Standardizing single cell proteomics with the Chip-Tip workflow

Proteins are the most dynamic molecules in the body, directly influencing cellular health and function. They are also the primary targets for most therapeutic treatments. Through proteomics, we can gain valuable insights into drug efficacy and safety by monitoring proteins in real-time. Significant progress has been made in this field over the past few decades, with recent technological advancements – particularly in the last five years – dramatically increasing both the speed and robustness of proteomics.

Complete automated sample preparation workflow for scalable Clinical Proteomics with Evotip: A Game-Changer for Biomarker Discovery

Proteomics has revolutionized the field of biomarker discovery, offering unprecedented insights into cellular processes and disease mechanisms. However, as mass spectrometry (MS) technology advances, the bottleneck has shifted to the pre-analytical sample preparation phase. Evosep’s innovative solution addresses this challenge head-on with a fully automated, scalable workflow leveraging the Evotip platform.

Advancements in Technology Setting new Standards for Scalable Single-Cell Proteomics: Identification of Over 5,000 Proteins in a Single HeLa Cell

This manuscript, authored by the Olsen group at the Novo Nordisk Foundation Center for Protein Research, describes technological advancements that set a new standard for scalable single-cell proteomics. By comprehensively addressing the entire workflow, the first commercially available solution for single-cell proteomics has become a reality, enabling the identification of more than 5,000 proteins from a single cell.

Pop-up Bot
Chat