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Evaluation of Disposable Trap Column nanoLC–FAIMS–MS/MS for the Proteomic Analysis of FFPE Tissue

by Eva Bryderup

This publication by the Kuster group presents a robust workflow to support the analysis of large cohorts of patient samples using formalin-fixed paraffin-embedded FFPE tissue. They make use of online fractionation by FAIMS requiring 50% less sample than conventional...

Evosep introduces a novel separation solution designed for clinical omics at HUPO 2017

by Eva Bryderup

Evosep aims to improve quality of life and patient care by radically innovating protein based clinical diagnostics. We will make sample preparation and separation for mass spectrometry analysis 100 times more robust and 10 times faster to enable truly large cohort studies and provide the foundation for precision medicine.

What matters in clinical proteomics? 2. The need for standardization

by Eva Bryderup

Many areas in clinical proteomics could benefit from a broader adoption of liquid chromatography mass spectrometry (LC/MS) methods. What needs to be done to make LC/MS a standard technique in the clinic?

What matters in clinical proteomics? 1. Challenges of large cohort studies

by Eva Bryderup

Cohort studies are essential in the discovery and validation of protein biomarkers. Every day, clinical proteomics labs evaluate patient samples to correlate protein patterns with a specific status – e.g., healthy vs. pathogenic, or therapeutically responsive vs. non-responsive.

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