A beginner’s guide to Evosep

This webinar is part of our Evosep webinar series and hosted by Nicolai Bache, Evosep. Nicolai Bache introduces the basics of the Evosep technology, while Alexey Chernobrovkin and Raja Nirojogi share their experience with the Evosep One and present their own...

CPP reveals structural changes in the proteome in Alzheimer disease

Neurodegenerative diseases are characterized by an accumulation of misfolded proteins. Cells normally recognize misfolded proteins and attempt to refold or to pass them on for proteasomal degradation. Chaperone proteins are central to recognizing and in refolding client proteins. When chaperone proteins fail to fulfill this function, conformationally altered proteins accumulate and can cause cell death.

Improving proteome coverage in short LC gradients

In a collaboration with Thermo Fisher Scientific, the Olsen Group and Novo Nordisk Foundation Center for Protein Research have described the new Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer for high-throughput analyses with short gradients using the Evosep One.

Standardized workflows for large cohort plasma profiling

Together, Thermo Fisher Scientific and Evosep are on a joint mission to develop standardized and scalable plasma protein quantitative profiling workflows. Our recent developments have been featured in an application note by the Precision Medicine Science Centre led by Dr. Emily Chen.

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