Evosep One in the Clinical Biochemistry Lab
available on demand
Clinical biochemistry laboratories worldwide measure millions of samples daily from various body fluids such as blood and urine. A growing part of these analyses are performed with LC-MS/MS and especially for diagnostic niches of laboratory medicine, where superior analytical specificity is superior to immunoassays.
In this webinar, you can meet users from this research area and learn about their work and how they have implemented the Evosep One for routine analyses.
Why, how and when ms-based proteomics in laboratory medicine
Talk by Nicolai Jacob Wewer Albrechtsen, Associate Professor at Clinical Proteomics and Metabolism, NNF Center for Protein Research, University of Copenhagen, Denmark
Millions of samples are being analyzed every day to diagnose, monitor and prognose patients. In most hospitalts this is performed by a department of laboratory medicine using enzyme linked assays, radioimmunoassays and even gel-electrophoreses. More than 50% of every analyses orded at a hospital or at your own general practioneers is a protein. Currently, single assays are used to profile our patients and for decision making.
MS-based proteomics is not used in laboratory medicine for routine diagnostics. In this talk I will discuss how we have been exploring MS-based proteomics for clinical diagnostics for both common and rare diseases and finally I am eager to share our visions on how we believe MS-based proteomics may provide faster and better patient care.
Targeted Proteomics in Biomarker Development and Clinical Diagnostics
Martin Overgaard, Biochemist, Associate Professor, PhD, Department of Clinical Biochemistry Odense University Hospital, Odense, Denmark and Department of Clinical Research, SDU, University of Southern Denmark, Odense, Denmark
Mass spectrometry-based targeted proteomics workflows have within the last decade developed immensely in terms of automation, throughput and robustness – a prerequisite for implementation in the routine clinical biochemistry lab.
In this webinar, I will share my views on the challenges remaining ahead for implementing targeted protein assays as clinical lab tests, and provide examples of applications of MRM-based assays in arterial disease pathophysiology, diabetes and cancer follow-up diagnostics focusing on either multiplexing, high sensitivity or high specificity analysis.