • Webinars
      • US HUPO 2021
    • Shop
    • products
      • Evosep One
      • Evotip
      • Columns and emitters
    • Methods
      • Standard methods
        • 300 SPD
        • 200 SPD
        • 100 SPD
        • 60 SPD
        • 30 SPD
      • EVOSEP+
        • Whisper 40SPD
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        • Extended method
    • Applications
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