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High sensitivity dia-PASEF proteomics with DIA-NN and FragPipe

by Eva Bryderup

The Ralser and Nesvizhskii groups introduce the latest addition to the DIA-NN software with a neural network-based ion mobility module. DIA-NN was originally conceived to maximize the performance of fast proteomics experiments and here they demonstrate the...

Application of diaPASEF for high-throughput and high-sensitivity proteomics with the Evosep One

by Eva Bryderup

Proteomics workflows have become increasingly successful in the characterization of complex proteomes in great depth. Application to large sample cohorts requires a high degree of reproducibility and data completeness, which makes DIA workflows interesting.

diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition

by Eva Bryderup

A collaboration led by the Mann group at the Max Planck Institute for Biochemistry, Münich describes the development of the latest addition to the PASEF technology. The diaPASEF workflow combines the advantages of DIA such as high degree of reproducibility and data...

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  • summer quiz
  • Events
    • Conferences
    • ASMS2022
    • webinars
  • Shop
  • products
    • Evosep One
    • Evotip
    • Columns and emitters
  • Methods
    • Standard methods
      • 300 SPD
      • 200 SPD
      • 100 SPD
      • 60 SPD
      • 30 SPD
    • EVOSEP+
      • Extended method
      • High organic method
      • Whisper 40 SPD
      • Whisper 20 SPD
  • Applications
    • Antimicrobial resistance
    • Automation
    • Clinical research
    • COVID-19
    • DIA
    • Drug Discovery
    • FFPE tissue analysis
    • Host cell protein
    • PLASMA
    • PROTEIN-PROTEIN INTERACTIONS
    • Single cell proteomics
    • TARGETED WORKFLOWS
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