This publication by the Costa group describes the mechanism whereby the Dbf4 dependent kinase selectively targets fully loaded MCM double hexamers on the path to helicase activation, and uncover the mechanism whereby the checkpoint kinase Rad53 blocks this...
This publication by the Zinkernagel group, assess the influence of COVID-19 plasma hypercytokinemia on the functional responses of myeloid immune cells upon bacterial challenges from acute-phase COVID-19 patients and their corresponding recovery-phase. We show that a...
This publication by the Borner group, describes a DIA workflow to establish organellar maps, which combines cell fractionation and shotgun proteomics into a profiling analysis of subcellular localization. They apply this to HeLa cells and investigate changes in...
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