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Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

by Eva Bryderup

This publication by the Costa group describes the mechanism whereby the Dbf4 dependent kinase selectively targets fully loaded MCM double hexamers on the path to helicase activation, and uncover the mechanism whereby the checkpoint kinase Rad53 blocks this...

Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19

by Eva Bryderup

This publication by the Zinkernagel group, assess the influence of COVID-19 plasma hypercytokinemia on the functional responses of myeloid immune cells upon bacterial challenges from acute-phase COVID-19 patients and their corresponding recovery-phase. We show that a...

Data independent acquisition enables deep and fast label-free dynamic organellar mapping

by Eva Bryderup

This publication by the Borner group, describes a DIA workflow to establish organellar maps, which combines cell fractionation and shotgun proteomics into a profiling analysis of subcellular localization. They apply this to HeLa cells and investigate changes in...

Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk

by Eva Bryderup

This publication, led by the Trøseid group at Oslo University Hospital investigates the potential role of plasma extracellular vesicles (EVs) in relation to gut microbiota alterations and low-grade endotoxemia in HIV and type 2 diabetes.

DebaryOmics: an integrative –omics study to understand the halophilic behaviour of Debaryomyces hansenii

by Eva Bryderup

This publication by the Martinez group at the Technical University of Denmark, presents the first global phosphoproteomics analysis in Debaryomyces hansenii, a non-conventional yeast considered to be a well-suited option for a number of different industrial...
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  • summer quiz
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    • Evosep One
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    • Standard methods
      • 300 SPD
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      • 100 SPD
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    • EVOSEP+
      • Extended method
      • High organic method
      • Whisper 40 SPD
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