LITERATURE ROOM

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TitleMaterialYearAuthorsOrganizationEvosep methodMS instrumentationLearn Morehf:tax:evosep_methodhf:tax:ms_vendor
Systematic optimization of automated phosphopeptide enrichment for high-sensitivity phosphoproteomics2025Patricia Bortel, Ilaria Piga, Claire Koenig, Christopher Gerner, Ana Martinez del Val, Jesper V. OlsenDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Austria

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Global analysis of protein turnover dynamics in single cells2025Pierre Sabatier, Zilu Ye, Maico Lechner, Ulises H. Guzmán, Christian M. Beusch, Fabiana Izaguirre, Anjali Seth, Olga Gritsenko, Sergey Rodin, Karl-Henrik Grinnemo, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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A Multiyear Longitudinal Harmonization Study of Quality Controls in Mass Spectrometry Proteomics Core Facilities2025Andrea Schuhmann, Damarys Loew, Karl Mechtler, Mariette Matondo, Mandy Rettel, Dominic Helm, Francis Impens, Simon Devos, Anna Shevchenko, Paolo Nanni, Eduard SabidóCentre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation2025Yingqian Li, Natalie Proost, Marieke van de Ven, Olaf van Tellingen, Onno B. Bleijerveld, John B.A.G. Haanen, Johanna Olweus, Reuven AgamiDivision of Oncogenomics, Oncode institute, the Netherlands Cancer Institute, Amsterdam, the Netherlands

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FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains2025Nicholas Norris, Cesar L. Moreno, Joshua W. C. Maxwell, G. Gregory Neely, Richard J. Payne, Melkam A. Kebede, Ramona J. Bieber Urbauer, Freda H. Passam, Mark Larance & Robert S. HaltiwangerComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA

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Biofabrication of anisotropic articular cartilage based on decellularized extracellular matrix2025Anna Puiggalí-Jou, Isabel Hui, Lucrezia Baldi, Rea Frischknecht, Maryam Asadikorayem, Jakub Janiak, Parth Chansoria, Maxwell C McCabe, Martin J Stoddart, Kirk C Hansen, Karen L Christman and Marcy Zenobi-WongTissue Engineering + Biofabrication Laboratory, Department of Health Sciences & Technology, ETH Zürich, Zürich, Switzerland

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eIF2α Phosphorylation-ATF4 Axis-Mediated Transcriptional Reprogramming Mitigates Mitochondrial Impairment During ER Stress2025Hien Thi Le, Jiyoung Yu, Hee Sung Ahn, Mi-Jeong Kim, In Gyeong Chae, Hyun-Nam Cho, Juhee Kim, Hye-Kyung Park, Hyuk Nam Kwon, Han-Jung Chae, Byoung Heon Kang, Jeong Kon Seo, Kyunggon Kim, Sung Hoon BackSchool of Biological Sciences, University of Ulsan, Ulsan, Korea

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Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes2025Diana Samodova, Evelina Stankevic, Mathilde Sonne Søndergaard, Naiyu Hu, Tarunveer S. Ahluwalia, Daniel R. Witte, Daniel Belstrøm, Anniek Frederike Lubberding, Pratik D. Jagtap, Torben Hansen & Atul S. DeshmukhNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

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Modeling the acutely injured brain environment in vitro2025Rocío Bartolomé,Alessia Ferrarini, Juan Antonio López, Elisa Murenu, BenediktBerninger, Felipe Ortega, Magdalena Götz, Christophe Heinrich,Sergio GascónDepartment of Molecular, Cellular and Developmental Neurobiology, Cajal Institute – CSIC, Spain

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Functional and Potential BioactiveHealth Benefits of Selected MicroalgalHydrolysates Assessed In Silico and InVitro2025Elena Aurino, Leticia Mora, Antonio Marzocchella, Christina M. Kuchendorf, Bärbel Ackermann and Maria HayesDipartimento di Ingegneria Chimica, dei Materiali, e della Produzione Industriale, Università degli Studi di Napoli ‘Federico II’, Naples, Italien

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Determination of collagen types and mineral contents in fish skin and collagen-containing skin-derived protein hydrolysates before and after in vitro simulated digestion2025Min Wang, Yixuan Liu, Noelia Pallarés, Zouhir el Marsni, Katerina Kousoulaki, and Francisco J. BarbaResearch group in Innovative Technologies for Sustainable Food (ALISOST), Department of Preventive Medicine and Public Health, Valencia, Spain

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Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome2025Veronica Muratore, Claudia Guinea-Pérez, Álvaro Serrano, Coralia Pérez, Sandra CanoLópez, Ainhoa Urcullu, Mikel Azkargorta, Ibon Iloro, Carles Galdeano, Jordi Juárez-Jiménez, Ugo Mayor, Felix Elortza, Rosa Barrio, James D. SutherlandCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research 10 and Technology Alliance (BRTA), Derio, Spain

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COA5 has an essential role in the early stage of mitochondrial complex IV assembly2025Jia Xin Tang, Alfredo Cabrera-Orefice, Jana Meisterknecht, Lucie S Taylor, Geoffray Monteuuis, Maria Ekman Stensland, Adam Szczepanek, Karen Stals, James Davison, Langping He, Sila Hopton, Tuula A Nyman, Christopher B Jackson, Angela Pyle, Monika Winter,Mitochondrial Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK

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Centromere inactivation during aging can be rescued in human cells2025Sweta Sikder, Songjoon Baek, Truman Mcneail, Yamini DalalCenter for Cancer Research, National Cancer Institute/NIH, Bethesda, MD 20892, USA, Saint Olaf College, 1520 St. Olaf Avenue, Northfield, MN 55057, USA

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AUTO-SP: automated sample preparation for analyzing proteins and protein modifications2025T. Mamie Lih, Liyuan Jiao, Lijun Chen, Jongmin Woo, Yuefan Wang, Hui ZhangDepartment of Pathology, John Hopkins University School of Medicine, Baltimore, Maryland, United States, Department of Oncology, Sidney Kimmel Cancer Center at John Hopkins Medical Institutions, Baltimore, Maryland, United States, Department of Urology, J

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30-spdthermo-orbitrap-exploris-480
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation2025Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin RittingerProteomics Science Technology Platform, The Francis Crick Institute, London, UK, Molecular Structure of Cell Signalling Laboratory, The Francis Crick Institute, London, UK, Crick-GSK Biomedical LinkLabs, GSK, Stevenage, Hertfordshire, UK,

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Multi-omics analysis of keratinocytes reveals dermokine-dependent regulation of cell-cell adhesion via p1202025Vahap Canbay, Till Wüstemann, Weihua Tian, Tobias A. Beyer, Camilla Reiter Elbæk, Michael Stumpe, Gaetana Restivo, Chatpakorn Christiansen, Anabel Migenda Herranz, Susanne Mailand, Jürg Hafner, Rune Busk Damgaard, Steffen Goletz, Jörn Dengjel, Ulrich aufDepartment for Bioengineering and Biomedicine, Technical University of Denmark, 2800, Copenhagen, Denmark.

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Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics2025Zilu Ye, Pierre Sabatier, Leander van der Hoeven, Maico Y. Lechner, Teeradon Phlairaharn, Ulises H. Guzman, Zhen Liu, Haoran Huang, Min Huang, Xiangjun Li, David Hartlmayr, Fabiana Izaguirre, Anjali Seth, Hiren J. Joshi, Sergey Rodin, Karl-Henrik GrinnemoNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark, ,

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IP-to-MS: An Unbiased Workflow for Antigen Profiling2025Stephanie Biedka, Svitlana Yablonska, Xi Peng, Duah Alkam, Mara Hartoyo, Hannah VanEvery, Daniel J. Kass, Stephanie D. Byrum, Kunhong Xiao, Yingze Zhang, Robyn T. Domsic, Robert Lafyatis, Dana P. Ascherman, Jonathan S. MindenImpact Proteomics, LLC., Pittsburgh, Pennsylvania 15206, United States,,

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Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures2025Caroline R. Espada, Christian Anthon, Rubens D.M. Magalhães, José Carlos Quilles Junior, Natalia M.M. Teles, Fabiano Pais, Lissur A. Orsine, Letícia de Almeida, Tânia P. A. Defina, Adam Dowle, Jan Gorodkin, Pegine B. Walrad, Angela K. CruzDepartment of Cell and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo FMRP-USP, Ribeirão Preto, São Paulo, Brasil

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Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics2025Xiang Zheng, Andreas Mund, Matthias MannNovo Nordisk Foundation Center for Protein Research, University of Copenhagen 2200, Copenhagen, Denmark,

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Comparison of the amyloid plaque proteome in Down syndrome, early-onset Alzheimer’s disease, and late-onset Alzheimer’s disease2025Mitchell Martá‑Ariza, Dominique F. Leitner, Evgeny Kanshin, Jianina Suazo, Ana Giusti Pedrosa, Manon Thierry, Edward B. Lee, Orrin Devinsky, Eleanor Drummond, Juan Fortea, Alberto Lleó, Beatrix Ueberheide, Thomas WisniewskiDepartment of Neurology, NYU Grossman School of Medicine, New York, NY, USA,

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Identification of novel Kv1.3 channel-interacting proteins using proximity labelling in T-cells2025Dilpreet Kour, Christine A. Bowen, Upasna Srivastava, Hai M. Nguyen, Rashmi Kumari, Prateek Kumar, Amanda D. Brandelli, Sara Bitarafan, Brendan R Tobin, Levi Wood, Nicholas T. Seyfried, Heike Wulff, Srikant RangarajuDepartment of Neurology, School of Medicine, Yale University, New Haven (CT), USA, Center for Neurodegenerative Diseases, Emory University, Atlanta (GA), USA, Department of Biochemistry, Emory University, Atlanta (GA), USA

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Proteomics Reveals Distinctive Host Cell Protein Expression Patterns in Fed-Batch and Perfusion Cell Culture Processes2025Ansuman Sahoo, Taku Tsukiadate, Bor-Ruei Lin, Erin Kotzbauer, Jason Houser, Misaal Patel, Xuanwen Li, Sri Ranganayaki MadabhushiBiologics Process Research & Development, Merck & Co., Inc., Rahway, New Jersey, USA 2 Analytical Research & Development Mass Spectrometry, Merck &Co., Inc., Rahway, New Jersey, USA,

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Molecular Mechanisms of Acanthamoeba castellanii Response to Different Sources of Oxidative Stress2025Kateřina Ženíšková, Pavel Stopka, Tania Martín-Pérez, Guillaume Chevreux, Maria Grechnikova, Eliška Drncová, Ronald Malych, Jan Mach, Julia Walochnik, Jean-Michel Camadro, Robert SutakDepartment of Parasitology, Faculty of Science, BIOCEV, Charles University, Vestec 25250, Czech Republic

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Pupylation-based proximity labeling reveals regulatory factors in cellulose biosynthesis in Arabidopsis2025Shuai Zheng, Lise C. Noack, Ouda Khammy, Andreas De Meyer, Ghazanfar Abbas Khan, Nancy De Winne, Dominique Eeckhout, Daniël Van Damme, Staffan PerssonCopenhagen Plant Science Center, Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Intestinal enteroendocrine cell subtype differentiation and hormone production in zebrafish2025Margaret Morash, Richard G. Kay, Erik J. Soderblom, Grace H. MacLean, Jia Wen, Peyton J. Moore, Colin R. Lickwar, Fiona M. Gribble, Frank Reimann, Rodger A. Liddle, John F. RawlsDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.

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Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth2025Jonathan A. Chapman, Andrea C. Masi, Lauren C. Beck, Hannah Watson, Gregory R. Young, Hillary P. Browne, Yan Shao, Raymond Kiu, Andrew Nelson, Jenifer A. Doyle, Pawel Plamowski, Márton Lengyel, James P. R. Connolly, Christopher A. Lamb, Andrew Porter, TreNewcastle University, Translational and Clinical Research Institute, Newcastle upon Tyne, NE2 4HH, UK

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Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease2025Alejandro Pinto, Hazal Haytural, Cássio Morais Loss, Claudia Alvarez, Asude Ertas, Olivia Curtis, Alyssa R. Williams, Grayson Murphy, Ken Salleng, Sylvia Gografe, Ali Altıntaş, Tal Kafri, Romain Barres, Atul S. Deshmukh, Henriette van PraagStiles-Nicholson Brain Institute, Charles E. Schmidt College of Medicine, Florida Atlantic University, Jupiter, FL 33458, USA

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Histone methyltransferase DOT1L maintains identity and restricts cytotoxic potential of CD8 T cells2025Muddassir Malik, Willem-Jan de Leeuw, Muhammad Assad Aslam, Eliza Mari Kwesi-Maliepaard, Teun van den Brand, Bram van den Broek, Maxime Kempers, Liesbeth Hoekman, Nathalie Proost, Tibor van Welsem, Elzo de Wit, Jannie Borst, Heinz Jacobs, Fred van LeeuwenDivision of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands

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Challenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics2025Matt Spick, Cheryl M. Isherwood, Lee A. Gethings, Christopher J. Hughes, Matthew E. Daly, Hana Hassanin, Daan R. van der Veen, Debra J. Skene, Jonathan D. JohnstonSchool of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK

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Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies2025Georgia Mitsa, Livia Florianova, Josiane Lafleur, Adriana Aguilar-Mahecha, Rene P. Zahedi, Sonia V. del Rincon, Mark Basik, Christoph H. Borchers, Gerald BatistLady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montréal H3T 1E2, Canada, Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital and McGill University, Montréal H3T 1E2, C

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Modulation of biological activities in adipose derived stem cells by histone deacetylation2025Sallam Abdallah, Mouna Tabebi, Sawsan Qanadilo, Neserin Ali, Jing Wang, Pádraig D'Arcy, Wen Zhong, Folke Sjoberg, Moustafa Elmasry, Ahmed El-SerafiThe Department of Biomedical and Clinical Sciences (BKV), Lindköping University, Lindköping, Sweden

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30-spdbruker-timstof-pro
Discovery of Chemical Tools for Polysorbate-Degradative Enzyme Control in Biopharmaceutical Upstream Process via Multi-Omic Profiling of Host Cell Clones2025Taku Tsukidate, Ansum Sahoo, Geetanjali Pendyala, Rong-Sheng Yang, Jonathan Welch, Sri Madabhushi, Xuanwen LiAnalytical Research & Development Mass Spectrometry, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States.

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extended-methodtimstof-pro-2
The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice2025Irene Santos-García, Pablo Bascuñana, Mirjam Brackhan, María Villa, Ivan Eiriz, Thomas Brüning, Jens PahnkeTranslational Neurodegeneration Research and Neuropathology Lab, Department of Clinical Medicine (KlinMed), Medical Faculty, University of Oslo (UiO) and Section of Neuropathology Research, Department of Pathology (PAT), Clinics for Laboratory Medicine (K

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30-spdtimstof-pro-2
Harnessing Filamentous Fungi for Enzyme Cocktail Production Through Rice Bran Bioprocessing2025Ana M. Yélamos, Jose F. Marcos, Paloma Manzanares, Sandra GarriguesFood Biotechnology Department, Instituto de Agroquímica y Technología de Alimentos (IATA), Consejo Superior de Investigaciones Científicas (CSIC), Catedrático Augustín Escardino Benlloch 7, 46980, Valencia, Spain, ,

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100-spd 30-spdbruker-timstof-flex thermo-orbitrap-exploris-240
Characterisation of a Chondrus crispus Stakehouse Hydrolysate for Functional,Nutritional and Bioactive Benefits and Application as an Emulsifier in Baked Goods2025Dolly Bhati, Leticia Mora, Maria HayesFood BioSciences, Teagasc Food Research Centre, Dunsinea Lane, Ashtown, D15 DY05 Dublin, Ireland

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30-spdbruker-timstof-flex
Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth2025Zhongze Li, Minjae Kim, Jose Roberto da Silva Nascimento, Bertrand Legeret, Gabriel Lemes Jorge, Marie Bertrand, Fred Beisson Jay J. Thelen, Yonghua Li-BissonAix-Marseille Université, CEA, CNRS, Institute of Biosciences and Biotechnologies of Aix-Marseille, UMR 7265, CEA Cadarache, Saint-Paul-lez Durance, France

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30-spdtimstof-pro-2
Predicting Protein Pathways Associated to Tumor Heterogeneity by Correlating Spatial Lipidomics and Proteomics: The Dry Proteomic Concept2025Laurine Lagache, Yanis Zirem, Émilie Le Rhun, Isabelle Fournier, Michel SalzetUniv.Lille, Inserm, CHU Lille, U1192 – Proteomics Inflammatory Response Mass Spectrometry- PRISM, Lille, France

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A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma2025Kirit Singh, Matthew W. Foster, Marlene J. Violette, Annam: Corcoran, Kelly M, Hotchkiss, Chelsea O. Railton, Emily E. Blandford, Kathryn E. Blethen, Elizabeth L. Thomas, David M. Ashley, Annick Desjardins, Henry S. Friedman, Margaret O. Johnson, Allan FrThe Preston Robert Tisch Brain Tumor Center at Duke University; Durham, NC, US, Department of Neurosurgery, Duke University; NC, US, ,

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An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease2025Marcell Harhai, Mads M. Foged, Emeline Recazens, Miriam Lisci, Sylvain Chollet, Juan C. Landoni, Nora Laban, Saliana Manley, Jose Antonio Lopez-Escamez, Anna Lysakowski, Alexis A. JourdainDepartment of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Switzerland

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extended-methodbruker-timstof-pro
Milk-derived antimicrobial peptide GMp7: Disrupting protein networks for multi-target antibacterial inhibition and enhanced dairy preservation2025Jinze He, Hong Li, Yujuan Xu, Yufang Li, Tingting Yang, Xiaoyan Yu, Xue Yang, Aixiang Huang, Yuanshan Yu, Yanan ShiSericultural & Agri-Food Research Institute, Guandong Academy of Agricultural Sciences, Key Laboratory of Functional Foods, Ministry of Agriculture and Rural Affairs, Guangdong Key Laboratory of Agricultural Product Processing, Guangzhou, 510610, China

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30-spdtimstof-pro-2
A rapid genome-proteome approach to identify rate-limiting steps in the butyrate production pathway in probiotic Clostridium butyricum, CBM588.2025Liam Wood, Bunmi B. Omorotionmwan, Adam M. Blanchard, Adam Dowle, David Tooth, Tom S. Bailey, Ruth GriffinVaccines and Therapeutics Group, Biodiscovery Institute, School of Life Sciences, University of Nottingham, University Park, Nottingham, UK

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Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise2025Ben Stocks, Julia Prats Quesada, Anthony M. Mozzicato, Carolina Jacob, Simone Jensen, Kirstin A. McGregor, Jens Bangsbo, Juleen R. Zierath, Morten Hostrup, Atul S. DeshmukhPhosphoproteomic mass spectrometry analyses were performed by the Proteomics Research nfrastructure (PR) at the University of openhagen (UP), supported by the ovo ordisk Foundation (F) (gr

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30-spdtimstof-pro-2
C-terminal amides mark proteins for degradation via SCF–FBXO312025Hofmann, Lukas T. Henneberg, Moritz M. Pfleiderer, Annina Denoth-Lippuner, Fillip Kalčic, Ajse S. Nievergelt, Marwa Peters Al-Bayati, Nikolaos D. Sidiropoulos, Viola Beier, Matthias Mann, Sebastian Jessberger, Martin Jinek, Brenda A. Schulman, Jeffrey W.Institute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland, Laboratory for Organic Chemistry, Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technolog

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30-spdtimstof-pro-2
Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha2025Lawson, Andrew Michael Frey, Iglika Ivanova, Eva Adam, Christopher J. Lord, Simon Cockell, Jonathan Coxhead, Nikoletta Negy, David Adams, Marta Szell, Matthias Trost, Muzlifah Haniffa, Simon P. Mackay, Neil Perkins, Neil RajanTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

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Measurements of Iodination in Thyroglobulin: A Step Toward the Next Generation of Thyroid Cancer Monitoring2025Anthony Maus, Chris Thompson, Stefan K G GrebeDepartment of Laboratory Medicine and Pathology, Division of Clinical Biochemistry and Immunology, Mayo Clinic, Rochester, MN 55905, USA

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extended-methodthermo-orbitrap-exploris-480
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus2025Fátima Cano-Cano, Almudena Lara-Barea, Álvaro Javier Cruz-Gómez, Francisco Martín-Loro, Laura Gómez-Jaramillo, María Carmen González-Rosa, Mª Carmen Durán-Ruiz, Ana I Arroba, Manuel Aguilar-DiosdadoDiabetes Mellitus Laboratory, Institute of Research and Biomedical Innovation of Cadiz (INiBICA), Cádiz, Spain

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30-spdbruker-timstof-pro
Harnessing the Potential of Human Breast Milk to Boost Intestinal Permeability for Nanoparticles and Macromolecules2025Si Naftaly, Tapz Pery, Rawan Mhajne, Areen Ashkar, Maya Davidovich-Pinhas, Assaf ZingerLaboratory for Bioinspired Nano Engineering and Translational Therapeutics, Department of Chemical Engineering, Technion−Israel Institute of Technology, Haifa 3200003, Israe

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extended-methodthermo-orbitrap-exploris-480
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma2025Sonja Kabatnik, Xiang Zheng, Georgios Pappas, Sophia Steigerwald, Matthew P Padula, Matthias MannNovo Nordisk Foundation Center for Protein Research, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark

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Multiple classes of antigen contribute to the antigenic landscape of mesothelioma2025Kirti Pandey, Pouya Faridi, Rochelle Ayala, Y.C. Gary Lee, Ebony Rouse, Sanjay S.G. Krishna, Ian Dick, Alec Redwood, Bruce Robinson, Jenette Creaney, Anthony W. PurcellDepartment of Biochemistry and Molecular Biology and Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia

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Discovery of a distinct BAM complex in the Bacteroidetes2025Augustinas Silale, Mariusz Madej, Katarzyna Mikruta, Andrew M. Frey, Adam J. Hart, Arnaud Baslé, Carsten Scavenius, Jan J. Enghild, Matthias Trost, Robert P. Hirt, Bert van den BergBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK, Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland

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Master control genes in the regeneration of rod photoreceptors from endogenous progenitor cells in zebrafish retina2025Eyad Shihabeddin, Abirami Santhanam, Stephan Tetenborg, Alexandra L. Aronowitz, Haichao Wei, Guoting Qin, Chengzhi Cai, Jiaqian Wu, John O'BrienDepartment of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States

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Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes2025Jarne, Daniel Perez-Zsolt, Roger Badia, Eva Riveira-Muñoz, Edurne Garcia-Vidal, Lluís Revilla, Sandra Franco, Ferran Tarrés-Freixas, Núria Roca, Gerado Ceada, Karl Kochanowski, Dália Raïch-Regué, Itziar Erkizia, Rytis Boreika, Antoni E. Bordoy, Laia SolerIrsiCaixa, Germans Trias i Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Spain

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Identifying receptor kinase substrates using an 8,000 peptide kinase client library enriched for conserved phosphorylation sites2025Daewon Kim, Gabriel Lemes Jorge, Chunhui Xu, Lingtao Su, Sung-Hwan Cho, Nagib Ahsan, Dongqin Chen, Lijuan Zhou, Marina A. Gritsenko, Mowei Zhou, Jinrong Wan, Ljiljana Pasa-Tolic, Dong Xu, Laura E. Bartley, Jay J. Thelen, Gary StaceyDivision of Plant Science & Technology, C.S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA, Division of Biochemistry and Interdisciplinary Plant Group, C.S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211

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whisper-40spdtimstof-pro-2
Spatial Proteomics by Parallel Accumulation-Serial Fragmentation Supported MALDI MS/MS Imaging: A First Glance Into Multiplexed and Spatial Peptide Identification2025Mujia Jenny Li, Larissa Chiara Meyer, Nadine Meier, Jannik Witte, Maximilian Maldacker, Adrianna Seredynska, Julia Schueler, Oliver Schilling, Melanie Christine FöllInstitute for Surgical Pathology, Faculty of Medicine, University Medical Centre Freiburg, University of Freiburg, Freiburg, Germany

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CyanoTag: Discovery of protein function facilitated by high-throughput endogenous tagging in a photosynthetic prokaryote2025Abigail J. Perrin, Matthew Dowson, Katharine Davis, Onyou Nam, Adam A. Dowle, Grant Calder, Victoria J. Springthorpe, Guoyan Zhao, Luke C. M. MackinderDepartment of Biology, University of York, York Y010 5DD, UK

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Cell Surface Proteomics for Radioligand Therapies: Deep Profiling of Cancer Cell Surface Receptors2025SapientSapient

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Multicenter Longitudinal Quality Assessment of MS-Based Proteomics in Plasma and Serum2025Christine König, Teresa K. Barth, Julia Mergner, Christina Ludwig, Johanna Tüshaus, Pieter Giesbertz, Stephan Breimann, Lisa Schweizer, Torsten Müller, Georg Kliewer, Ute Distler, David Gomez-Zepeda, Oliver Popp, Di Qin, Daniel Teupser, Jürgen Cox, Axel IMetabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich 80939, Germany

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Proximity labeling of the Tau repeat domain enriches RNA-binding proteins that are altered in Alzheimer’s disease and related tauopathies2025Sarah M. Shapley, Anantharaman Shantaraman, Masin A. Kearney, Eric B. Dammer, Duc M. Duong, Christine A. Bowen, Pritha Bagchi, Qi Guo, Srikant Rangaraju, Nicholas T. SeyfriedMedicine, Atlanta, Georgia, USA, Department of Biochemistry, Emory School of Medicine, Atlanta, Georgia, USA, Emory Integrated Proteomics Core, Emory School of Medicine, Atlanta, Georgia, USA, Department of Neurology, School of Medicine, Yale University,

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Extracellular vesicles enhance in vitro oocyte maturation2025Sofia Makieva, Mara D. Senz-de-Juano, Carmen Almiña, Stefan Bauersachs, Sandra Bernal-Ulloa, Min Xie, Ana G Velasco, Natalia Cervantes, Maike Sachs, Susanne E. Ulbrich, Birgitte LeenersDepartment of Reproductive Endocrinology, University Hospital Zurich, Zurich, Switzerland

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Precision in Tear Fluid Biomarker Discovery: Quantitative Proteomic Profiling of Small-Volume, Individual Samples Using Capillary Tube Collection2025Kyla Frenia, Yunxiang Fu, Maria A. Beatty, Kathleen C. Garwood, Jeremy Kimmel. Veena Raiji, Dipanjan Pan, David Bartlett, Leanne T. Labriola, Kunhong XiaoDepartment of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA 15260, USA

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Deep visual multi-omics profiling reveals mechanisms that underly cancer cell differentiation and aggressiveness in clear cell renal cell carcinoma2025Hella A. Bolck, Ede Migh, Andras Kriston, Natalia H. Zajac, Susanne Kreutzer, Tiberiu Totu, Peter Leary, Ferenc Kovacs, Dorothea Rutishauser, Sybille Pfammatter, Jonas Grossmann, Cassandra Litchfield, Marija Buljan, Niels J. Rupp, Peter Horvath, Holger MoDepartment of Pathology and Molecular Pathology, University Hospital Zürich and University of Zürich, Zürich, Switzerland

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Selecting optimal ZT Scan DIA acquisition methods on the ZenoTOF 7600+ system for quantitative proteomics2025Victoria South, Jonghae Youn, Ihor Batruch, Remco van Soest, Patrick PribilSCIEX UK, SCIEX USA, SCIEX Canada,

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Measurements of Iodination in Thyroglobulin: A Step Toward the Next Generation of Thyroid Cancer Monitoring2025Anthony Maus, Chris Thompson, Stefan K G GrebeDepartment of Laboratory Medicine and Pathology, Division of Clinical Biochemistry and Immunology, Mayo Clinic, Rochester, MN 55905, USA

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Spatially resolved proteomic signatures of atherosclerotic carotid artery disease2025Ankit Sinha, Nadja Sachs, Elena Kratz, Jessica Pauli, Sophia Steigerwald, Vincent Albrecht, Thierry Nordmann, Enes Ugur, Edwin H. Rodriguez, Marie-Luise Engl, Patricia Skowronek, Moritz von Scheidt, Hanna Winter, Daniela Branzan, Heribert Schunkert, LarsMax Planck Insitute for Biochemistry, Munich, Germany, German Centre for Cardiovascular and endovascular Surgery, TUM Klinikum, Technical University Munich, Munich, Germany

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Epitope Mapping with Sidewinder: An XL-MS and Structural Modeling Approach2025Joel Ströbaek, Di Tang, Carlos Gueto-Tettay, Alejandro Gomez Toledo, Berit Olofsson, Erik Hartman, Moritz Heusel, Johan Malmström, Lars MalmströmDepartment for Clinical Sciences Lund, Infection Medicine, Faculty of Medicine, Lund University, 221 84 Lund, Sweden

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CK2 directly controls CARD9 protein homeostasis2025Anand, Sabariya Selvam, Sayali Dagde, Emily Holzinger, Lauren Piasecki, Travis A. Pemberton, Emily Fu, McKenna Joint, Hayden Sandt, Ashish K. Singh, Tai Wang, Denise Cobb, Xiaochun Ni, Geraint H. M. Davies, Alan F. Corin, Sophie Roy, Stephen C. WilsonLead Discovery and Optimization, Discovery and Development Sciences, Bristol Myers Squibb, 250 Water St. Cambridge, MA, 02141 USA

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SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells2025Emma Valima, Vera Varis, Kseniia Bureiko, Joanna K. Lempiäinen, Anna-Mari Schroderus, Laura Oksa, Olli Lohi, Tuure Kinnunen, Markku Varjosalo, Einari A. Niskanen, Ville Paakinaho, Jorma J. PalvimoInstitute of Biomedicine, University of Eastern Finland, Kuopio, Findland

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Spatially resolved proteomic signatures of atherosclerotic carotid artery disease2025Ankit Sinha, Nadja Sachs, Elena Kratz, Jessica Pauli, Sophia Steigerwald, Vincent Albrecht, Thierry Nordmann, Enes Ugur, Edwin H. Rodriguez, Marie-Luise Engl, Patricia Skowronek, Moritz von Scheidt, Hanna Winter, Daniela Branzan, Heribert Schunkert, LarsMax Planck Insitute for Biochemistry, Munich, Germany, German Centre for Cardiovascular Research (DZHK) Partner site Munich Heart Alliance, Munich Germany

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The MAST kinase KIN-4 carries out mitotic entry functions of Greatwall in C. elegans2025Ludivine Roumbo, Batool Ossareh-Nazari, Suzanne Vigneron, Ioanna Stefani, Lucie Van Hove, Véronique Legros, Guillaume Chevreux, Benjamin Lacroix, Anna Castro, Nicholas Joly, Thierry Lorca, Lionel PintardUniversité Paris cité, CNRSInstitut Jacques Monod F-75013 Paris France

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Single-Cell Proteomics using Mass Spectrometry2025Amanda Momenzadeh, Jesse G. MeyerDepartment of Computational Biomedicine, Smidt Heart Institute, Board of Governors Innovation Center, Advanced Clinical Biosystems Research Institute Cedars Sinai Medical Center, Los Angeles CA 90048

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Secretome Analysis of Human and Rat Pancreatic Islets Co-Cultured with Adipose-Derived Stromal Cells Reveals a Signature with Enhanced Regenerative Capacities2025Erika Pinheiro-Machado, Bart J. de Haan, Marten A. Engelse, Alexandra M. SminkDepartment of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzerplein 1, 9713 GZ Groningen, The Netherlands, Leiden Transplant Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The N

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A Metabolic Complex Involved in Tomato Specialized Metabolism2025Varun Dwivedi, Ernest Okertchiri, Adam Yokom, Craig A. SchenckDepartment of Biochemistry, University of Missouri, Columbia, MO, USA, Interdisciplinary Plant Group, University of Missouri, Columbia, MO, USA

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Distinct Urinary Proteome Changes Across Estimated Glomerular Filtration Rate Stages in a Cohort of Black South Africans2025Siyabonga Khoza, Jaya A. George, Previn Naicker, Stoyan H. Stoychev, Rethabile J. Mokoena, Ireshyn S. Govender, June FabianDepartment of Chemical Patology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa

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Plasma proteome variation and its genetic determinants in children and adolescents2025Lili Niu, Sara Elizabeth Stinson, Louise Aas Holm, Morten Asp Vonsild Lund, Cilius Esmann Fonvig, Leonardo Coboccio, Jonas Meisner, Helene Bæk Juel, Joao Fadista, Maja Thiele, Aleksander Krag, Jens Christian Holm, Simon Rasmussen, Torben Hansen, MatthiasNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

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Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome2025Laura Merino-Cacho, Orhi Barroso-Gomila, Mónica Pozo-Rodríguez, Veronica Muratore, Claudia Guinea Pérez, Álvaro Serrano, Coralia Pérez, Sandra Cano-López, Ainhoa Urcullu, Mikel Azkargorta, Ibon Lioro, Carles Galdeano, Jordi Juárez-Jiménez, Ugo Mayor, FeliCenter for Cooperative Research in Biosciences (CIC Biogune), Basque Research and Technology Alliance (BRTA), 48160, Derio, Spain

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The influence of amniotic membrane proteins on corneal regeneration when delivered directly or using hydrogel platforms2025Ayla Basasoro, Javier Mendicute, Marta Rezola, Jorge Burgos, Mercedes Fernández, David Esporrín-Ubieto, Ana Sonzogni, Marcelo Calderón, Itxaso Calafel, Aitor Díaz, Juliana De Souza, Ana Aiastui, Mikel Azkarforta, Félix Elortza, Elena Vecino, Arantxa AceraHospital Universitario Donostia-San Sebastían, Spain

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Functionality and translation fidelity characterization of mRNA vaccines using platform based mass spectrometry detection2025Alyssa Q. Stiving, Benjamin W. Roose, Christopher Tubbs, Mark Haverick, Ashley Gruber, Richard R. Rustandi, Jesse Kuiper, Matthew Schombs, Hillary Schuessler, Xuanwen LiAnalytical Research and Development, Merck and Co., Inc, 126 E Lincoln Ave., Rahway, NJ, USA

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Differences in biomarker levels and proteomic survival prediction across two COVID-19 cohorts with distinct treatments2025Cecilie Bo Hansen, Maria Elizabeth Engel Møller, Laura Pérez-Alós, Simone Bastrup Israelsen, Lylia Drici, Maud Eline Ottenheijm, Annelaura Bach Nielsen, Nicolai J. Wewer Albrechtsen, Thomas Benfield, Peter GarredLaboratory of Molecular Medicine, Department of Clinical Immunology, Section 7631, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Lipid alterations in acute myocardial infarction are associated with gut microbiota2025Jiebin Zuo, Panpan Wang, Kewen Xue, Yuwen Tan, Ting Zhang, Yang Li, Feixiang He, Weikun Wu, Zhixiang Yan, Li Cong, Gang LiCardiac Surgery and Structural Heart Disease Unit of Cardiovascular Center, The Fifth Affiliated Hospital, Sun Yatsen University, Zhuhai, China

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Dissecting PADI6 function defines oocyte cytoplasmic lattices as regulatory hubs for fundamental cellular processes2025Jack P. C. Williams, Tania Auchynnikava, Afshan McCarthy, Obah A. Ojarikre, M. Teresa Bertran, Anne E. Weston, Dan Leonce, Jessica Olsen, Kathy K. Niakan, Mark Skehel, James M. A. Turner, Louise J. WalportProtein-Protein Interaction Laboratory, The Francis Crick Insitute, London, UK

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Dynamic In Vivo Mapping of the Methylproteome Using a Chemoenzymatic Approach2025Jonathan Farhi, Benjamin Emenike, Richard S. Lee, Kirti Sad, Dorelle V. Fawwal, Christian M. Beusch, Robert B. Jones, Ashish K. Verma, Celina Y. Jones, Maryam Foroozani, Monica Reeves, Kiran K. Parwani, Pritha Bagchi, Roger B. Deal, David J. Katz, Anita HDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States

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Implications of tissue specific STING protein flux and abundance on inflammation and the development of targeted therapeutics2025Thomas E. Angel, Zhuo Chen, Ahmed Moghieb, Sze-Ling Ng, Allison M. Beal, Carol Capriotti, Leonard Azzarano, Debra Comroe, Michael Adam, Patrick Moore, Bao Hoang, Kelly Blough, Joanne Kuziw, Joshi M. Ramanjulu, G. Scott PesirdisResearch and Development, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America

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Human skeletal muscle fiber heterogeneity beyond myosin heavy chains2025Roger Moreno-Justicia, Thibaux Van der Stede, Ben Stocks, jenni Laitila, Robert A. Seaborne, Alexia Van de Loock, Eline Lievens, Diana Samodova, Leyre Marín-Arrazia, Oksana Dmytriyeva, Robin Browaeys, Kim Van Vossen, Lukas Moesgaard, Nurten Yigit, JasperNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

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Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow2025Alejandro Gomez Toledo, Sounak Chowdhury, Elisabeth Hjortswang, James T. Sorrentino, Nathan E. Lewis, Anna Bläckberg, Simon Ekström, Sven Kjellström, Arman Izadi, Berit Olofsson, Pontus Nordenfelt, Lars Malmström, Magnus Rasmussen, Johan MalmströmDivison of Infection Medicine, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden

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Assessing customized multivalent chemokine-binding peptide treatment in a murine model of coxsackievirus B3 myocarditis2025Nicolas Kelm, Meike Kespohl, Gintare Smagurauskaite, Serena Vales, Kalimuthu Karuppanan, Philomena Mburu, Arne Thiele, Sandra Pinkert, Thomas Bukur, Michael Mülleder, Nikolaus Berndt, karin Klingel, Matthias M. Gaida, Shoumo Bhattacharya, Antje BelingInstitue of Biochemistry, Charité, Universitätsmedizine Berlin, Corporate Member of Freie Universität Berlin and Humboldt - Universität zu Berlin, 10117, Berlin, Germany

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PARP inhibitors affect the replisome and replication fork progression during a single Sphase.2025Lina-Marie Briu, Chrystelle Maric, Nicolas Valentin, Nocolas Panara, Guillaume Chevreux, Giuseppe Baldacci, Jean-Charles CadoretUniversité Paris Cité, CNRS, Institut Jacques Monod, 15 rue Héléne Brion, F-75013 Paris, France

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Implications of tissue specific STING protein flux and abundance on inflammation and the development of targeted therapeutics2025Thomas E. Angel, Zhuo Chen, Ahmed Moghieb, Sze-Ling Ng, Allison M. Beal, Carol Capriotti, Leonard Azzarano, Debra Comroe, Michael Adam, Patrick Moore, Bao Hoang, Kelly Blough, Joanne Kuziw, Joshi M. Ramanjulu, G. Scott PesirdisResearch and Development, GlaxoSmithKline, Collegeville, Pennsylvania, United States of America

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Proof-of-concept study: A cost-efficient and scalable plasma proteomics pipeline utilizing the Evotip Pure subjected to more than 1,100 patient samples2025Pia H Jensen, Camilla O. Kyhl, Frederik Tolberg, Stoyan Stoychev, Joel Vej-Nielsen, Nicolai Bache, Dorte B. Bekker-Jensen, Michael Lund NielsenEvosep Biosystems

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Enhancing tandem MS sensitivity and peptide identification via ion pre-accumulation in an Orbitrap mass spectrometer2025Florian Harking, Ulises H. Guzman, Julia Kraegenbring, Hamish Stewart, Konstantin Aizikov, Heiner Koch, Kyle L. Fort, Alexander Harder, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

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Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates2025Cristina Moreno-Mariscal, Gisela Carrera-Alvarado, Leticia Mora, Fidel ToldráInstituto de Agroquímica y Tecnología de Alimentos (CSIC), Avenue Agustín Escardino 7, Paterna, Valencia, Spain

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Validation of Antibodies Suitable forFlow Cytometric Analysis andImmunopeptidomics of Peptide-MHCComplexes in the Outbred Swiss AlbinoMouse Strain2025Shanzou Chung, Isambard G. Knox-Johnson, Sarah E. Gazzard, Rungiu Song, Ngoc H. Le, Luise A. Cullen-McEwen, John F. Bertram, Anthony W. Purcell, Asolina BraunDepartment of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC Australia

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Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes affirms markers of disease2025Robert Moulder, M. Karoliina Hirvonen, Tommi Välikangas, Tomi Suomi, Lut Overbergh, Mark Peakman, Søren Brunak, Chantal Mathieu, Mikael Knip, Laura L. Elo, Riitta LahasmaaINNODIA Consortium

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Proteomic characterisation of three independent series of sequential cystic fibrosis strains in an international Pseudomonas aeruginosa reference panel indicates positive selection in late infection strains2025Joanna Drabinska, Lucia O' Connor, Caoilin McClean, Siobhán McCleanSchool of Biomolecular and Biomedical Science and UCD Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland

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Machine Learning-Enhanced Extraction of Protein Signatures of Renal Cell Carcinoma from Proteomics Data2025Hongyi Liu, Zhuo Ma, T. Mamie Lih, Lijun Chen, Yingwei Hu, Yuefan Wang, Zhenyu Sun, Yuanyu Huang, Yuanwei Xu, Hui ZhangDepartment of Pathology, John Hopkins University, MD 21231, USA, Krieger school of Arts and Sciences, John Hopkins University, MD 21218, USA

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Human Lung Alveolar Model with an Autologous Innate and Adaptive Immune Compartment2025Linda Steinacher, Bruno Gjeta, marisa Pimentel Mendes, Floriana Cremasco, Irineja Cubela, Marina Bellavista, Laura Gaspa Toneu, Luisa Lauer, Qianhui Yu, Ryo Okuda, Barzin Y. Nabet, Valimir Gayevskiy, Michel Sigel, Axel Ducret, Evodie Lassalle, Giacomo LazInstitute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center Basel, Switzerland

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Embryo-Induced Changes in the Protein Profile of Bovine Oviductal Extracellular Vesicles2025Rosane Mazzarella, José María Sánchez, Beatriz Fernandes-Fuertes, Sandra Guisado Egido, Michael McDonald, Alberto Álvarez-Barrientos, Esperanza González, Juan Manuel Falcón-Perez, Mikel Azkargorta, Felix Elortza, Maria Encina González, Pat Lonergan, DimitDepartment of Animal Reproduction, INIA-CSIC, Madrid, Spain

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Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production2025Carmen Figueras-Novoa, Masato Akutsu, Daichi Murata, Anne Weston, Ming Jiang, Beatriz Montaner, Christelle Dubois, Avinash Shenoy, Rupert BealeCell Biologogy of Infection Laboratory, The Francis Crick Institute, London, UK, Buchmann Institute for Molecular Life Sciences, Institute of Biochemistry IIGoethe University Max von Laue-Str. 15, Franfurt, 60438, Germany

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The basic helix-loop-helix transcription factor TCF4 recruits the Mediator Complex to activate gonadal genes and drive ovarian development2025O'Neil EV, Dupont SM, Capel BDepartment of Cell Biology, Duke University School of Medicine, Durham NC 27710

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Sensory nerve-secreted factors regulate basal keratinocyte function in vitro2025Avika Srivastava, Alexandra Noble, Samantha L. PayneDepartment of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Ontario, Canada, N1G2W1

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Genetic architecture of the red blood cell proteome in genetically diverse mice reveals central role of hemoglobin beta cysteine redox status in maintaining circulating glutathione pools2025Gregory R. Keele, Monika Dzieciatkowska, Ariel M. Hay, Matthew Vincent, Callan O'Connor, Daniel Stephenson, Julie A. Reisz, Travis Nemkov, Kirk C. Hansen, Grier P. Page, James C. Zimring, Gary A. Churchill, Angelo D' AlessandroRTI International, Research Triangle Park, NC, USA, Department of Biochemistry and Molecular Genetics, University of Colorado Denver- Anschutz Medical Campus, Aurora, CO, USA

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Fit for purpose high-throughput absolute quantitation of chimeric aducanumab in mouse cortex and plasma2025Emma H. Doud, Kathryn A. Haynes, Diogo Francisco Silva Santos, Amber L. Mosley, Sara K. Quinney, Stacey J. Sukoff Rizzo, Paul R. TerritoIndiana University School of Medicine, Indianaplois, IN, USA

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Tree-based quantification infers proteoform regulation in bottom-up proteomics data2025Constantin Ammar, Marvin Thielert, Caroline A. M. Weiss, Edwin H. Rodriguez, Maximilian T. Strauss, Florian A. Rosenberger, Wen-Feng Zeng, Matthias MannDepartment of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany

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Detection of Interleukin-19-like protein and its role in immune regulation strengthens Galleria mellonella as a model for host-pathogen interactions2025Anna Wronska, Agata Kaczmarek, Justyna Sobich, Mieczyslawa BogusMuseum and Institute of Zoology Polish Academy of Sciences

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Discovery of the antifungal compound ilicicolin K through genetic activation of the ilicicolin biosynthetic pathway in Trichoderma reesei2025Isabella Burger, Matthias Schmal, Kathrin Peikert, Lukas Fourtis, Christoph Suster, Christian Stanetty, Dominik Schnalzer, Barbara Hufnagel, Thomas Böttcher, Ruth Birner-Gruenberger, Robert L. Mach, Astrid R. Mach-Aigner, Matthias Schittmayer, Christian ZInstitute of Chemical, Enviromental and Bioscience Engineering, TU Wien, 1060, Vienna, Austria

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Rapid Proteomic Amelogenin Sex Estimation of Human and Cattle Remains Using Untargeted Evosep-timsTOF Mass Spectrometry2025Charllotte Blacka, Adam Dowle, Mik Lisowski, Michelle Alexander, Jessica Hendy, Kirsty Penkman, Jackie MoselyDepartment of Archaeology, University of York, York, UK

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Acid-responsive aggregated carrot-derived nanoantioxidants alleviate oxidative stress and restore osteoblast activity2025Jiao Peng, Rongyan Liu, Junyi Xu, Yingjuan Yao, Beibei Li, Dengke Chen, Zhuangpeng Chang, Rui Zhao, Yanlin feng, Ruigang Hou, Min Lee, Xiao ZhangSecond Clinical Medical College, School of Pharmacy and Key Laboratory of Cellular Physiology, Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China,

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Multiomics Identi es Potential Molecular Pro les Associated With Outcomes After BRAF-Targeted Therapy in Patients With BRAF V600E-Mutated Advanced Solid Tumors2025Martina Eriksen, Anne M. Hansen, Annelaura B. Nielsen, Filip Mundt, Matthias Mann, Ulrik Lassen, Lise B. Ahlborn, Martin Højgaard, Iben Spanggaard, Camilla Qvortrup, Christina W. Yde, Kristoffer S. RohrbergFaculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DK,

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Overcoming preservation challenges to enable single-cell proteomics of fixed cell and tissue samples with retained proteome integrity2025Agata N. Makar, Jocelyn Holkham, Sergio Lilla, Simon Wilkinson, Alex von KriegsheimCancer Research, UK, Scotland Centre, Insitute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XR, United Kingdom

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Organoid-based modeling of platinum resistance identifies KRT17 as both a response mediator and biomarker for targeted therapy in ovarian cancer2025Juliane Reichenbach, Juliana Schmid, Sophia Hierlmayer, Tingyu Zhang, Ilaria Piga, Sophia Geweniger, Jonas Fischer, Aarushi, Nemanja Vasovic, Anca Chelariu-Raicu, Fabian Kraus, Alexander Burges, Bastian Czogalla, Doris Mayr, Tobias Straub, Christoph KleinDepartment of Obstetrics and Gynecology, University Hospital, Ludwig-Maximillians University Munich, Munich, Germany

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Using a cost-efficient and scalable plasma proteomics pipeline to analyze more than 1,100 patient samples2025Evosep BiosystemsEvosep Biosystems

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Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell carcinoma2025Iordanis Ourailidis, Fabian Stögbauer, Yuxiang Zhou, Susanne Beck, Eva Romanovsky, Stephan Eckert, Barbara Wollenberg, Markus Wirth, Katja Steiger, Bernhard Kuster, Olivier Gires, Albrecht Stenzinger, Peter Schirmacher, Wilko Weichert, Peer-Hendrik Kuhn,Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

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AAV-mediated ARSA replacement for the treatment of Metachromatic Leukodystrophy2025Shyam Ramachandran, Jeffery Ardinger, Jie Bu, MiAngela Ramos, Lilu Guo, Dhiman Ghosh, Mahmud Hossain, Shih-Ching Chou, Yao Chen, Erik Wischhof, Swathi Ayloo, Roger Trullo, Yuxia Lou, Jessica Hogestyn, Daniel DuBreuil, Emiliy Crosier, Johanna Adams, Amy RiGenomic Medicine Unit, SANOFI, Waltham, MA

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Uridine-sensitized screening identifies genes and metabolic regulators of nucleotide synthesis2025Abigail Strefeler, Zakery N. Baker, Sylvain Chollet, Rachel M. Guerra, Julijana Ivanisevic, Hector Gallart-Ayala, David J. Pagliarini, Alexis A. JourdainDepartment of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, USA

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Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies2025Dmyto Morderer, Melissa C. Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil, Nora Pobitzer, Michelle R. Salemi, Brett S. Phinney, Goujun Bu, Na Zhao, Dennis W. Dickson, Melissa E. Murray, Wilfried RossolDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

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Single-Cell Proteomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes2025Jongmin Woo, Michael Loycano, Md Amanullah, Jiang Qian, Sarah Amend, Kenneth Pienta, Hui ZhangDepartment of Urology, James Buchanan Brady Urological Insitute, John Hopkins University School of Medicine, Baltimore, MD 21231, ,

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Chikusetsusaponin IVa targeted YAP as an inhibitor to attenuate liver fibrosis and hepatic stellate cell activation2025Kai Gao, Wei Zhang, Dong Xu, Meina Zhao, Xingru Tao, Yunyang Lu, Jingwen WangDepartment of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China

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A new class of type VI secretion system effectors can carry two toxic domains and are recognized through the WHIX motif for export2025Chaya Mushka Fridman, Kinga Keppel, Vladislav Rudenko, Jon Altuna-Alaverez, David Albesa-Jové, Erran Bosis, Dor SalomonDepartment of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel

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Plasma proteomics in von Willebrand disease and hemophilia A patients highlights VWF as main determinant of response to DDAVP treatment2025Jessica del Castillo Alferez, Eva R. Smit, Alexander B. Meijer, Karin Fijnvandraat, Marieke J. H. A. Kruip, Tirsa T. van Duijl, Maartje van den BiggelaarDepartment of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

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Deep spatial proteomics of ovarian cancer precursor lesions delineates early disease changes and cell-of-origin signatures2025Anuar Makhmut, Mihnea P. Dragomir, Sonja Fritzsche, Markus Moebs, Wolfgang D. Schmitt, Eliane T. Taube, Fabian CosciaCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Pathology, Berlin, Germany

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Pupylation-Based Proximity Labeling Unravels a Comprehensive Protein and Phosphoprotein Interactome of the Arabidopsis TOR Complex2025Shuai Zheng, Leonard Blaschek, Delphine Pottier, Luuk Robin Hoegen Dijkhof, Beyza Özmen, Peng Ken Lim, Qiao Wen Tan, Marek Mutwil, Alexander Sebastian Hauser, Staffan PerssonCopenhagen Plant Science Center (CPSC), Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, 1871 Denmark,

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Whey Protein Enzymatic Breakdown: Synthesis, Analysis, and Discovery of New Biologically Active Peptides in Papain-Derived Hydrolysates2025Michal Czelej, Katarzyna Garbacz, Tomasz Czernecki, Kamila Rachwal, Jacek awrzykowski, Adam WaskoDepartment of Biotechnology, Microbiology and Human Nutrition, Faculty of Food Science and Biotechnology, University of Life Sciences in Lublin, Skromna 8, 20-704 Lublin, Poland

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A simplified perchloric acid workflow with neutralization (PCA-N) for democratizing deep plasma proteomics at population scale2025Vincent Albrecht, Johannes B. Müller-Reif, Vincenth Brennsteiner, Matthias MannDepartment for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried

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Puerarin Ameliorates Sarcopenia in Aged Mice via Modulation of Inflammation and Oxidative Stress: Insights from Proteomics and Transcriptomics2025Shangjin Lin, Ying Cheng, Tao Cui, Fengjian Yang, Shenwu Yang, Yongqian FanDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China

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Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex2025Isaak Decoene, Hanna Svitina, Mohammed Belal Hamed, Anastassios Economou, Steve Stegen, Frank P. Luyten, Ioannis PapantoniouSkeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, O&N1, Herestraat 49, box 813, 3000, Leuven, Belgium

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The transepithelial transport of peptides derived from insects (Galleria mellonella and Alphitobius diaperinus) through static in vitro digestion (INFOGEST) and their ability to mitigating oxidative stress2025Zidan Ma, Martin Mondor, Christine Boesch, Oscar Abel Sánchez-Velázquez, Adam A. Dowle, Alan Javier Hernández-ÁlvarezFood Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK

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The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat2025Sofia Cusotto, Anna V. Golubeva, Alvaro Lopez Gallardo, Thomaz F. S. Bastiaanssen, Alexander V. Zhdanov, Gerad M. Moloney, Caitriona Scaife, Jane A. English, Susan A. Joyce, Timothy G. Dinan, John F. CryanAPC Microbiome Ireland, University College Cork, Cork, Ireland

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ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling2025Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne-Claude Gingras, Jasmin Lalonde, Nina JonesDepartment of Molecular and Cellular Biology, University of Guelph, Canada

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Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures2025Carlo Scialó, Weijia Zhong, Somanath Jagannath, Giuseppe Legname, Pietro Fratta, Magdalini Polymenidou, Oscar Wilkins, Davide Caredio, Marian Hruska-Plochan, Flavio Lurati, Martina Peter, Elena De Cecco, Luigi Celauro, Adriano AguzziDepartment of Quantiative Biomedicine, University of Zurich, Zurich, Switzerland

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Fresh insights into sex-specific mobility in Copper Age Perdigões (Reguengos de Monsaraz, Portugal) provided by amelogenin peptide analysis2025Marta Cintas-Peña, Lucy Shaw Evangelista, Antonio C. Valera, Leonardo García Sanjuán, Katharina Rebay-Salisbury, Claire Koenig, Jesper V. Olsen, Fabian KanzUniversidad de Sevilla, Seville, Spain

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Integrative network pharmacology, transcriptomics, and proteomics reveal the material basis and mechanism of the Shen Qing Weichang Formula against gastric cancer2025Yi Wang, Xiaoyu Sun, Mingming Ren, Fangqi Ma, Ruohan Zhao, Xiaohong Zhu, Yan Xu, Nida Cao, Yuanyuan Chen, Yongfu Pan, Aiguang ZhaoDepartment of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, South Wanping Rd. 725, Shanghai, 200032, China

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Parasite and vector circadian clocks mediate efficient malaria transmission2025Inés Bento, Brianna A. Parrington, Rushlenne Pascual, Alexander S. Goldberg, Eileen Wang, Hani Liu, Helene Borrmann, Mira Zelle, Nicholas Coburn, Joseph S. Takahashi, Joshua E. Elias, Maria M. Mota, Filipa Rijo-FerreiraBerkeley Public Health, Molecular and Cell Biology Department, University of California Berkeley, Berkeley, CA, USA

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Investigation of new autoantibodies in urothelial bladder cancer for biomarker discovery using immunoproteomics2025Samira Tabaei, Mohammadrasul Zareinejad, Mohammed Reza Haghshenas, Nasser Shakhssalim, Kambiz Gilany, Allan Stensballe, Abbas GhaderiShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments2025Kevin Eloff, Konstantinos Kalogeropoulos, Amandla Mabona, Oliver Morell, Rachel Catzel, Esperanza Rivera de Torre, Jakob Berg Jespersen, Wesley Williams, Sam P. B. van Beljouw, Marcin J. Skwark, Andreas Hougaard Laustsen, Stan J. J. Brouns, Anne Ljungars,InstaDeep Ltd, London, UK- Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark

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Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections2025Aditya Shekhar, Raffaella Di Lucrezia, Karoline Jerye, Vadim S. Korotkov, Kirsten Harmrolfs, Katharina Rox, Herbert A. Weich, Ishan Ghai, Florent Delhommel, Isabelle Becher, Carsten Degenhart, Eyad Fansa, Anke Unger, Peter Habenberger, Bert Klebl, Peer LuCompound Profiling and Screening, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany

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Casein kinase 1δ-regulated formation of GVBs induces resilience to tau pathology-mediated protein synthesis impairment2025Jasper F. M. Smits, Thijmen W. Ligthart, Marta Jorge-Olivia, Skip Middelhoff, Fleur Schipper, Renee Garritsen, Débora Pita-Illobre, Ka Wan Li, Wiep ScheperDepartment of Human Genetics, Amsterdam UMC - Vrije Universiteit Amsterdam, The Netherlands

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A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory gene expression2025Margaret R. Gaggioli, Angela G. Jones, Ionna Panagi, Erica J. Washington, Rachel E. Loney, Janina H. Muench, Matthew W. Foster, Richard G. Brennan, Teresa L. M. Thurston, Dennis C. KoDepartment of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA

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Confident PTM site localization of immunoaffinity-enriched peptides from cell lysates using electron activated dissociation (EAD)2025Mukesh Kumar, Greg Roman, Matthew D. Stone, Lei Xiong, Patrick Pribil, Remco van Soest, Kristina Jurcic, Sean A. Beausoleil, Matthew P. Stokes, Jeffrey C. SilvaCell Signaling Technology, USA: SCIEX, USA, Canada

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Menstrual blood serum extracellular vesicles reveal novel molecular biomarkers and potential endotypes of unexplained infertility2025Kieran Brennan, Raminta Vaiciuleviciute, Ilona Uzieliene, Jolita Pachaleva, Zaneta Kasilovskiene, Lina Piesiniene, Eiva Bernotiene, Margaret M. McGeeSchool of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland

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Proximity interactome of alphavirus replicase component nsP3 includes proviral host factors eIF4G and AHNAK2025Aditya Thiruvaiyaru, Sari Mattila, Mohammadreza Sadeghi, Krystyna Naumenko, Andres Merits, Markku, Varjosalo, Tero AholaDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland

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Optimization of Sequential Enzymatic Hydrolysis in Porcine Blood and the Influence on Peptide Profile and Bioactivity of Prepared Hydrolysates2025Cristina Moreno-Mariscal, Federico Moroni, Jaume Pérez-Sánchez, Leticia Mora, Fidel ToldráInstituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Avenue Agustín Escardino 7, 46980 Paterna, Spain

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SFRP1 upregulation causes hippocampal synaptic dysfunction and memory impairment2025Guadalupe Pereyra, María Inés Mateo, Pablo Miaja, María Jesús Martin-Bermejo, Marcos Martinez-Banos, Remco Klaassen, Agnés Gruart, Javier Rueda-Carrasco, Alba Fernández-Rodrigo, Esperenza López-Merino, Pilar Esteve, José A. Esteban, August B- Smit, José MCentro de Biología Molecular Severo Ochoa, CSIC-UAM, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain

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Comprehensive interrogation of synthetic lethality in the DNA damage response2025John Fielden, Sebastian M. Siegner, Danielle N. Gallagher, Markus S. Schröder, Maria Rosaria Dello Stritto, Simon Lam, Lena Kobel, Moritz F. Schlapansky, Stephen P. Jackson, Petr Cejka, Marco Jost, Jacob E. CornInstitute of Molecular Health Sciences, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Zurich, Switzerland

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Protocol to identify proteins as regulators of gene expression noise2025Oscar García-Blay, Maike M. K. HansenInstitute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, the Netherlands

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Single cell spatial proteomics maps human liver zonation patterns and their vulnerability to fibrosis2025Caroline A. M. Weiss, Lauryn A. Brown, Lucas Miranda, Paolo Pellizzoni, Shani Ben-Moshe, Sophia Steigerwald, Kirsten Remmert, Jonathan Hernandez, Karsten Borgwardt, Florian A. Rosenberger, Natalie Porat-Shliom, Matthias MannProteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND82025Ying Yang, Zhiheng Li, Yang Yang, Peifang Xiao, Zhixu He, Zimu Zhang, Yizhen Li, Lei Shi, Xiadong Wang, Yanfang Tao, Junjie Fan, Fenli Zhang, Chunxia Yang, Fahua Yao, Tongting Ji, Yongping Zhang, Bi Zhou, Juanjuan Yu, Ailian Gou, Zhongling Wei, Wanyan JiaInstitute of Pediatric Research, Children’s Hospital of Soochow University, No. 92 Zhongnan Street, SIP, Suzhou, 215003, China

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Blood proteome profiling for biomarker discovery in broilers with necrotic enteritis2025Svitlana Tretiak, Teresa Mendes Maia, Delphi Van Haver, An Staes, Simon Devos, Tom Rijsselaere, Evy Goossens, Filip Van, Immerseel, Francis Impens, Gunther AntonissenVIB-UGent Center for Medical Biotechnology, VIB, Ghent, B-9052, Belgium

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Exploring Proteomic and Metabolomic Interactions in a Yeast Consortium Designed to Enhance Bioactive Compounds in Wine Fermentations2025Andrés Planells-Cácel, Guillermo Quintas, Judit Pardo, Estefani Garcia-Rios, José Manuel GuillamónFood Biotechnology Department, Instituto de Agroquímica y Tecnología de Alimentos (IATA), Consejo Superior de Investigaciones Científicas (CSIC), Paterna, Valencia, Spain

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Establishment of minimum protein standards for Mycobacterium tuberculosis-derived extracellular vesicles through comparison of EV enrichment methods2025Joan M. Ryan, Kimberly Shelton, Monika Dzieciatkowska, Nicole Kruh-Garcia, Karen M. DobosDepartment of Microbiology, Immunology, and Pathology, Colorado State University, 2025 Campus Delivery, Fort Collins, CO, USA

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Proteomic Insights into Human Limbal Epithelial Progenitor-Derived Small Extracellular Vesicles2025Moritz Vincent Braunsperger, Gottfried Martin, Tabea Herzig, Isabell Kussberger, Andreas Giessl, Stefan Steimle, Ursula Schlötzer-Schrehardt, Günther Schlunck, Thomas Reinhard, Naresh PolisettiEye Center, Medical Center - Faculty of Medicine, University of Freiburg, Killianstrasse 5, 79106, Freiburg, Germany

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Effects of life-long hyperlipidaemia on age-dependent development of endothelial dysfunction in humanised dyslipidaemic mice2025Anna Bar, Piotr Berkowicz, Anna Kurpinska, Tasnim Mohaissen, Agnieszka Karas, Patrycja Kaczara, Joanna Suraj-Prazmowska, Magdalena Sternak, Brygida Marczyk, Agata Malinowska, Agnieszka Kij, Agnieszka Jasztal, Izabela Czyzynska-Cichon, Elsbet J. Pieterman,Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30-348, Krakow, Poland

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Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID2025Suman Shrestha, Matthew ER Maitland, Laili Jing, Shili Duan, David Y. Nie, Jonathan St-Germain, Dalia Barsyte-Lovejoy, Cheryl H. Arrowsmith, Brian RaughtPrincess Margaret Cancer Centre, University Health Network, Toronto, ON Canada

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Hybrid bioinks for embedded bioprinting of an artery model2025Uxue Aizarna-Lopetegui, Ada Herrero-Ruiz, Monize Caiado Decarli, Karla Chavarri, Lorenzo Moroni, Malou Henriksen-Lacey, Dorleta Jimenez de AberasturiCIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain

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Deep Visual Proteomics maps proteotoxicity in a genetic liver disease2025Florian A. Rosenberger, Sophia C. Madler, Katrine Holtz Thorhauge, Sophia Steigerwald, Malin Fromme, Mikhail Lebedev, Caroline A. M. Weiss, Marc Oeller, Maria Wahle, Andreas Metousis, Maximilian Zwiebel, Niklas A. Schmacke, Sönke Detlefsen, Peter Boor, OnDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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SysQuan: repurposing SILAC mice for the cost-effective absolute quantitation of the human proteome2025Yassene Mohammed, Vincent R. Richard, M. Immanuel Reyes Madlangsakay, Ying Lao, Victor Spicer, Robert Popp, Claudia Gaither, Laura Hennecken, Wolfgnag Kleinekofort, René P. Zahedi, Christoph H. BochersSegal Cancer Proteomics Centre, Jewish General Hospital, Montreal, QC, Canada, Manitoba Centre for Proteomics and Systems Biology, Winnipeg, MB, Canada

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A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis2025Olijnik, Zoë C. Wong, Christina Simglou Karali, Korsuk Sirinukunwattana, Hosuk Ryou, Ruggiero Norfo, Qian Cheng, Joana Carrelha, Zermin Ren, Supat Thongjuea, Vijay A. Rathinam, Anandi Krishan, Daniel Royston, Gabriel A. Rabinovich, Adam J. Mead, Bethan PsBiomedical Research Centre Hematology Theme; University of Oxford; Oxford, OX3 9DS, UK.

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Quantitative proteomics and phosphoproteomics analysis of patient-derived ovarian cancer stem cells2025Giulia Franciosa, Valentina Nieddu, Chiara Battistini, Miriam Caffarini, Michela Lupia, Nicoletta Colombo, Nicola Fusco, Jesper V. Olsen, Ugo CavallaroUnit of Gynecological Oncology Research, European Institute of Oncology IRCSS, Milano, Italy

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Calcineurin controls the cytokinesis machinery during thermal stress in Cryptococcus deneoforman2025Vikas Yadav, Anna Floyd Averette, Rajendra Upadhya, Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA

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Inhibition of Tyrosinase and Melanogenesis by Carboxylic Acids: Mechanistic Insights and Safety Evaluation2025Yu-Pei Chen, Mingyu Li, Zirong Liu, Jinxiong Wu, Fangfang Chen, Shudi ZhangThe School of Public Health, Fujian Medical University, Fuzhou 350122, China

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Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function2025Elin L. Strachan, Eugene T. Dillon, Mairéad Sullivan, Jeffrey C, Glennon, Amandine Peyrel, Jérome Sarniguet, Kevin Dubois, Benjamin Delprat, Breandán N. Kennedy, Niamh C. O'SullivanUCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland

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Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness2025Nordin D. Zandhuis, Antonia Bradaric, Carmen van der Zwaan, Arie J. Hoogendijk, Branka Popovic, Monika C. WolkersDepartment of Research, T Cell Differentiation Lab, Sanquin Blood Supply Foundation, Amsterdam, The Netherlands

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Cysteine Reactivity Profiling Illuminates Monoclonal Antibody Disulfide Bond Reduction Mechanisms in Biopharmaceutical Process Intermediates2025Taku Tsukidate, Zhenshu Wang, Andrew Hsieh, Patricia Rose, Xuanwen LiAnalytical Research and Development Mass Spectrometry, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States

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The Validation of Antibodies Suitable for Flow Cytometric Analysis and Immunopeptidomics of Peptide–MHC Complexes in the Outbred Swiss Albino Mouse Strain2025Shanzou Chung, Isambard G. Knox-Johnson, Sarah E. Gazzard, Runqiu Song, Ngoc H. Le, Luise A. Cullen-McEwen, John F. Bertram, Anthony W. Purcell, Asolina BraunDepartment of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia

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Proteomics of colorectal tumors identifies the role of CAVIN1 in tumor relapse2025Ana Martinez-Val, Leander Van der Hoeven, Dorte B. Bekker-Jensen, Margarita Melnikova Jørgensen, Jesper Nors, Giulia Franciosa, Claus L. Andersen, Jesper B. Bramsen, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Large-scale proteomic analysis of glioblastoma tissues reveals novel molecular insights and potential therapeutic targets2025Juanjuan Wang, Simone Maarup, Vincent Fougner, Annelaura B. Nielsen, Ulrik Lassen, Luca Robinson, Frederik O. Bagger, Dorte S. NoeroexeCopenhagen University Hospital, Copenhagen, Denmark

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Cell type resolved spatial proteomics defines the transition of precancerous fallopian tube lesions to invasive ovarian cancer2025Andreas Metousis, Hilary Kenny, Lisa Schweizer, Agnes Bilecz, Rahul Krishnan, Isabel AlcazarMax Planck Institute of Biochemistry, Munich, Germany

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Identification of pivotal genes and regulatory networks associated with SAH based on multi-omics analysis and machine learning2025Haoran Lu, Teng Xie, Xiaohong Qin, Shanshan Wei, Zilong Zhao, Xizhi Liu, Liquan Wu, Rui Ding, Zhibiao ChenDepartment of Neurosurgery, Renmin Hospital of Wuhan University, 238 Jiefang Street, Whuhan, 430060, Hubei, China

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The molecular signature of heat stress in sweat reveals non-invasive biomarker candidates for health monitoring2025Noé Brasier, Carmela Niederberger, Martina Zanella, Alaa Othman, Ralph Schlapbach, Laura Kunz, Antje Dittmann, Kelly Reeve. Michael Prummer, Jörg GoldhahnInstitute of Translational Medicine, Department Health Science and Technology, ETH Zurich, Zurich, Switzerland

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Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken2025Svitlana Tretiak, Teresa Mendes Maia, Tom Rijsselaere, Filip Van Immerseel, Richard Ducatelle, Francis Impens, Gunther AntonissenPharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Livestock Gut Health Team (LiGHT) Ghent, Ghent University, 9820, Merelbreke, Belgium

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Multiplexed Deep Visual Proteomics Unveils Spatial Heterogeneity and Rare Endocrine States in Human Adult Pancreatic Islets2025Frederic Ballllosera Navarro, Anna Martinez Casals, Ferenc Kovacs, Jocelyn E. Manning Fox, Peter Horvath, Patrick E. MacDonald, Matthias Mann, Emma LundbergDepartment of Bioengineering, Stanford University, Stanford, CA, USA

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Characterizing Changes in the Serum Proteome During Circadian Rhythm Utilizing the Evosep One and a Data Independent Strategy2025Matthew E. Daly, Matt Spick, Cristopher J. Hughes, Scarlet Ferrinho, Cheryl M. Isherwood, Lee A. Gethings, Hana Hassanin, Daan R. van der Veen, Debra J. Skene, Jonathan D. JohnstonWaters Corporation, USA

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Mass spectrometry-based quantification of proteins and post-translational modifications in dried blood: longitudinal sampling of patients with sepsis in Tanzania2025Matthew W. Foster, Timothy J. McMahon, James S. Ngocho, Asia H. Kipengele, Marlene Violette, Youwei Chen, Deng B. Madut, Robert S. Plumb, A. Ian Wong, Lingye Chen, Grace M. Lee, Philoteus A. Sakasaka, Blandina T. Mmbaga, John A. Crump, Micah T. McClain, CDepartment of Medicine, Duke Proteomics and Metabolomics Core Facility, Duke University School of Medicine, Durham NC USA

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Label-free quantitation of proteins and peptides using ZT Scan DIA2025Patrick Pribil, Mohammadreza Dorvash, Anthony Purcell, Ihor BatruchSCIEX Canada, SCIEX USA, Monash University, Australia

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Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus2025Cristopher T. A. Lewis, Roger Moreno-Justicia, Lola Savoure, Enrique Calvo, Agata Bak, Jenni Laitila, Robert A. E. Seaborne, Steen Larsen, Hiroyuki Iwamoto, Marina Cefis, Jose A. Morais, Gilles Gouspillou, Jorge Alegre-Cebollada, Thomas J. Hawke, Jesús VaDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark

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NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging2025Sabina Chubanava, Iulia Karavaeva, Amy M. Ehrlich, Roger M. Justicia, Astrid L. Basse, Ivan Kulik, Emilie Balbram, Danial Ahwazi, Samuel R. Heaselgrave, Kajetan Trost, Ben Stocks, Ondrej Hodek, Raissa N. Rodrigues, Jesper F. Havelund, Farina L. Schlabs, SNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Cophenhagen, Denmark

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Wolbachia infection confers post-translational modification of glutamic acid decarboxylase and other proteins in D. melanogaster2025Sarah M. Boothman, Sarah Preston, Jonathan MindenDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, Pennsylvania, USA

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Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring2025Yeanqi Jin, Jinbin Liu, Xueli Zhang, Liang Zhang, Ying Cui, Xiaoyang, Haoxian Zhu, Zhifan Chen, Mengya Liu, Xiyu Wu, Xinyu Chen, Shuoxin Liao, Guanrong Wu, Xiang Fang, Qianli MengDepartment of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

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Whole-exome tumor-agnostic ctDNA analysis enhances minimal residual disease detection and reveals relapse mechanisms in localized colon cancer2025Jorge Martin-Arana, Francisco Gimeno-Valiente, Tenna Vesterman Henriksen, Blanca García-Micó, Belén Martínez-Castedo, Valentina Gambardella, Carolina Martínez-Ciapaglini, Brenda Palomar, Marisol Huerta, Daniel G. Camblor, Miguel García Bartolomé, Juan AntDepartment of Medical Oncology, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain

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Transcriptomic and Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 82025Yanfei Ji, Dandan Xu, Wenxuan Si, Yu Zhang, Muhammad Zahoor Khan, Xia Zhao, Wenqiang LiuDepartment of Veterinary Medicine, School of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China

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Characterization of Extracellular Vesicles Derived From Human Precision‐Cut Liver Slices in Metabolic Dysfunction‐Associated Steatotic Liver Disease2025Yana Geng, Ke Lou, Janine Stam, Dorenda Oosterhuis, Alan R. Gorter, Marius ven den Heuvel, Rossella Crescitelli, Vincent E. de Meijer, Justina C. Wolters, Peter OlingaDepartment of Pharmaceutical Technology and Biopharmacy, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands

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Proteomic and Metabolomic Analysis of the Neuroprotective Effects of Lycium Ruthenicum Polyphenols in Diabetic Peripheral Neuropathy Mice2025Qi Tian, Hongdou Cao, Liwen Chu, Hua Gao, Qinghan GaoSchool of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China

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Vascular dysfunction in Huntington’s disease is located at the blood-CSF barrier and is rescued by sphingosine-1-phosphate receptor agonist2025Krzysztof Kucharz, Rana Soylu-Kucharz, Martine Saint-Pierre, Melanie Alpaugh, Filippa L. Qvist, Maria Björkqvist, Niels Henning Skotte, Francesca Cicchetti, Martin LauritzenDepartment of Neuroscience, University of Copenhagen, Cophenhagen, Denmark

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Identification of putative baroreceptors in human aortic arch by histological and omics analyses2025Yankey Yundung, Jaroslav Pelisek, Umberto Maccio, Zsuzsanna Varga, Houria Ech-Cherif, Enni Markkanen, Fabian Rössler, Ahmed Ouda, Omer Dzemali, Alexander Zimmermann, Benedikt ReutersbergDepartment of Vascular Surgery, University Hospital Zurich, Zurich, Switzerland

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Direct relationship between protein expression and progeny yield of herpes simplex virus 12025Moeka Nobe, Yuhei Maruzuru, Kosuke Takeshima, Fumio Maeda, Hideo Kusano, Raiki Yoshimura, Takara Nishiyama, Hyeongki Park, Yoshitaka Kozaki, Shingo Iwami, Naoto Koyanagi, Akihisa Kato, Tohuru Natsume, Shungo Adachi, Yasushi KawaguchiDivison of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP302025Andreas Damianou, Hannah B. L. Jones, Athina Grigoriou, Mohammed A. Akbor, Edward Jenkins, Phillip D. Charles, Iolanda Vendrell, Simon Davis, Benedikt M. KesslerTarget Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, OX3 7FZ Oxford, UK

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Pre-Analytical Drivers of Bias in Bead-Enriched Plasma Proteomics2025Kathrin Korff, Johannes B. Mueller-Reif, Dorothea Fichtl, Vincent Albrecht, Alcia-Sophie Schebesta, Ericka C. M. Itang, Sebastian Virreira Winter, Lesca M. Holdt, Daniel Teupser, Matthias Mann, Philipp E. GeyerDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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Automated MagNet Enrichment Unlocks Deep and Cost-Effective LC-MS Plasma Proteomics2025Erkka Järvinen, Xiaonan Liu, Markku,´Varjosalo, Salla KeskitaloInstitute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki, Findland, ,

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100-spd 30-spd 60-spdtimstof-pro-2
Annexin A2 Contributes to Release of Extracellular Vimentin in Response to Inflammation2025Zhiyao Yuan, Z. Ostrowska-Podhorodecka, T. Cox, M. Norouzi, Y. Wang, K. Robaszkiewicz, M. Siatkowska, K. Xia, A. Ali, M. Abovsky, I. Jurisica, P. Smith, C. A. McCullochNanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, China

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Glyoxal is a superior fixative to formaldehyde in promoting antigenicity and structural integrity in murine cardiac tissues2025Allen C.T. Teng, Dev Mehangrey, Ava Vandenbelt, Karl Vearncombe, Justin D. Callahan, Priya Mistry, Wenping Li, Cristine J. Reitz, Omar Hamed, Madison Roche, Uros Kusmanov, Jason E. Fish, Slava Epelman, Anthony O. GramoliniTranslational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Canada

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RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion2025Fiona H. Murphy, Adlin Abramian, Remco V. Klaassen, Frank Koopmans, Claudia M. Persoon, August B. Smit, Ruud F. Toonen, Matthijs VerhageDepartment of Human Genetics, Center for Neurogenomics and Cognitive Research (CNCR), Amsterdam University Medical Center (UMC), Amsterdam, Netherlands

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Proteomic analysis of nasopharyngeal aspirate biomarkers for prematurity-related bronchopulmonary dysplasia2025"Fernando Garrido-Muñoz, Alejandro Fernández-Vega, Rebeca GregorioHernández, Marta Padín-Fontán, Mónica de las Heras-Martín, Marta Teresa-Palacio, Paula Alonso-Quintela, Alberto Trujillo-Fagundo, Alba Pérez-Pérez, Marcelino Pumarada-PrietoPerinatal Brain Damage Group. Biomedical Research and Innovation Institute of Cadiz (INiBICA). Puerta del Mar University Hospital, Cadiz, Spain

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Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions2025Katarzyna Tutak, Izabela Broniarek, Andrzej Zielezinski, Daria Niewiadomska, Tomasz Skrzypczak, Anna Baud, Krzysztof SobczakDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 6, Poland

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A combined experimental and computational analysis of mantATP turnover in skinned muscle fibers2025Mauro Montesel, Cosimo De Napoli, Luisa Schmidt, Elena Germinario, Ulises H. Guzmanc, Jesper V. Olsenc, Lorenzo Marcuccia, Leonardo NogaraaDepartment of Biomedical Sciences, University of Padua, Padua 35131, Italy

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Relevance of transportome among the mechanisms of chemoresistance in hepatoblastoma2025Candela Cives-Losada, Maitane Asensio, Oscar Briz, Luis Miguel Chinchilla-Tábora, María Manuela Barranco, Álvaro del Río-Álvarez, Maria Luz Martinez-Chantar, Matias A. Avila, Stefano Cairo, Carolina Armengol, Jose J.G. Marin, Rocio I.R. MaciasExperimental Hepatology and Drug Targeting (HEVEPHARM), Institute for Biomedical Research of Salamanca (IBSAL), University of Salamanca, 37007 Salamanca, Spain

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Structural switch in acetylcholine receptors in developing muscle2025Huanhuan Li, Jinfeng Teng, Ryan E HibbsDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA

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Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism2025Marcos Zamora-Dorta, Sara Laine-Menéndez, David Abia, Pliar González-García, Luis C. López, Paula Fernández-Montes, Enrique Calvo, Jesús Vázquez, José Antonio Enríquez, Eduardo BalsaDepartment de Biología Molecular and Centro de Biología Molecular Severo Ochoa (UAM-CSIC) Madrid, Spain

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Phosphoproteomics Reveals L1CAM-Associated Signaling Networks in High-Grade Serous Ovarian Carcinoma: Implications for Radioresistance and Tumorigenesis2025Tihomir Zh Todorov, Ricardo Coelho, Francis Jacob, Viola Heinzelmann-Schwarz, Roger Schibli, Martin Béhé, Jürgen Grünberg, Michal GrzmilCenter for Radiopharmaceutical Sciences, PSI Center for Life Sciences, 5232 Viligen PSI, Switzerland

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SARS-CoV-2 damages cardiomyocyte mitochondria and implicates long COVID-associated cardiovascular manifestations2025Wenliang Che, Shuai Guo, Yanqun Wang, Xiaohua Wan, Bingyu Tan, Hailing Li, Jiasuer Alifu, Mengyun Zhu, Zesong Chen, Peiyao Li, Lei Zhang, Zhaoyong Zhang, Yiliang Wang, Xiaohan Huang, Xinsheng Wang, Jian Zhu, Xijang Pan, Fa Zhang, Peiyi Wang, Sen-Fang Sui,Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China

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A foundational neuronal protein network model unifying multimodal genetic, transcriptional, and proteomic perturbations in schizophrenia2025Greta Pintacuda, Yu-Han H. Hsu, Petra Páleníková, Ugne Dubonyte, Nadine Fornelos, Miao Chen, Daya Mena, Julia C. Biagini, Travis Botts, Makayla Martorana, Danzel Rebelo, Joshua K. T. Ching, Ethan Crouse, Hilena Gebre, Xian Adiconis, Nathan Haywood, Sean SStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA

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Quantitative proteomics of pediatric adrenocortical tumors reveals a continuum of molecular alterations and identifies prognostically relevant subgroups2025Andreas Metousis, Victoria Fincke, Stefan Wudy, Joern Pons-Kuehnemann, Marina Kunstreich, Eva Jüttner, Pascal Johann, Antje Redlich, Lisa Schweizer, Matthias Mann, Rainer Claus, Michaela KuhlenMax Planck Institute of Biochemistry, Planegg, Germany

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60-spdthermo-orbitrap-astral
Comprehensive Comparison of Methods for Isolation of Extracellular Vesicles from Human Plasma2025Patil Shivprasad Suresh, Qibin ZhangCenter for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina 28081, United States

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Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development2025Borzo Gharibi, Oliver C. K. Inge, Irene Rodriguez-Hernandez, Paul C. Driscoll, Christelle Dubois, Ming Jiang, Michael Howell, J. Mark Skehel, James I. Macrae, Silvia D. M. SantosQuantitative Stem Cell Biology Laboratory, The Francis Crick Institute, London NW 1AT, UK

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Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes2025Narainrit Karuna, Claire Tonry, Mark Ledwidge, Nadezhda Glezeva, Joe Gallagher, Ken McDonald, Chris J. WatsonWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK

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Immunolocalization and proteomic analyses of IZUMO1 in porcine spermatozoa2025Miranda Hernández-Falcó, Paula Sáez-Espinosa, Laura Robles-Gómez, Francisco Alberto García-Vázquez, Maria José Izquierdo-Rico, Pedro José Llamas-LópezDepartment of Biotechnology, University of Alicante, Alicante, Spain

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Protein kinase C eta enhances Golgi-localized signaling and is associated with Alzheimer’s disease using a recessive mode of inheritance2025Maria Celeste Gauron, Dmitry Prokopenko, Sanghun Lee, Sarah A. Wolfe, Julian Hecker, Julian Willet, Mohammad Waqas, Gema Lordén, Yimin Yang, Joshua E. Mayfield, Isabel Castanho, Kristina Mullin, Sarah Morgan, Georg Hahn, Dawn L. Demeo, Winston Hide, LarsDepartment of Pharmacology, University of California; San Diego, La Jolla, CA, USA

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Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis2025Adam N. Trautwig, Edward J. Fox, Eric B. Dammer, Anantharaman Shantaraman, Lingyan Ping, Duc M. Duong, Caroline M. Watson, Fang Wu, Seneshaw Asress, Qi Guo, Allan I. Levey, James J. Lah, Federico Verde, Alberto Doretti, Antonia Ratti, Nocola Ticozzi, CindDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA, USA

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Integrating antigen capturing nanoparticles and type 1 conventional dendritic cell therapy for in situ cancer immunization2025Chih-Jia Chao, Endong Zhang, Duong N. Trinh, Edidiong Udofa, Hanchen Lin, Caylee Silvers, Jiawei Huo, Shan He, Jingtian Zheng, Xiaoying Cai, Qing Bao, Luyu Zhang, Philana Phan, Sara M. Elgrndy, Xiangqian Shi, Joanna E. Burdette, Steve Seung-Young Lee, YuDepartment of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL, USA

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Postbiotic Parabacteroides Distasonis Supplementation Enhances Intestinal and Skeletal Muscle Function in Aged Mice2025Pablo Morgado-Cáceres, Hernán Huerta, Christian Bergman, Reinaldo Figueroa, Paula Farias, Gabriel Quiroz, Ute Woehlbier, Karen Mella, Osmán Díaz-Rivera, Sergio Linsambarth, Paulina Calderón-Romero, Felipe A. Court, Denisse Sepulveda, Daniela Sauma, PatricCenter for Intergrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile

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A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma2025Eimear Lagan, Dáire Gannon, Ademar Jesus Silva, Peter Bibawi, Anthony M. Doherty, Darragh Nimmo, Rachel McCole, Craig Monger, Giovani Luiz Genesi, Aurelie Vanderlinden, james A. Innes, Charlotte L. E. Jones, Lu Yang, Bryan Chen, Guido van Mierlo, Pascal WSmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland

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Trauma Induces Intravascular Hemolysis, Exacerbated by RBC Transfusion and Associated with Disrupted Arginine-Nitric Oxide Metabolism2024Ernest E. Moore, Angela Sauaia, Monika Dzieciatkowska, William Hallas, Otto Thielen, Margot DeBot, Alexis Cralley, Ian LaCroix, Christopher Erickson, Sanchayita Mitra, Anirban Banerjee, Kenneth Jones, and Kirk C. HansenUniversity of Colorado Denver, School of Medicine, Department of Biochemistry and Molecular Genetics, Aurora, CO

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Calcium carbonate polymorph selection in fish otoliths: A key role of phosphorylation of Starmaker-like protein2024Marta Kalka, Klaudia Bielak, Maciej Ptak, Jarosław Stolarski, Piotr Dobryszycki, Magdalena WojtasWroclaw University of Science and Technology, Faculty of Chemistry, Department of Biochemistry, Molecular Biology and Biotechnology, Wrocław, Poland

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Single cell proteomics by mass spectrometry reveals deep epigenetic insight and new targets of a class specific histone deacetylase inhibitor2024Benjamin C. OrsburnThe Department of Pharmacology and Molecular Sciences, the Johns Hopkins University School of Medicine, Baltimore, MD, USA, , , , ,

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100-spd 200-spd 30-spd 300-spd 500-spd 60-spdbruker-timstof-scp
Direct translation of incoming retroviral genomes2024Julia Köppke, Luise-Elektra Keller, Michelle Stuck, Nicolas D. Arnow, Norbert Bannert, Joerg Doellinger & Oya CingözRobert Koch Institute, Department of Infectious Diseases, Unit of Sexually Transmitted Bacterial Pathogens and HIV, Berlin, Germany

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FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy2024Vera A. van der Weijden, Maximilian Stötzel, Dhanur P. Iyer, Beatrix Fauler, Elzbieta Gralinska, Mohammed Shahraz, David Meierhofer, Martin Vingron, Steffen Rulands, Theodore Alexandrov, Thorsten Mielke & Aydan Bulut-KarsliogluStem Cell Chromatin Group, Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany

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whisper-40spdthermo-q-exactive-hf
Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions2024Andrés Trávez, Carmen Tercero-Alcázar, Alejandro Correa-Sáez, María Jesús González-Rellán, Oriol A. Rangel-Zúñiga, Amaia Rodríguez, Antonio Membrives, Gema Frühbeck, Rubén Nogueiras, Marco A. Calzado, Rocío Guzmán-Ruiz & María M. MalagónDepartment of Cell Biology, Physiology, and Immunology, Maimonides Institute for Biomedical Research of Córdoba (IMIBIC), University of Córdoba (UCO), Reina Sofía University Hospital (HURS), Córdoba, Spain

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Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome2024Cristina Lorca, María Fernández-Rhodes, Jose Antonio Sánchez Milán, María Mulet, Félix Elortza, Alfredo Ramos-Miguel, Luis F. Callado, J. Javier Meana, Maria Mur, Iolanda Batalla, Elisabet Vilella, Aida Serra and Xavier Gallart-PalauBiomedical Research Institute of Lleida Dr. Pifarré Foundation (IRBLLEIDA), Neuroscience Area, +Pec Proteomics Research Group (+PPRG), University Hospital Arnau de Vilanova,Lleida, Spain

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Multi-omics profiling with untargeted proteomics for blood-based early detection of lung cancer2024Madhuvanthi Ramaiah, Saividya Ramaswamy, Purva Ranjan, Guanhua Shu, Peter Spiro, Benjamin Ta, Dijana Vitko, Jacob Waiss, Zachary Yanagihara, Robert Zawada, Jimmy Yi Zeng, Susan Zhang, James Yee, John E. Blume, Chinmay Belthangady, Bruce Wilcox, Philip MaPrognomiQ, Inc., San Mateo, CA, USA

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Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis2024Sophia Steigerwald, Ankit Sinha, Kyle L. Fort, Wen-Feng Zeng, Lili Niu, Christoph Wichmann, Arne Kreutzmann, Daniel Mourad, Konstantin Aizikov, Dmitry Grinfeld, Alexander Makarov, Matthias Mann, Florian MeierDepartment Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany, ,

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100-spd 200-spd 60-spdthermo-orbitrap-exploris-480
Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients2024Marc Vervuurt, Joseph M. Schrader, Anna M. de Kort, Iris Kersten, Hans J. C. T. Wessels, Catharina J. M. Klijn, Floris H. B. M. Schreuder, H. Bea Kuiperij, Jolein Gloerich, William E. Van Nostrand & Marcel M. VerbeekDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, 830 TML, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands

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Kinase inhibitor pulldown assay (KiP) for clinical proteomics2024Lester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USALester and Sue Smith Breast Center and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA

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timsTOF HT Improves Protein Identification and Quantitative Reproducibility for Deep Unbiased Plasma Protein Biomarker Discovery2024Chinmay Belthangady, John Blume, Jessica K. Chan, Guillermo Flores-Campuzano, Yuntao Hu, Manway Liu, Mark A. Marispini, Megan G. Mora, Saividya Ramaswamy, Purva Ranjan, Preston B. Williams, Robert J. X. Zawada, Philip Ma, and Bruce E. WilcoxPrognomiQ Inc., San Mateo, California, United States, , ,

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100-spd 30-spd 60-spdbruker-timstof-ht timstof-pro-2
Proteomics of colorectal tumors identifies the role of CAVIN1 in tumor formation and progression2024Jesper Olsen, Ana Martinez-Val, Leander van der Hoeven, Dorte Bekker-Jensen, Margarita Jørgensen, Jesper Nors, Giulia Franciosa, Claus Andersen, Jesper BramsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

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60-spdthermo-orbitrap-exploris-480
The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum2024Bradley S. Jones, Daniel D. Hu, Kathleen R. Nicholson, Rachel M. Cronin, Matthew M. Champion, and Patricia A. ChampionDepartment of Biological Sciences, Eck Institute for Global Health, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana

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Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis2024Fredrik Leo, Rolf Lood, Kristina A. Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes WickströmDepartment of Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden

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The CDK Pho85 inhibits Whi7 Start repressor to promote cell cycle entry in budding yeast2024Cristina Ros-Carrero, Mihai Spiridon-Bodi, J Carlos Igual and Mercè Gomar-AlbaInstitut de Biotecnologia i Biomedicina (BIOTECMED) and Departament de Bioquímica i Biologia Molecula rUniversitat de València, Burjassot Spain

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Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications2024Claudia Ctortecka, Natalie M. Clark, Brian Boyle, Anjali Seth, D. R. Mani, Namrata D. Udeshi & Steven A. CarrBroad Institute of MIT and Harvard, Cambridge, MA, USA

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The Molecular Twin artificial-intelligence platform integrates multi-omic data to predict outcomes for pancreatic adenocarcinoma patients2024Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R. Ferrone, Lei Zheng, Jason H. Moore, Warren Tourtellotte, Jennifer E. Van Eyk & Dan TheodorescuSamuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

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thermo-orbitrap-exploris-480
Mechanism of chaperone coordination during cotranslational protein folding in bacteria2024Alžběta Roeselová, Sarah L. Maslen, Santosh Shivakumaraswamy, Grant A. Pellowe, Steven Howell, Dhira Joshi, Joanna Redmond, Svend Kjaer, J. Mark Skehel and David BalchinProtein Biogenesis Laboratory, The Francis Crick Institute, London, UK

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30-spdthermo-orbitrap-fusion-lumos
Plasma Proteomic Analysis Based on 4D-DIA Evaluates the Clinical Response to Imrecoxib in the Early Treatment of Osteoarthritis2024López-Gómez J, Villareal L, Andrés M, Ponte I, Xicoy B, Zamora L, Vilaseca M, Roque ABiochemistry and Molecular Biology Department, Biosciences Faculty. Universitat Autònoma de Barcelona, Spain,

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Proteomic Biomarkers for the Prediction of Transition to Psychosis in Individuals at Clinical High Risk: A Multi-cohort Model Development Study2024Carrie E Bearden, Kristin S Cadenhead, Jean Addington, Elaine F Walker, Tyrone D Cannon, Mary Cannon, Pat McGorry, Paul Amminger, Gerard Cagney, Barnaby Nelson, Clark Jeffries, Diana Perkins, David R CotterDepartment of Psychiatry, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin, Ireland

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timstof-pro
Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis2024Cory M. Willis, Luca Peruzzotti-Jametti, Valentina Fossati, Frank Edenhofer, Tommaso Leonardi, Christian Frezza, Irina Mohorianu, Angelo D’Alessandro, and Stefano PluchinoDepartment of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK

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Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms2024Kieran Wynne, Carrie E. Bearden, Scott W. Woods, Barbara Cornblatt, Daniel Mathalon, William Stone, Tyrone D. Cannon, Jean Addington, Kristin S. Cadenhead, Diana Perkins, Clark Jeffries, David CotterDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland

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A macroevolution-inspired approach to reveal novel antibiotic resistance mechanisms2024Luiz Pedro de Carvalho, Fernanda Subtil, Teresa Machado, Holly Douglas, Joanna Kirkpatrick, Mark Skehel & Acely Garza-GarciaThe Herbert Wertheim UF Scripps Institute, FL, United States

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thermo-orbitrap-fusion-lumos
Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis2024Shuai Zheng, Ouda Khammy, Lise Charlotte Marie Noack, Andreas De Meyer, Ghazanfar Abbas Khan, Nancy De Winne, Dominique Eeckhout, Daniel van Damme, Staffan PerssonCopenhagen Plant Science Center, Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark

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30-spdtimstof-pro
The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 sub-strates in Mycobacterium marinum2024Bradley S. Jones, Daniel D. Hu, Kathleen R. Nicholson, Rachel M. Cronin, Matthew M. Champion and Patricia A. ChampionDepartment of Biological Sciences, Eck Institute for Global Health, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, United States

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Activity-Guided Proteomic Profiling of Proteasomes Uncovers a Variety of Active (And Inactive) Proteasome Species2024Manisha Priyadarsini Sahoo, Tali Lavy, Noam Cohen, Indrajit Sahu & Oded KleifeldFaculty of Biology, Technion-Israel Institute of Technology, Technion City, Haifa, Israel,

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The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells2024Min Qiao, Carmen Van der Zwaan, Maria Giustina Rotordam,Thomas John, Laura Hertz, Arjan J. Hoogendijk, Nadine Becker, Christian Wagner, Marieke Von Lindern, Stephane Egee, Emile Van den Akker and Lars KaestnerTheoretical Medicine and Biosciences, Campus University Hospital, Saarland University, Homburg, Germany

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Homo sapiens reached the higher latitudes of Europe by 45,000 years ago2024Michael Hein, Sahra Talamo, Lukas Wacker, Harald Meller, Holger Dietl, Jörg Orschiedt, Jesper V. Olsen, Hugo Zeberg, Kay Prüfer, Johannes Krause, Matthias Meyer, Frido Welker, Shannon P. McPherron, Tim Schüler & Jean-Jacques HublinMax Planck Institute for Evolutionary Anthropology, Leipzig, Germany

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200-spdthermo-orbitrap-exploris-480
Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue2024Rune Daucke, Charlotte V. Rift, Nicolai S. Bager, Kartikey Saxena, Peter R. Koffeldt, Jakob Woessmann, Valdemaras Petrosius, Eric Santoni-Rugiu, Bjarne W. kristensen, Pia Klausen & Erwin M. SchoofDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark

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whisper-20spdthermo-orbitrap-eclipse-tribid
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition2024Amelia C. Peterson, Florian Harking, Ole Østergaard, Rasmus Rydbirk, Susana Aznar, Hamish Stewart, Yue Xuan, Daniel Hermanson, Stevan Horning, Christian Hock, Alexander Makarov, Vlad Zabrouskov & Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark,

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30-spdthermo-orbitrap-astral thermo-orbitrap-exploris-480
Proximity labeling proteomics reveals Kv1.3 potassium channel immune interactors in microglia2024Christine A. Bowen, Hai M. Nguyen, Young Lin, Pritha Bagchi, Aditya Natu, Claudia Espinosa-Garcia, Erica Werner, Prateek Kumar, Brendan R. Tobin, Levi Wood, Victor Faundez, Heike Wulff, Nicholas T. Seyfried, Srikant RangarajuCenter for Neurodegenerative Diseases, Emory University, Atlanta, GA, USA,

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15-spd 30-spdthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF2024Charlotte Adams, Wassim Gabriel, Kris Laukens, Mario Picciani, Mathias Wilhelm, Wout Bittremieux, Kurt BoonenDepartment of Computer Science, University of Antwerp, Antwerp, Belgium

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100-spdtimstof-pro
Phosphoproteomic investigation of targets of protein phosphatases in EGFR signaling2024Akihiro Eguchi, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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60-spdthermo-orbitrap-exploris-480
STREAMLINED PROTEOME-WIDE IDENTIFICATION OF DRUG TARGETS INDICATES ORGAN-SPECIFIC ENGAGEMENT2024Tanveer Singh Batth, Marie Locard-Paulet, Nadezhda T. Doncheva, Blanca Lopez Mendez, Lars Juhl Jensen, and Jesper Velgaard OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

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30-spdthermo-orbitrap-exploris-480
Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes2024Jeppe Kjærgaard Larsen, Ben Stocks, John Henderson, Daniel Andersson, Jesper Bäckdah, Daniel Eriksson-Hogling, Jacob V. Stidsen, Kei Sakamoto, Kurt Højlund, Mikael Rydén, Juleen R. Zierath, Anna Krook, Atul S. DeshmukhNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

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30-spdtimstof-pro-2
DYRKP kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression2024Minjae Kim, Gabriel Lemes Jorge, Moritz Aschern, Stéphan Cuiné, Marie Bertrand,Malika Mekhalfi, Jae-Seong Yang, Jay J. Thelen, Fred Beisson, Gilles Peltier, and Yonghua Li-BeissonCEA, CNRS, Aix-Marseille University, Institute of Biosciences and Biotechnologies of Aix9 Marseille (BIAM),Saint-Paul-lez-Durance, France

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timstof-pro-2
Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems2024Ana Blanco-Doval, Mikel Azkargorta, Ibon Iloro, Jabier Beaskoetxea, Felix Elortza, Luis Javier R. Barron, Noelia AldaiLactiker Research Group, Department of Pharmacy and Food Sciences, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Spain

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30-spdtimstof-pro
Targeting cancer-derived extracellular vesicles by combining CD147 inhibition with tissue factor pathway inhibitor for the management of urothelial cancer cells2024Vijay Kumar Boddu, Piet Zamzow, Mario Wolfgang Kramer, Axel S. Merseburger, Sivahari Prasad Gorantla, Matthias Klinger, Lena Cramer, Thorben Sauer, Timo Gemoll, Nikolas von Bubnoff, Frank Gieseler & Masoud DarabiDepartment of Hematology and Oncology, Section for Experimental Oncology, University Hospital Schleswig-Holstein, Lübeck, Germany,

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15-spd extended-method
PU.1 Eviction at Lymphocyte-Specific Chromatin Domains Mediates Glucocorticoid Response in Acute Lymphoblastic Leukemia2024Yizhou Huang, Han Zhao, Xiaolu Tai, Wenqian Xu, Hansen Kosasih, David Kealy, Katherine Bridge, Weiye Zhao, Andrew Holding, Adam Dowle, Samuel Taylor, Gaoxian Song, Diego Fajardo, Yashna Walia, Meng Wang, Chao Zhang, Jin Wang, Jian-Qing MiState Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai

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100-spdbruker-timstof-ht
The Proteome of Extracellular Vesicles Released from Pulmonary Microvascular Endothelium Reveals Impact of Oxygen Conditions on Biotrauma2024Wolfgang Schaubmayr, Beatrix Hochreiter, Eva Hunyadi-Gulyas, Louise Riegler, Katy Schmidt, Akos Tiboldi, Bernhard Moses, Klaus U. Klein, Katharina Krenn, Gisela Scharbert, Thomas Mohr, Johannes A. Schmid, Andreas Spittler,and Verena TretterDepartment of Anesthesia, General Intensive Care and Pain Medicine, Medical University of Vienna, Austria

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15-spdthermo-orbitrap-fusion-lumos
Automated high-throughput biological sex identification from archaeological human dental enamel using targeted proteomics2024Palesa P. Madupe, Gaudry B. Troché, Nuno Vibe Hermann, Marina Martínez de Pinillos, María MartinónTorres, Sandra Mularczyk, Marie Louise Schjellerup Jørkov, Christopher Gerner,Fabian Kanz, Ana Martinez-Val1, Enrico Cappellini, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty ofHealth and Medical Sciences, University of Copenhagen, Denmark.,

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200-spd 30-spdthermo-orbitrap-exploris-480
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons2024Linda Makhlouf, Joshua J. Peter, Helge M. Magnussen, Rohan Thakur, David Millrine, Thomas C. Minshull, Grace Harrison, Joby Varghese, Frederic Lamoliatte, Martina Foglizzo, Thomas Macartney, Antonio N. Calabrese, Elton Zeqiraj & Yogesh KulathuMRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, UK

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30-spdthermo-orbitrap-eclipse-tribid
SARS-CoV-2 Infection and Anemia—A Focus on RBC Deformability and Membrane Proteomics—Integrated Observational Prospective Study2024Angelo D’Alessandro, Elena Krisnevskaya, Valentina Leguizamon,Ines Hernández, Carolina de la Torre, Joan-Josep Bech, Josep-Tomàs Navarro and Joan-Lluis Vives-CorronsMedical Campus, University of Colorado Anschutz, Aurora, USA

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diaPASEF Enables High-throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development2024Taku Tsukidate, Alyssa Q. Stiving, Shannon Rivera, Ansuman Sahoo, Sri Madabhushi, Xuanwen LiAnalytical Research & Development Mass Spectrometry, New Jersey, United States, ,

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100-spd 15-spd 30-spdtimstof-pro-2
Polydopamine nanoparticles as a non-pharmaceutical tool in the treatment of fatty liver disease2024Alessio Carmignani, Matteo Battaglini, Martina Bartolucci, Andrea Petretto, Mirko Prato, Gianni CiofaniIstituto Italiano di Tecnologia, Smart Bio-Interfaces, Pontedera, Italy

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30-spdthermo-orbitrap-exploris-480
TIMAHAC: Streamlined Tandem IMAC-HILIC Workflow for Simultaneous and High-Throughput Plant Phosphoproteomics and N-glycoproteomics2024Chin-Wen Chen, Pei-Yi Lin, Ying-Mi Lai, Miao-Hsia Lin, Shu-Yu Lin, ChuanChih HsuInstitution of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan

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30-spdbruker-timstof-ht
Phosphoproteomic Analysis and Organotypic Cultures for the Study of Signaling Pathways2024Zilu Ye, Hans H. Wandall, and Sally DabelsteenCopenhagen Center for Glycomics, Departments of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark

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thermo-orbitrap-exploris-480
Universal pretreatment development for low-input proteomics using lauryl maltose neopentyl glycol2024Ryo Konno, Masaki Ishikawa, Daisuke Nakajima, Yusuke Endo, Osamu Ohara, Yusuke KawashimaDepartment of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan

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whisper-80-spdthermo-orbitrap-exploris-480
Structure and interactions of the endogenous human Commander complex2024Saara Laulumaa, Esa-Pekka Kumpula, Juha T. Huiskonen & Markku VarjosaloInstitute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Finland

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60-spdtimstof-pro
Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates2024Tilman Werner, Agnes Schäfer, Michael Hennes, Miguel Cosenza Contreras, Guadalupe Espadas, Eduard Sabido, Lena Cook, Axel Pagenstecher, Niko Pinter, Tobias Feilen, Alexander Grote, Christopher Nimsky, Jörg Walter Bartsch, Oliver SchillingInstitute for Surgical Pathology, Faculty of Medicine, University Medical Center Freiburg

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30-spdthermo-orbitrap-fusion-lumos
Neat plasma proteomics: getting the best out of the worst2024Ines Metatla, Kevin Roger, Cerina Chhuon, Sara Ceccacci, Manuel Chapelle, Pierre-Olivier Schmit, Vadim Demichev & Ida Chiara GuerreraProteomics Platform Necker, Université Paris Cité-Structure Fédérative de Recherche Necker, Paris, France, ,

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100-spd 60-spd whisper-40spdtimstof-pro
AlphaPept: a modern and open framework for MS-based proteomic2024Maximilian T. Strauss, Isabell Bludau, Wen-Feng Zeng, Eugenia Voytik, Constantin Ammar, Julia P. Schessner, Rajesh Ilango, Michelle Gill, Florian Meier, Sander Willems & Matthias MannDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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200-spdtimstof-pro
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease2024Sephira Ryman, Maya Yutsis, Gayle K. Deutsch, Elizabeth Mormino, Alexandra Trelle, Anthony D. Wagner, Geoffrey A. Kerchner, Lu Tian, Carlos Cruchaga, Victor W. Henderson, Thomas J. Montine, Per Borghammer, Tony Wyss-Coray & Kathleen L. PostonDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA, USA

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timstof-pro
Personalized phosphoproteomics of skeletal muscle insulin resistance and exercise links MINDY1 to insulin action2024Johan D. Onslev, Alexis Diaz-Vegas, Magnus R. Leandersson, Jonas Møller Kristensen, Kohei Kido, Erik A. Richter, Kurt Højlund, Benjamin L. Parker, Kristen Cooke, Guang Yang, Christian Pehmøller, Sean J. Humphrey, David E. James, Jørgen F.P. WojtaszewskiCharles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, New South Wales, Australia

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30-spdthermo-orbitrap-exploris-480
Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation2024Javier G. Casado, Eva Pericuesta, Alfonso Gutiérrez-Adán, Esperanza González, Mikel Azkargorta, Ricardo Conde, Maider Bizkarguenaga, Nieves Embade, Félix Elortza, Juan M. Falcón-Pérez, Óscar Millet, Lauro González-Fernández, Beatriz Macías-GarcíaDepartamento de Medicina Animal, Facultad de Veterinaria, Grupo de Investigación Medicina Interna Veterinaria (MINVET), Instituto de Investigación INBIO G+C, Universidad de Extremadura, Cáceres, Spain

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30-spdtimstof-pro
Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production2024Moeka Nobe, Yuhei Maruzuru, Kosuke Takeshima, Fumio Maeda, Hideo Kusano, Raiki Yoshimura, Takara Nishiyama, Hyeongki Park, Yoshitaka Kozaki, Shingo Iwami, Naoto Koyanagi, Akihisa Kato1, Tohru Natsume, Shungo Adachi, and Yasushi KawaguchiDivision of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Japan

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100-spdthermo-q-exactive-hf-x
Human Dermal Decellularized ECM Hydrogels as Scaffolds for 3D In Vitro Skin aging Models2024Estibaliz Fernandez‐Carro, Ana Rosa Remacha, Irene Orera, Giuseppe Lattanzio, Alberto Garcia‐Barrios, Jesús del Barrio, Clara Alcaine and Jesús CirizaTissue Microenvironment (TME) Lab. Aragón Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain

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60-spdbruker-timstof-flex
Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy2024Aristeidis Panagiotou, Aurélie Richard, Angélique Amo, Yulianna Koziy, Souhila Medjkane, Sergio Valente, Rossella Fioravanti, Catherine Pioche-Durieu, Laurent Lignière, Guillaume Chevreux, Antonello Mai & Jonathan B. WeitzmanUniversité Paris Cité, CNRS, UMR7126 Epigenetics and Cell Fate, Paris, France

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30-spdthermo-orbitrap-fusion-lumos
Widespread S-persulfidation in activated macrophages as a protective mechanism against oxidative-inflammatory stress2024Talal Salti, Ilana Braunstein, Yael Haimovich, Tamar Ziv, Moran BenharDepartment of Biochemistry, Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel

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15-spdthermo-q-exactive-hf
Proteomic Analysis Reveals Trilaciclib-Induced Senescence2024Marina Hermosilla-Trespaderne, Mark Xinchen Hu-Yang, Abeer Dannoura, Andrew M. Frey, Amy L. George, Matthias Trost, José Luis Marín-RubioBiosciences Institute, Newcastle University, Newcastle-upon-Tyne, UK

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100-spdbruker-timstof-ht
Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations2024Eirini Tsirvouli, Ana Martinez del Val, Liv Thommesen, Astrid Lægreid, Martin Kuiper, Jesper Olsen, Åsmund FlobakDepartment of Biology, Norwegian University of Science and Technology, Trondheim, Norway

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60-spdthermo-orbitrap-exploris-480
Proteomic study of left ventricle and cortex in rats after myocardial infarction2024Mengli Chang, Huanhuan Wang, Yuxin Lei, Hongjun Yang, Jing Xu & Shihuan TangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China

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A T6SS in the coral pathogen Vibrio coralliilyticus secretes an arsenal of anti-eukaryotic effectors and contributes to virulence2024Shir Mass, Hadar Cohen, Motti Gerlic, Blake Ushijima, Julia C. van Kessel, Eran Bosis, and Dor SalomonDepartment of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Israel

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15-spdthermo-q-exactive-hf
Molecular interactions of human receptor tyrosine kinase oncogenic fusions2024Giovanna Dashi, Markku VarjosaloUniversity of Helsinki, Helsinki, Finland

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Integrating multiplex-staining and multiplex-DIA: Profiling the tumor microenvironment spatial proteome for precision cancer research2024Xiang Zheng, Andreas Mund, Matthias MannUniversity of Copenhagen, Copenhagen, Denmark

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A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series2024Travis Nemkov, Francesca Cendali, Monika Dzieciatkowska, Daniel Stephenson, Kirk C. Hansen, Catherine M. Jankowski, Angelo D’Alessandro and Ryan J. MarkerDepartment of Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, USA

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NFATC2IP is a mediator of SUMO- dependent genome integrity2024Tiffany Cho, Lisa Hoeg, Dheva Setiaputra, and Daniel DurocherLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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60-spdtimstof-pro-2
RNA damage compartmentalization by DHX9 stress granules2024Yilong Zhou, Amol Panhale, Maria Shvedunova, Mirela Balan, Alejandro Gomez-Auli, Herbert Holz, Janine Seyfferth, Martin Helmstädter, Séverine Kayser, Yuling Zhao, Niyazi Umut Erdogdu, Iga Grzadzielewska, Gerhard Mittler, Thomas Manke, and Asifa AkhtarMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

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30-spdthermo-orbitrap-exploris-480
DIP-MS: ultra-deep interaction proteomics for the deconvolution of protein complexes2024Fabian Frommelt, Andrea Fossati, Federico Uliana, Fabian Wendt, Peng Xue, Moritz Heusel, Bernd Wollscheid, Ruedi Aebersold, Rodolfo Ciuffa & Matthias GstaigerDepartment of Biology, Institute of Molecular Systems Biology, Zurich, Switzerland

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60-spdthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles2024George Haddad, Judith BlaineDivision of Renal Disease and Hypertension, Department of Medicine, School of Medicine, University of Colorado, Aurora, USA

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Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies2024Dmytro Morderer, Melissa C. Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil, Nora Pobitzer, Michelle Salemi, Brett S. Phinney, Dennis W. Dickson, Melissa E. Murray and Wilfried RossollDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

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100-spdtimstof-pro-2
Matrimeres are systemic nanoscale mediators of tissue integrity and function2024Koushik Debnath, Irfan Qayoom, Steven O’Donnell, Julia Ekiert, Can Wang, Mark A. Sanborn, Chang Liu, Ambar Rivera, Ik Sung Cho, Saiumamaheswari Saichellappa, Peter T. Toth, Dolly Mehta, Jalees Rehman, Xiaoping Du, Yu Gao, and Jae-Won ShinDepartment of Pharmacology and Regenerative Medicine, College of Medicine, Chicargo, IL, USA

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60-spdthermo-q-exactive-hf
Cheap, Robust and Versatile Two-Dimensional Chromatography system for Proteomics of Nanogram Scale Samples2024Eduardo S. Kitano, Gareth Nisbet, Yana Demyanenko, Katarzyna M Kowalczyk, Louisa Iselin, Stephen Cross, Alfredo Castello, Shabaz MohammedRosalind Franklin Institute, Harwell Campus, United Kingdom

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30-spdthermo-orbitrap-ascend-tribid
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication2024Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. CarltonOrganelle Dynamics Laboratory, The Francis Crick Institute, London, UK

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Extracellular vesicles derived CXCL4 is a candidate serum tumor biomarker for colorectal cancer2024Jinye Xie, Shan Xing, Hongbo Jiang, Jiaju Zhang, Daxiao Li, Shiqiong Niu, Zhijian Huang, and Haofan YinDepartment of Laboratory Medicine, Zhongshan City People’s Hospital, Zhongshan, Guangdong, China

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30-spdbruker-timstof-pro
Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies2024Jonah F. Byrne, Colm Healy, Melanie Föcking, Meike Heurich, Subash Raj Susai, David Mongan, Kieran Wynne, Eleftheria Kodosaki, Scott W. Woods, Barbara A. Cornblatt, William S. Stone, Daniel H. Mathalon, Carrie E. Bearden, Kristin S. Cadenhead, Jean AddingDepartment of Psychiatry, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin, Ireland

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timstof-pro
Exploring the role of production and release of proteins for microbial interactions in kombucha2024Jacqueline Rodriguez Rey, Thierry Tran, Amaury Aumeunier, Aurélie Rieu, François Verdier, Antoine Martin, Hervé Alexandre, Raphaëlle Tourdot-Maréchal, Cosette GrandvaletUMR PAM 1517, Université Bourgogne, Institut Agro, Dijon, France

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30-spdtimstof-pro-2
Enrichment, Characterization, and Proteomic Profiling of Small Extracellular Vesicles Derived from Human Limbal Mesenchymal Stromal Cells and Melanocytes2024Sebastian Kistenmacher, Melanie Schwämmle, Gottfried Martin, Eva Ulrich, Stefan Tholen, Oliver Schilling, Andreas Gießl, Ursula Schlötzer-Schrehardt, Felicitas Bucher, Günther Schlunck, Irina Nazarenko, Thomas Reinhard and Naresh PolisettiEye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany

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30-spdbruker-timstof-flex
Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine Model2024Anna Faragó, Ágnes Zvara, László Tiszlavicz, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Zoltán Hegedűs, Enikő Szabó, Sára Eszter Surguta, József Tóvári, László G. Puskás, and Gábor J. SzebeniAstridbio Technologies Ltd., Wimmer Fülöp utca 1, Hungary

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15-spdthermo-orbitrap-fusion-lumos
Global organization of phenylpropanoid and anthocyanin pathways revealed by proximity labeling of trans-cinnamic acid 4-hydroxylase (CYP73A412) in Petunia inflata petal protoplasts2024Javiera Aravena-Calvo, Silas Busck-Mellor, Tomas LaursenDepartment of Plant and Environmental Sciences (PLEN), Section for Plant Biochemistry, University of Copenhagen, Denmark

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30-spdtimstof-pro-2
Craspase Orthologs Cleave a Nonconserved Site in Target Protein Csx302024Sam P. B. van Beljouw, Anna C. Haagsma, Konstantinos Kalogeropoulos, Martin Pabst, and Stan J. J. BrounsDepartment of Bionanoscience, Delft University of Technology, Delft, Netherlands

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whisper-20spdthermo-orbitrap-eclipse-tribid
Relaxation of mucosal fibronectin fibers in late gut inflammation following neutrophil infiltration in mice2024Ronja Rappold, Konstantinos Kalogeropoulus, Ulrich auf dem Keller, Emma Slack, Viola VogelETH Zürich, Switzerland

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whisper-20spdthermo-orbitrap-exploris-480
Craspase Orthologs Cleave a Nonconserved Site in Target Protein Csx302024Sam P. B. van Beljouw, Anna C. Haagsma, Konstantinos Kalogeropoulos, Martin Pabst, Stan J. J. BrounsDepartment of Bionanoscience, Delft University of Technology, Delft, Netherlands

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whisper-20spdthermo-orbitrap-eclipse-tribid
A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage2024James Barrett, Mihris I.S. Naduthodi, Yuwei Mao, Clément Dégut, Sabina Musiał, Aidan Salter, Mark C. Leake, Michael J. Plevin, Alistair J. McCormick, James N. Blaza, Luke C.M. MackinderDepartment of Biology, University of York, York, UK

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60-spdbruker-timstof-ht
The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing2024Matheus H Dias, Vladyslava Liudkovska, Jasmine Montenegro Navarro, Lisanne Giebel, Julien Champagne, Chrysa Papagianni, Onno B Bleijerveld, Arno Velds, Reuven Agami, René Bernards & Maciej CieślaDivision of Molecular Carcinogenesis and Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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extended-methodthermo-orbitrap-exploris-480
Increasing sustainability in palaeoproteomics by optimizing digestion times for large-scale archaeological bone analyses2024Louise Le Meillour, Virginie Sinet-Mathiot, Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Dorothea Mylopotamitaki, Gaudry Troché, Huan Xia, Jorsua Herrera Bethencourt, Karen Ruebens, Geoff M. Smith, Zandra Fagernäs, Frido WelkerUniversity of Copenhagen, Copenhagen, Denmark

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100-spdthermo-orbitrap-exploris-480
Theabrownin ameliorated lipid accumulation via modulating circadian rhythms in oleic acid-induced HepG2 cells2024Chunyan Zhao, Lei Zhao, Zelin Li, Yue Miao, Shuwen Lei, Bo Shan, Qiuping Wang, Chao Tan, Chunxiu Peng, Jiashun GongCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China

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thermo-orbitrap-exploris-480
Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids2024Chaitanya Dingare, Dominica Cao, Jenny Jingni Yang, Berna Sozen, Benjamin SteventonDeptartment of Genetics, University of Cambridge, Downing Site, Cambridge, UK,

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500-spdbruker-timstof-ht thermo-orbitrap-exploris-240
O-linked glycosylations in human milk casein and major whey proteins during lactation2024Martin Nørmark Thesbjerg, Katrine Overgaard Poulsen, Julie Astono, Nina Aagaard Poulsen, Lotte Bach Larsen, Søren Drud-Heydary Nielsen, Allan Stensballe, Ulrik Kræmer SundekildeDepartment of Food Science, Aarhus University, Agro Food Park 48, Aarhus N, Denmark

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60-spdtimstof-pro-2
Spatial Proteomics Reveals Alcohol-Induced Damages to the Crypts and Villi of the Mouse Small Intestine2024Patil Shivprasad Suresh, Xinguo Sun, Zhanxiang Zhou, and Qibin ZhangCenter for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, United States

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30-spdthermo-orbitrap-exploris-240
Characterization of a Chimeric Resilin-Elastin Structural Protein Dedicated to 3D Bioprinting as a Bioink Component2024Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chruścielewska, Katarzyna Kosowska, Natalia Łukasiewicz, Iwona Sokołowska, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła and Marta KlakFoundation of Research and Science Development, Warsaw, Poland

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thermo-orbitrap-exploris-480
Urinary Proteomics and Outcomes in Heart Failure With Preserved Ejection Fraction2024Yixin Wang, Peter H. Schafer, Sarah Hersey, Leonidas N. Carayannopoulos, Dietmar Seiffert, Ching‐Pin Chang, David A. Gordon, Francisco Ramirez‐Valle, Douglas L. Mann, Thomas P. Cappola and Julio A. ChirinosUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

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30-spdthermo-q-exactive-hf
Ribosomal composition affects the noncanonical translation and toxicity of polyglycine-containing proteins in fragile X-associated conditions2024Katarzyna Tutak, Izabela Broniarek, Andrzej Zielezinski, Daria Niewiadomska, Anna Baud, Krzysztof SobczakDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Poznan, Poland

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thermo-orbitrap-exploris-480
Optimization of protocols for blood-derived extracellular vesicles for studies in liver diseases2024Magnolia Martínez-Aguilar, María Camila Trillos-Almanza, Justina C. Wolters, Manon Buist-Homan, TransplantLines Investigators, Frederike van Vilsteren, Hans Blokzijl, Han MoshageDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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30-spdthermo-orbitrap-exploris-480
Reduced ATP turnover during hibernation in relaxed skeletal muscle2024Cosimo de Napoli, Luisa Schmidt, Mauro Montesel, Laura Cussonneau, Samuele Sanniti, Lorenzo Marcucci, Elena Germinario, Jonas Kindberg, Alina Evans, Guillemette Gauquelin-Koch, Fabrice Bertile, Etienne Lefai, Marcus krüger, Leonardo NogaraDepartment of Biomedical Science University of Padova, Italy

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60-spdtimstof-pro
Plasma/Serum Proteomics based on Mass Spectrometry2024Yiying ZhuDepartment of Chemistry, Tsinghua University, Beijing, China

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thermo-orbitrap-astral
The proteomic profile is altered but not repaired after bariatric surgery in type 2 diabetes pigs2024Karolina Ferenc, Michał Marcinkowski, Jarosław Olszewski, Paweł Kowalczyk, Tomaš Pilžys, Damian Garbicz, Naser Dib, Bianka Świderska, Piotr Matyba, Zdzisław Gajewski, Elżbieta Grzesiuk & Romuald ZabielskiCenter for Translational Medicine, Warsaw University of Life Sciences, Warsaw, Poland

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15-spdthermo-orbitrap-exploris-480
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant2024Sofia Kalaidopoulou Nteak, Franziska Völlmy, Marie V. Lukassen, Henk van den Toorn, Maurits A. den Boer, Albert Bondt, Sjors P. A. van der Lans, Pieter-Jan Haas, Arjan D. van Zuilen, Suzan H. M. Rooijakkers, and Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands

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30-spdthermo-orbitrap-exploris-480
Mass Spectrometry-Based Proteomics to Evaluate the Circulating Proteome in Idiopathic Pulmonary Fibrosis (IPF)2024A. A. Menon, H. Mulder, M. L. Neely, F. Meissner, B. Gansen, P. Papavasileiou, C. Hesslinger, M. L. Salisbury, B. D. Southern, T. B. Leonard, J. L. ToddMedical University of South Carolina, Charleston, SC, United States

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Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics2024Stephan Eckert, Nicola Berner, Karl Kramer, Annika Schneider, Julian Müller, Severin Lechner, Sarah Brajkovic, Amirhossein Sakhteman, Christian Graetz, Jonas Fackler, Michael Dudek, Michael W. Pfaffl, Percy Knolle, Stephanie Wilhelm & Bernhard KusterProteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, Freising, Germany

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thermo-orbitrap-eclipse-tribid
Machine learning strategies to tackle data challenges in mass spectrometry-based proteomics2024Ceder Dens, Charlotte Adams, Kris Laukens, Wout BittremieuxAdrem Data Lab, Department of Computer Science, University of Antwerp, Antwerpen, Belgium

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timstof-pro
Unraveling the proteome landscape of mouse hematopoietic stem and progenitor compartment with high sensitivity low-input proteomics2024Nil Üresin, Valdemaras Petrosius, Pedro Aragon-Fernandez, Benjamin Furtwängler, Erwin M. Schoof, & Bo T. PorseThe Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen,Copenhagen, Denmark.

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Comparative proteomic analysis of the ovarian fluid and eggs of Siberian sturgeon2024Natalia Kodzik, Andrzej Ciereszko, Bożena Szczepkowska, Agata Malinowska & Mariola Aleksandra DietrichDepartment of Gamete and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Poland

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15-spdthermo-orbitrap-exploris-480
Deep Visual Proteomics advances human colon organoid models by revealing a switch to an in vivo-like phenotype upon xenotransplantation2024Frederik Post, Annika Hausmann, Sonja Kabatnik, Sophia Steigerwald, Alexandra Brand, Ditte Lange Clement, Jonathan Skov, Theresa Louise Boye, Toshiro Sato, Casper Steenholdt, Andreas Mund, Ole Haagen Nielsen, Kim Bak Jensen, Matthias MannNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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whisper-40spdthermo-orbitrap-astral
FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells2024Luisa Weisbrod, Luigi Capriotti, Marco Hofmann, Valerie Spieler, Herbert Dersch, Bernd Voedisch, Peter Schmidt, Susanne KnakeRecombinant Protein Discovery, CSL Innovation GmbH, Marburg, Germany

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extended-methodthermo-orbitrap-exploris-240
The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base— reveals signicant changes in host cell protein expression and activation by multiple SARS-CoV-2 variants2024Sini Huuskonen, Xiaonan Liu, Taras Redchuk, Kari Salokas, Rickard Lundberg, Sari Maljanen, Milja Belik, Arttu Reinholm, Pekka Kolehmainen, Garima Tripathi, Pia Laine, Sergei Belanov, Petri Auvinen, Maria Vartiainen, Larissa LaineThe university of Helsinki, Helsinki, Finland

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60-spdtimstof-pro
Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis2024Mengjie Yang, Hong Jiang, Xinyu Ding, Lu Zhang, Huaying Zhang, Jiahao Chen, Lijun Li, Xinqin He, Zhixiong Huang & Qionghua ChenClinical Medical Research Center for Gynecological Reproductive Health of Fujian Province, Laboratory of Research and Diagnosis of Gynecological Diseases of Xiamen City, China

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15-spdtimstof-pro
Integrated proteogenomic analysis for inherited bone marrow failure syndrome2024Manabu Wakamatsu, Hideki Muramatsu, Hironori Sato, Masaki Ishikawa, Ryo Konno, Daisuke Nakajima, Motoharu Hamada, Yusuke Okuno, Yusuke Kawashima, Asahito Hama, Masafumi Ito, Hideto Iwafuchi, Yoshiyuki Takahashi & Osamu OharaDepartment of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan

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thermo-orbitrap-exploris-480
Evotip Pure brings innovative sample storage and introduction to high-sensitivity and scalable LC-MS workflows2024Evosep BiosystemsEvosep Biosystems

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Whisper Zoom drives scalable workflows for high-sensitivity applications through standardization and ease-of-use2024Evosep BiosystemsEvosep Biosystems, , ,

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whisper-zoom-120-spd whisper-zoom-20-spd whisper-zoom-40-spd whisper-zoom-80-spdtimstof-pro-2
Unlocking the plasma proteome with Evotip Pure based, standardized and scalable workflows2024Evosep BiosystemsEvosep Biosystems

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100-spdthermo-orbitrap-astral
Efficient proteomics with an automated sample preparation strategy leveraged by Evotip Pure and the AssayMAP Bravo2024Evosep BiosystemsEvosep Biosystems, , ,

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100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spdbruker-timstof-ht
Scalability for high-throughput proteomics – Evotip Pure integration with the Biomek i5 liquid handler2024Evosep BiosystemsEvosep Biosystems,

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200-spd 500-spdbruker-timstof-ht
A multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities2024Christian Panse, Karel Stejskal, Thibaut Douché, Bérangère Lombard, Andrea Schuhmann, Damarys Loew, Karl Mechtler, Mariette Matondo, Mandy Rettel, Dominic Helm, Francis Impens, Simon Devos, Anna Shevchenko, Paolo Nanni, Eduard SabidóCentre for Genomic Regulation, The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain,

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15-spd whisper-20spdthermo-q-exactive-hf
Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants2024Chao Yang, Abhijeet Pataskar, Xiaodong Feng, Celia R. Berkers, Onno B. Bleijerveld, Reuven AgamiDivision of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands

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extended-methodthermo-orbitrap-exploris-480
NPEPPS Is a Druggable Driver of Platinum Resistance2024Shahla Romal, Cailin Deiter, Tsung Wai Kan, Nathaniel Xander, Stephanie P. Araki, Molishree Joshi, Mahmood Javaid, Eric T. Clambey, Ryan Layer, Teemu D. Laajala, Sarah J. Parker, Tokameh Mahmoudi, Tahlita C.M. Zuiverloon, Dan Theodorescu, James C CostelloDepartment of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado

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thermo-orbitrap-fusion-lumos
The balance between antiviral and antibacterial responses during M. Tuberculosis infection is regulated by the ubiquitin ligase CBL2024Tina Truong, Kelsey Martin, Michelle Salemi, Abigail Ray, Brett S. Phinney, Bennett H. PennDepartment of Internal Medicine, University of California, Davis, Davis, California, United States of America, ,

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30-spd 60-spdbruker-timstof-ht timstof-pro-2
GLP-1-directed NMDA receptor antagonism for obesity treatment2024Luisa Sachs, Roger Moreno-Justicia, Rebecca Rohlfs, James C. Ford, Jonathan D. Douros, Brian Finan, Bryan Portillo, Kyle Grose, Jacob E. Petersen, Mette Trauelsen, Annette Feuchtinger, Richard D. DiMarchi, Thue W. Schwartz, Christoffer ClemmensenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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30-spdtimstof-pro-2
Fully automated workflow for integrated sample digestion and Evotip loading enabling high-throughput clinical proteomics2024Anders H. Kverneland, Florian Harking, Joel Mario Vej-Nielsen, Magnus Huusfeldt, Dorte B. Bekker-Jensen, Inge Marie Svane, Nicolai Bache, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, ,

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100-spd 60-spdthermo-orbitrap-astral thermo-orbitrap-exploris-480
A Novel Approach to Orthotopic Hepatocyte Transplantation Engineered With Liver Hydrogel for Fibrotic Livers, Enhancing Cell–Cell Interaction and Angiogenesis2024Daisuke Udagawa, Shogo Nagata, Hiroshi Yagi, Kotaro Nishi, Toshinori Morisaku, Shungo Adachi, Yutaka Nakano, Masayuki Tanaka, Shutaro Hori, Yasushi Hasegawa, Yuta Abe, Minoru Kitago, Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo, Japan

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Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes2024Arthur Viode, Kinga K. Smolen, Patrick van Zalm, David Stevenson, Meenakshi Jha, Kenneth Parker, Ofer Levy, Judith A. Steen, Hanno SteenDepartment of Pathology, Boston Children’s Hospital, Boston, MA, USA

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60-spdtimstof-pro-2
Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles2024Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy & Zoltán GiriczDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary

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30-spd
A proteogenomic atlas of the human neural retina2024Michael Kwint, Jolein Gloerich, Hans J.C.T. Wessels, Elfride De Baere, Filip van Nieuwerburgh, Sarah De Keulenaer, Barbara Ferrari, Stefano Ferrari, Frauke Coppieters, Frans P.M. Cremers, Erwin van Wyk, Susanne Roosing, Erik de Vrieze, Peter A.C. ‘t HoenDepartment of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands

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30-spdtimstof-pro-2
Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats2024Peipei Dou, Xiaoyi Li, Xiaoxiao Zou, Kai Wang, Lei Yao, Zhuo Sun, Hui Hong, Yongkang Luo, Yuqing TanKey Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China

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thermo-orbitrap-exploris-480
Beet supplementation mitigates post-exercise inflammation2024David C. Nieman, Camila A. Sakaguchi, James C. Williams, Fayaj A. Mulani, Patil Shivprasad Suresh, Ashraf M. Omar, Qibin ZhangHuman Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC, United States

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Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis2024Casey J. Lumpkin, Hiral Patel, Gregory K. Potts, Shilpi Chaurasia, Lauren Gibilisco, Gyan P. Srivastava, Janice Y. Lee, Nathan J. Brown, Patricia Amarante, Jon D. Williams, Eric Karran, Matthew Townsend, Dori Woods, Brinda RavikumarAbbVie, Cambridge Research Center, Cambridge, MA 02139, USA

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30-spdthermo-orbitrap-fusion-lumos
Dataset for evaluation of the lauryl maltose neopentyl glycol assisted sample preparation method2024Ryo Konno, Masaki Ishikawa, Daisuke Nakajima, Yusuke Endo, Osamu Ohara, Yusuke KawashimaDepartment of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan

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whisper-80-spdthermo-orbitrap-exploris-480
Deregulation of cellulose synthesis by site-directed mutagenesis of cellulose synthase leads to heightened bacterial cellulose production2024Daniel J. Upton, Heather Eastmond, Angharad Gatenby, Alexandra Lanot, Neil C. BruceCNAP, University of York, York, United Kingdom

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30-spdbruker-timstof-ht
Hepatocellular RECK as a Critical Regulator of Metabolic Dysfunction-Associated Steatohepatitis Development2024Ryan J. Dashek, Rory P. Cunningham, Christopher L. Taylor, Isabella Alessi, Connor Diaz, Grace M. Meers, Andrew A. Wheeler, Jamal A. Ibdah, Elizabeth J. Parks, Tadashi Yoshida, Bysani Chandrasekar, R. Scott RectorResearch Service, Harry S Truman Memorial Veterans Medical Center, Columbia

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30-spdtimstof-pro-2
Elasticity Modification of Biomaterials Used in 3D Printing with an Elastin–Silk-like Recombinant Protein2024Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chru´scielewska, Katarzyna Kosowska, Iwona Sokołowska, Natalia Łukasiewicz, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła, Marta KlakFoundation of Research and Science Development, Warsaw, Poland

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15-spdthermo-orbitrap-exploris-480
A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N labeled proteins2024Maria Wahle, Philip Remes, Vincent Albrecht, Johannes Bruno Mueller-Reif, Sophia Steigerwald, Lili Niu, Philip Loessl, Stevan Horning, Cristina Jacob, Matthias MannMax-Planck Institute for Biochemistry; Novo Nordisk Foundation Center for Protein Research, Germany, ,

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30-spd 60-spdthermo-orbitrap-astral thermo-orbitrap-exploris-480
AlphaDIA enables End-to-End Transfer Learning for Feature-Free Proteomics2024Patricia Skowronek, Vincenth Brennsteiner, Mikhail Lebedev, Marvin Thielert, Sophia Steigerwald, Mohamed Kotb, Tim Heymann, Xie-Xuan Zhou, Magnus Schwoerer, Maximilian T. Strauss, Constantin Ammar, Sander Willems, Wen-Feng Zeng, Matthias MannMax-Planck Institute for Biochemistry; Novo Nordisk Foundation Center for Protein Research, Germany,

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60-spd whisper-40spdtimstof-pro-2
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response2024Yuxin Mi, Katie L. Burnham, Philip D. Charles, Raphael Heilig, Iolanda Vendrell, Justin Whalley, Hew D. Torrance, David B. Antcliffe, Shaun M. May, Matt J. Neville, Georgina Berridge, Paula Hutton, Cyndi G. Geoghegan, Jayachandran RadhakrishnanWellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK

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100-spdtimstof-pro
Proteomic profiling reveals diagnostic signatures and pathogenic insights in multisystem inflammatory syndrome in children2024Ulrikka Nygaard, Annelaura Bach Nielsen, Kia Hee Schultz Dungu, Lylia Drici, Mette Holm, Maud Eline Ottenheijm, Allan Bybeck Nielsen, Jonathan Peter Glenthøj, Lisbeth Samsø Schmidt, Dina Cortes, Inger Merete Jørgensen, Kjeld Schmiegelow, Matthias MannDepartment of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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300-spdthermo-orbitrap-exploris-480
Circulating pre- and postprandial extracellular vesicle proteomic profiles2024Alejandra P. Garza, Elisa Wider-Eberspächer, Lorena Morton, Marco van Ham, Éva Pállinger, Edit I. Buzás, Lothar Jänsch, Ildiko Rita DunayOtto-von-Guericke University Magdeburg, Magdeburg, Germany

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60-spdtimstof-pro
Engineering of TurboID-Wingless for the identification of Wingless interactors through in vivo proximity labelling2024Ana-Miruna Androniciuc, Edward W. Tate, Jean-Paul VincentThe Francis Crick Institute, London, England, United Kingdom,

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Rapid Novor: Evosep One delivers high throughput and performance consistency in a clinical proteomics lab2024Evosep BiosystemsEvosep Biosystems

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60-spd
Multi Omics Applications in Biological Systems2024Cristian D. Gutierrez Reyes, Gerardo Alejo-Jacuinde, Benjamin Perez Sanchez, Jesus Chavez Reyes, Sherifdeen Onigbinde, Damir Mogut, Irma Hernández-Jasso, Denisse Calderón-Vallejo, J. Luis Quintanar, Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA

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thermo-orbitrap-astral
Development of an efficient, effective, and economical technology for proteome analysis2024Katherine R. Martin, Ha T. Le, Ahmed Abdelgawad, Canyuan Yang, Guotao Lu, Jessica L. Keffer, Xiaohui Zhang, Zhihao Zhuang, Papa Nii Asare-Okai, Clara S. Chan, Mona Batish, Yanbao YuDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE, USA

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thermo-orbitrap-eclipse-tribid
A co-culture system of macrophages with breast cancer tumoroids to study cell interactions and therapeutic responses2024Antonella Raffo-Romero, Lydia Ziane-Chaouche, Sophie Salomé-Desnoulez, Nawale Hajjaji, Isabelle Fournier, Michel Salzet, Marie DuhamelUniversité Lille, Inserm, CHU Lille, Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), Equipe Labellisée Ligue Contre le Cancer, Lille, France

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60-spdbruker-timstof-flex
Proteomic Characterisation of Placenta Tissue for Biomarker Discovery – Workflow Development and Application2024Tanja Peric, Selma Hevelius BounjaDepartment of biomedical engineering, Lund university, Lund, Sweden

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30-spdbruker-timstof-ht
An automated workflow based on data independent acquisition for practical and high-throughput personalized assay development and minimal residual disease monitoring in multiple myeloma patients2024Jolein Gloerich, Vincent Bonifay, Hélène Caillon, Theo M. Luider, Sven Brehmer, Lennard Pfennig, Tharan Srikumar, Dennis Trede, Gary Kruppa, Thomas Dejoie, Martijn M. van Duijn, Alain J. van Gool, Joannes F.M. Jacobs, Hans J.C.T. WesselsLaboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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60-spdtimstof-pro-2
UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF1682024Daniel Salas-Lloret, Inge de Krijger, Nathalie Moatti, Ruben van der Lugt, Mattia Falcone, Aurora Cerutti, Onno B. Bleijerveld, Liesbeth Hoekman, Román González-Prieto & Jacqueline J. L. JacobsDivision of Oncogenomics, The Netherlands Cancer Institute, Amsterdam, the Netherlands

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Evotip Pure brings innovative sample storage2024Evosep BiosystemsEvosep Biosystems,

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Whisper Zoom drives scalable workflows2024Evosep BiosystemsEvosep Biosystems,

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whisper-zoom-120-spd whisper-zoom-80-spdtimstof-pro-2
Unlocking the plasma proteome2024Evosep BiosystemsEvosep Biosystems

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100-spdthermo-orbitrap-astral
Whisper Zoom2024Evosep BiosystemsEvosep Biosystems, , ,

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A specialized method for high sensitivity with the Whisper Zoom 120 samples per day method2024Evosep BiosystemsEvosep Biosystems

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A specialized method for high sensitivity with the Whisper Zoom 80 samples per day method2024Evosep BiosystemsEvosep Biosystems

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A specialized method for high sensitivity with the Whisper Zoom 40 samples per day method2024Evosep BiosystemsEvosep Biosystems

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A specialized method for high sensitivity with the Whisper Zoom 20 samples per day method2024Evosep BiosystemsEvosep Biosystems

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Efficient proteomics with an automated sample preparation strategy leveraged by Evotip Pure and the AssayMAP Bravo2024Evosep BiosystemsEvosep Biosystems, , ,

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100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spdbruker-timstof-ht
Cost-efficient and scalable end-to-end workflow on the Opentrons OT-2 for neat plasma utilizing Evotip Pure2024Evosep BiosystemsEvosep Biosystems,

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100-spd 200-spdbruker-timstof-ht
Scalability for high-throughput proteomics – Evotip Pure integration with the Biomek i5 liquid handler2024Evosep BiosystemsEvosep Biosystems,

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200-spd 500-spdbruker-timstof-ht
Standardized, fully automated neat plasma and Mag-Net enrichment workflows enabled by the Evotip Pure2024Joel Vej-Nielsen, Magnus Huusfeldt, Ian D. Shoemaker, Stoyan Stoychev, Laurent Rieux, Dorte B. Bekker-Jensen, Nicolai BacheEvosep Biosystems,

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200-spd 500-spdbruker-timstof-ht
A complete and automated end-to-end sample preparation strategy for high-throughput and standardized proteomics with high sensitivity2024Magnus Huusfeldt, Hope Cabalo Zisco, Gabriel Bracamontes, Dorte B. Bekker-Jensen, Nicolai BacheEvosep Biosystems, , ,

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100-spd 500-spd whisper-zoom-40-spd whisper-zoom-80-spdbruker-timstof-ht
Enabling scalable single-cell proteomics by utilizing the unique analytical properties of the Evotip Pure with new Whisper Zoom methods2024Frederik Haugaard Vrdlovec Holck, David Hartlmayr, Anjali Seth, Danté Johnson, Ole B. Hørning, Dorte B. Bekker-Jensen, Nicolai BacheEvosep Biosystems, ,

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Highly Repeatable Tissue Proteomics for Kidney Transplant Pathology: Technical and Biological Validation of Protein Analysis using LC-MS/MS2024Rianne Hofstraat, Kristina Marx, Renata Blatnik, Nike Claessen, Aleksandra Chojnacka, Hessel PetersSengers, Sandrine Florquin, Jesper Kers, Garry CorthalsDepartment of Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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60-spdbruker-timstof-ht
Single cell proteomics by mass spectrometry reveals deep epigenetic insight into the actions of an orphan histone deacetylase inhibitor2024Benjamin C. OrsburnThe Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA,, , , ,

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100-spd 200-spd 30-spd 500-spd 60-spdbruker-timstof-scp
Evolocumab as an immunomodulator in glioma: A window of opportunity trial evaluating PCSK9 inhibition to enhance surface MHC-I on tumor2024Allan Friedman, Stephen Keir, Evan D. Buckley, James E. Herndon, Roger E. McLendon, John H. Sampson, Evan Calabrese, Giselle Y. Lopez, Gerald A. Grant, Anoop P. Patel, Chuan-Yuan Li, Peter E. Fecci, Mustafa KhasrawThe Preston Robert Tisch Brain Tumor Center at Duke University, Durham, NC, US,

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100-spd 60-spdthermo-orbitrap-astral
Spatial proteomics of skeletal muscle using thin cryosections reveals metabolic adaptation at the muscle-tendon transition zone2024Luisa Schmidt, Michael Saynisch, Christian Hoegsbjerg, Andreas Schmidt, Abigail Mackey, Jan-Wilm Lackmann, Stefan Müller, Manuel Koch, Bent Brachvogel, Michael Kjaer, Philipp Antczak, Marcus KrügerInstitute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany,

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timstof-pro-2 thermo-orbitrap-eclipse-tribid
Discovery of a novel antifungal compound, ilicicolin K, through genetic activation of the ilicicolin biosynthetic pathway in Trichoderma reesei2024Isabella Burger, Matthias Schmal, Kathrin Peikert, Lukas Fourtis, Christoph Suster, Christian Stanetty, Dominik Schnalzer, Ruth Birner-Gruenberger, Robert L Mach, Astrid R. Mach-Aigner, Matthias Schittmayer, Christian ZimmermannInstitute of Chemical Technologies and Analytics, TU Wien, Vienna, Austria

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Nivolumab reaches brain lesions in patients with recurrent glioblastoma and induces T-cell activity and upregulation of checkpoint pathways2024Filip Mundt, Vilde Pedersen, Matthias Mann, Ib Jarle Christensen, Jane Skjøth-Ramussen, Christina Westmose Yde, Bjarne Winther Kristensen, Hans Skovgaard Poulsen, Benedikte Hasselbalch, Inge Marie Svane, Ulrik Lassen, Sine Reker HadrupExperimental and Translational Immunology, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark

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30-spdtimstof-pro
Spatial Proteomics of Single Hepatocytes with Multiplexed Data-Independent Acquisition (mDIA)2024Marvin Thielert, Caroline A. M. Weiss, Matthias Mann & Florian A. RosenbergerProteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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Visfatin impact on the proteome of porcine luteal cells during implantation2024Grzegorz Kopij, Marta Kiezun, Marlena Gudelska, Kamil Dobrzyn, Barbara Zarzecka, Edyta Rytelewska, Ewa Zaobidna, Bianka Swiderska, Agata Malinowska, Agnieszka Rak, Tadeusz Kaminski & Nina SmolinskaFaculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

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30-spdthermo-orbitrap-exploris-480
Localized K63 ubiquitin signaling is regulated by VCP/p97 during oxidative stress2024Austin O. Maduka, Sandhya Manohar, Matthew W. Foster, and Gustavo M. SilvaDepartment of Biology, Duke University, Durham, NC, USA,

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Dysregulation of Lipid Metabolism Serves as A Link Between Alzheimer’s and Cardiovascular Disease, As Witnessed in A Cross-Sectional Study2024Cristina Juarez-Alia1, Tamara Sastre-Oliva, Inés Perales-Sánchez, German Hernandez-Fernandez, Eduardo Chicano-Galvez, Ángela Peralbo-Molina, Felipe Madruga, Emilio Blanco-Lopez, Teresa Tejerina, María G. BarderasDepartment of Vascular Physiopathology, Hospital Nacional de Paraplejicos, SESCAM, Toledo, Spain

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bruker-timstof-flex
Rhythmic variation in proteomics: challenges and opportuninites for statistical power and biomarker identification2024Matt Spick, Cheryl M. Isherwood, Lee Gethings, Hana Hassanin, Daan R. van der Veen, Debra J. Skene, Jonathan D. JohnstonSchool of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK

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60-spd
Data for proteomic analysis of in situ digestion of alcohol-fixed cells for quantitative proteomics2024Atsushi Hatano, Masaki MatsumotoDepartment of Omics and Systems Biology, Graduate School of Medical and Dental Sciences, Niigata University, Ichibancho, Asahimachi-dori, Chuo-ku, Niigata City, Niigata, Japan,

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thermo-orbitrap-exploris-480 thermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Quantitative measurement of lacritin in the tear fluid of patients with Dry Eye Disease2024Kyla Frenia, Ketan Dinghe, Yunxiang Fu, Jaclyn Sikora, Kathleen Garwood, Rick Mental, Dipanjan Pan, Kevin Xiao, Leanne LabriolaInnSight Technology Inc, Pittsburgh, Pennsylvania, United States

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timstof-pro-2
Culturing Conditions Dictate the Composition and Pathways Enrichment of Human and Rat Perirenal Adipose-Derived Stromal Cells’ Secretomes2024Erika Pinheiro-Machado, Marijke M. Faas, Bart J. de Haan, Cyril Moers & Alexandra M. SminkDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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30-spdthermo-orbitrap-exploris-480
Early Holocene preservation differences between cortical and trabecular bone proteomes2024Ragnheiður Diljá Ásmundsdóttir, Jakob Hansen, Zandra Fagernäs, Gaudry Troché, Jesper V. Olsen, Maria Saña Seguí, Frido WelkerGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,

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60-spdbruker-timstof-flex thermo-orbitrap-exploris-480
Biophysical characteristics of NFkappaB-IkappaBalpha’s Intrinsically Disordered Regions2024Luis OlivaUniversity of California San Diego, CA, United States

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thermo-orbitrap-exploris-480
Towards routine proteome profiling of FFPE tissue: Insights from a 1,200 case pan-cancer study2024Lisa Hönikl, Vicki Butenschön, Rumyana Todorova, Hilka Rauert-Wunderlich, Matthew The, Andreas Rosenwald, Volker Heinemann, Julian Holch, Bernhard Meyer, Wilko Weichert, Carolin Mogler, Peer Hendrik-Kuhn, Bernhard KusterProteomics and Bioanalytics, School of Life Sciences, Technical University of Munich, Freising, Germany, ,

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100-spd 15-spd 30-spdthermo-orbitrap-exploris-480
VfENko-Kae01 is a flagellum-specific jumbo phage infecting Klebsiella aerogenes2024Kira Ranta, Mikael Skurnik & Saija KiljunenHuman Microbiome Research Program, Research Program Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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60-spdtimstof-pro
Population scale proteomics enables adaptive digital twin modelling in sepsis2024Aaron M. Scott, Lisa Mellhammar, Erik Malmström, Axel Goch Gustafsson, Anahita Bakochi, Marc Isaksson, Tirthankar Mohanty, Louise Thelaus, Fredrik Kahn, Lars Malmström, Johan Malmström, Adam LinderDivision of Infection Medicine, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden

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60-spdtimstof-pro-2
Repurposed 3D Printer Allows Economical and Programmable Fraction Collection for Proteomics of Nanogram Scale Samples2024Eduardo S. Kitano, Gareth NisbetYana Demyanenko, Katarzyna M Kowalczyk, Louisa Iselin, Stephen Cross, Alfredo Castello, Shabaz MohammedRosalind Franklin Institute, Harwell Campus, Didcot, United Kingdom

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30-spdthermo-orbitrap-ascend-tribid
Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study2024Siyabonga Khoza, Jaya A. George, Previn Naicker, Stoyan H. Stoychev, June Fabian, Ireshyn S. GovenderDepartment of Chemical Pathology, National Health Laboratory Service and School of Pathology, University of the Witwatersrand, Faculty of Health Sciences, Johannesburg, South Africa

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60-spd
Facing death: a multidisciplinary analysis of a Romano-Egyptian mummy mask at the Ny Carlsberg Glyptotek, Copenhagen2024Tuuli Kasso, Jens Stenger, Caterina Zaggia, Gianluca Pastorelli, Max Ramsøe, Tina Ravnsborg, Ole N. Jensen, Elsa Yvanez, Chiara Spinazzi-Lucchesi, Matthew J. Collins & Cecilie BrønsNy Carlsberg Glyptotek, Copenhagen, Denmark

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60-spdthermo-q-exactive-hf
Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway2024Rubén Rodríguez-Agudo, Sofía Lachiondo-Ortega, Maria Mercado-Gómez, Teresa C. Delgado, Marina Porcelli, Igor Aurrekoetxea, James D. Sutherland, Rosa Barrio, Dimitris Xirodimas, Patricia Aspichueta, Felix Elortza, María L. Martínez-ChantarLiver Disease Lab, CIC bioGUNE, Basque Research and Technology Alliance, BRTA, Bizkaia, Spain

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timstof-pro
Differences in the cerebral amyloid angiopathy proteome in Alzheimer’s disease and mild cognitive impairment2024Dominique Leitner, Tomas Kavanagh, Evgeny Kanshin, Kaleah Balcomb, Geoffrey Pires, Manon Thierry, Jianina I. Suazo, Julie Schneider, Beatrix Ueberheide, Eleanor Drummond & Thomas WisniewskiCenter for Cognitive Neurology, New York University Grossman School of Medicine, New York, NY, USA

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15-spdthermo-q-exactive-hf
Comparative Proteomics and Metabonomics Analysis of Different Diapause Stages Revealed a New Regulation Mechanism of Diapause in Loxostege sticticalis (Lepidoptera: Pyralidae)2024Lijun Shao, Fangzheng Yue, Jinfu Fan, Qin Su, Hairui Liu, Quanyi Zhang and Linbo XuInstitute of Grassland Research, Chinese Academy of Agricultural Sciences, Hohhot, China

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thermo-orbitrap-exploris-480
The PP2A regulator IER5L supports prostate cancer progression2024Ianire Astobiza, Amaia Zabala-Letona, Marc Guiu, Mikel Azkargorta, Monika Gonzalez-Lopez, Nuria Macías-Cámara, Phuong Doan, Félix Elortza, Isabel Mendizabal, Jukka Westermack, Roger R. Gomis, Amaia Ercilla & Arkaitz CarracedoCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain

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30-spdtimstof-pro
Unraveling the differential mechanisms of revascularization promoted by MSCs & ECFCs from adipose tissue or umbilical cord in a murine model of critical limb-threatening ischemia2024Marta Rojas-Torres, Lucía Beltrán-Camacho, Ana Martínez-Val, Ismael Sánchez-Gomar, Sara Eslava-Alcón, Antonio Rosal-Vela, Margarita Jiménez-Palomares, Esther Doiz-Artázcoz, Mario Martínez-Torija, Rafael Moreno-Luna, Jesper V. Olsen & Ma. Carmen Duran-RuizBiomedicine, Biotechnology and Public Health Department, University of Cadiz, Cadiz, Spain

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30-spdthermo-orbitrap-exploris-480
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics2024Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. BushCrick-GSK Biomedical LinkLabs, GSK, Gunnels Wood Road, Stevenage, Hertfordshire, UK,

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30-spd 60-spdtimstof-pro-2
Plasma proteome profiling for AKI biomarker candidates associated with first-line ART in people living with HIV in South Africa2024Rethabile J. Mokoenaa, Sylvia Fanucchib, Firdaus Nabeemeeahd, Ebrahim Variavad, Neil Martinsond, Ireshyn S. Govendera and Previn NaickeraNextGen Health, Council of Scientific and Industrial Research, Pretoria, Gauteng, South Africa

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60-spd
A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway2024J. Huang, A. Jaekel, J. van den Boom, D. Podlesainski, M. Elnaggar, A. Heuer-Jungemann, M. Kaiser, H. Meyer & B. SaccàBionanotechnology, CENIDE and ZMB, University of Duisburg-Essen, Essen, Germany,

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100-spd 60-spd
Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes2024Lisa M. Sevilla, Omar Pons-Alonso, Andrea Gallego, Mikel Azkargorta, Félix Elortza & Paloma PérezInstituto de Biomedicina de Valencia (IBV-CSIC), Department of Pathology and Molecular and Cell Therapy, Valencia, Spain

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30-spdtimstof-pro
Substrate O-glycosylation actively regulates extracellular proteolysis2024Elizabeta Madzharova, Fabio Sabino, Konstantinos Kalogeropoulos, Chiara Francavilla, Ulrich auf dem KellerDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark

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whisper-80-spdthermo-orbitrap-exploris-480
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage2024Sara Diana Lolansen, Nina Rostgaard, Markus Harboe Olsen, Maud Eline Ottenheijm, Lylia Drici, Tenna Capion, Nicolas Hernandez Nørager, Nanna MacAulay & Marianne JuhlerDepartment of Neurosurgery, the Neuroscience Centre, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark

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thermo-orbitrap-exploris-480
Privacy-Preserving Multi-center Differential Protein Abundance Analysis with FedProt2024Julian Späth, Richard Röttger, Veit Schwämmle, Stefanie M. Hauck, Stefan Lichtenthaler, Axel Imhof, Matthias Mann, Christina Ludwig, Bernhard Kuster, Jan Baumbach, Olga ZolotarevaChair of Proteomics and Bioanalytics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany, , ,

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30-spdtimstof-pro thermo-orbitrap-exploris-480 thermo-orbitrap-fusion-lumos thermo-q-exactive-hf
Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice2024Jason R. Pitarresi, Dikla Atias, Eliana Steinberg, Tirza Bidany-Mizrahi, Esther Forkosh, Lior H. Katz, Ofra Benny, Talia Golan, Matan Hofree, Sheila A. Stewart, Karine A. Atlan, Gideon Zamir, Ben Z. Stanger, Michael Berger & Ittai Ben-PorathDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

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15-spdthermo-orbitrap-exploris-480
Comparison of the Amyloid Plaque Proteome in Down Syndrome, Early-Onset Alzheimer’s Disease and Late-Onset Alzheimer’s Disease2024Mitchell Martá-Ariza, Dominique F Leitner, Evgeny Kanshin, Jianina Suazo, Ana Giusti Pedrosa, Manon Thierry, Edward B. Lee, Orrin Devinsky, Eleanor Drummond, Juan Fortea, Alberto Lleó, Beatrix Ueberheide, Thomas WisniewskiNew York University Grossman School of Medicine

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15-spdthermo-q-exactive-hf-x
Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments2024Francisco Romero-Gavilán, Carlos Arias-Mainer, Andreia Cerqueira, David Peñarrocha-Oltra, Juan Carlos Bernabeu-Mira, Iñaki García-Arnáez, Félix Elortza, María Muriach, Mariló Gurruchaga, Isabel Goñi & Julio SuayDepartment of Industrial Systems Engineering and Design, Universitat Jaume I, Castellón de la Plana, Spain

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timstof-pro
Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers2024Yaohui Sun, Zhiming Gan, Xiaojin Wang, Jian Liu, Wei Zhong, Zhiyan Zhang, Jiebin Zuo, Hang Zhong, Xiuting Huang, Zhixiang Yan & Qingdong CaoDepartment of Thoracic Surgery and Lung Transplantation, The Fifth Affiliated Hospital of Sun Yat-Sen University, Guangdong, China

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30-spdthermo-orbitrap-fusion-lumos
De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments2024Sam P. B. van Beljouw, Marcin Skwark, Andreas Hougaard Laustsen, Stan J. J. Brouns, Anne Ljungers, Erwin M. Schoof, Jeroen Van Goey, Ulrich auf dem Keller, Karim Beguir, Nicolas Lopez Carranza and Timothy P. JenkinsInstaDeep Ltd, 5 Merchant Square, London, UK

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whisper-40spdthermo-orbitrap-exploris-480
Comparison of the Proteome of Huh7 Cells Transfected with Hepatitis B Virus Subgenotype A1, with or without G1862T2024Kiyasha Padarath, Aurélie Deroubaix, Previn Naicker, Stoyan Stoychev and Anna KramvisHepatitis Virus Diversity Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Science, University of Witwatersrand, Johannesburg, South Africa

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Cryoprotectant-specific alterations in the proteome of Siberian sturgeon spermatozoa induced by cryopreservation2024Natalia Kodzik, Andrzej Ciereszko, Sylwia Judycka, Mariola Słowińska, Bożena Szczepkowska, Bianka Świderska & Mariola A. DietrichDepartment of Gamete and Embryo Biology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland

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extended-methodthermo-orbitrap-exploris-480
A non-autonomous protein quality control mechanism targeting tau aggregate propagation2024Nina Schulzea, Michal Strzalaa, Michelle Kocia, Farnusch Kaschania, Markus Kaisera, Michael Erkelenzc, Sebastian Schlueckerc, Melisa Merdanovica, Simon Poepseld, Doris Hellerschmieda, Steve Burstonf and Michael EhrmannCenter of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Germany

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60-spdthermo-orbitrap-fusion-lumos
Whole genome sequencing, proteomics, and function characterization of the Sinclair Nanopig™ for (bio) pharmaceuticals safety assessment2024Yafei Chen, Wendell P. DavisAltasciences

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timstof-pro-2
Stage-dependent phosphoproteome remodeling of Parkinson’s disease blood cells2024Giorgia Massacci, Veronica Venafra, Maximilian Zwiebel, Maria Wahle, Rocco Cerroni, Jacopo Bissacco, Livia Perfetto, Vito Michienzi, Alessandro Stefani, Nicola Biagio Mercuri, Tommaso Schirinzi, Francesca SaccoDepartment of Biology, University of Rome Tor Vergata, Rome, Italy

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bruker-timstof-ultra
Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer2024Yuqiu Shen, Oleta T. Johnson, Gabriela Grigorean, Brett Phinney, Liangren Liu, Qiang Wei, Eva Corey, Clifford G. Tepper, Hong-Wu Chen, Christopher P. Evans, Marc A. Dall’Era, Allen C. Gao, Jason E. Gestwicki & Chengfei LiuDepartment of Urologic Surgery, University of California, Davis, CA, USA

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bruker-timstof-ht
Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells2024Kaisa-Mari Launonen, Vera Varis, Niina Aaltonen, Einari A Niskanen, Markku Varjosalo, Ville Paakinaho, Jorma J PalvimoInstitute of Biomedicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland

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60-spdtimstof-pro
Deep Visual Proteomics reveals DNA replication stress as a hallmark of Signet Ring Cell Carcinoma2024Sonja Kabatnik, Xiang Zheng, Georgios Pappas, Sophia Steigerwald, Matthew P Padula, Matthias MannNNF Center for Protein Research, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark

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whisper-40spdthermo-orbitrap-astral
An Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition2024Hui Jing, Paul L. Richardson, Gregory K. Potts, Sameera Senaweera, Violeta L Marin, Ryan McClure, Adam Banlasan, Hua Tang, James E. Kath, Renze Ma, Jon D. WilliamsDiscovery Research, AbbVie, Inc., 1 North Waukegan Rd., North Chicago, Illinois, United States

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30-spdthermo-orbitrap-exploris-480
The nonphototrophic hypocotyl 3 (NPH3) domain protein NRL5 is a trafficking-associated GTPase essential for drought resistance2024Neha Upadhyay-Tiwari, Xin-Jie Huang, Yi-Chen Lee, Shashi Kant Singh, Chuan-Chi Hsu, Shih-Shan Huang, and Paul E. VersluesInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan

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extended-methodbruker-timstof-ht
The proteomic landscape of in vitro cultured endothelial cells across vascular beds2024Stijn A. Groten, Eva R. Smit, Maartje van den Biggelaar & Arie J. HoogendijkDepartment of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

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extended-methodthermo-orbitrap-fusion-lumos
Distinct protein patterns related to postnatal development in small for gestational age preterm infants2024Eva R. Smit, Michelle Romijn, Pieter Langerhorst, Carmen van der Zwaan, Hilde van der Staaij, Joost Rotteveel, Anton H. van Kaam, Suzanne F. Fustolo-Gunnink, Arie J. Hoogendijk, Wes Onland, Martijn J. J. Finken & Maartje van den BiggelaarDepartment of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands

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30-spdthermo-orbitrap-fusion-lumos
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome2024Alžběta Roeselová, Sarah L. Maslen, Jessica Zhiyun He, Gabija Jurkeviciute, J. Mark Skehel, Radoslav Enchev, David BalchinProtein Biogenesis Laboratory, The Francis Crick Institute, London, UK

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30-spdthermo-orbitrap-fusion-lumos
Identification of a biomarker to predict doxorubicin/cisplatin chemotherapy efficacy in osteosarcoma patients using primary, recurrent and metastatic specimens2024Qiong Ma, Jin Sun, Qiao Liu, Jin Fu, Yanhua Wen, Fuqin Zhang, Yonghong Wu, Xiaoyu Zhang, Li Gong, Wei ZhangDepartment of Pathology, Tangdu Hospital, Air Force Medical University, Xi'an 710038, China

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thermo-orbitrap-exploris-480
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration2024Hyunggu Hahn, Carole Daly, John Little IV, Nicole A Perry-Hauser, Emmanuel Flores-Espinoza, Asuka Inoue, Bianca Plouffe, Alex Rojas Bie ThomsenDepartment of Molecular Pathobiology, New York University College of Dentistry, New York, United States

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extended-methodthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Multi-omics analysis reveals the impact of influenza a virus host adaptation on immune signatures in pig tracheal tissue2024Chrysillis Hellemann Polhaus, Charlotte Kristensen, Betina Lyngfeldt Henriksen, Yaolei Zhang, Louise Brogaard, Cathrine Agnete Larsen, Ramona Trebbien, Lars Erik Larsen, Kalogeropoulos Kalogeropoulos, Ulrich auf dem Keller, Kerstin SkovgaardDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark

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thermo-orbitrap-exploris-480
The Comparative Analysis of Peptides in Enteral Nutrition Products and Foods for Special Medical Purposes2024Hao Li, Chenlu Fang, Yushan Hu, Jing Xu, Wei Zhao and Li LiState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China

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thermo-orbitrap-exploris-120
Synaptic synergy of T cell receptor and interleukin 2 receptor in 2 CD8+ T cells2024Jesusa Capera, Ashwin K Jainarayanan, Salvatore Valvo, Lina Chen, Steven N Quayle, Raymond J Moniz , Anish Suri, Michael L DustinThe Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

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timstof-pro
Distinct protein patterns related to postnatal development in small for gestational age preterm infants2024Eva R. Smit, Michelle Romijn, Pieter Langerhorst, Carmen van der Zwaan, Hilde van der Staaij, Joost Rotteveel, Anton H. van Kaam, Suzanne F. Fustolo-Gunnink, Arie J. Hoogendijk, Wes Onland, Martijn J. J. Finken & Maartje van den BiggelaarDepartment of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands

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30-spdthermo-orbitrap-fusion-lumos
Machine learning-based analysis identifies and validates serum exosomal proteomic signatures for the diagnosis of colorectal cancer Refining Spatial Proteomics by Mass Spectrometry: An Efficient Workflow Tailored for Archival Tissue2024Haofan Yin, Jinye Xie, Shan Xing, Xiaofang Lu, Yu Yu, Yong Ren, Jian Tao, Guirong He, Lijun Zhang, Xiaopeng Yuan, Zheng Yang, Zhijian HuangDepartment of Pathology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China

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30-spdtimstof-pro
Peptide clustering enhances large-scale analyses and reveals proteolytic signatures in mass spectrometry data2024Erik Hartman, Fredrik Forsberg, Sven Kjellström, Jitka Petrlova, Congyu Luo, Aaron Scott, Manoj Puthia, Johan Malmström & Artur SchmidtchenDivision of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden,

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30-spdbruker-timstof-ht timstof-pro
An Inflection Point in High-Throughput Proteomics with Orbitrap Astral: Analysis of Biofluids, Cells, and Tissues2024Nathan G. Hendricks, Santosh D. Bhosale, Angel J. Keoseyan, Josselin Ortiz, Aleksandr Stotland, Saeed Seyedmohammad, Chi D. L. Nguyen, Jonathan T. Bui, Annie Morandian, Susan M. Mockus, Jennifer E. van EykPrecision Biomarker Laboratories, Cedars-Sinai Medical Center, Beverly Hills, California, United States

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thermo-orbitrap-astral
Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy2024Fiona Dick, Gard Aasmund Skulstad Johanson, Ole-Bjørn Tysnes, Guido Alves, Christian Dölle & Charalampos TzoulisNeuro-SysMed Center of Excellence for Clinical Research in Neurological Diseases, Department of Neurology, Haukeland University Hospital, Bergen, Norway

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30-spdthermo-orbitrap-eclipse-tribid
Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer2024Haleema Azam, Colin Veale, Kim Zitzmann, Simone Marcone, William M. Gallagher, Maria PrencipeCancer Biology and Therapeutics Laboratory, Conway Institute of Biomolecular and Biomedical Research, University College Dublin

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30-spdtimstof-pro
vPro-MS enables identification of human-pathogenic viruses from patient samples by untargeted proteomics2024Marica Grossegesse, Fabian Horn, Andreas Kurth, Peter Lasch, Andreas Nitsche, Joerg DoellingerRobert Koch Institute, Centre for Biological Threats and Special Pathogens: Highly Pathogenic Viruses (ZBS 1), WHO Collaboration Center for Emerging Treats and Special Pathogens,

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60-spdbruker-timstof-ht thermo-orbitrap-astral
SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster2024Amrit S. Boese, Bryce M. Warner, Peter McQueen, Robert Vendramelli, Nikesh Tailor, Bryan D. Griffin, Mable Chan, Jonathan Audet, Anders Leung, Stuart McCorrister, Chris Grant, Garrett Westmacott & Darwyn KobasaSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada

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whisper-20spdthermo-orbitrap-exploris-480
HSP110 is a modulator of amyloid beta (Aβ) aggregation and proteotoxicity2024Sabrina Montresor, Maria Lucia Pigazzini, Sudarson Baskaran, Mira Sleiman, Govinda Adhikari, Lukas Basilicata, Luca Secker, Natascha Jacob, Yara Ehlert, Anushree Kelkar, Gurleen Kaur Kalsi, Niraj Kulkarni, Paul Spellerberg, Janine KirsteinLeibniz Institute on Aging—Fritz-Lipmann-Institute, Jena, Germany

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30-spdthermo-orbitrap-exploris-480
WHIX is a T6SS secretion domain found in polymorphic double-edged sword effectors2024Chaya Mushka Fridman, Kinga Keppel, Vladislav Rudenko, Jon Altuna-Alvarez, David Albesa-Jové, Eran Bosis, & Dor SalomonDepartment of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical 8 and Health Sciences, Tel Aviv University, Tel Aviv, Israel

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30-spdthermo-q-exactive-hf
An unconventional TOG domain is required for CLASP localization2024Nelly Gareil, Alison Gervais, Nicolas Macaisne, Guillaume Chevreux, Julie C. Canman, Jessica Andreani, Julien DumontUniversité Paris Cité, CNRS, Institut Jacques Monod, Paris, France

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30-spdtimstof-pro-2
An NADH-controlled gatekeeper of ATP synthase2024Vasileios R Ouzounidis, Kate Jeffrey, Daniel-Cosmin Marcu, Francis J O’Reilly, Andrea Graziadei, Marchel Stuiver, Kita Schmidt, Helge Ewers, Christian MT Spahn, Ezgi Karaca, Karl Emanuel Busch, Dhanya Cheerambathur, David Schwefel, Juri RappsilberTechnische Universität Berlin, Chair of Bioanalytics, Berlin, Germany,

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60-spdbruker-timstof-ultra thermo-orbitrap-fusion-lumos
Plasma proteomics and lipidomics facilitate elucidation of the link between Alzheimer’s disease development and vessel wall fragility2024Suzumi M. Tokuoka, Fumie Hamano, Ayako Kobayashi, Shungo Adachi, Tomohiro Andou, Tohru Natsume & Yoshiya OdaDepartment of Lipidomics, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

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thermo-q-exactive-hf
Pollen-Food Allergy Syndrome: From Food Avoidance to Deciphering the Potential Cross-Reactivity between Pru p 3 and Ole e 72024Paula Álvarez, Rocío Aguado, Juan Molina, Antonio Trujillo-Aguilera, Mayte Villalba, Araceli Díaz-Perales, Carmen Oeo-Santos, Eduardo Chicano, Nadine Blanco, Ana Navas, Berta Ruiz-León, and Aurora JuradoDepartment of Immunology and Allergy, Reina Sofía University Hospital, Córdoba, Spain

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60-spdbruker-timstof-pro
Loss of Lipooligosaccharide Synthesis in Acinetobacter baumannii Produces Changes in Outer Membrane Vesicle Protein Content2024Beatriz Cano-Castaño, Andrés Corral-Lugo, Eva Gato, María C. Terrón, Antonio J. Martín-Galiano, Javier Sotillo, Astrid Pérez, and Michael J. McConnellIntrahospital Infections Laboratory, Instituto de Salud Carlos III (ISCIII), National Centre for Microbiology, Madrid, Spain

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100-spdbruker-timstof-flex
Automated multiplexed affinity-based enrichment of peptides for LC-MS/MS plasma proteomics2024Sergio Mosquim Junior, Fredrik LevanderDepartment of Immunotechnology, Lund University, Lund, Sweden

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30-spdthermo-q-exactive-hf-x
hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis2024Abdolhossein Zare, Saeede Salehi, Jakob Bader, Cornelius Schneider, Utz Fischer, Alexander Veh, Panagiota Arampatzi, Matthias Mann, Michael Briese & Michael SendtnerInstitute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg, Germany,

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whisper-40spdbruker-timstof-pro bruker-timstof-scp
A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth2024Yuliya Kurlishchuk, Anita Cindric Vranesic, Marco Jessen, Alexandra Kipping, Christin Ritter, KyungMok Kim, Paul Cramer & Björn von EyssLeibniz-Institut für Altersforschung Fritz-Lipmann-Institut eV: Jena, Thüringen, Germany

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60-spdthermo-orbitrap-exploris-480
Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties2024Unai Mendibil, Yaiza Lópiz-Morales, Blanca Arnaiz, Raquel Ruiz-Hernández, Pablo Martín, Desiré Di-Silvio, Nerea Garcia-Urquia, Felix Elortza, Mikel Azkargorta, Beatriz Olalde, Ander AbarrategiCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), Donostia-San Sebastian, Spain

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30-spdbruker-timstof-pro
Glutathione peroxidase 3 is a potential biomarker for konzo2024Vincent Kambale-Mastaki, Rafael Vincent M. Manalo, Aliyah Mohammed, David R. McIlwain, Gary Cunningham, Marshall Summar, Michael J. Boivin, Ljubica Caldovic, Eric Vilain, Dieudonne Mumba-Ngoyi, Desire Tshala-Katumbay & Arnaud DroitComputational Biology Laboratory and The Proteomics Platform, CHU de Québec - Université Laval Research Center, Québec City, QC, Canada

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Tea Polyphenols Inhibit Methanogenesis and Improve Rumen Epithelial Transport in Dairy Cows2024Zhanwei Teng, Shuai Liu, Lijie Zhang, Liyang Zhang, Shenhe Liu, Tong Fu, Ningning Zhang, and Tengyun GaoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China,

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The coral pathogen Vibrio coralliilyticus uses a T6SS to secrete a group of novel anti-eukaryotic effectors that contribute to virulence2024Shir Mass, Hadar Cohen, Ram Podicheti, Douglas B. Rusch, Motti Gerlic, Blake Ushijima, Julia C. van Kessel, Eran Bosis, Dor SalomonDepartment of Clinical Microbiology and Immunology, School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel

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Pseudouridine guides germline small RNA transport and epigenetic inheritance2024Rowan P. Herridge, Jakub Dolata, Valentina Migliori, Cristiane de Santis Alves, Filipe Borges, Andrea J. Schorn, Frédéric van Ex, Ann Lin, Mateusz Bajczyk, Jean-Sebastien Parent, Tommaso Leonardi, Alan Hendrick, Tony Kouzarides & Robert A. MartienssenHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA,

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Quantitation of Host Cell Proteins by Capillary LC/IMS/MS/MS in Combination with Rapid Digestion on Immobilized Trypsin Column Under Native Conditions2024Ryota Tomioka, Kosuke Ogata, and Yasushi IshihamaGraduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan

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Cell-specific models reveal conformation-specific RAF inhibitor combinations that synergistically inhibit ERK signaling in pancreatic cancer cells2024Thomas Sevrin, Hiroaki Imoto, Sarah Robertson, Nora Rauch, Uscinnia Dyn’ko, Katerina Koubova, Kieran Wynne, Walter Kolch, Oleksii S. Rukhlenko, Boris N. KholodenkoSystems Biology Ireland, University College Dublin, Dublin, Ireland

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A Multiomics Evaluation of theCountermeasure Influence of 4-Weeks Cranberry Beverage Supplementationon Exercise-Induced Changes in InnateImmunity2024David Christopher Nieman, Camila A Sakaguchi, James C Williams, Jongmin Woo, Ashraf M Omar,Fayaj A Mulani, Qibin Zhang, Wimal Pathmasiri, Blake R Rushing, Susan McRitchie, Susan J Sumner, Jackie Lawson, Kevin C LambirthHuman Performance Laboratory, Appalachian State University, North Carolina Research Campus(NCRC), Kannapolis, NC, USA

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Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate2024Irina Nelepcu, Mona Marzban, Htoo Zarni Oo, Maj Sofie Ørum-Madsen, Yuzhuo Wang, Morten A. Nielsen, Henrik Clausen, Michael Wierer, Dominik Wolf, Ismail Gögenur, Thor G. Theander, Nader Al-Nakouzi, Tobias Gustavsson, Mads Daugaard & Ali SalantiCentre for Translational Medicine and Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Exceeding 1000 cells per day – scalable single cell analysis using the Evosep Whisper Zoom method on the timsTOF Ultra 22024Christoph Krisp, Dorte Bekker-Jensen, Ole Bjeld Hørning, Nicolai Bache, Torsten Müller, Markus Lubeck, Daniel HornburgBruker Daltonics GmbH & Co. KG, Bremen, Germany

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Rapid amelogenin sex estimation of human and cattle remains using untargeted Evosep-timsTOF mass spectrometry2024Charllotte Blacka, Adam Dowle, Mik Lisowski, Michelle Alexander, Jessica Hendy, Kirsty Penkman, Jackie MoselyUniversity of York Department of Chemistry

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Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage2024Tiangen Chang, Carmela Rubolino, Kathrin Laue, Yael Cohen-Sharir, Simone Scorzoni, Silvia Taglietti, Alice Ratti, Chani Stossel, Talia Golan, Francesco Nicassio, Eytan Ruppin, Markus Ralser, Francisca Vazquez, Uri Ben-David & Stefano SantaguidaDepartment of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Milan, Italy

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Plasma proteomes of acute myeloid leukemia patients treated with transfusions reveal signatures of inflammation and hemostatic dysregulation2024Eva R. Smit, Diana Muñoz Sandoval, Iris C. Kreft, Pieter F. van der Meer, Carmen van der Zwaan, Jan Voorberg, Paula F. Ypma, Arie J. Hoogendijk, Jean-Louis Kerkhoffs & Maartje van den BiggelaarDepartment of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

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Optimization of Mass Spectrometry-Based Methods for Low-Input and Spatial Proteomics2024Andikan Jones NwosuDepartment of Chemistry and Biochemistry, Brigham Young University

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LETMD1 regulates mitochondrial protein synthesis and import to guard brown fat mitochondrial integrity and function2024Madigan Snyder, Yi-Kai Liu, Renjie Shang, Haowei Xu, Charlie Thrift, Xiyue Chen, Jingjuan Chen, Kun Ho Kim, Jiamin Qiu, Pengpeng Bi, W. Andy Tao, Shihuan KuangDepartment of Animal Sciences, Purdue University, West Lafayette, IN, USA

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Tandem mass tag-based proteomic analysis of granulosa and theca interna cells of the porcine ovarian follicle following in vitro treatment with vitamin D3 and insulin alone or in combination2024Kinga Kamińska, Bianka Świderska, Agata Malinowska, Małgorzata GrzesiakDepartment of Endocrinology, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Krakow, Poland

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A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria2024Pablo Hernansanz-Agustín, Carmen Morales-Vidal, Enrique Calvo, Paolo Natale, Yolanda Martí-Mateos, Sara Natalia Jaroszewicz, José Luis Cabrera-Alarcón, Rebeca Acín-Pérez, Iván López-Montero, Jesús Vázquez, José Antonio EnríquezCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain

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High resolution analysis of proteolytic substrate processing2024Jasmin Schillinger, Michelle Koci, Kenny Bravo-Rodriguez, Geronimo Heilmann, Farnusch Kaschani, Markus Kaiser, Christine Beuck, Hartmut Luecke, Robert Huber, Doris Hellerschmied, Steven G. Burston, Michael EhrmannCenter of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany

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mTOR activity paces human blastocyst stage developmental progression2024Maria Novatchkova, Afshan McCarthy, Teresa Rayon, Claire S. Simon, Ilona Dunkel, Sissy E. Wamaitha, Kay Elder, Phil Snell, Leila Christie, Edda G. Schulz, Kathy K. Niakan, Nicolas Rivron, Aydan Bulut-KarslioğluStem Cell Chromatin Group, Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany

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A Multiomics Evaluation of the Countermeasure Influence of 4-Week Cranberry Beverage Supplementation on Exercise-Induced Changes in Innate Immunity2024David C. Nieman, Camila A. Sakaguchi, James C. Williams, Jongmin Woo, Ashraf M. Omar, Fayaj A. Mulani, Qibin Zhang, Wimal Pathmasiri, Blake R. Rushing, Susan McRitchie, Susan J. Sumner, Jackie Lawson and Kevin C. LambirthHuman Performance Laboratory, Appalachian State University, North Carolina Research Campus (NCRC), Kannapolis, NC, USA

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Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy2024Sharon Grisaru-Tal, Valentina Zemser-Werner, Ronen Brenner, Hananya Vaknine, Eran Nizri, Lilach Moyal, Iris Amitay-Laish, Luiza Rosemberg, Ariel Munitz, Noga Kronfeld-Schor, Eric Shifrut, Oren Kobiler, Asaf Madi, Tamar Geiger, Yaron Carmi & Carmit LevyDepartment of Human Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Combined assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human fallopian tube2024Joanna Bons, Isha Bhorkar, Triya Roy, David Schell, Vasco Queiroga, Kehan Ren, Donald Kramer, Wilson Huang, Gabriella C. Russo, Meng-Horng Lee, Pei-Hsun Wu, Ie-Ming Shih, Tian-Li Wang, Mark A. Atkinson, Birgit Schilling, Ashley L. Kiemen, and Denis WirtzJohns Hopkins Institute for Nanobiotechnology, The Johns Hopkins University, Baltimore, MD, USA

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Multi-Omics Revealed Regulatory Mechanisms Underlying the Flowering of Ferula sinkiangensis across Three Dimensions2024Congzhao Fan, Yanfei Li, Jizhao Zhang, Yaqin Zhao, Yigong Zhang, Jun Zhu, Xingwang Gao, Yan Liang, Yuanjin Qiu, Jingyuan Song, and Guoping WangKey Laboratory of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People’s Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College,

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Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis2024Viktória Szentgyörgyi, Leon Maximilian Lueck, Daan Overwijn , Danilo Ritz, Nadja Zoeller , Alexander Schmidt, Maria Hondele , Anne Spang , Shahrzad BakhtiarBiozentrum, University of Basel, Basel, Switzerland

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Chlorin e6-Loaded Nanostructured Lipid Carriers Targeted by Angiopep-2: Advancing Photodynamic Therapy in Glioblastoma2024Carlotta Pucci, Daniele De Pasquale, Andrea Degl'Innocenti, Margherita Montorsi, Andrea Desii, Marta Pero, Chiara Martinelli, Martina Bartolucci, Andrea Petretto, Gianni CiofaniIstituto Italiano di Tecnologia, Smart Bio-Interfaces, Viale Rinaldo Piaggio 34, Pontedera, Italy

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Automated High-Throughput Biological Sex Identification from Archeological Human Dental Enamel Using Targeted Proteomics2024Gaudry B. Troché, Nuno Vibe Hermann, Marina Martínez de Pinillos, María Martinón-Torres, Sandra Mularczyk, Marie Louise Schjellerup Jørkov, Christopher Gerner, Fabian Kanz, Ana Martinez-Val, Enrico Cappellini , Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences , 4321 University of Copenhagen, Denmark

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Exercise-Induced Proteomic Profile Changes in Patients with Advanced Heart Failure2024Anna Drohomirecka,Joanna Waś, Ewa Sitkiewicz, Bianka Świderska, Anna Lutyńska, Tomasz Rywik and Tomasz ZielińskiDepartment of Heart Failure and Transplantation, National Institute of Cardiology, Warsaw, Poland

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CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors2024Haiyan Wang,Paul Westwood, Andreas Topp, Patricia M. Gomez Barila, Jan Paul Medema, Connie R. Jimenez, Bigna Woersdoerfer,3 Stephan Kirchner,3 8 Jitao, David Zhang, Uwe Grether, Arne C. Rufer, Mario van der SteltDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University & Oncode Institute, Leiden, Netherlands

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A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastoma2024Stephanie Maher, Kieran Wynne, Vadim Zhernovkov & Melinda HalaszSystems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland

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De novo protein sequencing of antibodies for identification of neutralizing antibodies in human plasma post SARS-CoV-2 vaccination2024Thierry Le Bihan, Teresa Nunez de Villavicencio Diaz, Chelsea Reitzel, Victoria Lange, Minyoung Park, Emma Beadle, Lin Wu, Marko Jovic, Rosalin M. Dubois, Amber L. Couzens, Jin Duan, Xiaobing Han, Qixin Liu & Bin MaRapid Novor, Inc., Kitchener, ON, Canada,

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Deep Proteome Analysis of Cerebrospinal Fluid from Pediatric Patients with Central Nervous System Cancer2024Christian Mirian, Ole Østergaard, Maria Thastrup, Signe Modvig, Jon Foss-Skiftesvik ,Jane Skjøth-Rasmussen, Marianne Berntsen, Josefine Britze, Alex Christian Yde Nielsen, René Mathiasen, Kjeld Schmiegelow, Jesper Velgaard OlsenNovo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, ,

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100-spd 30-spd 60-spdthermo-orbitrap-exploris-480
1 Annulate Lamellae biogenesis is essential for nuclear pore function2024Junyan Lin, Arantxa Agote-Arán, Yongrong Liao, Rafael Schoch, Paolo Ronchi, Victor Cochard, Rui Zhu, Charlotte Kleiss1,2,3,4, Marc Ruff1,2,3,4,6 3 , Guillaume Chevreux, Yannick Schwab, Bruno P. Klaholz and Izabela SumaraInstitute of Genetics and Molecular and Cellular Biology (IGBMC), Illkirch, France

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A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N labeled proteins2024Maria Wahle, Philip M. Remes, Vincent Albrecht, Johannes Mueller-Reif, Sophia Steigerwald,Tim Heymann, Lili Niu, Philip Lössl, Stevan Horning, Cristina C. Jacob, Matthias MannDepartment for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany,

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Daphnia stress response to environmental concentrations of chloramphenicol—multi-omics approach2024Malgorzata Grzesiuk, Marta Grabska, Agata Malinowska, Bianka Świderska, Elzbieta Grzesiuk, Damian Garbicz & Adrian GoreckiDepartment of Biochemistry and Microbiology, Institute of Biology; Warsaw, University of Life Sciences (SGGW), Warsaw, Poland

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Optimizing proximity proteomics on the EvoSep-timsTOF LC-MS system2024Julia Kitaygorodsky, Brendon Seale, Reuben Samson, Martina Tersigni, Zhen-Yuan Lin, Cassandra Wong, Vesal Kasmaeifar, Anne-Claude GingrasLunenfeld-Tanenbaum Research Institute

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Rapid Tear Proteomics via In-Capillary Digestion for Biomarker Discovery2024James Xiao , Kyla T Frenia , Kathleen C Garwood , Jeremy Kimmel , Leanne T LabriolaRetina Department, Sewickley Eye Group, Sewickley, PA, USA,

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A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage2024James Barrett, Mihris I. S. Naduthodi, Yuwei Mao, Clément Dégut, Sabina Musiał, Aidan Salter, Mark C. Leake, Michael J. Plevin, Alistair J. McCormick, James N. Blaza & Luke C. M. MackinderCentre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK

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Annulate Lamellae biogenesis is essential for nuclear pore function2024Junyan Lin, Arantxa Agote-Arán, Yongrong Liao, Rafael Schoch, Paolo Ronchi, Victor Cochard, Rui Zhu, Charlotte Kleiss, Marc Ruff, GuillaumeChevreux, Yannick Schwab, Bruno P. Klaholz and Izabela SumaraInstitute of Genetics and Molecular and Cellular Biology (IGBMC), Illkirch, France

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A temporal (phospho-)proteomic dataset of neurotrophic receptor tyrosine kinase signalling in neuroblastoma2024Stephanie Maher, Kieran Wynne, Vadim Zhernovkov & Melinda HalaszSystems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland

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Probing SARS-CoV-2 Spike Protein Receptor Binding Domain Dynamics via Hydroxyl Radical Protein Footprinting2024Kezia M. JemisonUniversity of California San Diego

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Longitudinal Assessment of Nasopharyngeal Biomarkers Post-COVID-19: Unveiling Persistent Markers and Severity Correlations2024Mario Durán-Prado, Soledad Illescas, Eduardo Chicano-Galvez, Francisco Javier Gómez-Romero, José Martinez-Alarcón, Javier Arias-Pardilla, Pilar Lopez-Juarez, Juan Fernando Padin, Juan Ramón Peinado, Leticia Serrano-OviedoTraslational Investigation Unit, University General Hospital, SESCAM. Research Institute of Castilla-La Mancha (IDISCAM), Spain

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Rivaroxaban in combination with low-dose aspirin is associated with a reduction in pro-inflammatory and pro-thrombotic circulating vesicle signatures in patients with cardiovascular disease2024Luisa Weiss, Aideen O’Doherty, Wido Uhrig, Paulina B. Szklanna, Molly Hong-Minh, Kieran Wynne, Alfonso Blanco, Jan Zivny, Valeria Lima Passos, Barry Kevane, Seán Murphy, Fionnuala Ní Áinle, Martin O’Donnell, Patricia B. MaguireUCD Conway SPHERE Research Group, Conway Institute, University College Dublin, Dublin, Ireland

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Spatial proteomics identifies JAKi as treatment for a lethal skin disease2024Florian Anzengruber, Maximilian T. Strauss, Maria C. Tanzer, Yuki Saito, Ting Gong, Marvin Thielert, Haruna Kimura, Natasha Silke, Edwin H. Rodriguez, Gaetana Restivo, Hong Ha Nguyen, Annette Gross, Laurence Feldmeyer, Matthias MannDepartment of Proteomics and Signal Transduction; Max Planck Institute of Biochemistry, Martinsried, Germany

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Streamlined analysis of drug targets by proteome integral solubility alteration indicates organ-specific engagement2024Tanveer Singh Batth, Marie Locard-Paulet, Nadezhda T. Doncheva, Blanca Lopez Mendez, Lars Juhl Jensen & Jesper Velgaard OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark,

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Unveiling the critical role of androgen receptor signaling in avian sexual development2024Kamila Lengyel, Mekhla Rudra, Tom V. L. Berghof, Albertine Leitão, Carolina Frankl-Vilches, Falk Dittrich, Denise Duda, Romina Klinger, Sabrina Schleibinger, Hicham Sid, Lisa Trost, Hanna Vikkula, Benjamin Schusser & Manfred GahrDepartment of Behavioural Neurobiology, Max Planck Institute for Biological Intelligence, Seewiesen, Germany

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Proteomics dataset of lysolecithin-induced demyelinated lesions in corpus callosum of Lewis rats, treated with Vagus Nerve Stimulation or sham treatment2024Helen Bachmann, Boris Vandemoortele, Vanessa Vermeirssen, Evelien Carrette, Kristl Vonck, Paul Boon, Robrecht Raedt, Guy Laureys4Brain, Department of Neurology, Ghent University, Ghent University Hospital, Corneel Heymanslaan 10, Ghent, Belgium

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P-stalk ribosomes act as master regulators of cytokine-mediated processes2024Mandy Kerkhoff, Anastasia Gangaev, Joana Silva, Sofia Ramalho, Liesbeth Hoekman, Maarten Altelaar, Roderick Beijersbergen, Leila Akkari, Jonathan Wilson Yewdel, Pia Kvistborg, William James FallerDivision of Oncogenomics, Netherlands Cancer Institute, Amsterdam, the Netherlands

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High-throughput and high-sensitivity biomarker monitoring in body fluid by fast LC SureQuant™ IS targeted quantitation2024Konstantinos Kalogeropoulos, Simonas Savickas, Aleksander M. Haack, Cathrine A. Larsen, Jacek Mikosiński, Erwin M. Schoof, Hans Smola, Louise Bundgaard, Ulrich auf dem KellerDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Kgs. Lyngby, Denmark,

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100-spd 60-spdthermo-orbitrap-exploris-480
Integrative phosphoproteomic analysis reveal hemostatic-endothelial signaling interplay Integrative phosphoproteomic analysis reveal hemostatic-endothelial signaling interplay2024Stijn A. Groten, Bart L. van den Eshof, Floris P.J. van Alphen, Alexander B. Meijer, Maartje van den Biggelaar , Arie J. HoogendijkDepartment of Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

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Cytoprotective Effects of Antioxidant Peptides from Red Californian Worm (Eisenia foetida) Hydrolysate on Differentiated Caco-2 Cells2024Yhoan S. Gaviria, José E. Zapata, Diego Miedes, Amparo Alegría and Antonio CillaNutrition and Food Science Area, Faculty of Pharmacy and Food Sciences, University of Valencia, Avda. Vicente Andrés Estellés s/n, Burjassot, Valencia, Spain

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Effect of ultrasound and enzymatic pre-treatments on the profile of bioactive peptides of beef liver hydrolysates2024Marta Gallego, Leticia Mora, Fidel ToldráInstituto de Agroquímica y Tecnología de Alimentos (CSIC), Paterna, Valencia, Spain

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Using in vivo intact structure for system-wide quantitative analysis of changes in proteins2024Ahrum Son, Hyunsoo Kim, Jolene K. Diedrich, Casimir Bamberger, Daniel B. McClatchy, Stuart A. Lipton & John R. Yates IIIDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA

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Combining ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma2024Marco Scarsella, Gabriele Volpe, Marco Pezzullo, Cristiano De Stefanis, Valentina D’Oria, Lorenzo De Angelis, Roberto Giovannoni, Maria Antonietta De Ioris, Ombretta Melaiu, Anthony W. Purcell, Franco Locatelli & Doriana FruciBambino Gesù Children’s Hospital, IRCCS, Rome, Italy

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Developing a Soft Micropatterned Substrate to Enhance Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes2024Yasaman Maaref, Shayan Jannati, Farah Jayousi, Philipp Lange, Mohsen Akbari, Mu Chiao, Glen F TibbitsCellular and Regenerative Medicine Centre, BC Children's Hospital Research Institute, Vancouver, BC, Canada

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Characterization of the Peroxisomal Proteome and Redox Balance in Human Prostate Cancer Cell Lines2024Mohamed A. F. Hussein, Celien Lismont, Cláudio F. Costa, Hongli Li,Frank Claessens and Marc FransenLaboratory of Peroxisome Biology and Intracellular Communication, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise2024Birgitte Hoier, Camilla C. Hansen, Thomas E. Jensen, Ylva Hellsten, Henriette Pilegaard, Niels Grarup, Jesper Olesen, Sean J. Humphrey, David E. James, Michael L. Pedersen, Erik A. Richter, Torben Hansen, Marit E. Jørgensen & Jørgen F. P. WojtaszewskiAugust Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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High-Throughput Chromatography for Clinical Proteomics Applications2024Goran Mitulović and Jadranka Miletić VukajlovićBruker Austria, Vienna, Austria

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The proteomic landscape of proteotoxic stress in a fibrogenic liver disease2024Maximilian Zwiebel, Niklas A. Schmacke, Sonke Detlefsen, Peter Boor, Joseph Kaserman, Andrew Wilson, Ondrej Fabian, Sona Frankova, Aleksander A. Krag, Pavel Strnad, and Matthias MannDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism2024Ivan Bradić, Katharina B. Kuentzel, Anita Pirchheim, Silvia Rainer, Birgit Schwarz, Michael Trauner, Martin R. Larsen, Nemanja Vujić, Dagmar KratkyGottfried Schatz Research Center, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria

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Single-Cell Proteomic and Transcriptomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes2024Jongmin Woo, Michael Loycano, Md Amanullah, Jiang Qian, Sarah Amend, Kenneth Pienta, Hui ZhangCancer Ecology Center, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231

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High throughput single-cell proteomics of in-vivo cells2024Shiri Karagach, Joachim Smollich, Ofir Atrakchi, Vishnu Mohan, and Tamar GeigerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

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Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint2024Daniel Blears, Jiangman Lou, Nova Fong, Richard Mitter, Ryan M. Sheridan, Dandan He, A. Barbara Dirac-Svejstrup, David Bentley, Jesper Q. SvejstrupDepartment of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, Copenhagen, Denmark

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Small molecule modulation of protein corona for deep plasma proteome profiling2024Ghafar Yerima, Ali Tamadon, Maryam Sayadi, Maryam Jafari, Zijin Lin, Danilo Ritz, David Kakhniashvili, Avirup Guha, Mohammad R. K. Mofrad, Liangliang Sun, Markita P. Landry, Amir Ata Saei & Morteza MahmoudiPrecision Health Program, Michigan State University, East Lansing, MI, USA

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30-spdthermo-orbitrap-astral
Robust high throughput peptide quantitation using scout triggered MRM on the Triple Quad 7500 system2024J.C. Yves Le Blanc, Jenny Albanese, Holly Lee, David M. Cox, and Patrick PribilSCIEX Canada, , , ,

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100-spd 200-spd 300-spd 500-spd 60-spdsciex-triple-quad-7500
Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis2024Daniel Stephenson, Marta Suarez Cubero, Sandra Rizzi, Liviu Pirvan, Luca Peruzzotti-Jametti, Valentina Fossati, Frank Edenhofer, Tommaso Leonardi, Christian Frezza, Irina Mohorianu, Angelo D’Alessandro, Stefano PluchinoDepartment of Clinical Neurosciences and NIHR Biomedical Research Centre, University of Cambridge, Cambridge CB2 0AH, UK

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30-spdbruker-timstof-pro
Proteomic and metabolomic profiles of plasma-derived Extracellular Vesicles differentiate melanoma patients from healthy controls2024SM Bollard, J Howard, C Casalou, BS Kelly, K O’Donnell, G Fenn, J O’Reilly, R Milling, M Shields, M Wilson, A Ajaykumar, K Triana, K Wynne, DJ Tobin, PA Kelly,A McCann, SM PotterDepartment of Plastic & Reconstructive Surgery, Mater Misericordiae University Hospital, Dublin, Ireland

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HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status2024Marc E. Healy, Amiskwia Pöschel, Enni Markkanen, Nasser Semmo, Martin Ferrié, Laurence Cocquerel, Harald Seeger, Helmut Hopfer, Beat Müllhaupt, Jérôme Gouttenoire, Darius Moradpour, Ariana Gaspert & Achim WeberDepartment of Pathology and Molecular Pathology, University of Zurich (UZH) and University Hospital Zurich (USZ), Zurich, Switzerland,

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bruker-timstof-pro thermo-orbitrap-astral
B-246 Pab to mab conversion via mass spectrometry: direct antibody discovery from serum2024J Crha, X Han, T Le Bihan, T Nunez De Villavicencio Diaz, B MaRapid Novor, Inc., Kitchener, ON, Canada

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The MON1–CCZ1 complex plays dual roles in autophagic degradation and vacuolar protein transport in rice2024Yongfei Wang, Pengcheng Zhang, Yu Chen, Erchao Duan, Xiaohang Han, Gexing Wan, Mengyuan Yan, Xiejun Sun, Cailin Lei, Zhijun Cheng, Zhichao Zhao, Ling Jiang, Yiqun Bao, Yulong Ren and Jianmin WanState Key Laboratory of Crop Gene Resources and Breeding, National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China

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A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax52024Joan Josep Bech, Thomas Braun, Alessandro Ianni, Jay A. Tischfield, Lourdes Serrano, Manel Esteller, Jose L. Sardina, Carolina De La Torre, Mikael Sigvardsson, Berta N. Vazquez & Alejandro VaqueroChromatin Biology Laboratory, Josep Carreras Leukemia Research Institute, Badalona, Spain

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15-spd
Characterization of psychrotrophic and thermoduric bacteria in raw milk using a multi-omics approach2024Xue Qin, Jingqi Cheng​, Yue Qiu​, Ning Guan​, Tanushree B. Gupta​, Shuyan Wu​, Yujun Jiang​, Xinyan Yang​ and Chaoxin ManKey Laboratory of Dairy Science, Ministry of Education, College of Food Science and Engineering, Northeast Agricultural University, Harbin, PR China

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Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification2024Mujia Jenny Li, Larissa Chiara Meyer, Nadine Meier, Jannik Witte, Maximilian Maldacker, Adrianna Seredynska, Julia Schueler, Oliver Schilling, Melanie Christine FöllInstitute for Surgical Pathology, Faculty of Medicine, University Medical Centre Freiburg, University of Freiburg, Freiburg, Germany

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30-spdbruker-timstof-flex
Mass spectrometry–based proteomic exploration of diverse murine macrophage cellular models2024Jack Gudgeon, Abeer Dannoura, Ritika Chatterjee, Frances Sidgwick, Benjamin BA Raymond, Andrew M Frey, Jose Luis Marin-Rubio, Matthias TrostNewcastle University: Newcastle upon Tyne, Newcastle upon Tyne, GB

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High-Throughput Tear Proteomics via In-Capillary Digestion for Biomarker Discovery2024James Xiao, Kyla Frenia, Kathleen C. Garwood,Jeremy Kimmel and Leanne T. LabriolaRetina Department, Sewickley Eye Group, Sewickley, PA, USA

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Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases2024Maria Chernigovskaya, Khang Lê Quý, Maria Stensland, Sachin Singh, Rowan Nelson, Melih Yilmaz, Konstantinos Kalogeropoulos, Pavel Sinitcyn, Anand Pate, Natalie Castellana, Stefano Bonissone, Stian Foss, Jan Terje Andersen, Geir Kjetil Sandve, Timothy PatrDepartment of Immunology, University of Oslo and Oslo University Hospital, Norway

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20-spdthermo-q-exactive-hf
Towards routine proteome profiling of FFPE tissue: insights from a 1,220-case pan-cancer study2024Johanna Tüshaus, Marius Schliemann, Yuxiang Zhou, Pauline Pfeiffer, Christiane Halves, Federico Fusco, Johannes Weigel, Lisa Hönikl, Vicki Butenschön, Rumyana Todorova, Hilka Rauert-Wunderlich, Matthew The, Andreas Rosenwald, Volker Heinemann, Julian HolcProteomics and Bioanalytics, School of Life SciencesTechnical University of Munich Freising Germany

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Anubis: a multi-level authentication scale for ancient proteins using random forest classification2024Yun Chiang, Bharath Anila Bhuvanendran Nair, Max Emil Ermter Ramsøe, Tina Ravnsborg, Ole Nørregaard Jensen & Matthew James CollinsGlobe Institute, University of Copenhagen, Copenhagen, Denmark

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60-spdthermo-q-exactive-hf
Identification and Characterization of Spontaneous AA Amyloidosis in CD-1 Mice Used in Toxicity2024Mao Mizukawa, Kohei Tanaka, Akane Kashimura, Yu Uchida, Takanori Shiga, Naoyuki Aihara, and Junichi KamieLaboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa, Japan

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30-spdthermo-q-exactive
Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model2024Neža Cankar, Natalie Beschorner, Anastasia Tsopanidou, Filippa L. Qvist, Ana R. Colaço, Mie Andersen, Celia Kjaerby∙ Christine Delle, Marius Lambert, Filip Mundt, Pia Weikop, Mathias Jucker, Matthias Mann, Niels Henning Skotte, Maiken NedergaardCenter for Translational Neuromedicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen N, Denmark

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Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease2024Sumi Bez, Elena Ficulle, Eliona Tsefou, Roman Fischer, Beth Geary, Pallavi Gaur, Chelsea Miller, Pasquale D’Acunzo, Efrat Levy, Karen E. Duff & Benjamin Ryskeldi-FalconMedical Research Council Laboratory of Molecular Biology, Cambridge, UK

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Data-independent acquisition-based blood proteomics unveils predictive biomarkers for neonatal necrotizing enterocolitis2024Feng Chen, Kezhe Tan, Zhibao Lv, Faling Chen, Weijue Xu, Xiaohui Gong, Li Lu, Hailiang Sun, Qinqin Fu & Wenjun ZhuangDepartment of General Surgery, Affiliated Changzhou Children’s Hospital of Nantong University, Jiangsu, China

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30-spdthermo-q-exactive-hf
Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training2024Juha J. Hulmi, Eeli J. Halonen, Adam P. Sharples, Thomas M. O'Connell, Lauri Kuikka L, VeliMatti Lappi, Kari Salokas, Salla Keskitalo, Markku Varjosalo, Juha P. AhtiainenFaculty of Sport and Health Sciences, Neuromuscular Research Center, University of Jyväskylä,Finland

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60-spdtimstof-pro-2
Optimization of a Digestion Protocol for Proteomic Profiling of Low Cell Number FACS-Sorted Cells2024Kovi Rishya Shrung GovindarajanKTH Royal Institute of Technology, Stockholm, Sweden

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Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway which is dependent on low IGF1R level2024Sarah Hyllekvist Jørgensen, Kristina Bennet Emdal, Anna-Kathrine Pedersen, Lene Nygaard Axelsen, Helene Faustrup Kildegaard, Damien Demozay, Thomas Åskov Pedersen, Mads Grønborg, Rita Slaaby, Peter Kresten Nielsen & Jesper Velgaard OlsenProteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,

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30-spd 60-spdthermo-orbitrap-exploris-480
A compendium of bona fide reference markers of plant-derived extracellular vesicles and their degree of phylogenetic conservation2024Rodríguez de Lope, Miriam M. Sánchez-Pajares, Ibone R. Herranz, Estela López Vázquez, Cristina M. González-Moro, Ainara Rivera-Tenorio, Alan González-Sanz Carlos, Soledad Sacristán, Chicano-Gálvez, Eduardo de la Cuesta, FernandoDepartment of Pharmacology, School of Medicine, Universidad Autónoma de Madrid, Spain

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The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium2024Olivia Charmant, Julita Gruchota, Olivier Arnaiz, Katarzyna P Nowak, Nicolas Moisan, Coralie Zangarelli, Mireille Bétermier, Anna Anielska-Mazur, Véronique Legros, Guillaume Chevreux, Jacek K Nowak, Sandra DuharcourtUniversité Paris Cité, CNRS, Institut Jacques Monod, Paris, France

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Porin expression in clinical isolates of Klebsiella pneumoniae: a comparison of SDS-PAGE and MALDI-TOF/MS and limitations of whole genome sequencing analysis2024Cristina Elías-López, Montserrat Muñoz-Rosa, Julia Guzmán-Puche, Elena Pérez-Nadales, Eduardo Chicano-Galvez & Luis Martínez-MartínezReina Sofía University Hospital, Maimonides Biomedical Research Institute of Cordoba, University of Cordoba (IMIBIC/HURS/UCO), Cordoba, Spain

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A Recombinant Shigella flexneri Strain Expressing ETEC Heat-Labile Enterotoxin B Subunit Shows Promise for Vaccine Development via OMVs2024Josune Salvador-Erro, Yadira Pastor, and Carlos GamazoDepartment of Microbiology and Parasitology, Navarra Medical Research Institute (IdiSNA), University of Navarra, Pamplona, Spain

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Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer2024Adva Kochavi, Remco Nagel, Pierre-Rene Körner, Onno B Bleijerveld, Chun-Pu Lin, Zowi Huinen, Yuval Malka, Natalie Proost, Marieke van de Ven, Xiaodong Feng, Jasmine Montenegro Navarro, Abhijeet Pataskar, Daniel S Peeper, Julien Champagne, Reuven AgamiDivision of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands

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Human VCP mutant ALS/FTD microglia display immune and lysosomal phenotypes independently of GPNMB2024Benjamin E. Clarke, Oliver J. Ziff, Giulia Tyzack, Marija Petrić Howe, Yiran Wang, Pierre Klein, Claudia A. Smith, Cameron A. Hall, Adel Helmy, Michael Howell, Gavin Kelly & Rickie PataniDepartment of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, UK

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A novel process for transcellular hemoglobin transport from macrophages to cancer cells2024Jaroslaw Walczak, Lukasz Cheda, Michal Komorowski, Tobias Weiss, Małgorzata Czystowska-Kuzmicz, Karina Kwapiszewska, Alberto Boffi, Magdalena Krol & Tomasz P. RygielDepartment of Immunology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland

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Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation2024Legros Véronique, Albanese Véronique, Chevreux Guillaume, Camadro Jean-Michel & Auchère FrançoiseUniversité Paris Cité, CNRS, Institut Jacques Monod, Paris, France

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Raphe and ventrolateral medulla proteomics in sudden unexplained death in childhood with febrile seizure history2024Dominique F. Leitner, Christopher William, Arline Faustin, Evgeny Kanshin, Matija Snuderl, Declan McGuone, Thomas Wisniewski, Beatrix Ueberheide, Laura Gould & Orrin DevinskyComprehensive Epilepsy Center, NYU Grossman School of Medicine, New York, NY, USA

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Chemogenomic Screeningina Patient-Derived 3DFatty Liver Disease Model Reveals the CHRM1-TRPM8 Axisasa Novel Module for Targeted Intervention2024Brinton Seashore-Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, and Volker M. LauschkeHepaPredict AB, Stockholm, Sweden

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Nuclear Factor I family members are key transcription factors regulating gene expression2024Dicle Malaymar Pinar, Helka Göös, Zenglai Tan, Esa-Pekka Kumpula, Iftekhar Chowdhury, Zixian Wang, Qin Zhang, Kari Salokas, Salla Keskitalo, Gong-Hong Wei, Asli Kumbasar, Markku VarjosaloInstitute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland

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Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction2024Dragana Vukić, Anna Cherian, Salla Keskitalo, Yih Tyng Bong, Martin Marônek, Leena Yadav, Liam P Keegan, Markku Varjosalo, Mary A O’ConnellCentral European Institute of Technology (CEITEC), Masaryk University, Kamenice 5, Brno, Czechia,

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Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport2024D. Bizzarri, E.B. van den Akker, M.J.T. Reinders, R. Pool, M. Beekman, N. Lakenberg, N. Drouin, K.E. Stecker, A.J.R. Heck, E.F. Knol, J.M. Vergeer, M.A. Ikram, M. Ghanbari, A.J. van Gool11, BBMRI-NL, D.I. Boomsma, and P.E. SlagboomDepartment of Biomedical Data Sciences, Molecular Epidemiology, LUMC, Leiden, The Netherlands

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Isobaric labeling update in MaxQuant2024Daniela Ferretti, Pelagia Kyriakido, Jinqiu Xiao, Shamil Urazbakhtin, Carlo DeNart and Jürgen CoxComputational Systems Biochemistry Research Group, Max Planck Institute of Biochemistry, Martinsried, Germany.,

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CRISPR/Cas9-induced double-strand breaks in the huntingtin locus lead to CAG repeat contraction through DNA end resection and homology-mediated repair2024Pawel Sledzinski, Mateusz Nowaczyk, Marianna Iga Smielowska & Marta OlejniczakDepartment of Genome Engineering, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland

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Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD2024Marcos Fernández-Alfara, Judit Martín, Cesare De Pace, Lorena Ruiz-Pérez, Jesús García, Giuseppe Battaglia, José J. Lucas, Rubén Hervás, Kresten Lindorff-Larsen, Raúl Méndez & Xavier SalvatellaInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain

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Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities2024Lydia Ziane-Chaouche, Antonella Raffo-Romero, Nawale Hajjaji, Firas Kobeissy, Donna Pinheiro, Soulaimane Aboulouard, Adeline Cozzani, Suman Mitra, Isabelle Fournier, Dasa Cizkova, Michel Salzet & Marie DuhamelUniversité Lille, Inserm, CHU Lille, U1192, Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), Villeneuve d’Ascq, France,

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60-spdbruker-timstof-ht thermo-q-exactive
The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base2024Sini Huuskonen, Xiaonan Liu, Ina Pöhner, Taras Redchuk, Kari Salokas, Rickard Lundberg, Sari Maljanen, Milja Belik, Arttu Reinholm, Pekka Kolehmainen, Antti Tuhkala, Garima Tripathi, Pia Laine, Sergei Belanov, Petri Auvinen, Maria Vartiainen, Salla KeskitInstitute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki, Finland

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CCDC134 controls TLR biogenesis through the ER chaperone Gp962024Léa Bernaleau, Michaela Drobek, Fenja Blank, Philipp Walch, Maeva Delacrétaz, Ales Drobek, Marta Monguió-Tortajada, Petr Broz, Olivia Majer, Manuele RebsamenDepartment of Immunobiology, University of Lausanne, Epalinges, Switzerland

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Extracellular Vesicle-Driven Crosstalk between Legume Plants and Rhizobia: The Peribacteroid Space of Symbiosomes as a Protein Trafficking Interface2024Paula Ayala-García, Irene Herrero-Gómez, Irene Jiménez-Guerrero, Viktoria Otto, Natalia Moreno-de Castro, Mathias MüskenLothar Jänsch, Marco van Ham, José-María Vinardell, Francisco Javier López-Baena, Francisco Javier Ollero, Francisco Pérez-Montaño, JosDepartment of Microbiology, Faculty of Biology, Universidad de Sevilla, Sevilla, Spain

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Extracellular vesicles from mesenchymal stem cells improve neuroinflammation and neurotransmission in hippocampus and cognitive impairment in rats with mild liver damage and minimal hepatic encephalopathy2024Gergana Mincheva, Victoria Moreno-Manzano, Vicente Felipo & Marta LlansolaLaboratory of Neurobiology, Centro de Investigación Príncipe Felipe, Valencia, Spain

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5′ terminal nucleotide determines the immunogenicity of IVT RNAs2024Magdalena Wolczyk, Jacek Szymanski, Ivan Trus, Zara Naz, Tola Tame, Agnieszka Bolembach, Nila Roy Choudhury, Karolina Kasztelan, Juri Rappsilber, Andrzej Dziembowski, Gracjan MichlewskiInternational Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland

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Enhancing Digestibility and Intestinal Peptide Release of Pleurotus eryngii Protein: An Enzymatic Approach2024Dandan Wang, Meng Zhang, Jianing Wan, Haiquan Liu, Ying Wang, Ruiheng Yang, Yingying Wu, Dapeng Bao, Hongyu Chen, Gen Zou and Yong ZhaoCollege of Food Sciences and Technology, Shanghai Ocean University, Shanghai, China

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30-spdtimstof-pro-2
Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster2024Najla El Fissi, Florian A. Rosenberger, Kai Chang, Alissa Wilhalm, Tom Barton-Owen, Fynn M. Hansen, Zoe Golder, David Alsina, Anna Wedell, Matthias Mann, Patrick F. Chinnery, Christoph Freyer & Anna WredenbergDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

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Impaired Cerebrospinal Fluid Lipoprotein-Mediated Cholesterol Delivery to Neurons in Alzheimer’s Disease2024Carla Borràs, Marina Canyelles, David Santos, Noemí Rotllan, Estefanía Núñez, Jesús Vázquez, Daniel Maspoch, Mary Cano-Sarabia, Maria Carmona-Iragui, Sònia Sirisi, Alberto Lleó, Juan Fortea, Daniel Alcolea, Francisco Blanco-Vaca, Joan Carles Escolà-Gil,Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

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15-spdthermo-orbitrap-eclipse-tribid
The characterization of outer membrane vesicles (OMVs) and their role in mediating antibiotic-resistance gene transfer through natural transformation in Riemerella anatipestifer2024Mengying Wang, Yizhou Yao, Yuhao Yang, Dekang Zhu, Mingshu Wang, Renyong Jia, Shun Chen, Xinxin Zhao, Qiao Yang , Ying Wu , Shaqiu Zhang, Juan Huang, Xumin Ou, Bin Tian, Di Sun, Ling Zhang, Yanling Yu, Yu He, Zhen Wu, Anchun Cheng, Mafeng LiuEngineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China

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Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine2024Julienne L. Carstens, Mehmet Akce, Cameron Herting, Olatunji B. Alese, Karina J. Yoon, Upender Manne, Manoj K. Bhasin, Gregory B. Lesinski, Vikas P. Sukhatme, Bassel F. El-RayesDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA

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60-spdthermo-q-exactive-plus
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota2024Ana Martínez Gascueña, Isabel García-Álvarez, Jon Ander Nieto-Garai, June Olazar-Intxausti, Bárbara Rodríguez-Colinas, Enrique Mann, José Luis Chiara, Francesc-Xabier Contreras, Marcelo E. Guerin, Beatriz Trastoy & Laura Alonso-SáezAZTI, Marine Research, Basque Research and Technology Alliance (BRTA), Sukarrieta, Spain

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30-spdbruker-timstof-pro
Exploring proteins within the coccolith matrix2024Craig J. Dedman, Nishant Chauhan, Alba González-Lanchas, Chloë Baldreki, Adam A. Dowle, Tony R. Larson, Renee B. Y. Lee & Rosalind E. M. RickabyDepartment of Earth Sciences, University of Oxford, South Parks Rd, Oxford, UK

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Multi-tiered proteome analysis displays the hyper-permeability of the rheumatoid synovial compartment for plasma proteins2024Eva Maria Stork, Sofia Kalaidopoulou Nteak, Danique M.H. van Rijswijck, J. Mirjam A. Damen, Hans Ulrich Scherer, Rene E.M. Toes, Albert Bondt, Tom W.J. Huizinga, Albert J.R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, The Netherlands

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30-spdthermo-orbitrap-exploris-480
Protein aggregation capture assisted profiling of the thiol redox proteome2024Ana Martinez-Val, Samuel Lozano-Juárez, Jorge Lumbreras, Irene Rodríguez, Marinela Couselo-Seijas, Ana Simón-Chica, Carlos Galán-Arriola, Rodrigo Fernández, Estefanía Núñez, Inmaculada Jorge, David Filgueiras-Rama, Borja Ibáñez, Jesús VázquezCardiovascular Proteomics Laboratory, Centro Nacional de Investigaciones, Cardiovasculares Carlos III (CNIC), Madrid, Spain

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15-spdthermo-orbitrap-eclipse-tribid
Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP2024Andrew Leduc, Luke Khoury, Joshua Cantlon, Saad Khan, Nikolai SlavovDepartments of Bioengineering, Biology, Chemistry and Chemical Biology, Single Cell Proteomics Center, and Barnett Institute, Northeastern University, Boston, MA, USA.

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60-spdthermo-orbitrap-exploris-480
Amyloid beta precursor protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)2024Sara Bagnoli, Frauke van Bebber, Lisa Adam, Farzana Shamim-Schulze, Oliver Ohlenschläger, Martin Bens, Emilio Cirri, Adam Antebi, Ivan Matić, Anja Schneider, Bettina Schmid, Alessandro Cellerino, Janine Kirstein, Dario Riccardo ValenzanoLeibniz Institute on Aging – Fritz Lipmann Institute (FLI), Jena, Germany

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30-spdthermo-orbitrap-exploris-480
Free amino acids accelerate the time-dependent inactivation of rat liver nucleotide pyrophosphatase/phosphodiesterase Enpp3 elicited by EDTA2024Ana Romero, Guadalupe Cumplido-Laso, Ascensión Fernández, Javier Moreno, José Canales, Rui Ferreira, Juan López-Gómez, João Meireles Ribeiro, María Jesús Costas & José Carlos CameselleDepartamento de Bioquímica y Biología Molecular y Genética, Facultad de Medicina y Ciencias de la Salud, Universidad de Extremadura, Badajoz, Spain

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30-spdtimstof-pro-2
Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors2024Silvana Bazua-Valenti, Matthew R. Brown, Jason Zavras, Magdalena Riedl Khursigara, Elizabeth Grinkevich, Eriene-Heidi Sidhom, Keith H. Keller, Matthew Racette, Moran Dvela-Levitt, Catarina Quintanova, Hasan Demirci, Sebastian Sewerin, Alissa C. Goss, JohnThe Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, Massachusetts, USA

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thermo-q-exactive-hf
ZenoSWATH proteomics and clustering analysis reveal different modulation patterns in fibroblasts from cystinosis patients by cysteamine2024Ignacio Ortea, Lorena Rodríguez-Martínez, Mónica Carrera, Miguel González-Barcia, Anxo Fernández-Ferreiro, Jesús MateosHuman Proteome Organization World Congress

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60-spdsciex-zenotof-7600
Phosphoproteomics profiling of sorafenib-resistant HCC patient-derived xenografts reveals potential therapeutic strategies2024Feng Li, Bo Hu, Lei Zhang, Yang Liu, Jun Wang, Changqing Wu, Suiyi Wu, Ying Zhang, Xinrong Yang, and Haojie LuLiver Cancer Institute and Institutes of Biomedical Sciences, Zhongshan Hospital, Fudan University, Shanghai, P.R. China

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thermo-orbitrap-exploris-480
Integrated multi-omics profiling reveals neutrophil extracellular traps potentiate Aortic dissection progression2024Yu-Fei Zhao, Zi-Ang Zuo, Zhe-Yun Li, Ye Yuan, Shi-Chai Hong, Wei-Guo Fu, Bin Zhou & Li-Xin WangDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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bruker-timstof-pro
Heterogeneity Assessment and Protein Pathway Prediction via Spatial Lipidomic and Proteomic Correlation: Advancing Dry Proteomics concept for Human Glioblastoma Prognosis2024Laurine Lagache, Yanis Zirem, Émilie Le Rhun, Isabelle Fournier, Michel SalzetUniv.Lille, Inserm, CHU Lille, U1192 – Proteomics Inflammatory Response Mass Spectrometry- PRISM, Lille, France

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Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway2024Hirokazu Yagi, Rino Yamada, Taiki Saito, Rena Honda, Rio Nakano, Kengo Inutsuka, Seigo Tateo, Hideo Kusano, Kumiko Nishimura, Saeko Yanaka, Takuro Tojima, Akihiko Nakano, Jun-ichi Furukawa, Maho Yagi-Utsumi, Shungo Adachi, Koichi KatoFaculty and Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan

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thermo-q-exactive-hf
Robust dimethyl-based multiplex-DIA workflow doubles single-cell proteome depth via a reference channel2023Marvin Thielert, Corazon Ericka Mae Itang, Constantin Ammar, Florian A Schober, Isabell Bludau, Patricia Skowronek, Maria Wahle, Wen-Feng Zeng, Xie-Xuan Zhou, Andreas-David Brunner, Sabrina Richter, Fabian J Theis, Martin Steger, Matthias MannMax Planck Institute of Biochemistry, Boehringer Ingelheim Pharma GmbH & Co, German Research Center for Environmental Health, Technical University of Munich, NEOsphere Biotechnologies GmbH, University of Copenhagen

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Comparative proteome and transcriptome analyses of the response of postharvest pears to Penicillium expansum infection2023Meiqiu Xu, Esa Abiso Godana, Solairaj Dhanasekaran, Xiaoyun Zhang, Qiya Yang, Lina Zhao and Hongyin ZhangJiangsu University, Luoyang Normal University

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timstof-pro-2
Recent advances in the field of single-cell proteomics2023Valdemaras Petrosius and Erwin M. SchoofTechnical University of Denmark,

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whisper-20spd whisper-40spd
Differential proteomic profile of lumbar and ventricular cerebrospinal fluid2023Nina Rostgaard, Markus Harboe Olsen, Maud Ottenheijm, Lylia Drici, Anja Hviid Simonsen, Peter Plomgaard, Hanne Gredal, Helle Harding Poulsen, Henrik Zetterberg, Kaj Blennow, Steen Gregers Hasselbalch, Nanna MacAulay, Marianne JuhlerCopenhagen University Hospital, University of Copenhagen, University of Gothenburg,

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60-spdthermo-orbitrap-exploris-480
Identification of Highly Sensitive Pleural Effusion Protein Biomarkers for Malignant Pleural Mesothelioma by Affinity-Based Quantitative Proteomics2023Nicolai B. Palstrøm, Martin Overgaard, Peter Licht , Hans C. BeckOdense University Hospital, University of Southern Denmark,

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60-spdthermo-altis-triple-quadrupole
PRMT5-mediated regulatory arginine methylation of RIPK32023Chanchal Chauhan, Ana Martinez-Val, Rainer Niedenthal, Jesper Velgaard Olsen, Alexey Kotlyarov, Simon Bekker-Jensen, Matthias Gaestel & Manoj B. MenonHannover Medical School, University of Copenhagen, Indian Institute of Technology Delhi

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60-spdthermo-orbitrap-exploris-480
Quantitative multi-organ proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation2023Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes B. Müller-Reif, Wen-Feng Zeng, Sebastian Dintner, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias MannMax-Planck Institute of Biochemistry, University Medical Center Augsburg,

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30-spdthermo-orbitrap-exploris-480
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer2023Antonela Merlotti, Benjamin Sadacca, Yago A. Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira,Université Paris Sciences et Lettres, Laboratory of Clinical immunology, Institute Mutualiste Montsouris, Dana-Farber Cancer Institute, Institut d’Investigacions Biomèdiques de Barcelona-CSIC, Dana-Farber Cancer Institute

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thermo-q-exactive
Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling2023Laurent Lignieres, Nicolas Sénécaut, Tien Dang, Laura Bellutti, Marion Hamon, Samuel Terrier, Véronique Legros, Guillaume Chevreux, Gaëlle Lelandais, René-Marc Mege, Julien Dumont, and Jean-Michel CamadroUniversité Paris Cité, Institut de Biologie Physico-Chimique, Institut de Biologie Physico-Chimique Véronique Legros, Guillaume Chevreux, Gaëlle Lelandais, René-Marc Mege, ̀ Julien Dumont,Institut de Biologie Physico-Chimique, Institut de Biologie Intégra

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30-spdthermo-orbitrap-fusion
Unique DUOX2+ACE2+ small cholangiocytes are pathogenic targets for primary biliary cholangitis2023Xi Li, Yan Li, Jintao Xiao, Huiwen Wang, Yan Guo, Xiuru Mao, Pan Shi, Yanliang Hou, Xiaoxun Zhang, Nan Zhao, Minghua Zheng, Yonghong He, Jingjing Ding, Ya Tan, Min Liao, Ling Li, Ying Peng, Xuan Li, Qiong Pan, Qiaoling Xie, Qiao Li, Jianwei Li, Ying Li, ZDaping Hospital, Xiangya Hospital, Central South University, the First Affiliated Hospital of Wenzhou Medical University, ale University School of Medicine,

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bruker-timstof
β-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited2023Si Liu, Tanja Narancic, Jia‑Lynn Tham & Kevin E. O’ConnorUniversity College Dublin

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30-spdtimstof-pro
Exploiting Multi-Omics Profiling and Systems Biology to Investigate Functions of TOMM342023Ekaterina V. Poverennaya, Mikhail A. Pyatnitskiy, Georgii V. Dolgalev, Viktoria A. Arzumanian, Olga I. Kiseleva, Ilya Yu. Kurbatov, Leonid K. Kurbatov, Igor V. Vakhrushev, Daniil D. Romashin, Yan S. Kim and Elena A. PonomarenkoInstitute of Biomedical Chemistry Moscow & Faculty Of Computer Science & National Research University Higher School of Economics Moscow

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30-spdthermo-q-exactive
BRM Complex in Arabidopsis Adopts ncBAF-like Composition and Requires BRD Subunits for Assembly and Stability2023Paulina Stachula, Katarzyna Kapela, Ewelina Malecka, Kamila Jaronczyk, Jacek Patryn, Nina Siwirykow, Maria Bucholc, Malgorzata Marczak, Maciej Kotlinski and Rafal ArchackiUniversity of Warsaw & Institute of Biochemistry and Biophysics PAS

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extended-methodthermo-orbitrap-exploris-480
A chemoproteomic platform for reactive fragment profiling against the deubiquitinases2023Rosa Cookson, Aini Vuorinen, Jonathan Pettinger, Cassandra R. Kennedy, Joanna M. Kirkpatrick, Rachel E. Peltier-Heap, Andrew Powell, Ambrosius P. Snijders, Mark Skehel, David House, Katrin Rittinger and Jacob T. BushGSK & The Francis Crick Institute,

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30-spd 60-spdthermo-orbitrap-fusion-lumos
Systematic Adaptation of Bacillus licheniformis to 2-Phenylethanol Stress2023Yangyang Zhan,Haixia Xu, Hween Tong Tan, Ying Swan Ho, Dongxiao Yang, Shuwen Chen, Dave Siak-Wei Ow, Xin Lv, Fang Wei, Xuezhi Bi and Shouwen ChenHubei University, Bioprocessing Technology Institute (BTI) & Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences

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30-spdsciex-tripletof-6600-ms-system
SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation2023Solveig A. Krapf, Jenny Lund, Hege G. Bakke, Tuula A. Nyman, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen and Eili T. KaseUniversity of Oslo, Oslo University Hospital & AstraZeneca

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extended-methodsciex-tripletof-6600-ms-system
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus2023Nicholas H Harbin, Daniel J Lustberg, Cheyenne Hurst, Jean-Francois Pare, Kathryn M Crotty, Alaina L Waters, Samantha M Yeligar, Yoland Smith, Nicholas T Seyfried, David Weinshenker and John R HeplerEmory University School of Medicine

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extended-methodthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Label-free single cell proteomics utilizing ultrafast LC and MS instrumentation: A valuable complementary technique to multiplexing2023Manuel Matzinger, Rupert L. Mayer & Karl MechtlerVienna BioCenter,

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whisper-20spd whisper-40spd
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry2023Pavan Baichan, Previn Naicker, Tanya Nadine Augustine, Martin Smith, Geofrey Candy, John Devar and Ekene Emmanuel NwekeUniversity of the Witwatersrand, Council for Scientifc and Industrial Research & Chris Hani-Baragwanath Academic Hospital

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60-spdsciex-tripletof-6600-ms-system
A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics2023Thierry M. Nordmann, Lisa Schweizer, Andreas Metousis, Marvin Thielert, EdwinRodriguez, Lise Mette Rahbek-Gjerdrum, Pia-Charlotte Stadler, Michael Bzorek, Andreas Mund, Florian A. Rosenberger & Matthias MannMax Planck Institute of Biochemistry, Zealand University Hospital, University Hospital Munich & University of Copenhagen

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whisper-20spdbruker-timstof-scp
Vacuum Insulated Probe Heated ElectroSpray Ionization source (VIP-HESI) enhances micro flow rate chromatography signals in the Bruker timsTOF mass spectrometer2023Mukul K. Midha, Charu Kapil, Michal Maes, David H. Baxter, Seamus R. Morrone, Timothy J. Prokop & Robert L. MoritzInstitute for Systems Biology, , , ,

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100-spd 200-spd 30-spd 60-spd extended-methodbruker-timstof-pro
Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum2023Fredrik Leo, Gunnel Svensäter, Rolf Lood, Claes WickströmMalmö University, Genovis AB, Lund University

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thermo-q-exactive-hf-x
ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast2023Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska, Roza KucharczykPolish Academy of Sciences

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thermo-orbitrap-exploris-480
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-192023Gabriel Hirdman, Embla Bodén, Sven Kjellström, Carl‑Johan Fraenkel, Franziska Olm, Oskar Hallgren and Sandra LindstedtLund University, Department of Infection Control Region Skåne and Skåne University Hospital

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60-spdbruker-timstof-pro
Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome2023Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock, Amiq Gazdhar, Gisela Kuhn, Peter Angel, Saverio Bellusci, Jürgen Brinckmann, Ulrich auf dem Keller, Sabine Werner and Mattia R. BordoliETH Zurich, Technical University of Denmark, University of Lübeck, University Hospital Bern, German Cancer Research Center, German Lung Research Center & Universities of Giessen and Marburg Lung Center

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30-spdthermo-q-exactive-hf-x
No-stain protein labeling as a potential normalization marker for small extracellular vesicle proteins2023Anjugam Paramanantham, Rahmat Asfiya, Siddharth Das, Grace McCully & Akhil SrivastavaUniversity of Missouri School of Medicine

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30-spdtimstof-pro-2
An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices2023Martina Puzio, Niamh Moreton, Mairéad Sullivan, Caitriona Scaife, Jeffrey C. Glennon & John J. O’ConnorUniversity College Dublin

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30-spdbruker-timstof-pro
First trimester serum apolipoproteins in the prediction of late-onset preeclampsia2023Emma J. Bendix, Julie D. Ravn, Lene Sperling & Martin OvergaardOdense University Hospital & University of Southern Denmark

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60-spdthermo-altis-triple-quadrupole
A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics2023Thierry M. Nordmann, Lisa Schweizer, Andreas Metousis, Marvin Thielert, Edwin Rodriguez, Lise Mette Rahbek-Gjerdrum, Pia-Charlotte Stadler, Michael Bzorek, Andreas Mund, Florian A. Rosenberger & Matthias MannMax Planck Institute of Biochemistry, Zealand University Hospital, LMU Munich & University of Copenhagen

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whisper-20spdbruker-timstof-scp
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H12023Stephen Abini-Agbomson, Kristjan Gretarsson, Rochelle M. Shih, Laura Hsieh, Tracy Lou, Pablo De Ioannes, Nikita Vasilyev, Rachel Lee, Miao Wang, Matthew Simon, Jean-Paul Armache, Evgeny Nudler, Geeta Narlikar, Shixin Liu, Chao Lu & Karim-Jean ArmacheNew York University Grossman School of Medicine, Columbia University Irving Medical Center, The Rockefeller University, University of California, Howard Hughes Medical Institute, Yale University & Pennsylvania State University

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extended-methodthermo-orbitrap-fusion
Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC2023Stephan Kamrad, Clara Correia-Melo, Lukasz Szyrwiel, Simran Kaur Aulakh, Jürg Bähler, Vadim Demichev, Michael Mülleder & Markus RalserCharité Universitätsmedizin Berlin, The Francis Crick Institute, University College London, University of Oxford & Max Planck Institute for Molecular Genetics

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extended-methodtimstof-pro-2
Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo Like Kinase 1 (PLK-1) in C. elegans embryos2023Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Véronique Legros, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer and Lionel PintardUniversité Paris Cité, Programme équipe Labellisée Ligue contre le Cancer, Johns Hopkins University School of Medicine & CSIC/JA/Universidad Pablo de Olavide

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30-spdtimstof-pro-2
Label-free single cell proteomics utilizing ultrafast LC and M Sinstrumentation: A valuable complementary technique to multiplexing2023Manuel Matzinger, Rupert L. Mayer & Kar l. MechtlerVienna BioCenter,

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whisper-20spd whisper-40spd
Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition2023Maarten P. Bebelman, Caitrin Crudden, Bart Snieder, Evangelia Thanou, Catharina J.M. Langedijk, Margarida Viola, Steven Eleonora, Urszula Baginska, Olaf Cotugno, Jan Paul M. Bebelman, Monique A.J. van Eijndhoven, Leontien Bosch, Ka Wan Li, Martine J. SmitVrije Universiteit Amsterdam, University Medical Center Utrecht, Université de Paris & Utrecht Universit

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30-spdtimstof-pro-2
Optimizing linear ion trap data independent acquisition towards single cell proteomics2023Teeradon Phlairaharn, Zilu Ye, Elena Krismer, Anna-Kathrine Pedersen, Maik Pietzner, Jesper V. Olsen, Erwin M. Schoof and Brian C. SearleUniversity of Copenhagen, Technical University of Munich, Germany, Berlin Institute of Health at Charité–Universitätsmedizin & The Ohio State University,

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DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes2023Fabian Frommelt, Andrea Fossati, Federico Uliana, Fabian Wendt, Xue Peng, Moritz Heusel, Bernd Wollscheid, Ruedi Aebersold, Rodolfo Ciuffa and Matthias GstaigerETH Zurich, University of California San Francisco, J. David Gladstone Institutes, ETHZ Zurich & Evosep Biosystems

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60-spdthermo-q-exactive-970-tm-plus-hybrid-quadrupole-orbitrap
INPP5D/SHIP1 regulates inflammasome activation in human microglia2023Vicky Chou, Seeley B. Fancher, Richard V. Pearse II, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Phillip L. De Jager, Vilas Menon & Tracy L. Young-PearseBrigham and Women’s Hospital and Harvard Medical School, Columbia University Medical Center, Emory School of Medicine & Rush University Medical Center

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60-spdthermo-orbitrap-eclipse-tribid
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer’s disease risk gene SORL12023Hyo Lee, Aimee J. Aylward, Richard V. Pearse II, Yi-Chen Hsieh, Zachary M. Augur, Courtney R. Benoit, Vicky Chou, Allison Knupp, Cheryl Pan, Srilakshmi Goberdhan, Duc M. Duong, Nicholas T. Seyfried, David A. Bennett, Hans-Ulrich Klein, Philip L. De Jager,Brigham and Women’s Hospital and Harvard Medical School, University of Washington, Emory School of Medicine, Rush University Medical Center & Columbia University Irving Medical Center

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60-spdthermo-orbitrap-eclipse-tribid
A Streamlined High-Throughput Plasma Proteomics Platform for Clinical Proteomics with Improved Proteome Coverage, Reproducibility, and Robustness2023Jongmin Woo and Qibin ZhangUniversity of North Carolina

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60-spdthermo-orbitrap-exploris-240
A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics2023Arthur Viode, Patrick van Zalm, Kinga K. Smolen, Benoit Fatou, David Stevenson, Meenakshi Jha, Ofer Levy, Judith Steen and Hanno SteenBoston Children's Hospital, Harvard Medical School, Maastricht University and Broad Institute of MIT and Harvard

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60-spdtimstof-pro-2
Towards a Standardized Omics Platform with the 30 samples per day method2023EvosepEvosep

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Rapid Profiling of Protein Complex Reorganization in Perturbed Systems2023Isabell Bludau, Charlotte Nicod, Claudia Martelli, Peng Xue, Moritz Heusel, Andrea Fossati, Federico Uliana, Fabian Frommelt, Ruedi Aebersold, and Ben C. CollinsETH Zürich, Max Planck Institute of Biochemistry, Lund University, University of California San Francisco, Queen’s University of Belfast

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60-spdsciex-tripletof-6600-ms-system
Experimental strategies to improve drug-target identification in mass spectrometry-based thermal stability assays2023Clifford G. Phaneuf, Konstantin Aizikov, Dmitry Grinfeld, Arne Kreutzmann, Daniel Mourad, Oliver Lange, Daniel Dai, Bailin Zhang, Alexei Belenky, Alexander A. Makarov & Alexander R. IvanovNortheastern University, Thermo Fisher Scientific, Disease Profiling and Functional Genomics, Tarmeta Biosciences

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30-spdthermo-orbitrap-exploris-480
Foresight in clinical proteomics: current status, ethical considerations, and future perspectives2023Filip Mundt, Nicolai J. Wewer Albrechtsen, Sebastian Porsdam Mann, Peter Treit, Medini Ghodgaonkar-Steger, Martina O’Flaherty, Reinout Raijmakers, Juan Antonio Vizcaíno, Albert J.R. Heck, Matthias MannUniversity of Copenhagen, University of Oxford, Max Planck Institute of Biochemistry, Utrecht University, European Bioinformatics Institute (EMBL-EBI)

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thermo-orbitrap-exploris-480
Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype2023Miao Chen,Frank Koopmans, Iryna Paliukhovich,Sophie J. F. van der Spek, Jian Dong, August B. Smit, Ka Wan LiVrije Universiteit Amsterdam, Boston University

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30-spdtimstof-pro-2
Dynamic antagonism between key repressive pathways maintains the placental epigenome2023Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, SimTechnische Universität Berlin, , Max Planck Institute for Molecular Genetics, Freie Universität Berlin, Karolinska Institutet, Max-Delbrück Center for Molecular Medicine, Universitätsklinikum Schleswig-Holstein Campus Kiel, Yale School of Medicine, Broad

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30-spdbruker-timstof-scp
Myosin inhibitor reverses hypertrophic cardiomyopathy in pediatric iPSC-cardiomyocytes to mirror variant correction2023Caroline Kinnear, Abdelrahman Said, Guoliang Meng, Yimu Zhao, Erika Y Wang, Neha Parmar, Wei Wei, Filio Billia, MD, Craig A Simmons, Milica Radisic, James Ellis, Seema MitalThe Hospital for Sick Children, University of Toronto, University Health Network, Massachusetts Institute of Technology, Ted Rogers Centre for Heart Research

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60-spdthermo-orbitrap-fusion-lumos
Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis2023Miles Piper, Maureen Hoen, Laurel B. Darragh, Michael W. Knitz, Diemmy Nguyen, Jacob Gadwa, Greta Durini, Idil Karakoc, Abby Grier, Brooke Neupert, Benjamin Van Court, Khalid N.M. Abdelazeem, Justin Yu, Nicholas A. Olimpo, Sophia Corbo, Richard Blake RossUniversity of Colorado, University of Colorado

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Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer’s Disease Mouse Model2023Evangelia Thanou, Frank Koopmans, Débora Pita-Illobre, Remco V. Klaassen,Berna Özer, Ioannis Charalampopoulos, August B. Smit, and Ka Wan LiAmsterdam Neuroscience, University of Crete, Foundation for Research and Technology Hellas

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30-spdtimstof-pro-2
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells2023Deepti Talwar, Colin G. Miller, Justus Grossmann, Lukasz Szyrwiel, Torsten Schwecke, Vadim Demichev, Ana-Matea Mikecin Drazic, Anand Mayakonda, Pavlo Lutsik, Carmen Veith, Michael D. Milsom, Karin Müller-Decker, Michael Mülleder, Markus Ralser  & Tobias PNature Metabolism

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15-spdtimstof-pro-2
Flexibility, speed, and throughput for high proteome coverage using Zeno SWATH data-independent acquisition (DIA) coupled with the Evosep One system2023Patrick Pribil and Ihor BatruchSciex, , , , , ,

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100-spd 200-spd 30-spd 300-spd 500-spd 60-spdtimstof-pro-2 sciex-zenotof-7600
A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project2023Maria Grazia Andreassi, Nadia Haddy, Mats Harms-Ringdahl, Jonica Campolo, Andrea Borghini, François Chevalier, Jochen M. Schwenk, Brice Fresneau, Stephanie Bolle, Manuel Fuentes and Siamak HaghdoostCNR National Research Council Institute of Clinical Physiology, Université Paris-Saclay, Stockholm University, CEA-CNRS-ENSICAEN-University of Caen Normandy, Advanced Resource Center for HADrontherapy in Europe, SciLifeLab and University of Salamanca-CSIC

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60-spdtimstof-pro-2
Characteristics of size-exclusion chromatography enriched porcine follicular fluid extracellular vesicles2023Kinga Kaminska, Kasun Godakumara, Bianka Swiderska, Agata Malinowska, Getnet Midekessa, Kamila Sofinska, Jakub Barbasz, Alireza Fazeli and Malgorzata GrzesiakJagiellonian University, Estonian University of Life Sciences, University of Tartu, Polish Academy of Sciences, University of Sheffield

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extended-methodthermo-orbitrap-exploris-480
A desert Chlorella sp. that thrives at extreme high-light intensities using a unique photoinhibition protection mechanism2023Guy Levin, Michael Yasmin, Varda Liveanu, Carmit Burstein, Rawad Hanna, Oded Kleifeld, Marc C. Simanowitz, Ayala Meir, Yaakov Tadmor, Joseph Hirschberg, Noam Adir and Gadi SchusterTechnion, Hebrew University of Jerusalem & Newe Ya'ar Research Center

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30-spdthermo-q-exactive-hf
Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer2023V. Nieddu, V. Melocchi, C. Battistini, G. Franciosa, M. Lupia, C. Stellato, G. Bertalot, J. V. Olsen, N. Colombo, F. Bianchi and U. CavallaroEuropean Institute of Oncology IRCSS, Fondazione IRCCS Casa Sollievo della Sofferenza, University of Copenhagen, APSS, University of Trento and University of Milan-Bicocca Centre for Medical Sciences – CISMed, taly University of Milan-Bicocca, ondazione I

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30-spdthermo-q-exactive-480
Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise2023Daniel T. Cervone, Roger Moreno-Justicia, Júlia Prats Quesada and Atul S. DeshmukhUniversity of Copenhagen, ,

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Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation2023Larisa Chernyaeva, Giorgio Ratti, Laura Teirilä, Satoshi Fudo, Uni Rankka, Anssi Pelkonen, Paula Korhonen, Katarzyna Leskinen, Salla Keskitalo, Kari Salokas, Christina Gkolfinopoulou, Katrina E Crompton, Matti Javanainen, Lotta Happonen, Markku Varjosalo,University of Helsinki, University of Eastern Finland, National Center for Scientific Research "Demokritos", Newcastle University, Lund University and Kuopio University Hospital

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60-spdbruker-timstof-pro
Simultaneous targeting of PD-1 and IL-2Rbg with radiation therapy inhibits pancreatic cancer growth and metastasis2023Miles Piper, Maureen Hoen, Laurel B. Darragh, Michael W. Knitz, Diemmy Nguyen, Jacob Gadwa, Greta Durini, Idil Karakoc, Abby Grier, Brooke Neupert, Benjamin Van Court, Khalid N.M. Abdelazeem, Justin Yu, Nicholas A. Olimpo, Sophia Corbo, Richard Blake RossUniversity of Colorado and Roche Innovation Center Zurich

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whisper-20spdbruker-timstof-scp
In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology2023Filip Mundt, Annelaura Bach Nielsen, Josephine Kerzel Duel, Christina Westmose Yde, Martina Amnitzbøll Eriksen, Ulrik Lassen, Finn Cilius Nielsen, Kristoffer Rohrberg and Matthias MannUniversity of Copenhagen, Novo Nordisk, Copenhagen University Hospital, Rigshospitalet and Max Planck Institute of Biochemistry

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30-spdbruker-timstof-scp
Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating2023Andreia Cerqueira, Francisco Romero-Gavilán, Heike Helmholz, Mikel Azkargorta, Félix Elortza, Mariló Gurruchaga, Isabel Goñi, Regine Willumeit-Römer and Julio SuayUniversitat Jaume, Helmholtz-Zentrum Hereon Institute of Metallic Biomaterials, CIC bioGUNE and University of the Basque Country

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30-spdbruker-timstof-pro
Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins2023David C. Nieman, Jongmin Woo, Camila A. Sakaguchi, Ashraf M. Omar, Yang Tang, Kierstin Davis, Alessandra Pecorelli, Giuseppe Valacchi and Qibin ZhangAppalachian State University, University of North Carolina at Greensboro, North Carolina State University and University of Ferrara

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60-spdthermo-orbitrap-exploris-480
Resolving the Temporal Splenic Proteome during Fungal Infection for Discovery of Putative Dual Perspective Biomarker Signatures2023Benjamin Muselius, Florence Roux-Dalvai, Arnaud Droit and Jennifer Geddes-McAlisterUniversity of Guelph, CHU de Québec - Université Laval Research Center and University of Guelph

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60-spdthermo-orbitrap-exploris-480
Brain molecular mechanisms in Rasmussen encephalitis2023Dominique F. Leitner, Ziyan Lin, Zacharia Sawaged, Evgeny Kanshin, Daniel Friedman, Sasha Devore, Beatrix Ueberheide, Julia W. Chang, Gary W. Mathern, Jasper J. Anink, Eleonora Aronica, Thomas Wisniewski and Orrin DevinskyNYU Grossman School of Medicine, University of California, University of Amsterdam and Epilepsy Institutes of the Netherlands Foundation

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Comprehensive proteomic characterization and functional annotation of Siberian sturgeon seminal plasma proteins2023Natalia Kodzik, Andrzej Ciereszko, Mirosław Szczepkowski, Halina Karol, Sylwia Judycka, Agata Malinowska, Bianka Swiderska and Mariola A. DietrichPolish Academy of Sciences and Inland Fisheries Institute in Olsztyn

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Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer2023Vanessa Ortiz-Barahona, Marta Soler, Veronica Davalos, Carlos A. García-Prieto, Maxime Janin, Fernando Setien, Irene Fernández-Rebollo, Joan J. Bech-Serra, Carolina De La Torre, Sonia Guil, Alberto Villanueva, Pei-Hong Zhang, Li Yang, Marco Guarnacci, UlrJosep Carreras Leukaemia Research Institute. Barcelona Supercomputing Center (BSC), Germans Trias i Pujol Health Science Research Institute, Bellvitge Biomedical Research Institute, University of Chinese Academy of Sciences, l, Fudan University and Shangh

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Fully automated, rapid, robust sample loading on Evotip Pure with the Agilent AssayMAP Bravo2023Evosep BiosystemsEvosep Biosystems, ,

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100-spd whisper-40spdtimstof-pro-2 sciex-zenotof-7600
End-to-end, fully automated digestion protocol and Evotip Pure workflow on the Opentrons OT-22023Evosep BiosystemsEvosep Biosystems,

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100-spd whisper-40spdtimstof-pro-2
Evosep One solves the proteomics dilemma – covering high throughput analysis and proteome depth2023Evosep Biosystems, , , ,

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100-spd 200-spd 30-spd 300-spd 60-spd
A standardized separation method with a throughput of 300 samples per day2023EvosepEvosep

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300-spdthermo-orbitrap-exploris-480
Towards a Standardized Omics Platform with the 200 samples per day method2023EvosepEvosep

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200-spdthermo-orbitrap-exploris-480
Towards a Standardized Omics Platform with the 100 samples per day method2023EvosepEvosep

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100-spdthermo-orbitrap-exploris-480
Towards a Standardized Omics Platform with the 60 samples per day method2023EvosepEvosep

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60-spdthermo-orbitrap-exploris-480
Evotip Pure simplifies workflows with excellent reproducibility, storage and recovery2023Evosep Biosystems, ,

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100-spd 60-spd whisper-40spd
A specialized method using Whisper Flow technology with a throughput of 40 samples per day2023Evosep Biosystems

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whisper-40spd
A standardized separation method with a throughput of 500 samples per day2023Evosep Biosystems

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500-spd
A specialized method using Whisper Flow technology with a throughput of 80 samples per day2023Evosep Biosystems

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whisper-80-spd
A specialized method using Whisper Flow technology with a throughput of 20 samples per day2023Evosep Biosystems

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whisper-20spd
A specialized separation method for hydrophobic targets with the High Organic method2023Evosep Biosystems

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high-organic-method
More proteome coverage in a single experiment with the Extended method2023Evosep Biosystems

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extended-method
Evaluation of a ‘plug and play’ nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens2023Georgia Mitsa, Vincent R Richard, Yasamin Majedi, Josiane Lafleur, Adriana Aguilar-Mahecha, Mark Basik, Christoph H BorchersMcGill University, Jewish General Hospital

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15-spdthermo-q-exactive
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b2023Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, KlaudiCenter for Cooperative Research in Biosciences, NOVA School of Science and Technology, University of La Rioja,

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30-spdbruker-timstof-pro
Vacuum Insulated Probe Heated Electrospray Ionization Source Enhances Microflow Rate Chromatography Signals in the Bruker timsTOF Mass Spectrometer2023Mukul K. Midha, Charu Kapil, Michal Maes, David H. Baxter, Seamus R. Morrone, Timothy J. Prokop, and Robert L. MoritzInstitute for Systems Biology, , , ,

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100-spd 15-spd 200-spd 30-spd 60-spdbruker-timstof
Co-administration of angiotensin II and simvastatin triggers kidney injury upon heme oxygenase-1 deficiency2023Aleksandra Kopacz, Damian Kloska, Dominik Cysewski, Izabela Kraszewska, Karolina Przepiorska, Małgorzata Lenartowicz, Agnieszka Łoboda, Anna Grochot-Przęczek, Witold Nowak, Alicja Jozkowicz, and Aleksandra Piechota-PolanczykJagiellonian University, Polish Academy of Sciences, and Białystok,

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30-spdthermo-orbitrap-exploris-480
The protein and miRNA profile of plasma extracellular vesicles (EVs) can distinguish feline mammary adenocarcinoma patients from healthy feline controls2023Jane Howard, John Browne, Stephanie Bollard, Susan Peters, Ciara Sweeney, Kieran Wynne, Shirley Potter, Amanda McCann & Pamela KellyUniversity College Dublin, Mater Misericordiae University Hospital

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30-spdbruker-timstof-pro
DIS3 ribonuclease prevents the cytoplasmic accumulation of lncRNAs carrying non-canonical ORFs, which represent a source of cancer immunopeptides2023Dominika Foretek, Marc Gabriel, Isabelle Hatin, Julien Jarroux, Marina Pinskaya, Elise Pepermans, Kurt Boonen, Rachel Topno, Vera Slaninova, Marina Serna, Oscar Llorca, Geert Baggerman, Edouard Bertrand, Steven West, Olivier NamyInstitut Curie, Institute for Integrative Biology of the Cell, Weill Cornell Medicine, Institut Curie-CNRS, University of Antwerp, Institut Genetique Humaine, Spanish National Cancer Research Center (CNIO), Institut de Génétique Humaine, University of

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30-spdbruker-timstof-pro
ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast2023Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska & Roza KucharczykPolish Academy of Sciences

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TIMSTOF Compass 4.0 Methods – LCMS and MALDI – OrsburnLab 2023 v12023Benjamin OrsburnThe Johns Hopkins University School of Medicine

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Topological defects at smectic interfaces as a potential tool for the biosensing of living microorganisms2023Vajra S. Badha, Tagbo H.R. Niepa, and Mohamed Amine GharbiaUniversity of Massachusetts Boston, Carnegie Mellon University,

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Profiling of the Klebsiella pneumoniae Phosphoproteome under Iron-Limited and Iron-Replete Conditions2023Chelsea Reitzel, Arjun Sukumaran, Benjamin Muselius, Siobhan O’Connor, Jennifer Geddes-McAlisterUniversity of Guelph

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Cross-Linking Mass Spectrometry on P-Glycoprotein2023Gabriella Gellen, Eva Klement, Kipchumba Biwott, Gitta Schlosser,Gergő Kalló, Éva Csősz, Katalin F. Medzihradszky and Zsolt BacsoELTE Eötvös Loránd University, University of Debrecen, HCEMM, BRC

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extended-methodthermo-orbitrap-fusion-lumos
AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF2023Zhi‑Qing Zhu, Tian Zhang, Shuo Chang, Zhen‑Hua Ren and Qin ZhangFirst Affiliated Hospital of Anhui Medical University, Anhui Medical University

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bruker-timstof
Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins2023John Yates III, Ahrum Son, Hyunsoo Kim, Jolene Diedrich, Tom Bamberger, Daniel McClatchyScripps Research Institute, Chungnam National University

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30-spdbruker-timstof-pro
Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for their function2023Kai Liu, Ralf Nilsson, Elisa Lázaro-Ibáñez, Hanna Duàn, Tasso Miliotis, Marie Strimfors, Michael Lerche, Ana Rita Salgado Ribeiro, Johan Ulander, Daniel Lindén, Anna Salvati & Alan SabirshAstraZeneca, University of Gothenburg

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30-spdthermo-q-exactive-hf
Altered intratumoral immune composition after Nivolumab treatment in patients with recurrent glioblastoma2023Sine Hadrup, Signe Skadborg, Simone Maarup, Arianna Draghi, Annie Borch, Sille Hendriksen, Filip Mundt, Matthias Mann, Jane Skjoeth-Rasmussen, Christina Westmose Yde, Hans Poulsen, Benedikte Hasselbach, Inge Marie SvaneTechnical University of Denmark, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Rigshospitalet

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30-spdbruker-timstof-pro
Distribution and Chemistry of Phoenixin-14, a Newly Discovered Sensory Transmission Molecule in Porcine Afferent Neurons2023Urszula Mazur, Ewa Lepiarczyk, Paweł Janikiewicz, Elżbieta Łopieńska-Biernat, Mariusz Krzysztof Majewski and Agnieszka BossowskaUniversity of Warmia and Mazury in Olsztyn

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15-spdthermo-orbitrap-exploris-480
A genetic code change in progress: tRNA-Leu(CAG) is conserved in most Saccharomycopsis yeast 3 species but is non-essential and does not compete with tRNA-Ser(CAG) in translation2023Eoin Ó Cinnéide, Caitriona Scaife, Eugene Dillon, Kenneth H. WolfeUniversity College Dublin

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15-spdbruker-timstof-pro
Rapid and robust PTM peptide mapping for biologics with the Evosep One and the ZenoTOF 76002023Moritz Heusel, Stephen Lock, Nick Morrice, Sibylle Heidelberger, Jakob Bunkenborg, Michael Barrett Andersen, Nicolai BacheEvosep Biosystems, SCIEX Macclesfield, , ,

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100-spd 200-spd 300-spd 60-spdsciex-zenotof-7600
Pushing the boundaries for robust and high-throughput single cell analysis with Whisper Flow technology powered by dia-PASEF2023Dorte B. Bekker-Jensen, Christoph Krisp, David Hartlmayr, Anjali Seth, Ole B. Hørning, Magnus Huusfeldt, Andreia Almeida, Markus Lubeck, Gary Kruppa, Jarrod Sandow & Nicolai BacheEvosep Biosystems, Bruker Daltonics GmBH & Co. KG, Cellenion, IonOpticks, Bruker s.r.o,

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whisper-40spd whisper-80-spdbruker-timstof-scp
A complete and automated end-to-end sample preparation strategy for high-throughput and standardized proteomics with high sensitivity2023Magnus Huusfeldt, Joel Vej-Nielsen, Dorte B. Bekker-Jensen, Lasse Falkenby, Jesper V. Olsen, Nicolai BacheEvosep Biosystems, Denmark, University of Copenhagen, ,

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100-spd 30-spd whisper-40spd
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes2023Zilu Ye, Pierre Sabtier, Javier Martin-Gonzalez, Akihiro Eguchi, Dorte Bekker-Jensen, Nicolai Bache, Jesper V. OlsenDenmark, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, Core Facility for Transgenic Mice, Department of Experimental Medicine, University of Copenhagen, Denmark,

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whisper-40spdthermo-orbitrap-astral thermo-orbitrap-exploris-480
Protocol for high-throughput semi-automated label-free- or TMT-based phosphoproteome profiling2023Claire Koenig, Ana Martinez-Val, Previn Naicker, Stoyan Stoychev, Justin Jordaan, Jesper V. OlsenEvosep Biosystems, Odense, Denmark, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ReSyn Biosciences, Pretoria, South Africa, , ,

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30-spd 60-spd whisper-20spd whisper-40spdthermo-orbitrap-exploris-480
A seven-transmembrane methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases2023Tanveer S. Batth, Jonas L. Simonsen, Cristina Hernández-Rollán, Søren Brander, Jens Preben Morth, Katja S. Johansen, Morten H. H. Nørholm, Jakob B. Hoof & Jesper V. OlsenThe Novo Nordisk Foundation Center for Protein Research, University of Copenhagen,

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30-spd 60-spdthermo-orbitrap-exploris-480
Clinical proteomics reveals vulnerabilities in non-invasive breast ductal carcinoma and drives personalized treatment strategies2023Georgia Mitsa, Livia Florianova, Josiane Lafleur, Adriana Aguilar-Mahecha, Rene P. Zahedi, Sonia V del Rincon, Mark Basik, Christoph H Borchers, Gerald BatistSegal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC

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extended-methodthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix2023Shweta Mahajan, Deepti Dabral, Britt Coenen, Frans Bianchi, Niek van Hilten, Herre Jelger Risselada, Wouter H. Roos, Jesper Olsen, Laia Querol Cano, Geert van den BogaartDepartment of Molecular Immunology, Groningen Biomolecular Sciences and Biotechnology,

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30-spd 60-spdthermo-orbitrap-exploris-480
Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol2023Yuchuan Li, Manoj Amrutkar, Anette Vefferstad Finstadsveen, Knut Tomas Dalen, Caroline S Verbeke, Ivan P. GladhaugUniversity of Oslo, Oslo University Hospital Rikshospitalet

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30-spdbruker-timstof
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope2023Paulina Gregorczyk, Natalia Porebska, Dominika Żukowska, Aleksandra Chorążewska, Aleksandra Gędaj, Agata Malinowska, Jacek Otlewski, Małgorzata Zakrzewska, Łukasz OpalińskiFaculty of Biotechnology, Department of Protein Engineering, University of Wroclaw

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15-spdthermo-orbitrap-exploris-480
Effects of multiple stressors on pancreatic human islets proteome reveal new insights into the pathways involved2023Mehari Muuz Weldemariam, Putty-Reddy Sudhir, Jongmin Woo, Qibin ZhangCenter for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina, USA

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15-spdthermo-orbitrap-exploris-240
Mechanisms of nuclear pore complex disassembly by the mitotic Polo-like kinase 1 (PLK-1) in C. elegans embryos2023Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer, Lionel PintardUniversité Paris Cité, CNRS, Institut Jacques Monod

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30-spdtimstof-pro-2
Enhanced CellWall and Cell Membrane Activity Promotes Heat2023Li Wang, Aike Li, Jun Fang, Yongwei Wang, Lixian Chen, Lin Qiao, Weiwei WangAcademy of National Food and Strategic Reserves Administration, College of Bioscience and Biotechnology, Hunan Agricultural University, China

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thermo-orbitrap-exploris-480
Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae2023Ulises H. Guzman, Henriette Aksnes, Rasmus Ree, Nicolai Krogh, Magnus E. Jakobsson, Lars J. Jensen, Thomas Arnesen, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,

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30-spd 60-spdthermo-orbitrap-exploris-480
Quantitative multiorgan proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation2023Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes Bruno Müller-Reif,Wen-Feng Zeng, Sebastian Dintner, Thierry M Nordmann, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias MannDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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15-spdthermo-orbitrap-exploris-480
Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel2023Lisa Schweizer, Thierry M Nordmann, Patricia Skowronek, Maria Wahle, Wen-Feng Zeng, Xie-Xuan Zhou, Andreas-David Brunner, Sabrina Richter, Mitchell P Levesque, Fabian J Theis, Martin Steger, Matthias MannDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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whisper-40spdtimstof-pro
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL12023Hyo Lee, Aimee J. Aylward, Richard V. Pearse II, Vilas Menon, Jessica E. Young, Tracy L. Young-PearseAnn Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

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60-spdthermo-orbitrap-eclipse-tribid
Trans-Omics analysis of post injury thrombo-inflammation identifies endotypes and trajectories in trauma patients2023Christopher B. Erickson, Ian S. Lacroix, Margot Debot, Monika Dzieciatkowska, Terry R. Schaid, Morgan W. Hallas, Otto N. Thielen, Alexis L. Cralley, Anirban Banerjee, Ernest E Moore, Christopher C. Silliman, Angelo D’Alessandro, Kirk C. HansenDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus; Aurora, CO

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timstof-pro
An unconventional TOG domain is required for CLASP localization2023Nelly Gareil, Alison Gervais, Nicolas Macaisne, Guillaume Chevreux, Julie C. Canman, Jessica Andreani, Julien DumontUniversité Paris Cité, CNRS, Institut Jacques Monod

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30-spdtimstof-pro-2
Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver Diseases2023Mar Gil, Mikel Azkargorta, Carla Fuster, María Martínez-Gómez, Imma Raurell, Aurora Barberá, Juan Manuel Pericàs, Diana Hide, Felix Elortza, Joan Genescà, María MartellLiver Diseases, Vall d’Hebron Institut de Recerca (VHIR), Liver Unit, Hospital Universitari Vall d’Hebron (HUVH), Vall d’Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB)

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30-spdtimstof-pro
Deep and fast label-free Dynamic Organellar Mapping2023Julia P. Schessner, Vincent Albrecht, Alexandra K. Davies, Pavel Sinitcyn, Georg H. H. BornerDepartment of Proteomics and Signal Transduction, Systems Biology of Membrane Trafficking Research Group, Max-Planck Institute of Biochemistry, Martinsried, Germany,

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30-spd 60-spdthermo-orbitrap-exploris-480
Red Blood Cells from Individuals with Lesch–Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency2023Julie A. Reisz, Monika Dzieciatkowska, Daniel Stephenson, Fabia Gamboni, D. Holmes Morton, Angelo D’AlessandroDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, USA

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timstof-pro
Emergence of the Dickeya genus involved duplication of the OmpF porin and the adaptation of the EnvZ-OmpR signaling network2023Clémence Cochard, Marine Caby, Peggy Gruau, Edwige Madec, Michael Marceau, Iulia Macavei, Jérôme Lemoine, Chrystelle Le Danvic, Franck Bouchart, Brigitte Delrue, Sébastien Bontemps-Gallo, Jean-Marie LacroixUniv. Lille, CNRS, UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, France

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60-spdsciex-zenotof-7600
Very early life microbiome and metabolome correlates with primary vaccination variability in children2023Thomas P. Wyche, John Kang, Hendrik Wesseling, Begüm D. Topçuoğlu, Thomas Cairns, Theodore R. Sana, Robin M. Kaufhold, Julia M. Maritz, Christopher H. Woelk, Gokul Swaminathan, James E. Norton Jr., Michael E. PichicheroExploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts, USA

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whisper-40spdthermo-q-exactive-hf-x
Selective targeting of IL2Rbg combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC2023Jacob Gadwa, Maria Amann, Thomas E. Bickett, Christian Klein, Angelo D’Alessandro, Sana D. KaramDepartment of Radiation Oncology, University of Colorado, Anschutz Medical Campus, Aurora, USA,

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15-spd 30-spdtimstof-pro
MassSpecPreppy – an end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications2023Alexander Reder, Christian Hentschker, Leif Steil, Manuela Gesell Salazar, Elke Hammer, Vishnu M. Dhople, Thomas Sura, Ulrike Lissner, Hannes Wolfgramm, Denise Dittmar, Marco Harms, Kristin Surmann, Uwe Volker, Stephan MichalikUniversity Medicine Greifswald: Greifswald, DE, ,

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timstof-pro-2 thermo-fisher-ultimate-3000 thermo-orbitrap-exploris-480
Proteogenomic analysis of chemo-refractory high- grade serous ovarian cancer2023Jiayi Ji, Seungyeul Yoo, Chenwei Lin, Uliana J. Voytovich, Yajue Huang, Sun-Hee Lee, Lindsay Bergan, Travis D. Lorentzen, Mehdi Mesri, Henry Rodriguez, Andrew N. Hoofnagle, Zachary T. Herbert, Alexey I. Nesvizhskii, Bing ZhangLester and Sue Smith Breast Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA

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sciex-qtrap-6500
A micro-flow, high-pH, reversed-phase peptide fractionation and collection system for targeted and in-depth proteomics of low-abundance proteins in limiting samples2023Marta Zurawska, Mark Basik, Adriana Aguilar-Mahecha, Michal Dadlez, Dominik DomanskiMass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

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30-spdthermo-orbitrap-exploris-480
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity2023Samira Tabaei, Mohammad Reza Haghshenas, Ali Ariafar, Kambiz Gilany, Allan Stensballe, Shirin Farjadian, Abbas GhaderiShiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

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100-spdtimstof-pro-2
The potential of plasma HLA peptides beyond neoepitopes2023Maria Wahle, Marvin Thielert, Maximilian Zwiebel, Patricia Skowronek, Wen-Feng Zeng, Matthias MannDepartment Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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whisper-40spdbruker-timstof-ultra
Sex differences in brain protein expression and disease2023Yue Liu, Ekaterina S. Gerasimov, Selina M. Vattathil, Jiaqi Liu, David J. Cutler, Michael P. Epstein, Gabriëlla A. M. Blokland, Madhav Thambisetty, Juan C. Troncoso, Duc M. Duong, David A. Bennett, Allan I. Levey, Nicholas T. Seyfried, Thomas S. WingoDepartment of Human Genetics,Goizueta Alzheimer’s Disease Center, Emory University School of Medicine, Atlanta, GA, USA

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60-spdthermo-orbitrap-eclipse-tribid
A dynamic bias in chromatin protein deposition at G-quadruplex sites2023Thamar Jessurun Lobo, Deng Chen, Martijn R. H. Zwinderman, Peter M Lansdorp, Frank J. Dekker, Victor GuryevEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands

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30-spdthermo-orbitrap-exploris-480
Heterogeneity of radial spokes structural components and associated enzymes in Tetrahymena cilia2023Marta Bicka, Corbin Black, Avrin Ghanaeian, Ewa Joachimiak, Anna Osinka, Sumita Majhi, Anna Konopka, Ewa Bulska, Khanh Huy Bui, Dorota WlogaLaboratory of Cytoskeleton and Cilia Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland

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30-spdthermo-orbitrap-exploris-480
Exploring the benefits of differential mobility separation and SWATH data independent acquisition for complex proteomic sample analysis2023J.C.Yves Le Blanc, Eva Duchoslav, Lyle Burton, Steve Tate and Brad SchneiderSCIEX,

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100-spd 200-spdsciex-tripletof-6600-ms-system
Expanding the MAPPs Assay to Accommodate MHC-II Pan Receptors for Improved Predictability of Potential T Cell Epitopes2023Katharina Hartman, Guido Steiner, Michel Siegel, Cary M. Looney, Timothy P. Hickling, Katharine Bray-French, Sebastian Springer, Céline Marban-Doran, and Axel DucretRoche Pharma Research and Early Development, Roche Innovation Center Basel, Switzerland

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whisper-40spdtimstof-pro-2
Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition2023Pedro Aragon-Fernandez, Nil Üresin, Gergo Kovacs, Teeradon Phlairaharn, Benjamin Furtwängler, Jeff Op De Beeck, Sarah L. Skovbakke, Steffen Goletz, Simon Francis Thomsen, Ulrich auf dem Keller, Kedar N. Natarajan, Bo T. Porse & Erwin M. SchoofDepartment of Biotechnology and Biomedicine, Technical University of Denmark,

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whisper-20spd whisper-40spd
MassSpecPreppy—An end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications2023Alexander Reder, Christian Hentschker, Leif Steil, Manuela Gesell Salazar, Elke Hammer, Vishnu M. Dhople, Thomas Sura, Ulrike Lissner, Hannes Wolfgramm, Denise Dittmar, Marco Harms, Kristin Surmann, Uwe Völker, Stephan MichalikInterfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Germany

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30-spdtimstof-pro-2
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome2023Constantin Ammar, Sophia C. Mädler, Andreas Metousis, Patricia Skowronek, Maria Wahle, Katherine Madden, Janine Gote-Schniering, Anna Semenova, Herbert B. Schiller, Edwin Rodriguez, Thierry M. Nordmann, Andreas Mund & Matthias MannProteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany,

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30-spd whisper-40spdbruker-timstof-scp
Direct isolation of small extracellular vesicles from human blood using viscoelastic microfluidics2023Yingchao Meng, Yanan Zhang, Marcel Bühler, Shuchen Wang, Mohammad Asghari, Alessandra Stürchler, Bogdan Mateescu, Tobias Weiss, Stavros Stavrakis, Andrew J. DemelloInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Zürich, Switzerland

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30-spdbruker-timstof-pro
Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization2023Juliana K. Ilmain, Sofya S. Perelman, Maria C. Panepinto, Irnov Irnov, Nicolas Coudray, Nora Samhadaneh, Alejandro Pironti, Beatrix Ueberheide, Damian C. Ekiert, Gira Bhabha, Victor J. TorresDepartment of Microbiology, New York University Grossman School of Medicine, New York, USA

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15-spdthermo-q-exactive-hf
Postpartum defects in inflammatory response after gestational diabetes precede progression to type 2 diabetes: a nested case-control study within the SWIFT study2023Julie A.D. Van, Yihan Luo, Jayne S. Danska, Feihan Dai, Stacey E. Alexeeff, Erica P. Gunderson, Hannes Rost, Michael B. WheelerDepartment of Physiology, Faculty of Medicine, University of Toronto, Ontario, Canada

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60-spdbruker-timstof-pro
Production in Nicotiana benthamiana of a thermotolerant glucose oxidase that shows enzybiotic activity against Escherichia coli and Staphylococcus aureus2023David Talens-Perales, María Nicolau-Sanus, Julia Marín-Navarro, Julio Polaina, José-Antonio DaròsInstitute of Molecular and Cellular Biology of Plants (Higher Council of Scientific Research-Universitat Politècnica de València), Valencia, Spain

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100-spdbruker-timstof-flex
Müller glial cells located in the peripheral retina are more susceptible to high pressure: implications for glaucoma2023Xandra Pereiro, Noelia Ruzafa, Mikel Azkargorta, Felix Elorza, Arantxa Acera, António Francisco Ambrósio, Ana Raquel Santiago, Elena VecinoUniversity of the Basque Country: Universidad del Pais Vasco

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60-spdtimstof-pro
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 32023Julie Elisabeth Heggelund, Saykat Das, Jorunn Stamnaes, Rasmus Iversen & Ludvig M. SollidKG Jebsen Coeliac Disease Research Centre, Institute of Clinical Medicine, University of Oslo, Norway

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30-spdthermo-q-exactive-hf
Identification of Plasma Biomarkers from Rheumatoid Arthritis Patients Using an Optimized Sequential Window Acquisition of All THeoretical Mass Spectra (SWATH) Proteomics Workflow2023Liang Jin, Fei Wang, Xue Wang, Bohdan P. Harvey, Yingtao Bi, Chenqi Hu, Baoliang Cui, Anhdao T. Darcy, John W. Maull, Ben R. Phillips, Youngjae Kim, Gary J. Jenkins, Thierry R. Sornasse and Yu TianResearch & Development, AbbVie, North Chicago, IL, USA

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60-spdtimstof-pro
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction2023Alejandro Marmolejo-Garza, Marina Trombetta-Lima, Asmaa Oun, Jasmijn Hunneman, Tingting Chen, Jari Koistinaho, Sarka Lehtonen, Arjan Kortholt, Justina C. Wolters, Barbara M. Bakker, Bart J. L. Eggen, Erik Boddeke & Amalia DolgaDepartment of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Behavioral and Cognitive Neurosciences (BCN), University of Groningen, Groningen, The Netherlands

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30-spdthermo-orbitrap-exploris-480
A chemoproteomic platform for selective deubiquitinase inhibitor discovery2023Rosa Cookson, Aini Vuorinen, Jonathan Pettinger, Cassandra R. Kennedy, Joanna M. Kirkpatrick, Rachel E. Peltier-Heap, Andrew Powell, Ambrosius P. Snijders, Mark Skehel, David House, Katrin Rittinger, and Jacob T. BushCrick-GSK Biomedical LinkLabs, GSK, Gunnels Wood Road, Stevenage, Hertfordshire, UK,

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30-spd 60-spdthermo-orbitrap-fusion-lumos
Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus2023Nina Rostgaard, Markus Harboe Olsen, Sara Diana Lolansen, Nicolas Hernandez Nørager, Peter Plomgaard, Nanna MacAulay & Marianne JuhlerDepartment of Neurosurgery, The Neuroscience Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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60-spdthermo-orbitrap-exploris-480
Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism2023Ngoc Nguyen Lunde, Nimo Mukhtar Mohamud Osoble, Andrea Dalmao Fernandez, Alfreda S. Antobreh, Abbas Jafari, Sachin Singh, Tuula A. Nyman, Arild C. Rustan, Rigmor Solberg and G. Hege ThoresenSection for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Norway

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30-spdthermo-q-exactive-hf
Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification2023Florian S. Harking, Alberto J. Taurozzi, Zandra Fagernäs, Ricardo M. Godinho, Geoff M. Smith, Marcel Weiss, Tim Schüler, Shannon P. McPherron, Harald Meller, João Cascalheira, Nuno Bicho, Jesper V. Olsen, Jean-Jacques Hublin & Frido WelkerGlobe Institute, University of Copenhagen, Copenhagen, Denmark

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60-spdthermo-orbitrap-exploris-480
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue2023Andrew G. Chambers, David C. Chain, Steve M. Sweet, Zifeng Song, Philip L. Martin, Matthew J. Ellis, Claire Rooney and Yeoun Jin KimEarly Oncology, AstraZeneca, One MedImmune Way, Gaithersburg, MD 20878, USA

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30-spdthermo-orbitrap-fusion-lumos
Synaptic involvement of the human amygdala in Parkinson’s disease2023Sandra Villar-Conde, Veronica Astillero-Lopez, Melania Gonzalez-Rodriguez, Daniel Saiz-Sanchez, Alino Martinez-Marcos, Isabel Ubeda-Banon, Alicia Flores-CuadradoNeuroplasticity and Neurodegeneration Group, CRIB, Faculty of Medicine of Ciudad Real, University of Castilla-La Mancha (UCLM), Spain

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60-spdtimstof-pro
Dynamic extracellular proximal interaction profiling reveals Low-Density Lipoprotein Receptor as a new Epidermal Growth Factor signaling pathway component2023Rasha Al Mismar, Payman Samavarchi-Tehrani, Brendon Seale, Vesal Kasmaeifar, Claire E. Martin, Anne-Claude GingrasLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health, Toronto, Canada,

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30-spd 60-spdtimstof-pro-2
Sensitive and Specific Global Cell Surface N-Glycoproteomics Shows Profound Differences Between Glycosylation Sites and Subcellular Components2023Noortje de Haan, Ming Song, Oliver C. Grant, Zilu Ye, Fawzi Khoder Agha, Mikkel Koed Møller Aasted, Robert J. Woods, Sergey Y. Vakhrushev, and Hans H. WandallCopenhagen Center for Glycomics, University of Copenhagen, Copenhagen, Denmark

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30-spdthermo-orbitrap-exploris-480
Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer2023Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, and Emily E. BoscoEarly Oncology Research, Biologics Engineering and Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA

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30-spdthermo-orbitrap-exploris-480
The social and structural architecture of the yeast protein interactome2023André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau & Matthias MannMax-Planck Institute of Biochemistry, Martinsried, Germany

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60-spdtimstof-pro
Instrumentation at the leading edge of proteomics2023Trenton M. Peters-Clarke, Joshua J. Coon, Nicholas M. RileyDepartment of Chemistry, University of Washington, Seattle, WA, USA

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Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model2023Marwa Almosailleakh, Sofia Bentivegna, Samuele Narcisi, Sébasitien J. Benquet, Linn Gillberg, Carmen P. Montaño-Almendras, Simonas Savickas, Erwin M. Schoof, Amelie Wegener, Hérve Luche, Henrik E. Jensen, Christophe Côme & Kirsten GrønbækDepartment of Hematology, Rigshospitalet, 2100 Copenhagen, Denmark

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Deep topographic proteomics of a human brain tumour2023Simon Davis, Connor Scott, Janina Oetjen, Philip D. Charles, Benedikt M. Kessler, Olaf Ansorge & Roman FischerTarget Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford

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Mapping cardiac remodeling in chronic kidney disease2023Giulia Franciosa, Aurelien Dugourd, Julio Saez-Rodriguez, Sabine Neuss, Michael Lehrke, Peter Boor, Claudia Goettesch, Jesper V. Olsen, Thimoteus Speer, Tzong-Shi Lu, Kennth Lim, Jürgen Floege, Laura Denby, Ivan Costa, Rafael KramannClinic for Renal and Hypertensive Disorders, Rheumatological and Immunological Disease, University Hospital of the RWTH Aachen, Aachen, Germany

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30-spdthermo-orbitrap-exploris-480
Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography–Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study2023Lin Li, Christopher J Lyon, Sylvia M LaCourse, Wenshu Zheng, Joshua Stern, Jaclyn N Escudero, Wilfred Bundi Murithi, Lilian Njagi, Grace John-Stewart, Thomas R Hawn, Videlis Nduba, Wael Abdelgaliel, Thomas Tombler, David Horne, Li Jiang, Tony Y HuCenter for Cellular and Molecular Diagnostics, Department of Biochemistry and Molecular Biology, School of Medicine, Tulane University, New Orleans, LA, United States

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BioE3 identifies specific substrates of ubiquitin E3 ligases2023Orhi Barroso-Gomila, Laura Merino-Cacho, Veronica Muratore, Coralia Perez, Vincenzo Taibi, Elena Maspero, Mikel Azkargorta, Ibon Iloro, Fredrik Trulsson, Alfred C. O. Vertegaal, Ugo Mayor, Felix Elortza, Simona Polo, Rosa Barrio & James D. SutherlandCenter for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain

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30-spdtimstof-pro
High-throughput and scalable single cell proteomics identifies over 5000 proteins per cell2023Zilu Ye, Pierre Sabatier, Leander van der Hoeven, Teeradon Phlairaharn, David Hartlmayr, Fabiana Izaguirre, Anjali Seth, Hiren J. Joshi, Dorte B. Bekker-Jensen, Nicolai Bache, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark,

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whisper-40spd whisper-80-spdthermo-orbitrap-astral
High-throughput proteomics uncovers exercise training and type 2 diabetes–induced changes in human white adipose tissue2023Jeppe Kjærgaard Larsen, Rikke Kruse, Navid Sahebkhtiari, Roger Moreno-Justicia, Gerard Gomez Jorba, Maria H. Petersen, Martin E. De Almeida, Niels Ørtenblkad, Atul S. Deshmukh, Kurt HøjlundSteno Diabetes Center Odense, Odense University Hospital, Odense C, Denmark

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30-spdthermo-orbitrap-exploris-480
Diagnostic Utility of Proteogenomic Analysis for Inherited Bone Marrow Failure Syndrome2023Manabu Wakamatsu MDPhD, Hideki Muramatsu MD PhD, Hironori Sato MDPhD, Masaki Ishikawa, Daisuke Nakajima, Ryo Konno, Yusuke Kawashima, Motoharu Hamada MDPhD, Yusuke Okuno MD PhD, Osamu Ohara, Yoshiyuki Takahashi MD PhDDepartment of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan

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thermo-orbitrap-exploris-480
Novel Assay for Quantification of Free Light Chain (FLC) Dimers in Serum of Patients with Plasma Cell Dyscrasias2023Mariya Liyasova PhD, Michael Slade MDMSCI, Julie Fortier PhD, Ravi Vij MD MBA, Mark Fiala PhD, Liqiang Yang PhD, Bin Ma PhDRapid Novor Inc., Kitchener, Canada

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thermo-orbitrap-exploris-480
Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimens2023Stephan Eckert, Stephan A. Müller, Stephan Breimann, Pieter Giesbertz, Alexander M. Bernhardt, Lisa Schweizer, Vincent Albrecht, Daniel Teupser, Axel Imhof, Bernhard Kuster, Stefan F. Lichtenthaler, Matthias Mann, Jürgen Cox, and Stefanie M. HauckMetabolomics and Proteomics Core (MPC), Helmholtz Zentrum München,German Research Center for Environmental Health (GmbH), Munich, Germany,

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30-spd 60-spdthermo-orbitrap-exploris-480
INPP5D regulates inflammasome activation in human microglia2023Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B. Fancher, Alina Sigalov, Courtney R. Benoit, Hyo Lee, Matti Lam, Nicholas T. Seyfried, David A. Bennett, Philip L. De Jager, Vilas Menon & Tracy L. Young-PearseAnn Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

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60-spdthermo-orbitrap-eclipse-tribid
An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics2023Anuar Makhmut, Di Qin, David Hartlmayr, Anjali Seth, Fabian CosciaMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Spatial Proteomics Group, Berlin, Germany

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IMBAS-MS discovers organ-specific HLA peptide patterns in plasma2023Maria Wahle, Marvin Thielert, Maximilian Zwiebel, Patricia Skowronek, Wen-Feng Zeng, Matthias MannDepartment Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany, , ,

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15-spd 30-spd 60-spd whisper-40spdbruker-timstof-ultra
Immunopeptidomics in the Era of Single-Cell Proteomics2023Rupert L. Mayer and Karl MechtlerResearch Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria, , ,

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whisper-40spdbruker-timstof-scp bruker-timstof-ultra thermo-orbitrap-astral thermo-q-exactive-hf
Fully automated workflow for integrated sample digestion and Evotip loading enabling high-throughput clinical proteomics2023Anders H. Kverneland, Florian Harking, Joel Mario Vej-Nielsen, Magnus Huusfeldt, Dorte B. Bekker-Jensen, Inge Marie Svane, Nicolai Bache, Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, ,

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100-spd 30-spd 60-spdthermo-orbitrap-exploris-480
Proteomic comparison between non‐purified cerebrospinal fluid and cerebrospinal fluid‐derived extracellular vesicles from patients with Alzheimer’s, Parkinson’s and Lewy body dementia2023Yael Hirschberg, Natalia Valle‐Tamayo, Oriol Dols‐Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E. Vandenbroucke, Yannick Vermeiren, Kurt Boonen, and Inge MertensHealth Unit, Flemish Institute for Technological Research (VITO), Mol Belgium

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30-spdbruker-timstof-pro
Cryopreservation of highly extended pig spermatozoa remodels its proteome and counteracts polyspermic fertilization in vitro2023Inmaculada Parrilla, Josep M. Cambra, Cristina Cuello, Heriberto Rodriguez-Martinez, Maria A. Gil, Emilio A. MartinezDepartment of Medicine and Animal Surgery, International Excellence Campus for Higher Education and Research “Campus Mare Nostrum,”, University of Murcia, Murcia, Spain

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60-spdbruker-timstof-flex
Comparative proteomic analysis of human milk fat globules and paired membranes and mouse milk fat globules identifies core cellular systems contributing to mammary lipid trafficking and secretion2023Jayne F. Martin Carli, Monika Dzieciatkowska, Teri L. Hernandez, Jenifer Monks, James L. McManamanDivision of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

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A biotin targeting chimera (BioTAC) system to map small molecule interactomes in situ2023Andrew J. Tao, Jiewei Jiang, Gillian E. Gadbois, Pavitra Goyal, Bridget T. Boyle, Elizabeth J. Mumby, Samuel A. Myers, Justin G. English & Fleur M. FergusonDepartment of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA

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30-spdtimstof-pro-2
In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response2023Erica Stevenson, Yiwen R. Chen, Nabora S. Reyes, Tien Peng, Michael A. Matthay, Michela Traglia, Alexander R. Pico, Daniel F. Jarosz, Abigail Buchwalter, Sina Ghaemmaghami, Danielle L. Swaney, Isha H. JainInstitute of Cardiovascular Disease, Gladstone Institutes, San Francisco, CA, USA

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60-spdtimstof-pro-2
Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function2023Lina Wang, Dube Dheeraj Prakashchand, Nicholas P. Boyer, Veronica M. Saia-Cereda, Kristen Branes-Guerrero, Donald P. Pizzo, Pritha Bagchi, V.S. Sundar, Yong Tang, Utpal Das, David A. Scott, Padmini Rangaman, Yuki Ogawa, Subhojit RoyDepartment of Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, USA

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15-spdthermo-q-exactive-plus-hybrid-quadrupole-orbitrap
Multicenter Collaborative Study to Optimize Mass Spectrometry Workflows of Clinical Specimen2023Alexander M. Bernhardt, Lisa Schweizer, Vincent Albrecht, Daniel Teupser, Axel Imhof, Bernhard Kuster, Stefan F. Lichtenthaler, Matthias Mann, Jürgen Cox, and Stefanie M. HauckMetabolomics and Proteomics Core (MPC), Helmholtz Zentrum München,German Research Center for Environmental Health (GmbH), Munich, Germany, , , ,

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60-spdtimstof-pro thermo-orbitrap-exploris-480 thermo-orbitrap-fusion-lumos thermo-q-exactive-hf thermo-q-exactive-hf-x
Modeling the simultaneous dynamics of proteins in blood plasma and the cerebrospinal fluid in human in vivo2023Pierre Giroux, Jérôme Vialaret, Jana Kindermans, Audrey Gabelle, Luc Bauchet, Christophe Hirtz, Sylvain Lehmann, Jacques ColingeUniversité de Montpellier, Montpellier, France

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60-spdbruker-timstof-ht
Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters2023Nicoll Zeballos, Natalia Comino, Daniel Andrés-Sanz, Javier Santiago-Arcos, Mikel Azkargorta, Felix Elortza, Eleftheria Diamanti, and Fernando López-GallegoCenter for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), San Sebastián, Spain

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timstof-pro
Paracrine cross-talk between human adipose tissue-derived endothelial cells and perivascular cells accelerates the endothelialization of an electrospun ionomeric polyurethane scaffold2023Jeremy A. Antonyshyn, Kate D. MacQuarrie, Meghan J. McFadden, Anthony O. Gramolini, Stefan O.P. Hofer, J. Paul SanterreInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada

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15-spdthermo-q-exactive-plus
Sample loading protocol for Evotips2022

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Evotips: Quick guide2022Evosep

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A beginner’s guide to Evosep2022Nicolai Bache & Ireshyn GovenderEvosep, Resyn Biosciences

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Evosep One in the clinical biochemistry lab2022Nicolai Jacob Wewer Albrechtsen, Martin OvergaardOdense University Hospital, University of Southern Denmark, NNF center for protein research, University of Copenhagen

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Proteomics at the single cell level with Evosep Whisper and the timsTOF SCP2022Bruker Daltonics

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Unleash the power of DIA2022Patricia Skowronek, Yves Le Blanc, Ihor BatruchMax Planck Institute of Biochemistry, Sciex

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Evotip Pure: A new generation of Evotip2022Evosep

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Introducing Evotip Pure: A new generation of Evotip – It’s all in the tip2022Nicolai Bache, Dorte Bekker-JensenEvosep

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Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-192022Srikanth Mairpady Shambat, Alejandro Gómez-Mejia, Tiziano A. Schweizer, Markus Huemer, Chun-Chi Chang, Claudio Acevedo, Judith Bergada-Pijuan, Clément Vulin, Daniel A. Hofmaenner, Thomas C. Scheier, Sanne Hertegonne, Elena Parietti, Nataliya Miroshnikova,University Hospital of Zurich, University of Zurich, Switzerland

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30-spdbruker-timstof-pro
FASN-dependent de novo lipogenesis is required for brain development2022Daniel Gonzalez-Bohorquez, Isabel M. Gallego López, Baptiste N. Jaeger, Sibylle Pfammatter, Megan Bowers, Clay F. Semenkovich & Sebastian JessbergerUniversity of Zurich, Switzerland. University School of Medicine, St. Louis, US

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Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis2022Hanne Van Der Heijden, Benoit Fatou, Kacie Hoyt, Benjamin Goodlett, Camilo Jaimes, Hanno Steen, Jaymin UpadhyayBoston Children’s Hospital MA, USA, Maastricht University, Maastricht, The Netherlands, University of Amsterdam, Amsterdam, The Netherlands, BioSAS Consulting, Inc, Wellesley, MA, USA, McLean Hospital, Harvard Medical School, MA, Belmont, USA

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60-spdbruker-timstof-pro
Recent Developments in Clinical Plasma Proteomics—Applied to Cardiovascular Research2022Nicolai Bjødstrup Palstrøm, Rune Matthiesen, Lars Melholt Rasmussen, Hans Christian BeckOdense University Hospital, Odense, Denmark, Universidade NOVA de Lisboa, Lisbon, Portugal

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P018 Proteomic profile of serum and urine in newly diagnosed patients with Inflammatory Bowel Disease: new approach for biomarker discovery2022Montse Baldan Martin, Mikel Azkargorta Mujika, Lorena Ortega-MorenoHospital Universitario de La Princesa, CIC bioGune, Bilbao, Spain

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Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion2022Leonie van Leeuwen, Leonie H. Venema, Raphael Heilig, Henri G. D. Leuvenink, Benedikt M. KesslerUniversity of Groningen, Groningen, The Netherlands, Target Discovery Institute, University of Oxford, Oxford, UK, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK

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High-Field Asymmetric Waveform Ion Mobility Spectrometry and Parallel Reaction Monitoring Increases Sensitivity for Clinical Biomarker Quantitation from FormalinFixed, Paraffin-Embedded Tumor Biopsies2022Steve Sweet, David Chain, Wen Yu, Philip Martin, Marlon Rebelatto, Andrew Chambers,1 Fabiola Cecchi, Yeoun Jin KimTranslational Medicine, Oncology R&D, Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD

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Beta thalassemia minor is a beneficial determinant of red blood cell storage lesion2022Vassilis L. Tzounakas, Alkmini T. Anastasiadi, Davide Stefanoni, Francesca Cendali, Lorenzo Bertolone, Fabia Gamboni, Monika Dzieciatkowska, Pantelis Rousakis, Athina Vergaki, Vassilis Soulakis, Ourania E. Tsitsilonis, Konstantinos Stamoulis, Issidora S.Department of Biology, Section of Cell Biology and Biophysics, School of Science, National and Kapodistrian University of Athens., Department of Biochemistry and Molecular Genetics, University of Colorado, School of Medicine-Anschutz Medical Campus.

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Numb exon 9 inclusion regulates Integrinβ5 surface expression and promotes breast cancer metastasis2022Yangjing Zhang, Sascha E. Dho, Kamal Othman, Craig D. Simpson, Jessica Lapierre, Andrew Bondoc & C. Jane McGladeDepartment of Medical Biophysics, University of Toronto., The Arthur and Sonia Labatt Brain Tumour Research Centre., SPARC BioCentre, The Hospital for Sick Children.

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ABPP-HT* – Deep meets fast for activity-based profiling of deubiquitylating enzymes using advanced DIA and DDA mass spectrometry methods2022Hannah B. L. Jones, Raphael Heilig, Simon Davis, Roman Fischer, Benedikt M. Kessler, Adán Pinto-FernandezUniversity of Oxford

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100-spdbruker-timstof-pro
A fast and sensitive absolute quantification assay for the detection of sars-cov-2 peptides using parallel reaction monitoring mass spectrometry2022Akshada Gajbhiye, Atakan Nalbant, Tiaan Heunis, Frances Sidgwick, Andrew Porter, Yusri Taha, Matthias TrostNewcastle University

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Toxoplasma gondii ROP1 subverts murine and human innate immune restriction2022Simon Butterworth, Francesca Torelli, Eloise J. Lockyer, Jeanette Wagener, Ok-Ryul Song, Malgorzata Broncel, Matt R. G. Russell, Joanna C. Young, Moritz TreeckThe Francis Crick Institute, London.

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30-spdthermo-orbitrap-fusion-lumos
Antimicrobial resistance with the Evosep One2022Dimard Foudraine, Florence Roux DalvaiErasmus MC, Laval University

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Profiling the Plasma Apolipoproteome of Normo- and Hyperlipidemic Mice by Targeted Mass Spectrometry2022Lasse Bach Steffensen, Jannik Larsen, Didde Riisager Hansen, Thi My Linh Tha, Niels Strømvig Larsen, Hans Christian Beck, Lars Melholt Rasmussen, Martin OvergaardUniversity of Southern Denmark (SDU), Odense

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Using Targeted Liquid Chromatography-Tandem Mass Spectrometry to Rapidly Detect β-Lactam, Aminoglycoside, and Fluoroquinolone Resistance Mechanisms in Blood Cultures Growing E. coli or K. pneumoniae2022Dimard E. Foudraine, Lennard J. M. Dekker, Nikolaos Strepis, Stan J. Nispeling, Merel N. Raaphorst, Wendy Kloezen, Piet Colle, Annelies Verbon, Corné H. W. Klaassen, Theo M. Luider, Wil H. F. GoessensErasmus MC,

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100-spdthermo-orbitrap-fusion thermo-q-exactive
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation2022Kim Theilgaard-Mönch, Sachin Pundhir, Kristian Reckzeh, Jinyu Su, Marta Tapia, Benjamin Furtwängler, Johan Jendholm, Janus Schou Jakobsen, Marie Sigurd Hasemann, Kasper Jermiin Knudsen, Jack Bernard Cowland, Anna Fossum, Erwin SchoofUniversity of Copenhagen, Technical University of Denmark

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High sensitivity limited material proteomics empowered by data- independent acquisition on linear ion traps2022Teeradon Phlairaharn, Lukas R. Woltereck, Samuel Grégoire, Benjamin Furtwängler, Erwin M. SchoofTechnical University of Denmark,

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ASMS 2022 highlights: Robust and high-throughput analysis with ultra-high sensitivity2022Dorte Bekker-Jensen, Angela Mc Ardle, Nicolai BacheEvosep

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Improve and enhance your proteome coverage with the performance column for our long methods2022Evosep,

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30-spd extended-methodbruker-timstof-pro
A semi automated AssayMAP bravo protocol for robust Evotip loading and high-throughput analysis on the Evosep One2022Evosep

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Comprehensive proteomics with 8.000 proteins identified with DIA-PASEF using the 30 samples per day method2022Evosep

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Robust and high-throughput single cell proteomics with the Evosep One2022Evosep

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Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity2022Jaione Auzmendi-Iriarte, Maddalen Otaegi-Ugartemendia, Estefania Carrasco-Garcia, Mikel Azkargorta, Antonio Diaz, Ander Saenz-Antonanzas, Joaquin Andrés Andermatten, Mikel Garcia-Puga, Idoia GarciaUniversity of the Basque Country

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Development of Fast Photochemical Oxidation of Proteins for in Vivo Modification in Caenorhabditis elegans2022Jessica Arlett EspinoUniversity of Maryland,

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Nano-LC: An updated review2022Lian Shan, Barry R JonesLC-MS Biologics, QSquared Solutions

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APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons2022Chun-I Wu, Elizabeth A. Vinton, Richard V. Pearse II, Keunjung Heo, Aimee J. Aylward, Yi-Chen Hsieh, Yan Bi, Sopefoluwa Adeleye, Seeley Fancher, Duc M. Duong, Nicholas T. Seyfried, Thomas L. Schwarz & Tracy L. Young-PearseMolecular Psychiatry

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Chemical probing provides insight into the native assembly state of a bacterial microcompartment2022Daniel S. Trettel, William Resager, Beatrix M. Ueberheide, Conor C. Jenkins, Wade C.WinklerUniversity of Maryland, New York University Grossman School of Health, New York University Grossman School of Medicine

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DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes2022Anna Maria Sole Giordano, Marco Luciani, Francesca Gatto, Monah Abou Alezz, Chiara Beghè, Lucrezia Della Volpe, Alessandro Migliara, Sara Valsoni, Marco Genua, Monika Dzieciatkowska, Giacomo Frati, Julie Tahraoui-Bories, Silvia Clara Giliani, Simona OrcesJournal of Experimental Medicine

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DebaryOmics: an integrative –omics study to understand the halophilic behaviour of Debaryomyces hansenii2022Clara Navarrete, Benjamín J. Sánchez, Simonas Savickas, José Luis Martínez RuizDepartment of Biotechnology and Biomedicine,Technical University of Denmark

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Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes2022Shideh Mirhadi, Shirley Tam, Quan Li, Nadeem Moghal, Nhu-An Pham, Jiefei Tong, Brian J. Golbourn, Jonathan R. Krieger, Paul Taylor, Ming Li, Jessica Weiss, Sebastiao N. Martins-Filho ,Vibha Raghavan, Yasin Mamatjan, Aafaque A. Khan, Michael Cabanero, ShinNature Communications

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A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens2022Georgia Mitsa, Qianyu Guo, Christophe Goncalves, Samuel E J Preston, Vincent Lacasse, Adriana Aguilar-Mahecha, Naciba Benlimame, Mark Basik, Alan Spatz, Gerald Batist, Wilson H Miller Jr, Sonia V Del Rincon, René P Zahedi, Christoph H BorchersInternational Journal of Molecular Sciences

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Zwitter-ionic monolith-based spintip column coupled with Evosep One liquid chromatography for high-throughput proteomic analysis2022Yiran Su, Xi Wang, Yun Yang, Lijun Yang, Ruilian Xu, Ruijun TianSouthern Univrsity of Science and Technology, China, Jinan University, China,

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Inflammation-induced downregulation of succinate dehydrogenase regulates adrenocortical function2022Ivona Mateska, Anke Witt, Eman Hagag, Anupam Sinha, Canelif Yilmaz, Evangelia Thanou, Na Sun, Ourania Kolliniati, Maria Patschin, Heba Abdelmegeed, Holger Henneicke, Waldemar Kanczkowski, Ben Wielockx, Christos Tsatsanis, Andreas Dahl, Axel Walch, Ka WanTechnische Universität Dresden, Germany, Vrije Universiteit, Netherlands, Helmholtz Centrum München, Germany, University of Crete, Greece

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Evaluation of the Suitability of Dried Saliva Spots for In-Depth Proteome Analyses for Clinical Applications2022Hironori Sato, Daisuke Nakajima, Masaki Ishikawa, Ryo Konno, Ren Nakamura, Osamu Ohara, & Yusuke KawashimaDepartment of Applied Genomics, Kazusa DNA Research Institute, Department of Pediatrics, Graduate School of Medicine, Chiba University

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Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications2022Loïc Dayon, Ornella Cominetti & Michael AffolterProteomics, Bioanalytics Department, Nestlé Institute of Food Safety & Analytical Sciences, Institut des Sciences et Ingénierie Chimiques

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Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction2022Mehari Muuz Weldemariam, Jongmin Woo & Qibin ZhangUniversity of North Carolina at Greensboro

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Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes2022Mirolyuba Ilieva, Blanca Irene Aldana, Kasper Tore Vinten, Sonja Hohmann, Thomas William Woofenden, Renate Lukjanska, Helle S Waagepetersen, Tanja Maria MichelUniversity of Southern Denmark, Odense University Hospital, Aalborg University, University of Copenhagen

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30-spdthermo-orbitrap-fusion
Engineered SH2 Domains for Targeted Phosphoproteomics2022Gregory D. Martyn, Gianluca Veggiani, Ulrike Kusebauch, Seamus R. Morrone, Bradley P. Yates, Alex U. Singer, Jiefei Tong, Noah Manczyk, Gerald Gish, Zhi Sun, Igor Kurinov, Frank Sicheri, Michael F. Moran, Robert L. Moritz and Sachdev S. SidhuUniversity of Toronto, Institute for Systems Biology Washington, Hospital for Sick Children Toronto, Mount Sinai Hospital, Cornell University

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Advances in data‐independent acquisition massspectrometry towards comprehensive digital proteomelandscape2022Reta Birhanu Kitata, Jhih‐Ci Yang, Yu‐Ju ChenAcademia Sinica, National Yang Ming Chiao Tung University, National Taiwan University

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Noninvasive proteomic biomarkers for alcohol-related liver disease2022Lili Niu , Maja Thiele , Philipp E. Geyer, Ditlev Nytoft Rasmussen, Henry Emanuel Webel, Alberto Santos, Rajat Gupta, Florian Meier , Maximilian Strauss , Maria Kjaergaard , Katrine Lindvig, Suganya Jacobsen, Simon Rasmussen , Torben Hansen , Aleksander KUniversity of Copenhagen, Max Planck Institute of Biochemistry, Odense University Hospital, University of Southern Denmark, Jena University Hospital, University of Oxford, Pfizer Worldwide Research and Development

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Brain proteome profling implicates the complement and coagulation cascade in multiple system atrophy brain pathology2022Rasmus Rydbirk, Ole Østergaard, Jonas Folke, Casper Hempel, Brian DellaValle, Thomas L. Andresen, Annemette Løkkegaard, Anne‑Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik H. Danielsen, Lisette Salvesen, Charlotte C. Starhof, Sara BechCopenhagen University Hospital, University of Copenhagen, Technical University of Denmark, GLX Analytix ApS, Odense University Hospital, Aarhus University Hospital

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30-spdthermo-q-exactive-hf-x
Application of In-Cell Fast Photochemical Oxidation of Proteins for the Study of Organoids2022Raquel Shortt, Lisa M. JonesUniversity of Maryland, University of California

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Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF2022Patricia Skowronek, Marvin Thielert, Eugenia Voytik, Maria C. Tanzer, Fynn M. Hansen, Sander Willems, Özge Karayel, Andreas-David Brunner, Florian Meier, Matthias MannMax Planck Institute of Biochemistry, Jena University Hospital, University of Copenhagen, ,

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High-throughput quantitative proteomics using Zeno SWATH data-independent analysis (DIA) and the Evosep One system2022Ihor Batruch, Yves Le Blanc and Christie HunterSCIEX, , ,

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100-spd 200-spd 30-spd 60-spdsciex-zenotof-7600
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles2022Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Elke Kurz, Audun Kvalvaag, Lina Chen, Charity Ganskow, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Errin Johnson, Jesús A. Siller-Farfán, Omer DThe University of Oxford, Autónoma de Madrid, Centro Nacional de Investigaciones Cardiovasculares (CNIC), University of Oxford, Karolinska Institutet

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60-spdbruker-timstof-pro
Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients2022Marina Serrano-Maciá, Sofia Lachiondo-Ortega, Paula Iruzubieta, Naroa Goikoetxea-Usandizaga, Alexandre Bosch, Leire Egia-Mendikute, Borja Jiménez-Lasheras, Mikel Azkargorta, Félix Elortza, Diana Martinez-Redondo, Begoña Castro, Juan J. Lozano, Ruben NogueCIC bioGUNE-BRTA, IDIVAL, CIC bioGUNE, CIBEREHD, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Centro de Investigación Biomédica en Red, GAIN, Universidad de Cantabria, Ikerbasque & Basque Foundation for Science

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30-spdbruker-timstof-pro
Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms2022Marina Garcia-Moreno, Paul M. Jordan, Kerstin Günther, Therese Dau, Christian Fritzsch, Monika Vermes, Astrid Schoppa, Anita Ignatius, Britt Wildemann, Oliver Werz, Bettina Löffler & Lorena TuchscherrJena University Hospital, Friedrich Schiller University Jena, Leibniz Institute on Aging & University Medical Center Ulm

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30-spdthermo-orbitrap-exploris-480
High throughput and high confidence sequence variant analysis in therapeutic antibodies using Evosep One liquid chromatography tandem mass spectrometry with synthetic heavy peptides2022Tyler Greer, Reid O'Brien Johnson, Song Nie, Milos Cejkov, Xiaojing Zheng & Ning LiRegeneron Pharmaceuticals Inc

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30-spdthermo-orbitrap-fusion-lumos
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD62022Matthew E. Cockman, Yoichiro Sugimoto, Hamish B. Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R. Flynn, Joanna M. Kirkpatrick, Christopher J. Schofield and Peter J. RatcliffeFrancis Crick Institute

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30-spdthermo-orbitrap-fusion-lumos
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response2022Yuxin Mi, Katie L Burnham, Philip D Charles, Raphael Heilig, Iolanda Vendrell, Justin Whalley, Hew D Torrance, David B Antcliffe, Shaun M May, Matt J Neville, Georgina Berridge. Paula Hutton, Cyndi Goh, Jayachandran Radhakrishnan, Alexey Nesvizhskii,University of Oxford, Wellcome Genome Campus, Imperial College London, Queen Mary University of London, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, University of Michigan, Imperial College Healthcare NHS Trust

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100-spdbruker-timstof-pro
The addition of FAIMS increases targeted proteomics sensitivity from FFPE tumor biopsies2022Steve Sweet, David Chain, WenYu, Philip Martin, Marlon Rebelatto, Andrew Chambers, Fabiola Cecchi and Yeoun Jin KimAstraZeneca

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30-spdthermo-orbitrap-fusion-lumos
Analysis of context-specific KRAS-effectors (sub)complexes in Caco-2 cells2022Camille Ternet, Philipp Junk, Thomas Sevrin, Simona Catozzi, Giorgio Oliviero, Kieran Wynne and Christina KielUniversity College Dublin, University of Pavia

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Coordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC.2022Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte and Philip CohenUniversity of Dundee

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Biomarkers in Neurodegenerative Diseases: Proteomics Spotlight on ALS and Parkinson’s Disease2022Rekha Raghunathan, Kathleen Turajane and Li Chin WongInternational Journal of Molecular Sciences

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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes2022Maria Mercado-Gómez, Endika Prieto-Fernández, Naroa Goikoetxea-Usandizaga, Laura Vila-Vecilla, Mikel Azkargorta. Miren Bravo, Marina Serrano-Maciá, Leire Egia-Mendikute, Rubén Rodríguez-Agudo, Sofia Lachiondo-Ortega, So Young Lee, Alvaro Eguileor GinéCIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, IIS Hospital La Fe, University of Valencia, Basque Foundation for Science, University of the Basque Country, Centro de Investigación Biomédica En Red de Enferme

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Extended detection of anabolics misuse in high-throughput doping controls with the Evosep One2022Evosep

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100-spd
Structural studies reveal that endosomal cations promote formation of 2 infectious CVA9 A particles, facilitating RNA and VP4 release.2022Aušra Domanska, Zlatka Plavec, Visa Ruokolainen, Benita Löflund, Varpu Marjomäki, Sarah J ButcherFaculty of Biological and Environmental Sciences, Molecular and Integrative Bioscience Research Programme, and Helsinki Institute of Life Sciences-Institute of Biotechnology, University of Helsinki, Helsinki, Finland

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60-spdbruker-timstof-pro
Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines2022Sydney Sunna, Christine Bowen, Hollis Zeng, Struti Rayaprolu, Prateek Kumar, Pritha Bagchi, Duc M. Duong, Sara Bitarafan, Aditya Natu, Levi Wood, Nicholas T. Seyfried, Srikant RangarajuEmory University, Georgia Institute of Technology

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30-spdthermo-q-exactive
Rapid profiling of protein complex re-organization in perturbed systems2022Isabell Blau, Charlotte Nicod, Claudia Martelli, Peng Xue, Moritz Heusel Andreas Fossati, Federico Uliana, Fabian Frommelt, Ruedi Aabersold, Ben C. CollinsETH Zürich, Max Planck Institute of Biochemistry, Lund University, University of California San Francisco, J. David Gladstone Institutes, Queen's University of Belfast

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60-spdab-sciex-tripletof-6600
Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration2022Hyunggu Hahn, Carole Daly, John Little IV, Nicole A. Perry Hauser, Asuka Inoue, Bianca Plouffe, Alex R. B. ThomsenNew York University College of Dentistry, Queen’s University Belfast, Columbia University Vagelos College of Physicians and Surgeons, Tohoku University

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PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074, and THR1075) within the COR GTPase domain2022Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Sebastian Mathea, Prosenjit Pal, Pawel Lis, Matthew Taylor, Elena Purlyte, Robert Gourlay, Mark Dorward, Simone Weidlich, Rachel Toth, Nicole K. Polinski, Stefan Knapp, Francesca Tonelli & Dario R AlUniversity of Dundee, Collaborative Research Network, Johann Wolfgang Goethe University, AB Sciex

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30-spdthermo-orbitrap-exploris-240
Optimizing data points per protein increases protein identifications while maintaining quantitative precision in short gradient data-independent acquisition proteomics2022Joerg Doellinger, Christian Blumenscheit, Andy Schneider, Peter LaschRobert Koch-Institute

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60-spdbruker-timstof-pro
SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies Inactivation for Proteomics and Structural Studies2022Zlatka Plavec, Aušra Domanska, Xiaonan Liu, Pia Laine, Lars Paulin, Markku Varjosalo, Petri Auvinen, Sharon G. Wolf, Maria Anastasina, Sarah J. ButcherMolecular and Integrative Biosciences Research Programme, University of Helsinki, Weizmann Institute pf Science,

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60-spdbruker-timstof-pro
Common variable immunodeficiency in two kindreds with heterogeneous phenotypes caused by novel heterozygous NFKB1 mutations2022Frederik Staels, Kerstin De Keukeleere, Matias Kinnunen, Salla Keskitalo, Flaminia Lorenzetti, Michiel Vanmeert, Teresa Prezzemolo, Emanuela Pasciuto, Eveline Lescrinier, Xavier Bossuyt, Margaux Gerbaux, Mathijs Willemsen, Julika Neumann, Sien Van Loo, AnKU Leuven, University of Helsinki, University Hospitals Leuven, Babraham Institute

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60-spdbruker-timstof-pro
2-O-Methylation of the second transcribed nucleotide within the mRNA 5 cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion2022Karolina Drazkowska, Rafal Tomecki, Marcin Warminski, Natalia Baran, Dominik Cysewski, Anaıs Depaix, Renata Kasprzyk, Joanna Kowalska, Jacek Jemielity, Pawel J. SikorskiUniversity of Warsaw, Polish Academy of Sciences, Medical University of Bialystok

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30-spdthermo-orbitrap-exploris-480
A Parallelization Strategy for the Time Efficient Analysis of Thousands of LC/MS Runs in High-Performance Computing Environment2022Patrick van Zalm, Arthur Viodé, Kinga Smolen, Benoit Fatou, Arash Nemati Hayati, Christoph N. Schlaffner, Ofer Levy, Judith Steen, Hanno SteenBoston Children's Hospital

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Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse2022Melina Overhoff, Frederik Tellkamp, Simon Hess, Marianna Tolve, Janine Tutas, Marcel Faerfers, Lotte Ickert, Milad Mohammadi, Elodie De Bruyckere, Emmanouela Kallergi, Andrea Delle Vedove, Vassiliki Nikoletopoulou, Brunhilde Wirth, Joerg Isensee, Tim HuchUniversity of Cologne, University of Lausanne, Leibniz Institute for Molecular Pharmacology, German Center for Neurodegenerative Diseases

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On the potential of micro-flow LC-MS/MS in proteomics2022Yangyang Bian, Chunli Gao, Bernhard Kuster,Northwest University, Technical University of Munich

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300-spdab-sciex-tripletof-6600
Kinase Inhibitor Pulldown Assay (KiP) for Clinical Proteomics2022Alexander B Saltzman, Doug W Chan, Matthew V Holt, Junkai Wang, Eric J Jaehnig, Meenakshi Anurag, Purba Singh, Anna Malovannaya, Beom-Jun Kim, Matthew J EllisBaylor College of Medicine, MD Anderson Cancer Center, AstraZeneca,

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30-spdthermo-orbitrap-exploris-480
Enhanced drug delivery by a prodrug approach effectively relieves neuroinflammation in mice2022Ahmed Montaser, Janita Kuiri, Teemu Natunen, Pavel Hruska, David Potesil, Seppo Auriola, Mikko Hiltunen, Tetsuya Terasaki, Marko Lehtonen, Aaro Jalkanen, Kristiina M HuttunenUniversity of Eastern Finland, Masaryk University, Tohoku University,

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Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition2022Patricia Skowronek, Florian Krohs, Markus Lubeck, Georg Wallmann, Ericka Itang, Polina Koval, Maria Wahle, Marvin Thielert, Florian Meier, Sander Willems, Oliver Raether, Matthias MannMax Planck Institute of Biochemistry, Bruker Daltonics GmbH & Co. KG Bremen, Kyiv Academic University, Jena University Hospital, Bruker Belgium, NNF Center for Protein Research,,

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100-spd 60-spdbruker-timstof-pro
Slice-PASEF: fragmenting all ions for maximum sensitivity in proteomics2022Lukasz Szyrwiel, Ludwig Sinn, Markus Ralser, Vadim DemichevUniversitätsmedizin Berlin, University of Oxford

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200-spdbruker-timstof-pro
Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis2022I. García-Arnáeza, F. Romero-Gavilán, A. Cerqueira, F. Elortza, M. Azkargorta, F. Muñoz, M. Mata, J.J. Martín de Llano, J. Suay, M. Gurruchaga, I.GoñiaUniversity of the Basque Country, Universitat Jaume, Basque Research and Technology Alliance, Campus Universitario, iBoneLab SL, University of Valencia, Research Institute of the University Clinical Hospital of Valencia

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30-spdbruker-timstof-pro
Programmed death ligand 1 intracellular interactions with STAT3 and focal adhesion protein Paxillin facilitate lymphatic endothelial cell remodeling2022Johnathon B. Schafer, Erin D. Lucas, PhD, Monika Dzieciettkowska, Tadg Forward, Beth A. Jirón TamburiniUniversity of Colorado School of Medicine,

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Plasma proteomic profling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways2022Madeleine Johansson, HongYan, Charlotte Welinder, ÁkosVégvári, Viktor Hamrefors, Magnus Bäck, Richard Sutton, Artur FedorowskiSkåne University Hospital, Swedish National Infrastructure for Biological Mass Spectrometry, Karolinska Institutet, Lund University,

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60-spdbruker-timstof-pro
Two Subgroups within the GH43_36 α-l-Arabinofuranosidase Subfamily Hydrolyze Arabinosyl from Either Mono-or Disubstituted Xylosyl Units in Wheat Arabinoxylan2022Kai P. Leschonski, Svend G. Kaasgaard,Nikolaj Spodsberg, Kristian B. R. M. Krogh, Mirjam A. KabelNovozymes A/S, Wageningen University

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Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth2022Zilu Ye, Gülcan Kilic, Sally Dabelsteen, Irina N. Marinova, Jens F. B. Thøfner, Ming Song, Asha M. Rudjord-Levann, Ieva Bagdonaite, Sergey Y. Vakhrushev, Cord H. Brakebusch, Jesper V. Olsen, Hans H. WandallUniversity of Copenhagen

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30-spdthermo-orbitrap-exploris-480
Enhancing single-cell proteomics through tailored Data-Independent Acquisition and micropillar array-based chromatography2022Valdemaras Petrosius, Pedro Aragon-Fernandez, Nil Üresin, Teeradon Phlairaharn, Benjamin Furtwängler, Jeff op de Beeck, Simon Francis Thomsen, Ulrich auf dem Keller, Bo T. Porse, Erwin M. SchoofTechnical University of Denmark, University of Copenhagen

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Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage2022Irene González-Recio, Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Maria Mercado-Gómez, Rubén Rodríguez-Agudo, Sofía Lachiondo Ortega, Clàudia Gil-Pitarch, Carmen Fernández-Rodríguez, Donatello Castellana, Maria U. Latasa, Leticia AbeciCIC bioGUNE, Universidad de Navarra, Marqués de Valdecilla University Hospital, McGill University, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of the Basque Country (UPV/EHU), Silence Therapeutic

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Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway2022Valdemaras Petrosius, Jan Benada, Olaf Nielsen, Erwin Marten Schoof, Claus Storgaard SørensenUniversity of Copenhagen, Technical University of Denmark

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30-spdthermo-fisher-ultimate-3000
Pushing the boundaries for robust and high-throughput single cell analysis2022Evosep

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whisper-40spdbruker-timstof-scp
Rapid and robust PTM peptide mapping for biologics with the Evosep One and the SCIEX ZenoTOF 76002022Evosep, ,

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100-spd 300-spd 60-spdsciex-zenotof-7600
A complete, automated Opentrons OT-2 loading protocol for simplified sample loading of Evotip Pure2022Evosep, ,

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100-spd 500-spd whisper-40spdbruker-timstof-pro
Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease2022Yi‑Long Wang, Meng‑Ying Zhu, Zhe‑Feng Yuan, Xiao‑Yan Ren, Xiao‑Tong Guo, Yi Hua, Lu Xu, Cong‑Ying Zhao, Li‑Hua Jiang, Xin Zhang, Guo‑Xia Sheng, Pei‑Fang Jiang, Zheng‑Yan Zhao, Feng GaoZhejiang University School of Medicine

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thermo-q-exactive
Pushing the boundaries for robust and high-throughput single cell analysis with Whisper Flow technology powered by dia-PASEF2022Dorte B. Bekker-Jensen, Christoph Krisp, David Hartlmayr, Anjali Seth, Ole B. Hørning, Moritz Heusel, Magnus Huusfeldt, Andreia Almeida, Markus Lubeck, Gary Kruppa, Jarrod Sandow, Nicolai BacheEvosep Biosystems, Bruker Daltonics GmBH & Co. KG, Cellenion, IonOpticks, Bruker s.r.o, Brno

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whisper-40spdbruker-timstof-scp
A complete and automated sample preparation strategy for high-throughput and standardized proteomics, applied to a clinical cohort of patient plasma samples2022Dorte B. Bekker-Jensen, Florian Harking, Magnus Huusfeldt, Ole Østergaard, Lasse Falkenby, Line Vinderslev Iversen, Jakob Bunkenborg, Angie McArdle, Ole B. Hørning, Nicolai Bache, Jesper V. OlsenEvosep Biosystems, University of Copenhagen, Statens Serum Institut, Bispebjerg University Hospital,,

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500-spd whisper-40spdbruker-timstof-pro
Ultra-high sensitivity for targeted clinical proteomics using Evosep-MRM2022Angela McArdle, Dorte B. Bekker-Jensen, Bharath Kumar Raghuraman, Nicolai BacheEvosep Biosystems

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whisperagilent-6495-triple-quadrupole
MS-DAP Platform for Downstream Data Analysis of Label-Free Proteomics Uncovers Optimal Workflows in Benchmark Data Sets and Increased Sensitivity in Analysis of Alzheimer’s Biomarker Data2022Frank Koopmans, Ka Wan Li, Remco V. Klaassen, and August B. SmitVU University

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30-spdtimstof-pro
Hybrid-DIA: Intelligent Data Acquisition for Simultaneous Targeted and Discovery Phosphoproteomics in Single Spheroids2022Ana Martínez-Val, Kyle Fort, Claire Koenig, Leander Van der Hoeven, Giulia Franciosa, Thomas Moehring , Yasushi Ishihama, Yu-ju Chen, Alexander Makarov, Yue Xuan and Jesper V. OlsenNovo Nordisk Foundation Center for Protein Research, University of Copenhagen. Thermo Fisher Scientific. Kyoto University. Academia Sinica

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whisper-40spdthermo-orbitrap-exploris-480
A targeted multiplex mass spectrometry method for quantitation of abundant matrix and cellular proteins in formalin-fixed paraffin embedded arterial tissue2022Anne-Sofie Faarvang Thorsen, Lars Peter Schødt Riber, Lars Melholt Rasmussen and Martin OvergaardOdense University Hospital. University of Southern Denmark. Steno Diabetes Center Odense.

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60-spdthermo-altis-triple-quadrupole
Proteomic evaluation of human osteoblast responses to titanium implants over time2022Francisco Romero-Gavilán, Andreia Cerqueira, Iñaki García-Arnáez, Mikel Azkargorta, Félix Elortza, Marilo Gurruchaga, Isabel Goñi and Julio SuayUniversitat Jaume I, Universidad del País Vasco, CIC bioGUNE

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30-spdtimstof-pro
Insight into the antibacterial mechanism of Cuenriched sol–gel coatings employing proteomics2022Francisco Romero-Gavilán, Iñaki García-Arnáez, Andreia Cerqueira, Loredana Scalschi, Begonya Vicedo, Alejandro Villagrasa, Raúl Izquierdo, Mikel Azkargorta, Félix Elortza, Mariló Gurruchaga, Isabel Goñi and Julio SuayUniversitat Jaume I, Universidad del País Vasco, CIC bioGUNE

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timstof-pro
Chromatographic separation of peptides and proteins for characterization of proteomes2022Yu Liang, Lihua Zhang and Yukui ZhangChinese Academy of Science, ,

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100-spd 200-spd 60-spdthermo-orbitrap-exploris-480
Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD592022Kieran Brennan, Katrine F. Iversen, Alfonso Blanco-Fernández, Thomas Lund, Torben Plesner and Margaret M. Mc GeeUniversity College Dublin, University of Southern Denmark & Odense University Hospital

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30-spdbruker-timstof-pro
In situ digestion of alcohol-fixed cells for quantitative proteomics2022Atsushi Hatano, Tomoyo Takami and Masaki MatsumotoGraduate School of Medical and Dental Sciences and Niigata University

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Interactions of Viral Proteins from Pathogenic and Low or Non-Pathogenic Orthohantaviruses with Human Type I Interferon Signaling2021Giulia Gallo, Grégory Caignard, Karine Badonnel, Guillaume Chevreux, Samuel Terrier, Agnieszka Szemiel, Gleyder Roman-Sosa, Florian Binder, Quan Gu, Ana Da Silva Filipe, Rainer G. Ulrich, Alain Kohl, Damien Vitour, Noël Tordo & Myriam ErmonvalInstitut Pasteur, France. Ecole Doctorale Complexité du Vivant, France. UMR 1161 Virologie, France. BREED, INRAE, Université Paris-Saclay, France. Université de Paris, France. MRC-University of Glasgow Centre for Virus Research, UK. Institute of Novel and

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Crystal structure of bacterial cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication2021Paweena Chaoprasid, Peer Lukat, Sabrina Mühlen, Thomas Heidler, Emerich‐Mihai Gazdag, Shuangshuang Dong, Wenjie Bi, Christian Rüter, Marco Kirchenwitz, Anika Steffen, Lothar Jänsch, Theresia E B Stradal, Petra Dersch & Wulf BlankenfeldtUniversity of Münster, Germany. Helmholtz Centre for Infection Research, Germany. Deutsches Zentrum für Infektionsforschung, Germany. Technische Universität Braunschweig, Germany.

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Basement membrane stiffness determines metastases formation2021Raphael Reuten, Sina Zendehroud, Monica Nicolau, Lutz Fleischhauer, Anu Laitala, Stefanie Kiderlen, Denise Nikodemus, Lena Wullkopf, Sebastian Rune Nielsen, Sarah McNeilly, Carina Prein, Maria Rafaeva, Erwin M. Schoof, Benjamin Furtwängler, Bo T. Porse, HUniversity of Copenhagen, Denmark. Freie Universität Berlin, Germany. Munich University of Applied Sciences, Germany. Center for Nanoscience-CeNS, Germany. University of Glasgow, UK. Technical University of Denmark, Denmark. KU Leuven, Belgium. Queen Mary

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Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution2021Ana Martinez-Val, Dorte B. Bekker-Jensen, Sophia Steigerwald, Adi Mehta, Trung Tran, Krzysztof Sikorski, Estefanía Torres-Vega, Ewa Kwasniewicz, Sólveig Hlín Brynjólfsdóttir, Lisa B. Frankel, Rasmus Kjøbsted, Nicolai Krogh, Alicia Lundby, Simon Bekker-JenUniversity of Copenhagen, Denmark. Oslo University Hospital, Norway.

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R1441G but not G201S Mutation Enhances LRRK2 Mediated Rab10 phosporylation in human Peripheral blood neutrophils2021Ying Fan, Raja S. Nirujogi, Alicia Garrido, Javier Ruiz Martínez, Alberto Bergareche-Yarza, Elisabet Mondragón Rezola, Ana Vinagre Aragón, Ioana Croitoru, Ana Gorostidi Pagola, Laura Paternain Markinez, Roy Alcalay, Richard A. Hickman, Jonas Duering, NeriUniversity of Dundee, UK. Hospital Clínic de Barcelona, Spain. Universitat de Barcelona, Spain. Biodonostia Health Research Institute, Spain. Columbia University Medical Center, New York, USA. The Michael J Fox Foundation for Parkinson's Research, New Yor

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Molecular origin of blood-based infrared fingerprints2021Liudmila Voronina, Cristina Leonardo, Johannes B. Mueller-Reif, Philipp E. Geyer, Marinus Huber, Michael Trubetskov, Kosmas V. Kepesidis, Jürgen Behr, Matthias Mann, Ferenc Krausz & Mihaela ŽigmanDepartment of Physics, Ludwig Maximilian University of Munich, Germany. Max Planck Institute of Quantum Optics, Garching, Germany. Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,Germany. Novo Nordisk Foundation Cent

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The Host Interactome of Spike Expands the Tropism of SARS-CoV-22021Casimir Bamberger, Sandra Pankow, Salvador Martínez-Bartolomé, Jolene Diedrich, Robin Park & John Yates IIIDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA

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High-resolution longitudinal serum proteome trajectories in COVID-19 reveal patients-specific seroconversion2021Philipp E. Geyer, Florian M. Arend, Sophia Doll, Marie-Luise Louiset, Sebastian Virreira Winter, Johannes B. Müller-Reif, Furkan M. Torun, Michael Weigand, Peter Eichhorn, Mathias Bruegel, Maximilian T. Strauss, Lesca M. Holdt, Matthias Mann & Daniel TeupOmicEra Diagnostics GmbH, Germany. University Hospital, LMU Munich, Germany. University of Copenhagen, Denmark.

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SPIN – Species by Proteome Investigation2021Patrick L. Rüther, Immanuel M. Husic, Pernille Bangsgaard, Kristian M. Gregersen, Pernille Pantmann, Milena Carvalho, RitaM. Godinho, Lukas Friedl, Joao Cascalheira, Marie Louise S. Jørkov, Michael Benedetti, Jonathan Haws, Nuno Bicho, Frido Welker, EnricUniversity of Copenhagen, Denmark. University of Algarve, Portugal. University of Louisville, USA. University of North Carolina, USA. University of West Bohemia, Czech Republic. University of New Mexico, Albuquerque, USA. Museum Nordsjælland, Denmark. Roy, ,

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Whisper™ step-by-step guide2021Evosep

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Whisper is coming2021Evosep

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A beginner’s guide to Evosep2021Nicolai Bache, Alexey Chernobrovkin & Raja NirojogiEvosep, Pelago Bioscience, University of Dundee

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Covid-19 research with Evosep One2021Angela McArdle & Mathias TrostCedars Sinai, Newcastle University

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Rapid, robust and reproducible host-cell protein analysis with Evosep One2021Jiao Ma & Anders GiessingAstraZeneca, Novozymes, ,

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Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease2021Alexandra Pokhilko, Gaia Brezzo, Lahiru Handunnetthi, Raphael Heilig, Rachel Lennon, Colin Smith, Stuart M Allan, Alessandra Granata, Sanjay Sinha, Tao Wang, Hugh S Markus, Alexandra Naba, Roman Fischer, Tom Van Agtmael, Karen Horsburgh & M. Zameel CaderUniversity of Oxford, UK. University of Edinburgh, UK. University of Glasgow. UK. University of Manchester, UK. Manchester Academic Health Science Centre, UK. Cambridge Biomedical Campus, Hills Road, UK. University of Illinois at Chicago, USA.

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Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers2021Christoph H Mayr, Lukas M Simon, Gabriela Leuschner, Meshal Ansari, Janine Schniering, Philipp E Geyer, Ilias Angelidis, Maximilian Strunz, Pawandeep Singh, Nikolaus Kneidinger, Frank Reichenberger, Edith Silbernagel, Stephan Böhm, Heiko Adler, Michael LiHelmholtz Zentrum München, Munich, Germany. Ludwig‐Maximilians University (LMU) Munich, Munich, Germany. University Hospital Zurich, Zurich, Switzerland. Max Planck Institute of Biochemistry, Martinsried, Germany. Asklepios Fachkliniken Munich‐Gauting, Mu,

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A robust mass spectrometer for precision medicine – the Orbitrap Exploris 240 mass spectrometer for large-scale plasma protein profiling2021Michelle L Dubuke, Sitara Chauhan, Sarah Trusiak & Emily I. ChenThermo Fisher Scientific, United States

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High sensitivity dia-PASEF proteomics with DIA-NN and FragPipe2021Vadim Demichev, Fengchao Yu, Guo Ci Teo, Lukasz Szyrwiel, George A. Rosenberger, Jens Decker, Stephanie Kaspar-Schoenefeld, Kathryn S. Lilley, Michael Mülleder, Alexey I. Nesvizhskii & Markus RalserThe Francis Crick Institute, London, UK. Charité – Universitätsmedizin Berlin, Germany. University of Cambridge, UK. University of Michigan, Ann Arbor, USA. Columbia University, New York, USA. Bruker Daltonics, Bremen, Germany, ,

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The COVIDome Explorer Researcher Portal2021Kelly D. Sullivan, Matthew D. Galbraith, Kohl T. Kinning, Kyle Bartsch, Nik Levinsky, Paula Araya, Keith P. Smith, Ross E. Granrath, Jessica R. Shaw, Ryan Baxter, Kimberly R. Jordan, Seth Russell, Monika Dzieciatkowska, Julie A. Reisz, Fabia Gamboni, FranUniversity of Colorado, CO, USA. University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Colorado School of Public Health, Aurora, CO, USA.

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Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony2021Abigail J. Perrin, Claudine Bisson, Peter A. Faull, Matthew J. Renshaw, Rebecca A. Lees, Roland A. Fleck, Helen R. Saibil, Ambrosius P. Snijders, David A. Baker & Michael J. BlackmanThe Francis Crick Institute, London, UK. University of London, London, UK. King’s College London, London, UK. London School of Hygiene & Tropical Medicine, London, UK

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Standardized workflow for precise mid- and high-throughput proteomics of blood biofluids2021Angela Mc Ardle, Aleksandra Binek, Annie Moradian, Blandine Chazarin Orgel, Alejandro Rivas, Kirstin E. Washington, Conor Phebus, Danica-Mae Manalo, James Go, Vidya Venkatraman, Casey Johnson, Qin Fu, Susan Cheng, Koen Raedschelders, Justyna-Fert Bober, SCedars-Sinai Medical Center, Los Angeles, CA, United States. University College Dublin, Dublin, Ireland.

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Hemorrhage and saline resuscitation are associated with epigenetic and proteomic reprogramming in the rat lung2021Alexander Bonde, Trine G. Eskesen, Jacob Steinmetz, Erwin M. Schoof, Lene H.D. Blicher, Lars S. Rasmussen & Martin SillesenRigshospitalet, University of Copenhagen, Denmark. Technical University of Denmark, Lyngby, Denmark.

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Co-translational assembly and localized translation of nucleoporins in nuclear pore complex biogenesis2021Ophélie Lautier, Arianna Penzo, Jérôme Rouvière, Guillaume Chevreux, Louis Collet, Isabelle Loïodice, Angela Taddei, Frédéric Devaux, Martine A. Collart & Benoit PalancadeUniversité de Paris, Paris, France. Sorbonne Université, Paris, France. University of Geneva, Geneva, Switzerland.

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Unleashing the power of DIA combined with short gradients using Evosep One2021Florian Meier & Vadim DemchevFriedrich Shiller University, Jena, Germany. Francis Crick Institute, UK., ,

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High Sensitivity Evotips2021EvosepEvosep

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A fleet of Evosep One instruments supports a proteomics factory at Rapid Novor2021Evosep. Rapid NovorEvosep. Rapid Novor

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Inhibition of eEF2K synergizes with glutaminase inhibitors or 4EBP1 depletion to suppress growth of triple-negative breast cancer cells2021YoungJun Ju, Yaacov Ben-David, Daniela Rotin & Eldad ZacksenhausUniversity Health Network, Toronto, Canada. Chinese Academic of Sciences, Guiyang, China. Guizhou Medical University, Guiyang, China. The Hospital for Sick Children, Toronto, Canada.

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Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures2021Giulia Franciosa, Jos G. A. Smits, Sonia Minuzzo, Ana Martinez-Val, Stefano Indraccolo & Jesper V. OlsenUniversity of Padova, Padova, Italy. University of Copenhagen, Denmark.,

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An ultrasensitive method for analysis of viral spike N-glycoforms2021Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson & John R Yates IIIMassachusetts Institute of Technology and Harvard, Cambridge, MA, USA. The Scripps Research Institute, La Jolla, CA, USA.,

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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity2021COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium, Julian C Knight.University of Oxford

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Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses2021Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Audun Kvalvaag, Elke Kurz, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Jesús A. Siller-Farfán, Omer Dushek, Michal Maj, Erdinc Sezgin, Ben PeacoThe University of Oxford, Oxford, UK. Universidad Autónoma de Madrid, Madrid, Spain. Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. Karolinska Institutet, Stockholm, Sweden. MediCity, Nottingham, UK.

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Rapid and Accurate Detection of Aminoglycoside-Modifying Enzymes and 16S rRNA Methyltransferases by Targeted Liquid Chromatography-Tandem Mass2021Dimard E. Foudrainehttps, Nikolaos Strepisa, Corné H. W. Klaassenhttps, Merel N. Raaphorsta, Annelies Verbona, Theo M. Luiderb, Wil H. F. Goessensa & Lennard J. M.Erasmus MC University Medical Center, Rotterdam, The Netherlands

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Mass Spectrometry Provides a Highly Sensitive Noninvasive Means of Sequencing and Tracking M-Protein in the Blood of Multiple Myeloma Patients2021Zac McDonald, Paul Taylor, Mariya Liyasova, Qixin Liu & Bin MaRapid Novor, Canada

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Exploitation of the Secretory Pathway by SARS-CoV-2 Envelope2021Guy J Pearson, Malgorzata Broncel, Ambrosius P Snijders & Jeremy G CarltonKing’s College London, UK. The Francis Crick Institute, UK.

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A personalized mass spectrometry-based assay to monitor M-protein in multiple myeloma patients (EasyM)2021Mariya Liyasova, Zac McDonald, Paul Taylor, Kathleen Gorospe, Xin Xu, Chenyu Yao, Qixin Liu, Liqiang Yang, Eshetu G. Atenafu, Giovanni Piza, Bin Ma, Donna Reece, Suzanne TrudelRapid Novor, Canada. University of Waterloo, Canada. Princess Margaret Cancer Centre, Canada., ,

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AlphaPept, a modern and open framework for MS-based proteomics2021Maximilian T. Strauss, Isabell Bludau, Wen-Feng Zeng, Eugenia Voytik, Constantin Ammar, Julia Schessner, Rajesh Ilango, Michelle Gill, Florian Meier, Sander Willems & Matthias MannMax Planck Institute of Biochemistry, Martinsried, Germany. University of Copenhagen, Denmark. Nvidia Corporation, Santa Clara, CA, USA. OmicEra Diagnostics GmbH, Planegg, Germany. Jena University Hospital, Jena, Germany.

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Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study2021IMPACC Manuscript Writing TeamIMPACC

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A universal peptide matrix interactomics approach to disclose motif dependent protein binding2021Evelyn Ramberger, Lorena Suarez-Artiles, Daniel Perez-Hernandez, Mohamad Haji, Oliver Popp, Ulf Reimer, Achim Leutz, Gunnar Dittmar & Philipp MertinsMax Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. Luxembourg Institute of Health, Luxembourg. JPT Peptide Technologies GmbH, Berlin, Germany. Humboldt University of Berlin, Berlin, Germany. University of Luxembourg

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PD-L1 Overexpression, SWI/SNF Complex Deregulation, and Profound Transcriptomic Changes Characterize Cancer-Dependent Exhaustion of Persistently Activated CD4+ T Cells2021Iga Jancewicz, Joanna Szarkowska, Ryszard Konopinski, Malgorzata Stachowiak, Monika Swiatek, Katarzyna Blachnio, Szymon Kubala, Paulina Oksinska, Pawel Cwiek, Natalia Rusetska, Agnieszka Tupalska, Natalia Zeber-Lubecka, Ewa Grabowska, Bianka Swiderska,Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. Polish Academy of Sciences, 02-106 Warsaw, Poland. University Hospital Basel and University of Basel, 4001 Basel, Switzerland. Centre of Postgraduate Medical Education, 01-8

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Time evolution of PEG-shedding and serum protein coronation determines the cell uptake kinetics and delivery of lipid nanoparticle formulated mRNA2021A. Gallud, M. J. Munson, K. Liu, A. Idström, H. M. G. Barriga, S. R. Tabaei, N. Aliakbarinodehi, M. Ojansivu, Q. Lubart, J. J. Doutch, M. N. Holme, L. Evenäs, L. Lindfors, M. M. Stevens, A. Collén, A. Sabirsh, F. Höök, E. K. Esbjörner.Chalmers University of Technology, Gothenburg, Sweden. AstraZeneca, Gothenburg, Sweden. Karolinska Institute, Stockholm, Sweden. Rutherford Appleton Laboratory, Didcot, UK. Imperial College London, UK.

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A deeper look at carrier proteome effects for single-cell proteomics2021Zilu Ye, Tanveer Batth, Patrick L. Rüther, Jesper V. OlsenUniversity of Copenhagen

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Deep neural network for detecting arbitrary precision peptide features through attention based segmentation2021Fatema Tuz Zohora, M. Ziaur Rahman, Ngoc Hieu Tran, Lei Xin, Baozhen Shan & Ming LiUniversity of Waterloo, Waterloo, Canada. Bioinformatics Solutions Inc., Waterloo, Canada.

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AlphaTims: Indexing Trapped Ion Mobility Spectrometry–TOF Data for Fast and Easy Accession and Visualization2021Sander Willems, Eugenia Voytik, Patricia Skowronek, Maximilian T. Strauss & Matthias MannMax Planck Institute of Biochemistry, Martinsried, Germany. OmicEra Diagnostics GmbH, Planegg, Germany. University of Copenhagen, Copenhagen, Denmark,

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Discovery Proteomics for COVID-19: Where We Are Now2021Angela McArdle, Kirstin E. Washington, Blandine Chazarin Orgel, Aleksandra Binek, Danica-Mae Manalo, Alejandro Rivas, Matthew Ayres, Rakhi Pandey, Connor Phebus, Koen Raedschelders, Justyna Fert-Bober & Jennifer E Van EykCedars-Sinai Medical Center, Los Angeles, California, United States

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Plasma Proteomics with the Evosep One2021Roman Fischer & Lili NiuUniversity of Oxford & Novo Nordisk Foundation Center for Protein Research,

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Targeted Workflows with Evosep One2021Michael Maccoss & Vivian DelcourtUniversity of Washington & Laboratoire Des Courses Hippiques

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High-Throughput Drug Discovery with the Evosep One2021Casimir Bamberger & Tanveer S. BatthScripps Research Institute & Novo Nordisk Foundation Center for Protein Research

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Evaluation of Disposable Trap Column nanoLC–FAIMS–MS/MS for the Proteomic Analysis of FFPE Tissue2021Stephan Eckert, Yun-Chien Chang, Florian P. Bayer, Matthew The, Peer-Hendrik Kuhn, Wilko Weichert & Bernhard KusterTechnical University of Munich, Munich, Germany., ,

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DebaryOmics: an integrative –omics study to understand the halophilic behaviour of Debaryomyces hansenii2021Clara Navarrete, Benjamín J. Sánchez, Simonas Savickas, José L. MartínezTechnical University of Denmark. Denmark.

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Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk2021Beate Vestad, Tuula A. Nyman, Malene Hove‑Skovsgaard, Maria Stensland, Hedda Hoel, Anne‑Marie Siebke Trøseid, Trude Aspelin, Hans Christian D. Aass, Maija Puhka, Johannes R. Hov, Susanne Dam Nielsen, Reidun Øvstebø & Marius TrøseidOslo University Hospital Rikshospitalet, Oslo, Norway. University of Oslo, Oslo, Norway. Norwegian Society for Extracellular Vesicles, Oslo, Norway. University Hospital of Copenhagen Rigshospitalet, Copenhagen, Denmark. Lovisenberg Diaconal Hospital, Oslo

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Development of a Standardized Microflow LC Gradient to Enable Sensitive and Long-Term Detection of Synthetic Anabolic-Androgenic Steroids for High-Throughput Doping Controls2021Vivian Delcourt, Patrice Garcia, Isabelle Pottier, Nasrine Mansoibou, Nicolai Bache, Yohan Glavieux, Benjamin Chabot, Isabelle Perot, Isabelle Perot, François André, Benoit Loup, Agnès Barnabé, Marie-Agnès Popot & Ludovic Bailly-ChouriberryGIE-LCH, Laboratoire Des Courses Hippiques, France. Evosep.

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Automated sample prep workflows2021Philipp E. Geyer & Dorte Bekker-JensenOmicera Diagnostics, Evosep

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FFPE Tissue Analysis on the Evosep One2021Bernhard Kuster & Lisa SchweizerTechnical University of Munich, Max Planck Institute of Biochemistry

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Whisper is here2021Christoph Krisp & Angela KruseBruker, Vanderbilt University

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Fully Automated High-Throughput Host Cell Protein Analysis of Highly Diverse Samples2021Anders Giessing

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Data independent acquisition enables deep and fast label-free dynamic organellar mapping2021Julia P. Schessner, Vincent Albrecht, Alexandra K. Davies, Pavel Sinitcyn & Georg H.H. BornerMax-Planck Institute of Biochemistry, Martinsried, Germany,

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The social architecture of an in-depth cellular protein interactome2021André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau & Matthias MannMax-Planck Institute of Biochemistry, Martinsried, Germany

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Ultra-high sensitivity proteomics on the timsTOF SCP2021Nagarjuna Nagaraj, Thomas Kosinski, Amalia Apalategui Pierre-Olivier Schmit, Markus Lubeck, Oliver Raether & Gary KruppaBruker, Germany.

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Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase2021Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley & Alessandro CostaThe Francis Crick Institute, London, UK

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The setup and optimization of a complete global proteomics two-dimensional liquid chromatography system, using Spider Fractionation2021Eris Aas BakketeigUniversity of Oslo, Oslo, Norway

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Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics2021Roger Moreno-Justicia, Alba Gonzalez-Franquesa, Ben Stocks, Atul S. DeshmukhNovo Nordisk Foundation (NNF), Copenhagen Denmark

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Ultra sensitive and high throughput proteomics on the standardized Evosep One platform2021Jesper Olsen, Erwin M. SchoofUniversity of Copenhagen, Technical University of Denmark,

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Covalent Protein Painting Reveals Structural Changes In The Proteome In Alzheimer Disease2020Scripps Research Institute, United States

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A Compact Quadrupole-Orbitrap Mass Spectrometer With Faims Interface Improves Proteome Coverage In Short Lc Gradients2020Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ,

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Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles2020University of Southern Denmark

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In-Depth Characterization of Staurosporine Induced Proteome Thermal Stability Changes2020Pelago Biosciences, Sweden

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A paired liver biopsy and plasma proteomics study reveals circulating biomarkers for alcohol-related liver disease2020Max Planck Institute of Biochemistry, Martinsried, Germany and Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level2020University of Colorado, US

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Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV2020Max Planck Institute of Biochemistry, Martinsried, Germany,

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Development of mass spectrometry-based targeted assay for direct detection of novel SARS-CoV-2 coronavirus from clinical specimens2020Mayo Clinic Rochester, United States,

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Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients2020University of Colorado, United States

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Advancing Interactomics Workflows with 4D-Proteomics on the timsTOF Pro2020Max Planck Institute of Biochemistry, Martinsried, Germany

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An Ultra High-Throughput Plasma Protein Profiling (uHTPPP) Workflow Using a Modified Quadrupole-Orbitrap Mass Spectrometer2020Thermo Fisher Scientific, United States,

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Consistency, consistency – Automated Sample Prep for Translational Proteomics2020Thermo Fisher Scientific, United States

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Fast and reproducible phosphoproteomics using MagReSyn® Amine and Tim-IMAC HP magnetic beads and the Evosep One2020Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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MaxQuant software for ion moiblity enhanced shotgun proteomics2020Bruker Daltonics, Germany

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High-throughput 4D-Proteomics – Application of dia-PASEF® and the Evosep One for short gradients2020Bruker Daltonics, Germany, , ,

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Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis2020Technical University of Denmark

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Sensitive, Rapid, Robust and Reproducible Workflow for Host Cell Protein Profiling in Biopharmaceutical Process Development2020Glaxo Smith Kline, Unites States,

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High-throughput proteomics with Evosep One2020Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ,

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Improving proteome coverage and peptide identification rates in short LC gradients2020Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ,

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A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism2020SickKids Proteomics, Analytics, Robotics, and Chemical Biology Centre, Canada

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Increasing proteome coverage using cysteine-specific DIA Mass spectrometry – Cys-DIA2020University of Southern Denmark

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High dynamic range proteome analysis with BoxCar DIA and super-resolution Orbitrap mass spectrometry2020Max Planck Institute of Biochemistry, Martinsried, Germany,

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Robust and Reprodusible Protein Quantification in Plasma Using the Evosep One and the Agilent 6495 Triple Quadrupole LC/MS2020Agilent Technologies, United States

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A tale of two tails – efficient profiling of protein degraders by specific functional and target engagement readouts2020Pelago Biosciences, Sweden

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New Orbitrap Exploris 480 Mass Spectrometer Coupled with Evosep One2020Thermo Fisher Scientific, United States, ,

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High throughput proteome and phosphorpoteome sample processing coupled to fast gradient DIA2020Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark, ,

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diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisition2020Florian Meier, Andreas-David Brunner, Max Frank, Annie Ha, Isabell Bludau, Eugenia Voytik, Stephanie Kaspar-Schoenefeld, Markus Lubeck, Oliver Raether, Nicolai Bache, Ruedi Aebersold, Ben C. Collins, Hannes L. Röst & Matthias MannMax Planck Institute of Biochemistry, Martinsried, Germany. Bruker Daltonik, Germany. ETH Zürich, Switzerland. University of Belfast, United Kingdom. University of Toronto, Canada., ,

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Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites2020Raja S Nirujogi, Francesca Tonelli, Matthew Taylor, Pawel Lis, Alexander Zimprich, Esther Sammler & Dario R AlessiUniversity of Dundee, United States. Medical University of Vienna, Austria.,

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Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms2020Asad U. Malik, Athanasios Karapetsas, Raja S. Nirujogi, Sebastian Mathea, Prosenjit Pal, Pawel Lis, Matthew Taylor, Elena Purlyte, Robert Gourlay, Mark Dorward, Simone Weidlich, Rachel Toth, Nicole K. Polinski, Stefan Knapp, Francesca Tonelli & Dario R AlUniversity of Dundee, United Kingdom. Johann Wolfgang Goethe University, Germany. Michael J Fox Foundation for Parkinson’s Research, United States.

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Seroconversion stages COVID19 into distinct pathophysiological states2020Matthew D. Galbraith, Kohl T. Kinning, Kelly D. Sullivan, Ryan Baxter, Paula Araya, Kimberly R. Jordan, Seth Russell, Keith P. Smith, Ross E. Granrath, Jessica Shaw, Monika Dzieciatkowska, Tusharkanti Ghosh, Andrew A. Monte, Angelo D’Alessandro, Kirk C. HUniversity of Colorado, United States.

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ABPP-HT – high-throughput activity-based profiling of deubiquitylating enzyme inhibitors in a cellular context2020Hannah Jones, Raphael Heilig, Roman Fischer, Benedikt M Kessler & Adan Pinto-FernandezUniversity of Oxford, United Kingdom.

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Fluvastatin mitigates SARS-CoV-2 infection in human lung cells2020Francisco J. Zapatero-Belinchón, Rebecca Moeller, Lisa Lasswitz, Marco van Ham, Miriam Becker, Graham Brogden, Ebba Rosendal, Wenjie Bi, Belén Carriquí, Koushikul Islam, Annasara Lenman, Antonia P. Gunesch, Jared Kirui, Thomas Pietschmann, Anna K Överby,Medical School Hannover, Germany. Helmholtz Centre for Infection Research, Germany. University of Veterinary Medicine Hannover, Germany. Umeå University, Sweden. German Centre for Infection Research (DZIF), Germany.

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EVOSEP+2020Evosep

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Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation2020Andreas-David Brunner, Marvin Thielert, Catherine Vasilopoulou, Constantin Ammar, Fabian Coscia, Andreas Mund, Ole B. Horning, Nicolai Bache, Amalia Apalategui, Markus Lubeck, Oliver Raether, Melvin A. Park, Sabrina Richter, David S. Fischer, Fabian J. ThMax Planck Institute of Biochemistry, Martinsried, Germany. Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark. Evosep Biosystems, Denmark. Bruker Daltonik, Germany and United States. Helmholtz Zentrum München, Germany.,

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Fast Confirmatory Analysis of Rhuepos in Plasma for Horseracing Doping Control2019Le Laboratoire des Courses Hippiques (LCH), France

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Study: Increased De Novo Protein Sequencing Coverage With Optimal Protease Cocktail2019Rapid Novor, Canada

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Accurate Detection Of The Four Most Prevalent Carbapenemases In E. Coli And K. Pneumoniae By High-Resolution Mass Spectrometry2019Erasmus MC, The Netherlands

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Advanced Host Cell Protein (Hcp) Analysis With Tims Qtof Ms Powers Biopharmaceutical Development 2019Bruker Daltonics, Germany

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Increasing Throughput: From Pre-Clinical Models To Protein Complexes2019ETH Zürich, Switzerland

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Evosep One Enables Robust Deep Proteome Coverage Using Tandem Mass Tags While Significantly Reducing Instrument Time2019SickKids Proteomics, Analytics, Robotics, and Chemical Biology Centre, Canada,

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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites2019Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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Scalable and Automated Plasma Workflow Based on the Thermo Scientific Q Exactive HF-X MS Platform2019Thermo Fisher Scientific, United States, ,

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Plasma proteomics goes high-throughput – timsTOF Pro with PASEF and 4D feature alignment to quantify 500 plasma proteins in 11.5 min2019Bruker Daltonics, Germany

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Using Artificial Intelligence on Ultrafast LC-MSMS-DIA runs for Bacterial Identification in Urine2019CHU Québec Université Laval Research Center, Canada, ,

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Targeted assay development for quantifying protein half-life over a range of mouse tissues2019Glaxo Smith Kline, Unites States

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Peptidomic analysis of urine from youths with early type 1 diabetes reveals novel bioactivity of uromodulin peptides in vitro2019SickKids Proteomics, Analytics, Robotics, and Chemical Biology Centre, Canada

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Powerful pairing of technologies and analytical approaches2019Thomas AngelGlaxoSmithKline

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Evosep One: A Separation Tool Designed for Clinical Omics2019Evosep

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Improve and enhance your proteome coverage with the Performance column2019Evosep,

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Unleashing the true power of DIA/SWATH data acquisition with short gradients – Rapid profiling of pre-clinical models and proteome dynamics2019Evosep

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High-Throughput Proteomics Quantification Enabled by Fast LC Separation and Advanced PRM Acquisition2018Thermo Fisher Scientific, United States, ,

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timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics2018Bruker Daltonics, Germany, ,

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Rapid proteome analyses using the Evosep One2018Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark

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Development of a Novel LC Concept for Clinical Proteomics2018Max Planck Institute of Biochemistry, Martinsried and Bruker Daltonics, Germany

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Clinical proteomics2018Max Planck Institute of Biochemistry, Martinsried, Germany

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Online parallel accumulation – serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer2018Max Planck Institute of Biochemistry, Martinsried and Bruker Daltonics, Germany

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A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-Robust Proteomics2018Max Planck Institute of Biochemistry, Martinsried Germany and Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark60-spdthermo-q-exactive-hf-x
How to get Speed and Depth in yout Host Cell Protein2018Bruker Daltonics, Germany

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Development of a robust and reprodusible method for detection of citrullination in complex samples2018University of Southern Denmark, Denmark

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Optimizing data processing parameters for samples acquired on instruments using Advanced Peak Determination2018Thermo Fisher Scientific, United States

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Introducing the Evosep One – Instrument Overview2017

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Gradient off-set focusing HPLC insturment for robust and high throughput clinical proteomics2017

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Evosep One Field Test at the Max-Planck Institute of Biochemistry2017

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Tech note: Evosep One: A gradient off-set focusing HPLC instrument for robust and high throughput proteomics2017

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